Clinical Trials Sponsored by Horizon Therapeutics, Inc.

Total 3031 results

Repros Therapeutics Inc.

Completed

Safety and Efficacy of Telapristone Acetate (Proellex®) in the Treatment of Pre-Menopausal Women With Confirmed, Symptomatic Endometriosis

Endometriosis

United States
Xalud Therapeutics, Inc.

Completed

Preliminary Evaluation of Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Osteoarthritic Pain

Osteoarthritis, Knee

Australia
Repros Therapeutics Inc.

Completed

Safety and Efficacy of Telapristone Acetate (Proellex®) Administered Vaginally for the Treatment of Uterine Fibroids

Uterine Fibroids

United States
Cara Therapeutics, Inc.

Completed

A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery

Post Abdominal Surgery Pain

United States
Lisata Therapeutics, Inc.

Terminated

Autologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic Melanoma

Stage IV Melanoma | Stage III Melanoma

United States
Avenue Therapeutics, Inc.

Active, not recruiting

Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain Abdominoplasty

Pain Management

United States
miRagen Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MRG-110 Following Intradermal Injection in Healthy Volunteers

Healthy Volunteer

United States
Repros Therapeutics Inc.

Completed

Comparison of Two Formulations of Androxal

Bioequivalence

United States
Repros Therapeutics Inc.

Completed

Crossover Study of the Safety and PK Properties of Proellex®

Pharmacokinetics

United States
Aclaris Therapeutics, Inc.

Completed

A Study of A-101 Topical Solution Administered Twice a Week in Subjects With Common Warts

Common Wart

United States
Esperion Therapeutics, Inc.

Completed

A Study of the Safety, Pharmacokinetic Drug Interaction and Efficacy of ETC-1002 and Atorvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Esperion Therapeutics, Inc.

Completed

A Multiple Ascending Dose Study of ETC-1002 in Subjects With Mild Dyslipidemia

Mild Dyslipidemia

United States
Emergo Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Norketotifen in Healthy Subjects

Healthy Subjects

United States
Obalon Therapeutics, Inc.

Completed

Pilot Study to Evaluate A Novel Gastric Space Occupying Device

Obesity

Mexico
Pearl Therapeutics, Inc.

Completed

Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD

Chronic Obstructive Pulmonary Disease

United States, Germany, United Kingdom, China, Taiwan, Korea, Republic of, Japan, Czechia, Hungary, Poland, Russian Federation
Repros Therapeutics Inc.

Terminated

Study Evaluating the Safety and Efficacy of Proellex® in the Treatment of Endometriosis-extension Study

Endometriosis

United States
Mirati Therapeutics Inc.

Completed

Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies

Advanced Cancer

United States, Korea, Republic of, Canada
Aclaris Therapeutics, Inc.

Completed

Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis

Seborrheic Keratosis

United States
G1 Therapeutics, Inc.

Completed

Safety, Pharmacokinetic and Pharmacodynamic Study of the CDK 4/6 Inhibitor G1T28-1

Healthy Volunteers

Netherlands
INSYS Therapeutics Inc

Completed

Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain

Pain, Postoperative

United States
Tacere Therapeutics, Inc.

Terminated

Long-Term Follow-Up Safety Monitoring of Patients Dosed in the First-in-Man Phase I/II Study of TT-034.

Hepatitis C

United States
Edge Therapeutics Inc

Terminated

Safety/Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With aSAH

Subarachnoid Hemorrhage, Aneurysmal

United States, Canada
INSYS Therapeutics Inc

Completed

Cannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure Disorder

Seizures

United States
NovaDigm Therapeutics, Inc.

Completed

Safety, Tolerability, Immunogenicity and Efficacy of NDV-3A Vaccine in Preventing Recurrent Vulvovaginal Candidiasis

Vulvovaginal Candidiasis

United States
Pearl Therapeutics, Inc.

Completed

PT001 MDI Versus Atrovent Study in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States
Tenax Therapeutics, Inc.

No longer available

Levosimendan Compassionate Use in Pediatric Patients With Advanced Decompensated Heart Failure

Heart Decompensation
Elcelyx Therapeutics, Inc.

