Search clinical trials for: Intravitreal Ranibizumab

Total 948 results

Johns Hopkins University
Juvenile Diabetes Research Foundation; iCo Therapeutics Inc.

Terminated

A Randomized, Multi-center, Phase II Study of the Safety, Tolerability and Bioactivity of Repeated Intravitreal Injections of iCo-007 as Monotherapy or in Combination With Ranibizumab or Laser Photocoagulation in the Treatment of Diabetic Macular Edema (the iDEAL Study) (iDEAL)

Diabetic Macular Edema

United States
Yonsei University

Recruiting

A Clinical Trial to Evaluate Efficacy of Once or Twice ZOledronic Acid After Different Duration of denOsumMab Administration in Postmenopausal Women With Osteoporosis (ZOOM Study)

Osteoporosis

Korea, Republic of
GenSight Biologics

Completed

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE) (REVERSE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, Germany, Italy, France
Hoffmann-La Roche

Completed

Study to Evaluate Home Vision Testing in Participants Who Receive Ranibizumab (Lucentis®)

Macular Degeneration | Macular Edema

United States
University of Leipzig

Completed

Proof of Concept Study of Re-treatment in BRVO With Ranibizumab Guided by OCT (RabOCT)

Branch Retinal Vein Occlusion

Germany
National Eye Institute (NEI)

Completed

Ranibizumab Injections to Treat Macular Telangiectasia With New Blood Vessel Growth

Neovascularization

United States
Novartis Pharmaceuticals

Withdrawn

CANadian Study in Patients With Wet AMD, Evaluating the Efficacy and Safety of Switching From Intravitreal Aflibercept to RanIbizumab (CANARI)

Wet Age-related Macular Degeneration (Wet AMD)
Bayer

Completed

Study to Assess the EffectiVeness of exIsting Anti-vascular Endothelial groWth Factor (Anti-VEGF) Treatment Regimens in Patients With Wet Age-related Macular Degeneration (REVIEW)

Macular Degeneration

Portugal
Alcon, a Novartis Company

Completed

LHA510 Proof-of-Concept Study as a Maintenance Therapy for Patients With Wet Age-Related Macular Degeneration

Exudative Age-Related Macular Degeneration

United States
Azza Mohamed Ahmed Said
Ain Shams University

Unknown

Suprachoroidal Injection of Triamcinolone Acetonide for Management of Diabetic Macular Edema (SCI)

Efficacy | Safety

Egypt
University of Sao Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Intravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma.

Retinal Degeneration | Primary Open-angle Glaucoma

Brazil
Albert Schweitzer Hospital

Completed

Treatment of Non-falciparum Malaria

Acute Non-falciparum Malaria

Gabon
Novartis Pharmaceuticals

Completed

Rainbow Extension Study (RainbowExt)

Retinopathy of Prematurity (ROP)

United States, Austria, Belgium, Croatia, Czechia, Denmark, Egypt, France, Germany, Greece, Hungary, India, Italy, Japan, Malaysia, Romania, Russian Federation, Saudi Arabia, Slovakia, Taiwan, Turkey, United Kingdom, Lithuania, Estonia
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab 0.5 mg Administered as Two Alternative Dosing Regimens in Chinese Patients With nAMD (Age Related Macular Degeneration) (DRAGON)

Neovascular Age-related Macular Degeneration

China
Vitreous -Retina- Macula Consultants of New York
Genentech, Inc.

Completed

A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study) (LAST)

Age Related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Two Treatment Regimens of 0.5 mg Ranibizumab Intravitreal Injections Guided by Functional and/or Anatomical Criteria, in Patients With Neovascular Age-related Macular Degeneration (OCTAVE)

Neovascular Age-related Macular Degeneration

Germany, Turkey, Austria, Canada, Czechia, United Kingdom, Hungary, Italy, Lithuania, Guatemala, France, Ireland, Argentina, Portugal, Spain, Sweden, Greece, Switzerland, Slovakia, Finland, Netherlands, Colombia, Mexico, Panama
National Eye Institute (NEI)

Completed

Ranibizumab Injections to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome

Von Hippel-Lindau Syndrome

United States
Novartis Pharmaceuticals

Completed

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting (LUMINOUS)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age Related Macular Degeneration | Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion

Spain, China, Colombia, Korea, Republic of, Belgium, Greece, Japan, Russian Federation, Turkey, United Kingdom, Egypt, Germany, Australia, Canada, France, Austria, Hong Kong, Hungary, Israel, Netherlands, Peru, Singapore, Slovakia, Sl... and more
Novartis Pharmaceuticals

Completed

Ranibizumab Treatment of Diabetic Macular Oedema With Bimonthly Monitoring After a Phase of Initial Treatment (RELIGHT)

Diabetic Retinopathy | Macular Oedema

United Kingdom
Mie University

Unknown

Predictive Factors of Ranibizumab Treatment in Macular Edema With CRVO (CRVO)

Central Retinal Vein Occlusion

Japan
Allegro Ophthalmics, LLC
Duke University; Trial Runners, LLC

Completed

A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy

Non-Proliferative Diabetic Retinopathy

United States
Subhransu K. Ray, M.D., Ph.D.
Bay Area Retina Associates

Completed

A Prospective Study Comparing Ranibizumab Plus Dexamethasone Combination Therapy Versus Ranibizumab Monotherapy for Wet AMD (Lucedex)

Exudative Age-Related Macular Degeneration

United States
IRCCS San Raffaele

Completed

Retrospective Observational Comparison Study Between Ustekinumab and Tofacitinib as Third Line Therapy in a Multicenter Cohort of Patients With Refractory Ulcerative Colitis.

