Search clinical trials for: Pharmacokinetics of digoxin

Total 431391 results

Everest Medicines (China) Co.,Ltd.

Recruiting

Evaluate The Efficacy, Safety, Pharmacokinetics And Pharmacodynamics Of EVER001

Primary Membranous Nephropathy

China
Amgen

Recruiting

Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States, Korea, Republic of, Spain, Australia, Germany, France, Japan, Canada
Cluj Municipal Clinical Hospital
Iuliu Hatieganu University of Medicine and Pharmacy

Recruiting

Pharmacokinetics and Pharmacodynamics of Linezolid Continuous and Intermittent Administration

Critical Illness | Pharmacokinetics | Efficacy | Side-effect of Antibiotic | Intensive Care Unit ICU

Romania
Genentech, Inc.

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

Metastatic Prostate Cancer | Advanced Prostate Cancer

Korea, Republic of, United States, Australia
Neuramedy Co. Ltd.
Quotient Sciences

Not yet recruiting

Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101

Parkinson Disease

United Kingdom
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation (Krascendo 170)

Non-Small Cell Lung Cancer

Korea, Republic of, United States, Australia, Brazil, China, United Kingdom, Israel, Belgium, Netherlands, Argentina, Spain, Taiwan, Canada, Italy, Poland, Turkey, Sweden, Switzerland
Jiangsu Simcere Pharmaceutical Co., Ltd.
Shanghai Xianxiang Medical Technology Co., Ltd.; Simcere Zaiming

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0237 in Adult Participants With Advanced Solid Tumors

Locally Advanced Unresectable or Metastatic Solid Tumor

United States, China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Phase I Clinical Study of the Safety， Tolerability，Pharmacokinetics, and Initial Efficacy of HRS-6209 Monotherapy in Patients With Advanced Solid Tumors

Advanced Solid Tumors
MediBeacon

Recruiting

Study of MB-102 (Relmapirazin) and the Use of the MediBeacon® Transdermal GFR Measurement System Using the TGFR Reusable Sensor With Disposable Adhesive Ring

Kidney Diseases | Kidney Injury | Kidney Failure

United States
ReAlta Life Sciences, Inc.
Premier Research Group plc

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia (STAR)

Hypoxic-Ischemic Encephalopathy

United States
Chongqing University Cancer Hospital
Fundamenta Therapeutics, Ltd.

Not yet recruiting

Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Refractory or Relapsed B Cell Lymphoma

Refractory or Relapsed B Cell Lymphoma

China
Beijing Children's Hospital
Shandong University

Recruiting

Population Pharmacokinetics of Fluconazole in the Treatment of Neonatal Fungal Infectious Disease

Pharmacokinetics | Infection | Newborn | Fluconazole

China
Ascentage Pharma Group Inc.

Recruiting

A Study to Investigate the Safety, Pharmacokinetics and Efficacy of APG-5918 in Healthy Subjects or Anemic Patients

Anemia

China
Hoffmann-La Roche

Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Korea, Republic of, United States, Thailand, Hong Kong, Spain, New Zealand, Bulgaria, Taiwan, France
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

Toxicokinetics of Protein-bound Uremic Toxins in ESRD Patients

Pharmacokinetics | Renal Dialysis | Uremic; Toxemia

China
McGill University Health Centre/Research Institute...

Not yet recruiting

Ropivacaine Pharmacokinetics After Erector Spinae Block (PK)

Pain | Spinal Fusion
DeuterOncology

Recruiting

Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours

Adult Solid Tumor | Lung Cancer | Advanced Solid Tumor | Non-small Cell Lung Cancer | Non-small Cell Carcinoma | Refractory Tumor | Hereditary Renal Papillary Cancer

France, Belgium, Netherlands
AstraZeneca

Recruiting

Pharmacokinetics of Mitiperstat in Participants With Hepatic Impairment

Hepatic Impairment

United States
Peking University Third Hospital

Recruiting

A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment Patients

Chronic Kidney Disease

China
Maastricht University Medical Center

Recruiting

Improving Osimertinib Exposure and Cost-effectiveness Using Pharmacokinetic Boosting With Cobicistat (OSIBOOST-2)

Non-small Cell Lung Cancer

Netherlands
McMaster University
Center for Medicinal Cannabis Research

Recruiting

The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol (POT-GFR-PK)

Chronic Kidney Diseases | Cannabis | Dialysis

Canada
Hospices Civils de Lyon

Recruiting

Thymoglobulin® Pharmacokinetics in Patients Undergoing Hematopoietic Stem Cell Transplantation (PHASAL-GA)

Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy

France
Boehringer Ingelheim

Recruiting

A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

Liver Cirrhosis

Germany
Arisan Therapeutics, Inc.
United States Department of Defense; Battelle Memorial Institute; The Defense...

