Search clinical trials for: Antiretroviral agents

Total 187734 results

Pfizer

Completed

PF-07321332/Ritonavir and Ritonavir on Dabigatran Study in Healthy Participants

Healthy Participants

United States
University of Miami

Completed

Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients

Smoking | Smoking Cessation | HIV

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Safety and Efficacy of a Switch to Doravirine/Islatravir in Participants With HIV-1 (MK-8591A-017)

HIV Infection

United States, Australia, Canada, Chile, Colombia, France, Italy, Japan, New Zealand, Poland, Russian Federation, South Africa, Spain, Switzerland, United Kingdom
Janssen Research & Development, LLC

Completed

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

France, Taiwan, Canada, United States, Germany, Spain, Japan, Russian Federation, Turkey, United Kingdom
Pfizer

Withdrawn

A Study to Learn About the Patients With COVID-19 Prescribed Paxlovid in Morocco

COVID-19 Drug Treatment
University of Oxford

Completed

Tenofovir in Pregnancy to Prevent Mother to Child Transmission of Hepatitis B. (PK-TDF)

Hepatitis B | Pregnancy | Tenofovir

Thailand
Pfizer

Completed

A Study to Learn About a Repeat 5-Day Treatment With the Study Medicines (Called Nirmatrelvir/Ritonavir) in People 12 Years Old or Older With Return of COVID-19 Symptoms and SARS-CoV-2 Positivity After Finishing Treatment With Nirmatrelvir/Ritonavir

COVID-19

United States, Taiwan, Italy, Canada, Greece
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Active, not recruiting

Genetically Modified T Cells and Decitabine in Treating Patients With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma

United States
Hospital do Coracao

Completed

Antiviral Agents Against COVID-19 Infection (REVOLUTIOn)

COVID-19

Brazil
University Health Network, Toronto

Active, not recruiting

"Re-Stimulated" TILs And IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Fallopian Tube Cancer | Primary Peritoneal Cancer | High Grade Serous Ovarian Cancer | Recurrent | Platinum-resistant

Canada
Hospital Infantil Universitario Niño Jesús, Madrid...
Universitat Autonoma de Barcelona; Instituto de Investigación Sanitaria de... and other collaborators

Completed

Lentiviral-mediated Gene Therapy of Fanconi Anemia Patients Subtype A (FANCOLEN-1)

Fanconi Anemia

Spain
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Doravirine (MK-1439) in Participants With Human Immunodeficiency Virus 1 (HIV-1) (MK-1439-018) (DRIVE-FORWARD)

HIV-1
Amicus Therapeutics

Active, not recruiting

A Study to Assess the Long-term Safety and Efficacy of ATB200/AT2221 in Adult Subjects With LOPD

Pompe Disease (Late-onset)

United States, Germany, Taiwan, Belgium, Australia, Slovenia, Spain, Netherlands, Hungary, Japan, Austria, United Kingdom, France, Argentina, Canada, Sweden, Denmark, New Zealand, Greece, Korea, Republic of, Bosnia and Herzegovina, Ita... and more
Gilead Sciences

Completed

Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment Naive, HIV-1 and Hepatitis B Co-Infected Adults (Alliance)

HIV-1/HBV Co-Infection

Spain, Taiwan, Korea, Republic of, Thailand, Hong Kong, Japan, France, Turkey, Puerto Rico, Malaysia, United States, China, Dominican Republic, Greece
Virginia Commonwealth University
National Institute of Mental Health (NIMH); Centers for Disease Control and... and other collaborators

Enrolling by invitation

Antiretroviral Improvement Among Medicaid Enrollees (AIMS)

Human Immunodeficiency Virus

United States
Brigham and Women's Hospital
Gilead Sciences; The Fenway Institute

Active, not recruiting

Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps) (PrEPSteps)

HIV Infections | Substance Use Disorders

United States
National Cancer Institute (NCI)

Suspended

A Prospective Randomized and Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

Melanoma

United States
National Institute of Allergy and Infectious Diseases...
Gilead Sciences; ViiV Healthcare

Active, not recruiting

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

HIV Infections

Brazil, United States, South Africa, Peru, Thailand, Argentina, Vietnam
National Institute of Allergy and Infectious Diseases...
Gilead Sciences

Completed

Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum

HIV Infections

Malawi, Zimbabwe, South Africa, Uganda
University of Miami

Completed

Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program

HIV Infections | Drug Use | Harm Reduction

United States
Roswell Park Cancer Institute

Active, not recruiting

Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Resistant Ovarian Carcinoma | Platinum-Sensitive Ovarian Carcinoma | Refractory Ovarian... and other conditions

United States
CytoDyn, Inc.
Amarex Clinical Research

Terminated

A Study of Acute Graft-Versus-Host Disease (GVHD) in Patients Undergoing Allogeneic Stem-Cell Transplantation (GVHD)

Graft Vs Host Disease

United States
National Cancer Institute (NCI)

Withdrawn

Non-Viral TCR Gene Therapy

Breast Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Endocrine/Neuroendocrine | Gastrointestinal/Genitourinary Cancers

United States
University Hospital, Basel, Switzerland
London School of Hygiene and Tropical Medicine; Swiss National Science Foundation and other collaborators

Active, not recruiting

Same-day Versus Rapid ART Initiation in HIV-positive Individuals Presenting With Symptoms of Tuberculosis (SaDAPT)

Human Immunodeficiency Virus (HIV) Infection

Lesotho, Malawi
International Partnership for Microbicides, Inc.

