Search clinical trials for: Cytosine methylation

Total 847 results

M.D. Anderson Cancer Center

Completed

Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies

Lymphoma | Leukemia

United States
Roswell Park Cancer Institute
Celgene Corporation

Completed

Lenalidomide and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States
M.D. Anderson Cancer Center
Ortho Biotech, Inc.

Completed

Efficacy of the HCVIDDOXIL Regimen in Patients With Newly Diagnosed Peripheral T-Cell Lymphoma

Lymphoma

United States
University of Bologna

Completed

DNA Methylation and Perioperative Pain Treatment (MEDAPO)

Pain, Postoperative | Hyperalgesia

Italy
Karolinska Institutet

Terminated

Goal Directed Haemodynamic Treatment for Patients With Proximal Femoral Fracture (GDHT)

Femoral Fracture

Sweden
Changhai Hospital

Unknown

Colorectal Cancer Screening Using Stool DNA-based SDC2 and SFRP2 Methylation Test in China

Colorectal Cancer | Adenoma | Colorectal Neoplasm | Adenomatous Polyps | Serrated Polyp | Advanced Adenoma
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With High-Risk Lymphoid Malignancies

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent Mantle Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory T-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Refractory Mantle Cell Lymphoma

United States
Jonsson Comprehensive Cancer Center

Withdrawn

Temozolomide in Treating Patients With Invasive Pituitary Tumors

Brain and Central Nervous System Tumors
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

DNA Analysis of Tumor Tissue From Patients With Acute Myeloid Leukemia

Leukemia
Masonic Cancer Center, University of Minnesota

Completed

Autologous Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma

Lymphoma

United States
Xijing Hospital

Unknown

MD2, Cystatin C and DNA Methylation Tags as Serum Biomarkers for POCD. (BM-POCD)

Postoperative Cognitive Dysfunction

China
Peking University People's Hospital

Unknown

Monitoring of Circulating Tumor DNA and Its Aberrant Methylation in the Surveillance of Surgical Lung Cancer Patients (MEDAL, MEthylation Based Dynamic Analysis for Lung Cancer). (MEDAL)

Carcinoma | NSCLC | Lung Cancer | Lung Neoplasm

China
Medical University of Vienna

Unknown

CTA Expression/Methylation and Response to Pembrolizumab of NSCLC Patients

Non Small Cell Lung Cancer

Austria
Shanghai Chest Hospital

Unknown

cfDNA Methylation Assay for Clinical Evaluation of Patients With Stage IA Lung Cancer After Ablation Operation

Lung Cancer

China
M.D. Anderson Cancer Center
Genentech, Inc.

Completed

Study of Rituximab-HCVAD Alternating With Rituximab-Methotrexate-Cytarabine Versus Standard Rituximab-CHOP Every 21 Days for Patients With Newly Diagnosed High Risk Aggressive B-Cell Non-Hodgkin's Lymphomas in Patients 60 Years Old or Younger

Lymphoma

United States
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Istanbul University

Unknown

Epigenetic Tools as Prognostic Predictors in Covid19

Prognosis

Turkey
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia

United States
St. Jude Children's Research Hospital
Karyopharm Therapeutics Inc

Terminated

Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Azacitidine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With High-Risk Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation (M1) | Adult Acute... and other conditions

United States
Massachusetts General Hospital
Takeda

Completed

Phase II Trial of Alisertib With Induction Chemotherapy in High-risk AML

Acute Myeloid Leukemia

United States
University of Copenhagen
University of Aarhus; Arla Foods; Arla Foods Ingredients

Completed

Effects of Milk Protein and Vitamin D on Children's Growth and Health (D-pro)

Appetite Regulation | Muscle Function | Cardiometabolic Health | Bone Health

Denmark
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Completed

Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States, Canada, Australia, New Zealand, Puerto Rico
PETHEMA Foundation

Completed

Treatment of High Risk Adult Acute Lymphoblastic Leukemia (LAL-AR/2003)

Acute Lymphoblastic Leukemia

Spain
The First Affiliated Hospital of Guangzhou Medical...
The First Affiliated Hospital with Nanjing Medical University; Xiangya Hospital... and other collaborators

Completed

Circulating Tumor DNA Methylation Test to Differentiate Benign and Malignant Pulmonary Nodules

Pulmonary Nodule, Solitary

China
St. Jude Children's Research Hospital
Karyopharm Therapeutics Inc

Completed

Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Mixed Phenotype Acute Leukemia (MPAL)

