Search clinical trials for: Antiretroviral Treatment-Naive

Total 4561 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.

Active, not recruiting

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

Malignant Solid Neoplasm | Soft Tissue Sarcoma | Recurrent Ovarian Carcinoma | Triple Negative Breast Cancer | Recurrent Osteosarcoma | Refractory Osteosarcoma | Bone Sarcoma | Giant Cell Tumor of Bone | Ovarian Carcinosarcoma | Platinum-Resistant Ovarian Carcinoma | Dedifferentiated Chondrosarcoma | Malignancy... and other conditions

United States
University of Melbourne
Australian and New Zealand Intensive Care Research Centre; The Peter Doherty... and other collaborators

Active, not recruiting

Australasian COVID-19 Trial (ASCOT) ADAptive Platform Trial (ASCOT)

SARS-CoV-2 Infection (COVID-19)

Australia
University of Washington
Fogarty International Center of the National Institute of Health

Active, not recruiting

Two-way Texting (2wT) to Improve Antiretroviral (ART) Patient Retention in Malawi

Retention in Care

Malawi
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Active, not recruiting

More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents (MOCHA)

HIV Infections

Thailand, United States, Botswana, Uganda, South Africa
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Aerosolized Aldesleukin in Treating Patients With Lung Metastases

Sarcoma | Metastatic Melanoma | Metastatic Renal Cell Cancer | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IV Osteosarcoma AJCC v7 | Metastatic Osteosarcoma | Stage IV Renal Cell Cancer AJCC v7 | Metastatic Malignant Neoplasm in the Lung

United States
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Terminated

Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH

Human Immunodeficiency Virus

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Melanoma

Metastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7

United States
Pfizer

Completed

Relative Bioavailability Study of Nirmatrelvir/Ritonavir Oral Powder Relative to the Commercial Tablets and Estimation of the Effect of Food on Bioavailability of the Nirmatrelvir/Ritonavir Oral Powder in Healthy Participants.

Biological Availability

Belgium
Cliniques universitaires Saint-Luc- Université...

Completed

Gut Microbiota, PGx and INSTIs Response

HIV Infections

Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

FDG PET-MRI for the Diagnosis of Spinal Cord Lesions

Spinal Cord Neoplasm

United States
University of Edinburgh
Medical Research Council; NHS Lothian

Completed

Inhibition of Reverse Transcription in Aicardi-Goutières Syndrome (AGS-RTI)

Aicardi-Goutières Syndrome

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Promyelocytic Leukemia With PML-RARA

United States
University College Dublin
ViiV Healthcare; Mater Misericordiae University Hospital

Terminated

Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject Drugs (TAISTR)

Human Immunodeficiency Virus

Ireland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

T-Cell Infusion, Aldesleukin, and Utomilumab in Treating Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Carcinoma | HLA-A*0201 Positive Cells Present | COL6A3 Positive | PRAME Positive

United States
University of Washington
Bill and Melinda Gates Foundation

Completed

A Cohort for Evaluation of Open-label PrEP Use and PreP Preferences Among African Women (INSIGHT)

HIV Infections

Kenya, Malawi, South Africa, Swaziland, Uganda, Zambia, Zimbabwe
University of Guadalajara

Completed

Effect of Aerobic Training and Ginkgo Biloba on Lipids Levels in HIV-positive Patients Undergoing Antiretroviral Treatment

Human Immunodeficiency Virus

Mexico
University of California, San Francisco
Gilead Sciences; ViiV Healthcare

Active, not recruiting

Immediate Initiation of Antiretroviral Therapy During "Hyperacute" HIV Infection (DGVTAF)

HIV

United States
IrsiCaixa

Completed

Impact of Raltegravir Intensification on HIV-1-infected Subjects With Complete Viral Suppression Under Monotherapy With Protease Inhibitors

HIV-1 Infection

Spain
University of California, Berkeley
Health for a Prosperous Nation; Tanzania Ministry of Health, Community Development... and other collaborators

Active, not recruiting

Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy Phase II (Afya 2 Phase2)

HIV (Human Immunodeficiency Virus)

Tanzania
Advancing Clinical Therapeutics Globally for HIV...
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Early ART to Limit Infection and Establishment of Reservoir (EARLIER)

HIV-1 Infection

United States, Brazil, Malawi, Zimbabwe, Thailand, Peru
National Institute of Allergy and Infectious Diseases...

Completed

Study of People With HIV Infection Who Have High Viral Loads Despite Combination Antiretroviral Therapy

Human Immunodeficiency Virus | Acquired Immune Deficiency Syndrome Virus | Acquired Immunodeficiency Syndrome Virus | AIDS Virus | Human Immunodeficiency Viruses

United States
Henry M. Jackson Foundation for the Advancement...
US Military HIV Research Program; Janssen Vaccines & Prevention B.V.

