Search clinical trials for: Controlled Human Exposure Study

Total 145240 results

GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
HealthPartners Institute

Recruiting

Hepatitis C Lab Testing Comparison Study

Hepatitis C

United States
University Hospitals Cleveland Medical Center

Not yet recruiting

eHealth for Breastfeeding Support - the HOTSPOT Trial

Breast Feeding

United States
B.Braun Avitum AG

Recruiting

Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis

Renal Dialysis

Italy
King Chulalongkorn Memorial Hospital
Health Systems Research Institute,Thailand

Recruiting

Investigating Neurocognitive Disorders Epidemiology (INDE)

Dementia | Alzheimer Disease | Cognitive Decline

Thailand
Memorial Sloan Kettering Cancer Center
Hookipa Biotech GmbH; Naveris

Recruiting

A Study of HB-202/HB-201 in People With Human Papilloma Virus 16-Positive Head and Neck Squamous Cell Cancer (HPV 16+ HNSCC)

HPV16+ Squamous Cell Carcinoma

United States
Temple University

Not yet recruiting

Peer Facilitated Waitlist Controlled Transportation Study

Serious Mental Illness
Wageningen University

Recruiting

The EXPLAIN Study: Exploring Plant-Based Meat Analogues for Their Impact on Health (EXPLAIN)

Blood Pressure | Cardiometabolic Health

Netherlands
bioLytical Laboratories

Not yet recruiting

A Study to Evaluate the Performance, Usability, and Result Interpretation of INSTI® HIV Self-Test

Human Immunodeficiency Virus I Infection | Human Immunodeficiency Virus II Infection
Children's Oncology Group

Not yet recruiting

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Central Nervous System Germinoma | Diabetes Insipidus | Pineal Region Germinoma | Suprasellar Germinoma
bioLytical Laboratories
St Vincent's Hospital Melbourne

Not yet recruiting

A Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Sites

Hepatitis B | Hepatitis B Infection

Australia
Versa Vascular, Inc

Not yet recruiting

A First in Human Study for the Versa Device for Tricuspid Regurgitation

Tricuspid Regurgitation

New Zealand
Puma Biotechnology, Inc.

Not yet recruiting

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer (ALISCA-Breast1)

Metastatic Breast Cancer | Recurrent Breast Cancer | Hormone Receptor Positive HER-2 Negative Breast Cancer

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

An Phase III Study, Multicenter，Randomized Controlled Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma.

Bladder Cancer

China
Chinese University of Hong Kong

Recruiting

SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus

Chronic Hepatitis B

Hong Kong
Centre Hospitalier Universitaire de la Réunion

Not yet recruiting

Psychotrauma Prevention Algorithm : Randomized, Controlled Pilot Study (A2P)

Psychological Trauma
Wake Forest University Health Sciences
InnoTech Precision Medicine

Not yet recruiting

Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer

Oropharyngeal Squamous Cell Carcinoma | Human Papillomavirus Infection

United States
Octapharma

Recruiting

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Acute Hereditary Angio Edema

Romania
Sengkang General Hospital
Singapore General Hospital; Duke-NUS Graduate Medical School; Lee Kong Chian...

Recruiting

Pilot Study of the Human Metagenome in Metabolic Diseases

Obesity | Metabolic Syndrome | Sarcopenia | Chronic Inflammation | Sarcopenic Obesity

Singapore
Icahn School of Medicine at Mount Sinai

Recruiting

A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1

Mild Cognitive Impairment | Alzheimer's Disease

United States
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Pavol Jozef Safarik University
University of Roma La Sapienza; Western University; L Pasteur University Hospital and other collaborators

Not yet recruiting

Complex Exploratory Study of Alcohol-Associated Hepatitis (CESAH)

Alcoholic Hepatitis

Slovakia
Sun Yat-sen University

Not yet recruiting

Artificial Intelligence-supported Reading Versus Standard Double Reading for the Interpretation of Magnetic Resonance Imaging in the Detection of Local Recurrence for Nasopharyngeal Carcinoma: a Randomised Controlled Multicenter Study

Artificial Intelligence Supported Image Reviewing

China
Case Comprehensive Cancer Center
National Institutes of Health (NIH); National Institute of Environmental Health...