Ulcerative Colitis

Italy
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Assessment of Visual Acuity in Patients With Polypoidal Choroidal Vasculopathy and Aflibercept Treatment (PCV)

Polypoidal Choroidal Vasculopathy

France
Sinocelltech Ltd.

Recruiting

This Study Will Compare the Efficacy and Safety of SCT510A Administered by Intravitreal Injection (IVT) With Ranibizumab in Patients With wAMD

Wet Age-related Macular Degeneration

China
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

601 Versus Ranibizumab in Patients With Pathological Myopic Choroidal Neovascularization (pmCNV)

Pathological Myopic Choroidal Neovascularization

China
University of California, San Francisco
Genentech, Inc.

Terminated

Ranibizumab in Preventing Failure of Ahmed Valve Glaucoma Surgery

Glaucoma

United States
Novartis Pharmaceuticals

Completed

Observation of Treatment Patterns With Lucentis® in Real-life Conditions in All Approved Indications (PACIFIC)

Neovascular (Wet) Age-related Macular Degeneration

Germany, Switzerland, Netherlands
Second Military Medical University

Unknown

Anti-VEGF Intravitreous Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery (Anti-VEGF)

Diabetic Macular Edema | Cataract

China
Johannes Gutenberg University Mainz
Novartis

Completed

Functional and Structural Outcomes in Neovascular Age-related Macular Degeneration (CAPTAIN)

Neovascular Age-related Macular Degeneration

Germany
California Retina Consultants
Genentech, Inc.

Completed

Ranibizumab 0.5mg and 2.0mg to Treat Diabetic Macular Edema in Patients With Poor Response to Bevacizumab (REEF)

Diabetic Macular Edema

United States
University of California, San Diego
Genentech, Inc.

Withdrawn

Ranibizumab for the Management of Recurrent Nosebleeds in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Hereditary Hemorrhagic Telangiectasia (HHT) | Nosebleeds
University Health Network, Toronto

Completed

Wet AMD Recurrence Rate in Patients Stable on Three Month Ranibizumab Dosing

Age Related Macular Degeneration

Canada
University of Melbourne

Completed

Study to Investigate the Safety and Efficacy of Ranibizumab in Patients With Choroidal Neovascularisation Due to Causes Other Than Age Related Macular Degeneration

Choroidal Neovascularization | Retinal Pigment Epithelial Detachment

Australia
Retina Institute of Hawaii

Completed

Investigates Improvement in Vision Following Switching From Avastin and Macugen Over to Lucentis

Wet AMD

United States
Shields, Shields and Associates

Unknown

Intravitreal Ranibizumab for the Prevention of Radiation Maculopathy Following Plaque Radiotherapy

Uveal Melanoma | Radiation Retinopathy | Radiation Maculopathy

United States
Novartis Pharmaceuticals

Recruiting

A 24-week Study Evaluating the Effectiveness and Safety of Lucentis® 0.2mg in Retinopathy of Prematurity Participants in China

Retinopathy of Prematurity

China
Sun Yat-sen University

Unknown

Visual Outcomes and the Predictive Factors in Chinese Patients With Diabetic Macular Edema Treated With Ranibizumab (IVRDME)

Diabetic Macular Edema

China
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMD (SAFARI)

Neovascular Age-related Macular Degeneration

Germany, United Kingdom
National Eye Institute (NEI)

Completed

Ranibizumab Injections to Treat Macular Telangiectasia Without New Blood Vessel Growth

Macular Telangiectasia

United States
National Eye Institute (NEI)

Completed

Injected Ranibizumab to Treat Macular Telangiectasia Without New Blood Vessel Formation

Telangiectasia

United States
National Eye Institute (NEI)

Completed

Injected Ranibizumab to Treat Macular Telangiectasia With New Blood Vessel Formation

Telangiectasia

United States
Novartis Pharmaceuticals

Completed

A Clinical Study in Current Medical Practice of the Efficacy and Safety of Ranibizumab 0.5mg in Diabetic Patients Presenting a Visual Impairment Due to Macular Edema (LUDIC)

Macular Edema | Visual Impairment

France
University of New Mexico
Genentech, Inc.

Completed

Efficacy and Safety of Sub-tenon Ranibizumab for Recurrent Pterygia

Pterygium

United States
University Health Network, Toronto

Unknown

Geographic Atrophy and Intravitreal Ranibizumab Injections

Age-related Macular Degeneration | Geographic Atrophy

Canada
Bayer

Completed

Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA) (AURA)

Ophthalmology, Macular Degeneration

Japan, France, Germany, Australia, Italy, United Kingdom, Venezuela, Ireland, Netherlands, Canada
Oregon Health and Science University

Completed

A Study of Genetic and Environmental Factors and Their Effect on Response to Treatment With Lucentis (Ranibizumab) for Wet AMD

Macular Degeneration

United States
Shahid Beheshti University of Medical Sciences

Unknown

Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trial

Age Related Macular Degeneration

Iran, Islamic Republic of
Mayo Clinic

Completed

Intravital Microscopy in Human Solid Tumors

Malignant Solid Neoplasm | Gastric Carcinoma | Solid Tumor, Adult | Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Metastatic Gastric Carcinoma | Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8 | Metastatic Sarcoma | Resectable... and other conditions

United States
Stanford University

Completed

Study of Bimonthly VEGF Trap-Eye Compared to As-needed Administration or Other Therapy for Exudative Age-Related Macular Degeneration

Exudative Age-related Macular Degeneration

United States

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