Clinical Trials Sponsored by Diagram B.V.

Total 1654 results

Terumo Europe N.V.

Recruiting

Holmium-166 Transarterial Radioembolization in Unresectable, Early Stage Hepatocellular Carcinoma. (HOMIE-166)

Hepatocellular Carcinoma

Germany
Sequana Medical N.V.

Withdrawn

Optimal Balance Alfapump® System Feasibility Study (OPTIMALBALANCE)

Heart Failure

Hungary
Sequana Medical N.V.

Completed

ALFApump System Post Marketing Surveillance Registry (2011-AAR-004)

Liver Cirrhosis | Malignant Ascites | Refractory Ascites

Germany, Switzerland, Spain, United Kingdom
Terumo Europe N.V.

Completed

e-NOBORI Observational Registry of Nobori DES (e-NOBORI)

Coronary Artery Disease

Ireland, France, Taiwan, Spain, United Kingdom, Israel, Netherlands, Czechia, Sweden, Bangladesh, Russian Federation, Brazil, Bulgaria, Serbia, Chile, Germany, Hungary, Indonesia, Georgia, Austria, Belarus, Denmark, Egypt, Estonia, Latvia, Lithuan... and more
Terumo Europe N.V.

Unknown

Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry (e-Ultimaster)

Coronary Artery Disease

Netherlands, France, United Kingdom, Austria, Ireland, Spain, Bulgaria, South Africa, Israel, Hungary, Switzerland, Chile, Belgium, Japan, Argentina, Portugal, United Arab Emirates, Serbia, Malaysia, Brazil, India, Poland, Indonesia, ... and more
Terumo Europe N.V.

Completed

Optical Frequency Domain Imaging (OFDI) Assessed Strut Coverage of New Terumo DES (DISCOVERY123)

Coronary Artery Disease

France, Netherlands, Germany
Trod Medical N.V.

Unknown

Focal Prostate Radiofrequency Ablation (ProRAFT)

Prostate Cancer

United Kingdom
Sequana Medical N.V.

Completed

A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites (MOSAIC)

Cirrhosis | Ascites

Canada, United States
Sequana Medical N.V.

Unknown

Effects of Treatment of Ascites by the ALFApump System on Renal and Circulatory Function

Cirrhosis, Liver | Refractory Ascites

Spain
Terumo Europe N.V.

Recruiting

BioPearl™ Microspheres Loaded With Doxorubicin for the Treatment of Unresectable Hepatocellular Carcinoma (HCC) (BIOPEARL-ONE)

Hepatocellular Carcinoma Non-resectable

Belgium, Germany, Italy
Sequana Medical N.V.

Recruiting

International Alfapump Cohort Study (TOPMOST)

Liver Cirrhoses | Malignant Ascites

Germany, Switzerland
Terumo Europe N.V.

Completed

Treatment of Patients With Lesions in the Superficial Femoral and/ or Popliteal Arteries Using Kanshas Paclitaxel-coated Balloon Catheter. (KANSHAS-1)

Peripheral Artery Disease | Femoropopliteal Occlusive Disease

Belgium, Germany
Terumo Europe N.V.

Completed

Prospective Single Arm CAS - ROADSAVER Study (ROADSAVER)

Carotid Artery Stenosis

Belgium, Spain, Czechia, France, Serbia, Netherlands, Germany, Hungary, North Macedonia, Latvia, Poland, Portugal, Slovakia
Sequana Medical N.V.

Active, not recruiting

Alfapump® System in the Treatment of Refractory or Recurrent Ascites (POSEIDON Study) (POSEIDON)

Ascites

United States, Canada
Sequana Medical N.V.

Active, not recruiting

Safety & Feasibility of DSR TherApy in Heart FAiluRe pAtients With Persistent Congestion (SAHARA)

Heart Failure | Volume Overload

Georgia
Terumo Europe N.V.

