Search clinical trials for: Programmed Death Receptor

Total 20161 results

Genentech, Inc.

Completed

A Study of Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [FIR]

Non-Small Cell Lung Cancer

United States, France, United Kingdom, Belgium, Netherlands
Genentech, Inc.

Completed

A Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PDL1] Antibody) to Evaluate Safety, Tolerability and Pharmacokinetics in Participants With Locally Advanced or Metastatic Solid Tumors

Hematologic Malignancies | Tumors

Spain, France, United States, United Kingdom
Cancer Institute and Hospital, Chinese Academy...

Unknown

GR1405 Injection in Patients With Advanced Solid Tumor or Lymphoma

Lymphoma | Tumor, Solid

China
City of Hope Medical Center
Addario Lung Cancer Medical Institute

Withdrawn

ALCMI-005: Pembrolizumab and Epacadostat in Treating Patients With Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Carcinoma

United States
Vanderbilt University Medical Center
University of California, San Francisco; California Transplant Donor Network

Completed

The Effect of Nebulized Albuterol on Donor Oxygenation

Brain Death | Pulmonary Edema | Organ Donor

United States
Icahn School of Medicine at Mount Sinai

Completed

Aspirin Resistance and Percutaneous Coronary Intervention (PCI) (RESIST)

Stable Angina

United States
National Institute of Diabetes and Digestive and...
Office of Dietary Supplements (ODS)

Completed

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT) (FAVORIT)

Cardiovascular Disease | Death | Chronic Kidney Disease

United States, Canada, Brazil
St. Renatus, LLC
Rho, Inc.; Triligent International

Completed

Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Pediatric Patients

Anesthesia

United States
James Ahlgren

Withdrawn

Monoclonal Antibody Therapy and Colony- Stimulating Factor in Treating Patients With Metastatic Colorectal Cancer

Colorectal Cancer

United States
MedImmune LLC

Terminated

A Phase 1b/2 Safety and Tolerability Study of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies (MEDI6469)

Advanced Solid Tumors | Aggressive B-cell Lymphomas

United States
David Haines, MD
Medtronic BRC

Terminated

Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial (Shock n Block)

Ventricular Fibrillation | Tachycardia, Ventricular | Cardiac Arrest | Sudden Cardiac Death

United States
Ain Shams University

Unknown

Aspirin Versus Clopidogrel Effect on Uterine Blood Flow in Women With Unexplained Recurrent Miscarriages

Recurrent Pregnancy Loss

Egypt
Ottawa Heart Institute Research Corporation

Completed

A Study of Caffeine on Cardiac Arrhythmias (CACOA-HEART)

Atrial Fibrillation | Supraventricular Tachycardia (SVT)

Canada
National Taiwan University Hospital

Completed

Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease

Mycobacterium Avium

Taiwan
Institut de Cancérologie de Lorraine

Completed

Prognostic Impact of Programmed Death Ligand-1 Expression in Advanced Endometrial Cancer

Endometrial Cancer
Assistance Publique - Hôpitaux de Paris

Unknown

Definition of an Immune Signature Predictive of Anti-PD1 (Programmed Death-1) Antibody in the Treatment of Advanced Melanoma (PREDIMEL)

Malignant Melanoma
Novartis Pharmaceuticals

Terminated

This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure (PARADIGM-HF)

Heart Failure With Reduced Ejection Fraction

China, Germany, United States, Colombia, Korea, Republic of, Romania, South Africa, Canada, Belgium, Estonia, Hungary, Italy, Russian Federation, Taiwan, Turkey, United Kingdom, Spain, France, Netherlands, Hong Kong, Bulgaria, Israel and more
AstraZeneca

Completed

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin (PEGASUS)

Myocardial Infarction | Stroke | Atherothrombosis | Cardiovascular Death

Sweden, United States, Australia, Brazil, Bulgaria, Czech Republic, France, Italy, Korea, Republic of, Peru, Poland, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Philippines, China, Hungary, Romania, U... and more
Second Military Medical University

Unknown

Immunotherapy Using Pluripotent Killer-Programmed Cell Death 1 (PIK-PD-1) Cells for the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
University Medical Center Goettingen
KU Leuven; UMC Utrecht; University of Athens

Completed

An Arrhythmia Risk Stratification and Genetic Trial (EUTrigTreat)

Arrhythmia | Calcium Metabolism Disorders | Sudden Cardiac Death | Cardiomyopathies, Primary

Belgium, Germany, Greece, Netherlands
Amgen

Completed

Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma

Sarcoma | Soft Tissue Sarcoma | Locally Advanced or Metastatic, Unresectable Soft Tissue Sarcoma
Chonnam National University Hospital

Unknown

Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome (BEAUTY-II)

Myocardial Infarction | Hemorrhage | Cerebrovascular Accident | Cardiac Death

Korea, Republic of
Bristol-Myers Squibb

Completed

Safety Study of IL-21/Anti-PD-1 Combination in the Treatment of Solid Tumors

Neoplasms by Site

United States
CERESPIR

Completed

Safety, Pharmacokinetics and Pharmacodynamics Study of Treatment With CHF 5074 in Healthy Young Male Subjects (CT01)

Alzheimer's Disease

United States
Merck KGaA, Darmstadt, Germany
Merck N.V.-S.A., Belgium

Terminated

An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen

Multifollicular Stimulation

Belgium
Chiesi Farmaceutici S.p.A.