Withdrawn

Safety and Efficacy of Neutralizing Antibodies and Vaccination for Induction of HIV Remission (RV582)

HIV-1-infection

Thailand
Janssen Research & Development, LLC

Completed

A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed

HIV

Italy, Thailand, Spain, Uganda, Portugal, South Africa
University of Maryland, Baltimore
ViiV Healthcare

Completed

Maraviroc Efficacy for Hepatitis C (MAVERIC)

Hepatitis C | Human Immunodeficiency Virus

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Montefiore... and other collaborators

Completed

Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma

Skin Kaposi Sarcoma | Recurrent Kaposi Sarcoma

United States, Uganda, South Africa
Pfizer

Completed

A Study of COVID-19 Patients Receiving Treatment With Nirmatrelvir; Ritonavir in the Kingdom of Saudi Arabia

Covid-19

Saudi Arabia
Rhode Island Hospital

Completed

Maraviroc in Patients With Moderate and Severe COVID-19

COVID

United States
University College, London
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Active, not recruiting

Long-Acting Treatment in Adolescents (LATA) (LATA)

HIV Infections | Hiv | HIV-1-infection | Paediatric Human Immunodeficiency Virus Infection

Uganda, Zimbabwe, Kenya, South Africa
The Crofoot Research Center, Inc.
Janssen Scientific Affairs, LLC

Completed

Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART) (ReSTART)

HIV-1-infection

United States
Beyond Batten Disease Foundation
Theranexus

Active, not recruiting

An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease

Batten Disease

United States
Whitman-Walker Institute
ViiV Healthcare

Enrolling by invitation

Clinical Effectiveness-Implementation Hybrid Type 2 Study on Home-Delivered Cabenuva for People Living With HIV Who Are Not Retained in Care (CREATE)

HIV

United States
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Completed

Pharmacokinetic Study of Cabotegravir and Rilpivirine Long-acting Intramuscular Injections in Healthy Adult Participants

HIV Infections

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Unity Health Toronto
Gilead Sciences; CIHR Canadian HIV Trials Network

Terminated

Virtual PrEP: Rendering PrEP Delivery More Efficient (VPrEP)

HIV Infections

Canada
MSD Pharmaceuticals LLC

Completed

ART First-line Treatment Durability in Russia

HIV-1-infection

Russian Federation
National Cancer Institute (NCI)

Active, not recruiting

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Ganglioneuroblastoma | High Risk Neuroblastoma

United States, New Zealand, Australia
University of Minnesota
American College of Clinical Pharmacy

Completed

Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract

HIV/AIDS | Menopause | Inflammation Vagina

United States
The Methodist Hospital Research Institute

Active, not recruiting

Study in ALS With Abatacept & IL-2

Amyotrophic Lateral Sclerosis

United States
University of Miami

Active, not recruiting

PrEP at a Syringe Services Program

Hiv | Substance Use Disorders

United States
Emory University
Centers for Disease Control and Prevention

Completed

Biomarkers for Event-driven PrEP Adherence

Human Immunodeficiency Virus

United States
CytoDyn, Inc.
Amarex Clinical Research

Completed

Double Blind, Placebo Controlled Study of Safety and Efficacy of Leronlimab in Patients With "Long" COVID-19

Coronavirus Disease 2019

United States
University of Alabama at Birmingham
University of Colorado, Denver; National Institute of Mental Health (NIMH); University... and other collaborators

Completed

Optimizing Viral Load Suppression in Kenyan Children on Antiretroviral Therapy (Opt4Kids)

Chronic HIV Infection

Kenya
University of California, Los Angeles
University of Cape Town

Active, not recruiting

Evaluation of Pre-Exposure Prophylaxis (PrEP) in Pregnant and Breastfeeding Women (PrEP-PP)

HIV-I Infection

South Africa
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Extracorporeal Photopheresis and Low Dose Aldesleukin in Treating Patients With Steroid Refractory Chronic Graft-Versus-Host Disease

Chronic Graft Versus Host Disease

United States
The First Affiliated Hospital of Zhengzhou University
Luoyang Central Hospital; Nanyang Central Hospital; The Fifth People's Hospital... and other collaborators

Completed

The Real-world Clinical Study of Azvudine Tablets in the Treatment of COVID-19

COVID-19 | Azvudine

China
Amicus Therapeutics

Active, not recruiting

First-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administered With Oral AT2221

Pompe Disease

United States, Netherlands, United Kingdom, Australia, Germany, New Zealand
Pfizer

Completed

A Study to Learn About the Medicine (PF-07321332 or Nirmatrelvir/Ritonavir) in Healthy Lactating Women

Healthy Participants

Belgium
Centre for the AIDS Programme of Research in South...
Johns Hopkins University; National Institute of Allergy and Infectious Diseases... and other collaborators

Active, not recruiting

INSTI's For The Management of HIV-associated TB (INSIGHT)

HIV/AIDS | Tuberculosis, Pulmonary

South Africa
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effect of N-803 on B Cell Follicles in Antiretroviral Treated HIV Disease

HIV Infections | Hiv | AIDS

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Auto BMT for Non-M3 AML in 1st Remission in Pts </=60y of Age Using Busulfan/FTBI & VP16 as a Prep R

Leukemia

Search clinical trials for: Antiretroviral Treatment-Naive

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