Completed

Post-Market Clinical Investigation of the FemoSeal™ VCS: A Prospective, Multi-Center Observational European Study (FEMOSEAL CLOSE)

Peripheral Vascular Disease | Hemostasis | Vascular Closure | Endovascular Procedure

Belgium, France, Germany
Terumo Europe N.V.

Withdrawn

BioPearl™ Microspheres Loaded With Doxorubicin: Prospective, Single Arm, Multi-centre Post-market Follow-up Study. (BIOPEARL-FIRST)

Hepatocellular Carcinoma

Belgium
Octimet Oncology N.V.

Terminated

OMO-1 in Solid Malignancies

Neoplasms

France, United Kingdom, Netherlands, United States, Belgium
Terumo Europe N.V.

Completed

LifePearl Anthracyclin Registry in Selective Chemo-Embolization of Patients With Unresectable HCC (PARIS Registry)

Hepatocellular Carcinoma

Belgium, France
Terumo Europe N.V.

Terminated

Renal Sympathetic Denervation by Iberis System in Patients With Uncontrolled Hypertension - Iberis-HTN Registry (Iberis)

Resistant Hypertension

Serbia, Spain
Sequana Medical N.V.

Terminated

Alfapump-albumin Replacement Therapy

Liver Cirrhosis

United Kingdom
Sequana Medical N.V.

Completed

Retrospective Study in the Use of the Alfapump and the Treatment of Malignant Ascites

Malignant Ascites

Germany, Switzerland, United Kingdom
BHV Pharma
Integrium

Completed

Safety and Efficacy of Biphasic Remogliflozin Etabonate in the Treatment of Type 2 Diabetes (BRID)

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

United States
Sequana Medical N.V.

Terminated

Investigation Into the Automated Drainage of Recurrent Effusions From the Pleural Space in Thoracic Malignancy. (ADEPT)

Pleural Effusion

France, United Kingdom
Terumo Europe N.V.

Unknown

Rapid Exchange Devices Observational Registry. (RXRegistry)

Peripheral (Lowr Extremity) Arterial Disease.

Spain, Belgium
Deutsche Lungenstiftung e.V.

Terminated

Non-invasive Ventilation in Severe Chronic Obstructive Pulmonary Disease(COPD)

Chronic Obstructive Pulmonary Disease | Hypercapnia

Germany
Terumo Europe N.V.

Completed

Randomized Study to Assess the Effect of ThRombus Aspiration on Flow Area in STEMI Patients (TROFI)

Myocardial Infarction | Coronary Artery Disease | STEMI

Germany, France, Denmark, Netherlands
Aktion Bronchialkarzinom e.V.

Completed

Randomized Phase III-Study in Stage IIIb and IV Non-Small-Cell Lung Cancer. Sequential Single-Agent vs. Double-Agent vs. Triple-Agent Therapy.

Non-Small-Cell Lung Carcinoma

Germany
Radboud University Medical Center
Terumo Medical Corporation; Quirem Medical B.V.

Recruiting

Percutaneous Holmium Injection in Pancreatic Cancer (SLOTH-2a)

Pancreas Cancer

Netherlands
Vanderbilt University Medical Center
Renal Research Institute; Pharvaris Netherlands B.V.

Recruiting

Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor

Intradialytic Hypotension

United States
Janssen Vaccines & Prevention B.V.
Biomedical Advanced Research and Development Authority

Active, not recruiting

A Clinical Study to Evaluate an Experimental Universal Influenza Vaccine, INFLUENZA G1 mHA, in Healthy Adults

Influenza Prevention

United States
University Medical Center Groningen
Nedmag Industries Mining and Manufacturing B.V.