Completed

Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Open Label Extension (CT04 OLEP)

Alzheimer's Disease

United States, Italy
University of California, San Francisco

Completed

Concomitant Administration of FSH With HCG Improves Oocyte Maturation and Quality Double -Blinded Randomized Trial

Infertility

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of LCL161 in Patients With Solid Tumors

Advanced Solid Tumors

United States
Meir Medical Center

Unknown

Induction of Labor in Oligohydramnios

Cervical Ripening

Israel
Bristol-Myers Squibb

Withdrawn

Safety Study of Anti-Programmed Death-Ligand 1 in Hematologic Malignancy

Multiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin's Lymphoma | Chronic Myelogenous Leukemia
Hallym University Medical Center

Unknown

Valsartan Efficacy on Modest Blood Pressure Reduction in Acute Ischemic Stroke (VENTURE)

Acute Ischemic Stroke

Korea, Republic of
Daiichi Sankyo, Inc.

Completed

Study of CS-1008 in Patients With Advanced Solid Malignancies and Lymphomas (Without Leukemic Component)

Lymphoma | Malignancies

United States
European Institute of Oncology

Recruiting

Characterization of Biophysical and Mechanical Parameters on Skin of Breast Cancer Patients

Breast Cancer | Estrogen Receptor Positive Tumor

Italy
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of HRS5580 in Prevention of Postoperative Nausea and Vomiting of Adults

Preventing of Postoperative Nausea and Vomiting in Adults

China
Atif Shafqat

Recruiting

Opioid-based Versus Opioid-free Anaesthesia for Laparoscopic Cholecystectomy

Laparoscopic Cholecystectomy | Surgical Procedure, Unspecified

Pakistan
Assaf-Harofeh Medical Center

Recruiting

Comparison of the Effect of K Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Induced Following Treatment With Remifentanil

Cholecystectomy

Israel
Vejle Hospital
University of Aarhus; University of Southern Denmark; Region of Southern Denmark and other collaborators

Not yet recruiting

Reducing Breathlessness With Dronabinol in COPD Patients (BONG)

Cannabis | COPD | Breathlessness
Xuanwu Hospital, Beijing

Recruiting

China Healthy Aging Cohort Study (China-Ageing)

Death | Dementia | Disability | Age Problem

China
University of Pittsburgh
Fogarty International Center of the National Institute of Health; K S Hegde...

Not yet recruiting

Prucalopride for Cognitive Functioning in Schizophrenia

Schizophrenia

India
AstraZeneca
Fortrea

Not yet recruiting

Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma. (ARRIVAL)

Severe Asthma
Antonios Likourezos

Not yet recruiting

A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache

Migraine

United States
Santa Chiara Hospital

Recruiting

Evaluation of Clinical Outcomes of Chemotherapy or Androgen-receptor Targeting Agent (Alone or Combined) or Radiotherapy on Primary Tumor in Addition to Androgen Deprivation Therapy in HOrmone-Sensitive Metastatic Prostate Cancer Patients (ECHOS)

Prostate Cancer | Metastatic Tumor | Hormone Sensitive Prostate Cancer

Italy
University of Chicago

Not yet recruiting

Effects of Drugs on Stress Memories (ETS)

Stress | THC

United States
AstraZeneca

Not yet recruiting

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma (BAIYUN)

Asthma

China
Shanghai Changzheng Hospital
The First Affiliated Hospital of Nanchang University; Shanghai Zhongshan Hospital and other collaborators

Not yet recruiting

The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis

Hypertension, Portal
Fudan University

Not yet recruiting

Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancer

Advanced Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer

China
Poznan University of Medical Sciences

Not yet recruiting

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Knee Osteoarthritis | Knee Arthritis | Knee Pain Chronic | Knee Disease

Poland
Peking University First Hospital
Peking University International Hospital; Tianjin Medical University General...

Not yet recruiting

Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

Delirium | Dexmedetomidine | Aged | Intensive Care Units | Esketamine | Ventilators, Mechanical

China
University of California, Davis
Knownwell

Recruiting

CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

Obesity

United States
United States Army Research Institute of Environmental...

Not yet recruiting

The Effects of Semaglutide on Body Composition and Performance in Military Personnel

Obesity

Search clinical trials for: Programmed Death Receptor

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