Search clinical trials for: Mechanism of change

Total 432618 results

Janelle Vaughns

Completed

Dexmedetomidine to Treat Bariatric Surgery-associated Pain

Obesity

United States
University Ghent

Completed

Identifying the Effect and Working Mechanisms of MyPlan 2.0 in Older Adults

Overweight

Belgium
University Ghent

Completed

Identifying the Effect and Working Mechanisms of MyPlan 2.0 in Adults With Type 2 Diabetes

Chronic Disease

Belgium
University Ghent

Completed

Study on Mechanisms of Changes in Liver Disease and Sex Steroid Metabolism During Weight Loss (SMELSS)

Obesity

Belgium
Hospital Clinic of Barcelona

Completed

Risk Factors for AD-Associated Switch to Mania

Bipolar Disorder

Spain
Medical University of Warsaw

Completed

Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Laparoscopic Nephrectomy/Nephron Sparing Surgery (NSS)/Hynes-Anderson Procedures.

Erector Spinae Plane Block

Poland
Riyadh Elm University

Completed

A Novel Approach in Reducing Dental Pain and Anxiety of Pediatric Patient During Local Anesthesia.

Pain | Anxiety

Saudi Arabia
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil (OM) on QT/QTc Intervals in Healthy Adults

QT Intervals Changes | QTc Intervals Changes

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and Children

HIV Infections

United States, Brazil, South Africa
Temple University

Completed

Experimental Changes in Children's Sleep Duration and Timing: Effect on Obesity and Type 2 Diabetes Risk

Sleep | Type2 Diabetes

United States
Thomas Jefferson University
AstraZeneca

Active, not recruiting

Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences

Recurrent Breast Carcinoma | Metastatic Malignant Neoplasm in the Chest Wall

United States
Rush University Medical Center
ElMindA Ltd; Takeda Pharmaceuticals North America, Inc.

Completed

The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder

Major Depressive Disorder

United States
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Evaluating Change in Drinking Identity as a Mechanism for Reducing Hazardous Drinking - Study 2

Identity, Social | Drinking; Excess, Habit (Continual)

United States
University of Saskatchewan

Completed

Tiotropium Efficacy Against Allergen Induced Early Asthmatic Responses

Allergic Asthma

Canada
University of Southern California

Completed

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

Substance Use | Alcohol Use, Underage | Alcohol Problem Drinking

United States
Karolinska Institutet
Harvard Medical School (HMS and HSDM)

Completed

Real-World Emulation of the SWEFOT Trial (SWEFOT-RWEM)

Rheumatoid Arthritis

Sweden
Federico II University

Completed

Study of Retinal and Choriocapillary Vascular Changes in Patients Undergoing Tadalafil 20mg

Erectile Dysfunction Following Radical Prostatectomy

Italy
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Investigating Fear Of Recurrence as a Modifiable Mechanism of Behavior Change (INFORM)

Medication Adherence | Acute Coronary Syndrome | Fear

United States
Sohag University

Completed

Evaluation of Lacrimal Punctal Changes by Anterior Segment Optical Coherence Tomography AS-OCT After Topical Combined Antibiotics and Steroids Treatment in Cases of Inflammatory Punctual Stenosis

Ophthalmopathy , Lacrimal System

Egypt
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Efficacy and Changes in Induced Sputum and Blood Biomarkers Following Daily Repeat Doses of Inhaled GSK2269557 in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Acute Exacerbation

Pulmonary Disease, Chronic Obstructive

Canada, Denmark
Jinling Hospital, China

Completed

Effects of Intranasal Nerve Growth Factor for Acute Ischemic Stroke

Acute Ischemic Stroke

China
University of Minnesota

Completed

Changes in Biomarkers Associated With Use of Electronic Cigarettes

Biomarkers

United States
University of Abuja
Micronova Pharmaceuticals Ind Ltd

Completed

To Determine the Effect of Nebivolol on Office Blood Pressure of Blacks Residing in Nigeria (Nevibolol)

Hypertension

Nigeria
British University In Egypt

Completed

Effect of Local Application of Platelet-rich Fibrin Scaffold Loaded With Simvastatin on Peri-implant Bone Changes

Platelet-rich Fibrin | Simvastatin

Egypt
University Hospital, Strasbourg, France

Completed

Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis (ROC)

Rheumatoid Arthritis

France, Monaco
Institute of Mental Health, Singapore

Completed

Aripiprazole as an Adjunct to Atypical Antipsychotics for Weight Reduction and Improvement in Metabolic Profile

Antipsychotics Weight Gain

Singapore
Heidelberg University
PD Dr. Henrik Watz, Pulmonary Research Center, LungenClinic Großhansdorf... and other collaborators

Active, not recruiting

Change in Airway Peripheral Tone in COPD (CAPTO-COPD)