Not yet recruiting

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Somatic Mutation
Beijing Friendship Hospital

Not yet recruiting

A Study on Factors of Biochemical Response in Autoimmune Hepatitis

Autoimmune Hepatitis

China
Divoluci

Not yet recruiting

Study Human Digital Support Transitional Care (SUNH-ST)

Aging

France
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study for Assessing the Efficacy and Safety ParActin® in Individuals With Upper Respiratory Tract Infections

Upper Respiratory Tract Infections

India
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
Vaxine Pty Ltd
Australian Respiratory and Sleep Medicine Institute Ltd

Not yet recruiting

Covid-19 and Influenza Oral Vaccine Study

Influenza, Human | covid19 Infection

Australia
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Megalabs
Azidus Laboratories

Not yet recruiting

Comparative Study of Two Recombinant Human Erythropoietin Products on Chronic Kidney Disease Patients (ENCASE)

Anemia of Chronic Kidney Disease

Uruguay
The Mediterranean Institute for the Advance of...

Not yet recruiting

The PredictPlusPrevent Study

Depression | Anxiety Disorders
Sohag University

Recruiting

The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study

Nasolacrimal Duct Obstruction

Egypt
AstraZeneca

Recruiting

A Positron-emission Tomography Study to Determine Brain Exposure of [11C]Savolitinib in Healthy Volunteers

Healthy Volunteers

Sweden
Yale University
Department of Health and Human Services

Not yet recruiting

Project Women's Insomnia Sleep Health Equity Study (WISHES) (Project WISHES)

Insomnia | Cardiometabolic Health | Sleep Health

United States
Portal Therapeutics, Inc.

Not yet recruiting

Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of PORT-77 Administered to Healthy Adult Participants

Healthy Adult Participants

United States
University of Minnesota

Not yet recruiting

Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study

Hemorrhage | Hemophilia | Facelift Surgery
Hyalex Orthopaedics, Inc.

Recruiting

The Hyalex First-in-Human Study

Cartilage Injury

Poland
Bayer

Not yet recruiting

A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer

Hepatocellular Carcinoma (HCC)

United States
Dosentrx Ltd.

Not yet recruiting

Open Label, Controlled, Post Marketing, Registry Study of Ribociclib (Ribo) Treatment Adherence and Patient Reported Outcomes in Participants Using ReX Technology Platform

Any Solid Oral Medication

United States
NeuShen Therapeutics

Recruiting

First-into-human Study of NS-136 in Healthy Subjects

Healthy Subjects

Australia
IRCCS San Raffaele
Istituto Auxologico Italiano; Fondazione Policlinico Universitario Campus Bio-Medico

Recruiting

Cellular, Molecular and Clinical Determinants of Bone Strength in in Vivo and Human Models of GH Excess. Cross-sectional and Prospective Study

Acromegaly | Bone Fracture

Italy
Synergia Medical

Not yet recruiting

A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl (AURORA)

Drug Resistant Epilepsy
European Institute of Oncology

Recruiting

Study Evaluating Occupational Exposure to Antineoplastic Drugs (BRIC)

Cytotoxicity

Italy
IRCCS Multimedica

Recruiting

FAiling HearT in the Elderly (FATE) Study (FATE)

Heart Failure | Frailty

Italy
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Tegoprazan Dual Therapy and Furazolidone-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication: A Prospective, Multicenter, Open-label, Randomized Controlled Clinical Study

Helicobacter Pylori Infection | Tegoprazan | Furazolidone
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Healthy

Germany
Centre Hospitalier Intercommunal Creteil

Not yet recruiting

Real World Environmental Exposure Study With Healthy and Cystic Fibrosis Subjects (ExpoCF)

Environmental Exposure | Cystic Fibrosis, Pulmonary | Exhaled Breath Condansate
Guangdong Ruishun Biotech Co., Ltd
Changhai Hospital; Peking University People's Hospital; RenJi Hospital; The Affiliated...

Not yet recruiting

A Study of RJMty19 in Refractory Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

China
BioNTech SE
DualityBio Inc.

Not yet recruiting

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Endometrial Cancer

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