Unknown

Magnesium and Vascular Stiffness

Blood Pressure | Vascular Stiffness

Netherlands
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Astellas Pharma Europe B.V.
Veeda Clinical Research

Completed

Observational, Non-interventional, Non Comparative Real Life Data Collection of Depo-Eligard® 7.5 mg, 22.5 mg and 45 mg in Male Prostate Cancer Patients (TREMODI)

Prostate Cancer

Belgium
University Medical Center Groningen
ISA Pharmaceuticals B.V.; Dutch Cancer Society

Completed

p53 Synthetic Long Peptides Vaccine With Cyclophosphamide for Ovarian Cancer (ISA-P53-CTX)

Ovarian Cancer

Netherlands
University Medical Center Groningen
Dutch Kidney Foundation; Amphia Hospital; Healthy.io Ltd.; E-Zorg B.V. / KPN Health and other collaborators

Enrolling by invitation

Towards HOMe-based Albuminuria Screening: an Implementation Study Testing Two Approaches (THOMAS)

Albuminuria

Netherlands
Vanderbilt-Ingram Cancer Center
Medtronic

Active, not recruiting

Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration (VERITAS)

Lung Nodule

United States
UMC Utrecht
Inreda Diabetic B.V.; Dutch National Health Care Institute

Recruiting

Dual Hormone Closed Loop in Type 1 Diabetes (DARE)

Diabetes | Diabetes Mellitus, Type 1 | Diabetes type1

Netherlands
Royal Free Hospital NHS Foundation Trust
KCI Europe Holding B.V.

Terminated

Negative Pressure Wound Therapy With Instillation for Treatment of Hidradenitis Suppurativa (HIDRA)

Hidradenitis Suppurativa

United Kingdom
EsoCap AG
FGK Clinical Research GmbH; FGK Representative Service B.V.

Completed

A Study to Investigate the Efficacy and Tolerability of ESO-101 in Patients With Eosinophilic Esophagitis

Eosinophilic Esophagitis

Spain, Switzerland, Netherlands, Germany, Poland
M.D. Anderson Cancer Center
Bristol-Myers Squibb; ISA Pharmaceuticals B.V.

Completed

Nivolumab and HPV-16 Vaccination in Patients With HPV-16 Positive Incurable Solid Tumors

Solid Tumors

United States
Janssen Pharmaceutica N.V., Belgium

Recruiting

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma (MoMMent)

Relapsed/Refractory Multiple Myeloma

Germany, Italy, Belgium, Spain, Netherlands, France, United Kingdom
Janssen Pharmaceutica N.V., Belgium

Active, not recruiting

A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice (PsABIOnd)

Arthritis, Psoriatic

United Kingdom, Korea, Republic of, France, Belgium, Japan, Taiwan, Austria, Canada, Netherlands, Spain, Italy, Germany, Australia, Switzerland, Mexico, Sweden, Greece, Argentina, Colombia, Russian Federation
Wissenschaftliches Institut Bethanien e.V

Completed

Comparison of CPAP With SOMNOventCR in Patients With Underlying Heart Disease, Combined OSA and CSR (VCR)

Heart Diseases | Sleep Apnea, Obstructive | Sleep Apnea, Central
Wissenschaftliches Institut Bethanien e.V

Completed

Different Loop Gain Phenotypes in Patients With Chronic Systolic Heart Failure and Periodic Breathing

Periodic Breathing

Germany
Liquid I.V.
Lipscomb University

Completed

Efficacy of Different Oral Rehydration Solutions on the Hydration Status of Healthy Males

Fluid Retention | Beverage Hydration Index | Hydration Status

United States
Janssen Pharmaceutica N.V., Belgium

Completed

A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19

Critical Confirmed Coronavirus Disease (COVID)-19

United States
Wissenschaftliches Institut Bethanien e.V

Completed

Epidemiological Analysis of Ambulant Patients in a COVID-19 Outpatient Clinic

COVID-19

Germany
Wissenschaftliches Institut Bethanien e.V

Completed

Epidemiological Multicohort Study of Latent COVID-19 Infections

COVID-19

Germany
L.V. Prasad Eye Institute

Completed

Ologen® Collagen Matrix in Patients With Primary Congenital Glaucoma Undergoing Trabeculectomy

Primary Congenital Glaucoma | Developmental Glaucoma | Infantile Glaucoma

India

Clinical Trials Sponsored by Diagram B.V.

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