Active, not recruiting

Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008

HIV Infections

South Africa
Instituto de Investigación Hospital Universitario...

Completed

Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19

SARS-CoV-2 Infection

Spain
Janssen Research & Development, LLC

Terminated

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection (PENGUIN-2)

Hepatitis B, Chronic

Taiwan, Spain, Canada, Poland, United States, Japan
Quest Clinical Research
Gilead Sciences

Completed

Bictegravir/Emtricitabine/Tenofovir Alafenide Plus Doravirine

HIV-1-infection

United States
Chelsea and Westminster NHS Foundation Trust

Completed

The Effect of Dolutegravir on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers (DTG Clamp)

HIV-1-infection on Healthy Volunteers

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus Infection (INSIGHT)

Hepatitis B

France, United States, Belgium, United Kingdom, Poland, New Zealand, Germany, Italy, Canada
Harlan M Krumholz
Pfizer

Active, not recruiting

A Decentralized, Randomized Phase 2 Efficacy and Safety Study of Nirmatrelvir/Ritonavir in Adults With Long COVID. (PAXLC)

Long COVID

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Switch to Doravirine/Islatravir (DOR/ISL) in Human Immunodeficiency Virus 1 (HIV-1) Participants Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-018)

HIV Infection

United States, Australia, Austria, Canada, Finland, France, Germany, Italy, Japan, Puerto Rico, Spain
University of Minnesota
National Health and Medical Research Council, Australia; Bristol-Myers Squibb; National Institutes of Health Clinical Center (CC) and other collaborators

Completed

Strategic Timing of Antiretroviral Treatment (START)

HIV Infection

Spain, United States, United Kingdom, Ireland, Australia, Argentina, Denmark, Sweden, Israel, Switzerland, Germany, Brazil, Norway, Chile, Thailand, Peru, Portugal, Greece, Luxembourg, Uganda, Austria, Belgium, Czechia, Estonia, Finland, ... and more
Gilead Sciences

Active, not recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed Children

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Uganda, South Africa, Zimbabwe
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Active, not recruiting

SEARCH CAB LA Dynamic Choice HIV Prevention Study Extension

HIV

Kenya, Uganda
Boston University
National Institute of Mental Health (NIMH)

Completed

Integrating U=U Into HIV Counseling in South Africa (INTUIT-SA)

HIV

South Africa
Dana-Farber Cancer Institute
The Leukemia and Lymphoma Society

Active, not recruiting

CIML NK Cells With Venetoclax for AML

Acute Myeloid Leukemia | Leukemia | Leukemia, Myeloid | Acute Myeloid Leukemia Recurrent

United States
Vanderbilt University Medical Center
AbbVie

Completed

Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19 (TREATNOW)

COVID-19

United States
Massachusetts General Hospital
Novartis; Genentech, Inc.

Completed

Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy (ACTIVATE)

HIV Infection

United States
The HIV Netherlands Australia Thailand Research...
Khon Kaen University

Active, not recruiting

A Prospective Cohort of Children With HIV Infection

HIV Infections

Thailand
Immatics US, Inc.
M.D. Anderson Cancer Center

Completed

ACTolog in Patients With Solid Cancers (ACTolog)

Cancer | Solid Tumor

United States
Peking University People's Hospital

Completed

Low-dose Recombinant Human IL-2 for the Treatment of Relapsing Polychondritis

Relapsing Polychondritis

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Genzyme, a Sanofi Company; American Association...

Completed

Plerixafor and Cemiplimab in Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

United States
Centre Hospitalier Universitaire Dijon

Completed

Optimization of HIV-1 DNA Genotyping by High Throughput Sequencing to Document Antiretroviral Resistant Mutations (Mutapro)

HIV-1-infection

France
Merck Sharp & Dohme LLC

Completed

Effects of Switching From ATRIPLA™ (Efavirenz, Tenofovir, Emtricitabine) to MK-1439A (Doravirine, Tenofovir, Lamivudine) in Virologically-Suppressed Participants (MK-1439A-028)

HIV-1 | Central Nervous System
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC; Prometheus Laboratories

Active, not recruiting

Interleukin-2 and Pembrolizumab for Metastatic Kidney Cancer

Kidney Cancer

United States
University of Washington
University of Colorado, Denver; Gilead Sciences; Kenya Medical Research Institute

Completed

The Women TAF-FTC Benchmark Study

HIV Infections

Kenya
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Completed

A Phase IIb Study to Evaluate a Long-Acting Intramuscular Regimen for Maintenance of Virologic Suppression (Following Induction With an Oral Regimen of GSK1265744 and Abacavir/Lamivudine) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected, Antiretroviral Therapy-Naive Adult Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

Germany, Spain, France, United States, Canada
Fundacion IDEAA
ViiV Healthcare

Completed

Efficacy of Dolutegravir Plus Lamivudine in HIV-1-infected Treatment-naïve Adults Without a Baseline Genotyping Test (D2ARLING)

Hiv | HIV-1-infection

Argentina

Search clinical trials for: Antiretroviral agents

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