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral ARN-75039 in Healthy Adult Subjects

Lassa Virus Infection

United States
COMPASS Pathways

Recruiting

A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

Major Depressive Disorder

United States
Bioxytran Inc.

Not yet recruiting

To Evaluate the Safety, Efficacy,and Pharmacokinetics of Orally Administered Prolectin-M

COVID-19 | SARS CoV 2 Infection
Intra-Cellular Therapies, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ITI 333 in Healthy Volunteers

Healthy Volunteers

United States
Peking University

Not yet recruiting

Phase Ib Clinical Study on the Safety, the Tolerability, the Pharmacokinetics and the Efficacy of ScTIL Injection (Gene Modified Tumor Infiltrating Lymphocytes) Alone and in Combination With B Lymphocyte Adjuvant in the Treatment of Digestive System Malignant Solid Tumors

Digestive System Malignant Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Bioequivalence Study of INS062 and Pharmacokinetics and Pharmacokinetics Study of Single Injection of HR20014 in Healthy Subjects

Diabetes

China
Astellas Pharma Global Development, Inc.

Recruiting

A Study of ASP1002 in Adults for Treatment of Solid Tumors

Advanced Solid Tumors

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Escalating Doses of SIM0348 as a Single Agent in Advanced Solid Tumors

Advanced Solid Tumors
Dongyang Liu

Recruiting

Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects

Health, Subjective | Nonvalvular Atrial Fibrillation

China
Merck Sharp & Dohme LLC

Recruiting

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart Failure | Left Ventricular Systolic Dysfunction

Korea, Republic of, United States, France, Finland, Portugal, Sweden, Denmark, Spain, Turkey, Hungary, Netherlands, Ireland, Malaysia, Colombia, Germany, Singapore, Thailand, Italy, New Zealand, Belgium, Brazil, Canada, United Kingdom, South Africa
Arcturus Therapeutics, Inc.
Novotech CRO

Recruiting

Safety, Tolerability, and Pharmacokinetics of ARCT-032 in Healthy Adult Subjects and Adults With Cystic Fibrosis.

Cystic Fibrosis

New Zealand
Onconic Therapeutics Inc.

Not yet recruiting

Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy Volunteers

Healthy

Korea, Republic of
L & L biopharma Co., Ltd., Shanghai China

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors（MEETCD8-001） (MEETCD8-001)

Solid Tumor

China
Addpharma Inc.

Recruiting

A Study to Assess the Safety and Pharmacokinetics of AD-104-A

Hyperlipidemias

Korea, Republic of
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal

Recruiting

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II (APPEASEDII)

Diabetes Mellitus, Type 2 | Type 2 Diabetes | Platelet Aggregation | Aspirin | Platelet Aggregation Inhibitors

Canada
Keymed Biosciences Co.Ltd

Recruiting

Study to Evaluate Pharmacokinetics, Safety and Efficacy of CM310

Healthy

China
Haukeland University Hospital

Recruiting

NAD-brain: a Pharmacokinetic Study of NAD Replenishment Therapy (NAD-brain)

Healthy

Norway
Incyte Corporation

Recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis

Kidney Diseases | Renal Insufficiency

United States, Germany
Shanghai Yinnuo Pharmaceutical Technology Co.,...
Huashan Hospital

Not yet recruiting

Drug Drug Interaction (DDI) Between Supaglutide and Digoxin or Metformin

Healthy Volunteers
Zhongnan Hospital

Not yet recruiting

Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma

MGMT-Unmethylated Glioblastoma
Assistance Publique - Hôpitaux de Paris

Recruiting

Oral Glibenclamide in Preterm Infants With Hyperglycaemia (GALOP) (GALOP)

Preterm | Transient; Hypoglycemia, Neonatal | Glibenclamide Adverse Reaction

France
University of Mississippi Medical Center
Eli Lilly and Company

Recruiting

Empagliflozin in ESKD - A Feasibility Study

Heart Failure | Kidney Failure, Chronic

United States
University Health Network, Toronto
The Physicians' Services Incorporated Foundation

Not yet recruiting

Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane Oxygenation (Vol-ECMO)

Respiratory Failure
University of Liverpool
Infectious Diseases Institute, Makerere University College of Health Sciences and other collaborators

Recruiting

Pharmacokinetics of Antimalarials in Breastfeeding Ugandan Mother-infant Pairs (MILK Malaria)

Malaria,Falciparum

Uganda
ViiV Healthcare
Janssen Research & Development, LLC

Recruiting

Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics

HIV Infections

United States
argenx

Recruiting

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Healthy Volunteers

Netherlands
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Population Pharmacokinetics/Pharmacodynamics of Carbapenems in Febrile Neutropenia Patients

Febrile Neutropenia | Pharmacokinetics | Pharmacodynamic | Carbapenems

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