Completed

Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM

Type 2 Diabetes Mellitus

United States, Puerto Rico
Biosplice Therapeutics, Inc.

Completed

A Repeat Insult Patch Test (RIPT) Study Evaluating the Sensitization Potential of Topical SM04755 Solution in Healthy Volunteers

Tendinopathy

United States
Clarus Therapeutics, Inc.

Completed

Phlebotomy Study of Testosterone Undecanoate

Hypogonadism

United States
INSYS Therapeutics Inc

Completed

Fentanyl Sublingual Spray for the Treatment of Moderate to Severe Post-Operative Pain

Pain

United States
Aclaris Therapeutics, Inc.

Completed

An Open-Label Safety Study of A-101 Solution

Seborrheic Keratosis

United States
Aclaris Therapeutics, Inc.

Completed

A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.

Seborrheic Keratosis

United States
Aclaris Therapeutics, Inc.

Completed

A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic Keratosis (SK)

Seborrheic Keratosis

United States
Pearl Therapeutics, Inc.

Completed

Study to Assess the Efficacy and Safety of Three Doses of PT001 in Japanese Subjects With Moderate to Severe COPD

Chronic Obstructive Pulmonary Disease

Japan
Repurposed Therapeutics, Inc.

Terminated

Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray

Motion Sickness

United States
Onconova Therapeutics, Inc.

Completed

Phase I Study of ON 01910.Na in Refractory Leukemia or Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Chronic Lymphocytic Leukemia | Chronic Myelocytic Leukemia | Acute Lymphocytic Leukemia | Acute Myelocytic Leukemia

United States
Tobira Therapeutics, Inc.

Completed

Pharmacokinetic and Safety Study of Cenicriviroc and HMG-CoA Reductase Inhibitors, Caffeine and Digoxin

Healthy

United States
Aciex Therapeutics, Inc.

Completed

A Multi-Center Study Evaluating the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle in the Conjunctival Allergen Challenge (CAC)

Allergic Conjunctivitis

United States
SPR Therapeutics, Inc.

Completed

Electrical Stimulation for the Treatment of Chronic Post-Stroke Shoulder Pain Using the Smartpatch System

Hemiplegic Shoulder Pain | Post-stroke Shoulder Pain

United States
Pearl Therapeutics, Inc.

Completed

PT001 MDI Versus Spiriva® in Patients With Moderate to Severe COPD

Chronic Obstructive Pulmonary Disease

United States
Melinta Therapeutics, Inc.

Completed

Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Skin and Subcutaneous Tissue Bacterial Infections

United States, Croatia, Israel, Latvia, Russian Federation, Spain, Ukraine
Aciex Therapeutics, Inc.

Completed

A Comparison of the Safety and Comfort of AC-170

Normal Ocular Health

United States
Mirati Therapeutics Inc.

Completed

Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS

Myelodysplastic Syndrome

United States
Mirati Therapeutics Inc.

Completed

Study of Mocetinostat in Patients With Urothelial Carcinoma Having Inactivating Alterations of Specific Genes

Urothelial Carcinoma

United States
INSYS Therapeutics Inc

Completed

Study of Buprenorphine Sublingual Spray for the Treatment of Moderate to Severe Pain

Pain

United States
Biosplice Therapeutics, Inc.

Completed

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of SM04755 Following Topical Administration to Healthy Subjects

Tendinopathy

United States
Onconova Therapeutics, Inc.

Completed

Efficacy and Safety of ON 01910.Na in Myelodysplastic Syndrome (MDS) Patients With Trisomy 8 or Classified as Intermediate-1, -2 or High Risk

Myelodysplastic Syndrome

United States
INSYS Therapeutics Inc

Completed

Cannabidiol Oral Solution in Pediatric Participants With Treatment-resistant Seizure Disorders

Seizures

United States
Onconova Therapeutics, Inc.

Completed

Metabolism and Excretion of [14C]-Rigosertib After Infusion to Volunteers

Healthy

United States
Onconova Therapeutics, Inc.

Completed

Platinum-based Chemoradiotherapy and Rigosertib in Head and Neck Cancer

Head and Neck Neoplasms | Carcinoma, Squamous Cell

United States

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