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Non-Hodgkin Lymphoma | B-Cell Non-Hodgkin Lymphoma | Adult Diffuse Large B-Cell Lymphoma | T-Cell Non-Hodgkin Lymphoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent High Risk Myelodysplastic Syndrome | Refractory High Risk Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States
Washington University School of Medicine
Karyopharm Therapeutics Inc

Completed

Study of CLAG + Selinexor in Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
WEIDONG LIU，MD
Natural Science Foundation of Hunan Province

Unknown

Analysis of Intestinal Microflora Combined With DNA Methylation in Stool to Detect Colorectal Cancer (IMMDC)

Colorectal Neoplasms | Gastrointestinal Microbiome | DNA Methylation

China
National Cancer Institute (NCI)

Completed

Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers

Physical Activity | Body Composition | Puberty | Methylation

China
Northwestern University

Completed

Examining the Effects of Juice Fasting

Epigenetics | Microbiome

United States
National Cancer Institute (NCI)

Completed

Discovery and Validation of Plasma DNA Methylation Biomarker for Detection of Stomach Cancer

Stomach Cancer | Gastric Cancer

United States
M.D. Anderson Cancer Center

Completed

Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome

Leukemia

United States
Lawson Health Research Institute

Completed

A New Anticoagulation Method Using Dalteparin in Quotidian and Nocturnal Home Hemodialysis Patients

Kidney Failure

Canada
AstraZeneca

Completed

Study to Investigate the Efficacy, Safety and Tolerability of AZD1152 Alone and in Combination With Low Dose Cytosine Arabinoside (LDAC)in Acute Myeloid Leukaemia (AML) Patients (SPARK-AML1)

Acute Myeloid Leukemia

United States, Italy, United Kingdom, Romania, Japan, Australia, Germany, Spain, France
Therapeutic Advances in Childhood Leukemia Consortium
Genzyme, a Sanofi Company

Terminated

T2007-002 Clofarabine, Etoposide, Cyclophosphamide in Relapsed Acute Myelogenous Leukemia (AML)

Relapsed Acute Myelogenous Leukemia

United States
Sixth Affiliated Hospital, Sun Yat-sen University
Changhai Hospital; Peking University People's Hospital; Peking University Cancer... and other collaborators

Unknown

Stool-based SDC2 DNA Methylation Test for the Detection of Colorectal Advanced Adenomatous Polyps and Cancer

Colorectal Cancer | Colorectal Adenomatous Polyp | Screening

China
Brown University
University of California, San Diego; Milton S. Hershey Medical Center; University... and other collaborators

Completed

PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation

Glioblastoma Multiforme

United States
University of North Carolina, Chapel Hill
National Institute of Dental and Craniofacial Research (NIDCR); National Center...

Completed

Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics

Smoking | Diabetes

United States
Peking University People's Hospital

Unknown

Multiplex Analysis of Circulating Tumor DNA

Carcinoma | Non-small-cell Lung Cancer | Lung Neoplasm

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

CAR.CD19-CD28-zeta-2A-iCasp9-IL15-Transduced Cord Blood NK Cells, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Participants With B-cell Lymphoma

Mantle Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | CD19 Positive

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma

Refractory Hodgkin Lymphoma | Recurrent Adult Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | T-Cell Chronic Lymphocytic Leukemia | Recurrent Childhood Non-Hodgkin... and other conditions

United States, Germany
Astex Pharmaceuticals, Inc.
Eisai Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
Assiut University

Unknown

Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C

Hepatocellular Carcinoma
Academic and Community Cancer Research United
Mayo Clinic

Completed

Trial of Oxaliplatin, Cytosine Arabinoside, Dexamethasone With Rituxan (ROAD) in Patients With Relapsed Non-Hodgkins Lymphoma

Lymphoma

United States
Ronald Levy
National Institutes of Health (NIH)

Completed

Phase 1-2 of a CpG-Activated Whole Cell Vaccine Followed by Autologous Immunotransplant for MCL

Lymphoma, Mantle-Cell

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | de Novo Myelodysplastic Syndrome | Acute Biphenotypic Leukemia

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

The Effect of Leukocyte Dna mEthylation and micRoBIOME Diversity on Host Defense Mechanisms During Community-acquired Pneumonia (ELDER-BIOME) (ELDER-BIOME)

Pneumonia

Netherlands
Peking Union Medical College Hospital

Unknown

cfDNA in Diagnosis and Differential Diagnosis of Ovarian Endometriosis

Circulating Free DNA

China

Search clinical trials for: Cytosine methylation

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