COPD | COPD, Early-Onset

Germany
Sheffield Hallam University
King's College London; Heart Research U.K.; Help2Change

Completed

E-cigarettes and Cardiovascular Function (ISME-NRT)

Cardiovascular Diseases | Smoking Cessation | Microcirculation | Macrocirculation

United Kingdom
Dongfang Hospital Beijing University of Chinese...
First Affiliated Hospital Xi'an Jiaotong University; Xuanwu Hospital, Beijing

Unknown

The Study of Mechanism of Chronic Insomnia Disorder Using Acupuncture Based on Changes of Brain GABA and fMRI

Insomnia Disorder

China
Zonguldak Bulent Ecevit University

Completed

Changes in Cerebral Oxygenation and Cognitive Functions

Cognitive Dysfunction | Hypotension; Controlled

Turkey
Instituto Nacional de Rehabilitacion

Enrolling by invitation

Low-dose Hydroxychloroquine and Bromhexine: a Novel Regimen for COVID-19 Prophylaxis in Healthcare Professionals (ELEVATE)

Enzyme Inhibitors | Hydroxychloroquine | Antimalarials | Antirheumatic Agents

Mexico
University of California, San Francisco

Completed

Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury (BFF)

Ischemic Stroke | Fever | Traumatic Brain Injury | Subarachnoid Hemorrhage | Intracerebral Hemorrhage | Subdural Hematoma

United States
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

The Qure Study: Q-fever Fatigue Syndrome - Response to Treatment (Qure)

Fatigue Syndrome, Chronic | Q Fever | Coxiella Infection

Netherlands
The University of Texas Health Science Center at...

Completed

Treatment of Spinal Cord Injury Patients for Neurogenic Bladder: Anticholinergic Agent vs. Mirabegron (SCIMYR)

Cognitive Change | Spinal Cord Injuries | Neurogenic Bladder

United States
University of Alabama at Birmingham

Terminated

Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section

Post Surgical Pain

United States
M.D. Anderson Cancer Center

Completed

Laparoscopic Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) for Metastatic Gastric Cancer

Gastrointestinal Cancer

United States
James J. Peters Veterans Affairs Medical Center
The Craig H. Neilsen Foundation

Active, not recruiting

Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia

Hypothermia | Mild Cognitive Impairment | Tetraplegia

United States
Mayo Clinic
National Institute on Drug Abuse (NIDA)

Terminated

Addressing Post Cessation Weight Gain

Smoking Cessation | Obesity

United States
Shire

Completed

Effect of Anagrelide Hydrochloride on Any Changes in Heart Function in Healthy Volunteers

Healthy

France
Region Skane
University of Colorado, Denver; Karolinska Institutet; Lund University; The Swedish... and other collaborators

Completed

Fentanyl and Clonidine for Analgesia During Hypothermia in Term Asphyxiated Infants (SANNI 1)

Asphyxia Neonatorum

Sweden
University of Pennsylvania

Terminated

Serial [18F]Thymidine (FLT)PET/CT as a Biomarker of Response in Pemetrexed Therapy for Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer | Starting Pemetrexed Based Therapy | Unresectable Cancer

United States
Imperial College Healthcare NHS Trust

Completed

Tacrolimus Versus Prednisolone for the Treatment of Minimal Change Disease (MinTAC)

Minimal Change Disease

United Kingdom
Dow University of Health Sciences

Completed

Effect of Smoking Cessation on Tuberculosis Treatment Outcomes

Tuberculosis, Pulmonary

Pakistan
Drexel University

Completed

Evaluating Mechanisms of Action of Adaptive Goal-Setting for Physical Activity

Motivation | Mobile Health | Behavior Change | Physical Activity Promotion

United States
University of the Philippines

Completed

Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical Study

Retinopathy of Prematurity
AbbVie

Withdrawn

A Study of Oral Upadacitinib Tablets to Assess Change in Disease State in Participants Aged 12-75 Years With Moderate to Severe Atopic Dermatitis in Brazil

Atopic Dermatitis (AD)
Charite University, Berlin, Germany
Boehringer Ingelheim

Completed

Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine

Emotions

Germany
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Study Evaluating The Safety, Tolerability, And Efficacy Of Switching From Quetiapine To Ziprasidone

Schizophrenia | Schizoaffective Disorder

United States, Germany, Spain, Greece, Brazil, Turkey
Seoul National University Hospital

Completed

A Clinical Study to Assess the Effect of Change of Bile Acid on the PD and Safety of Metformin and Microbiome Profiles

Human Microbiome

Korea, Republic of
Pamukkale University

Completed

Comparison of the Efficacy of Intravenous Paracetamol and Ibuprofen in the Treatment of Fever Due to Upper Respiratory Tract Infection

Fever

Turkey

Search clinical trials for: Mechanism of change

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