Search clinical trials for: Very Severe Aplastic Anemia

Total 13935 results

City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Flu Vaccine in Preventing Influenza Infection in Healthy Volunteers and in Patients Who Have Undergone Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants (EPO)

Anemia, Neonatal | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure (Preemie iNO)

Pneumonia | Sepsis | Hypertension, Pulmonary | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn | Respiratory Distress Syndrome (RDS)

United States
Novartis Pharmaceuticals

Completed

Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias

Myelodysplastic Syndromes | Fanconi Syndrome | Anemia, Aplastic | Beta-thalassemia | Anemia, Diamond-Blackfan

United States
Jason Robert Gotlib
Celgene Corporation

Terminated

Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia

Leukemia | Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML)

United States
Neena Kapoor, M.D.

Withdrawn

Unrelated HSCT in Patients With Fanconi Anemia

Fanconi Anemia

United States
Shengyun Lin

Completed

Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia (MCSAA)

Aplastic Anemia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gene Therapy for the Treatment of Fanconi's Anemia Type C

Pancytopenia | Fanconi's Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Neuropsychological Effects of Immunosuppressive Treatment in Subjects With Aplastic Anemia

Aplastic Anemia

United States
Prolong Pharmaceuticals

Completed

A Phase 1 Safety Study of SANGUINATE™ In Patients With Acute Severe Anemia.

Acute Anemia

United States
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); Children's Hospital Medical...

Completed

Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia

Fanconi Anemia

United States
Tufts Medical Center

Terminated

A Phase II Study of Umbilical Cord Blood Transplantation

Lymphoma | Leukemia | Multiple Myeloma | Aplastic Anemia

United States
Postgraduate Institute of Medical Education and...

Terminated

Trial of an Alternate Mode of Providing Artificial Breaths to Children With Very Severe Pneumonia (APRiCE)

Acute Respiratory Distress Syndrome (ARDS)

India
M.D. Anderson Cancer Center

Terminated

Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL)

Leukemia

United States
Pearl Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PT001, PT003, and PT005 Following Chronic Dosing (7 Days) in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Australia, United States, New Zealand
Pearl Therapeutics, Inc.

Completed

24-hour Lung Function in Subjects With Moderate to Very Severe COPD After Treatment With PT003, Open-Label Spiriva® Respimat® as an Active Control, and Placebo

COPD
Vanderbilt University
National Cancer Institute (NCI)

Completed

Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms | Methemoglobinemia

United States
Hebei Medical University

Unknown

Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Aplastic Anemia

Aplastic Anemia

China
Beth Israel Deaconess Medical Center
Amgen

Completed

Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders (MINI HEME)

AML | MDS | CLL | ALL | CML Chronic Phase, Accelerated Phase, or Blast Crisis | RELAPSED NON-HODGKIN'S OR HODGKIN'S LYMPHOMA | APLASTIC ANEMIA | MULTIPLE MYELOMA | MYELOPROLIFERATIVE DISORDER (P Vera, CMML, ET)
Pearl Therapeutics, Inc.

Completed

Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD); (PINNACLE 1)

Chronic Obstructive Pulmonary Disease

United States, Australia, New Zealand
Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Pearl Therapeutics, Inc.

Completed

Extension Study to Evaluate the Safety and Efficacy of PT003, PT001, and PT005 in Subjects With Moderate to Very Severe COPD, With Spiriva® Handihaler® (PINNACLE 3)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Australia, New Zealand
Children's Hospital Los Angeles
Lucile Packard Children's Hospital

Terminated

Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells

Metabolic Diseases | Stem Cell Transplantation | Chronic Granulomatous Disease | Bone Marrow Transplantation | Thalassemia | Wiskott-Aldrich Syndrome | Genetic Diseases | Peripheral Blood Stem Cell Transplantation | Pediatrics | Diamond-Blackfan Anemia | Allogeneic Transplantation | Combined Immune Deficiency | X-linked Lymphoproliferative Disease
Novartis

Completed

Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload

Myelodysplastic Syndromes | Hemoglobinopathies | Diamond-Blackfan Anemia | Transfusional Iron Overload | Other Inherited or Acquired Anaemia | MPD Syndrome | Other Rare Anaemias

Australia
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Fanconi Anemia | Adult Acute... and other conditions

United States
Fundacion Infant

Completed

Role of Human Milk Bank in the Protection of Severe Respiratory Disease in Very Low Birth Weight Premature Infants

Respiratory Infections

Argentina
Singapore General Hospital
Shanghai Yueyang Integrated Medicine Hospital; Singapore Bao Zhong Tang TCM...

Completed

Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders

Myelodysplastic Syndrome (MDS) | Myelofibrosis (MF) | Thalassemia Intermedia | Aplastic Anaemia (AA)

Singapore
University Hospital, Grenoble

Terminated

Telaprevir Exposure and Severe Anemia in HCV Infected Patients Treated by Tri-therapy (Ribatela)

C Hepatitis, Tri Therapy

France
London School of Hygiene and Tropical Medicine
Department of State for Health and Social Welfare, The Gambia

Completed

Prevention of Severe Anaemia in Gambian Children

Anemia

Gambia
Pearl Therapeutics, Inc.

Completed

Glycopyrronium and Formoterol Fumarate (GFF) Metered Dose Inhaler (MDI) Dose Indicator Study in Adults With Moderate to Very Severe COPD

COPD

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donor

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia | Aplastic Anemia | Hodgkin's Disease | Biphenotypic Leukemia | Plasma Cell Neoplasms

United States
AbbVie
Boehringer Ingelheim

Completed

Single Rising Dose Study of BI 655066 in Patients With Moderate and Severe Psoriasis

Psoriasis

United States, Germany, United Kingdom
Columbia University

Completed

High-Tc Susceptometer to Monitor Transfusional Iron Overload

Myelodysplastic Syndromes | Sickle Cell Disease | Aplastic Anemia | Transfusional Iron Overload | Thalassemia Major

United States
Mallinckrodt

Terminated

Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide

Sickle Cell Disease | Pulmonary Hypertension | Lung Disease | Lung Transplant | Cardiac Transplant

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Miltenyi Biotec, Inc.

Completed

Hematopoietic Stem Cell Transplantation for Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using Total Body Irradiation, Cyclophosphamide and Fludarabine

Fanconi Anemia

United States
AstraZeneca

Completed

Epanova® for Lowering Very High Triglycerides (EVOLVE)

Severe Hypertriglyceridemia

United States, Hungary, India, Russian Federation, Denmark, Ukraine, Netherlands
Beth Israel Deaconess Medical Center
Bayer

Completed

Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | AML | Myelodysplastic Syndrome | Aplastic Anemia | Myeloproliferative Disorder | CLL | ALL

United States
Peking Union Medical College Hospital
Novartis

Unknown

Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload

Iron Overload | Aplastic Anemia | Dysmyelopoietic Syndromes
National Heart, Lung, and Blood Institute (NHLBI)
Children's Hospital Medical Center, Cincinnati

Completed

Blood Cell Collection for Future Use in Individuals With Fanconi Anemia

Fanconi Anemia

United States
National Guard Health Affairs

Unknown

HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen

Sickle Cell Disease

Saudi Arabia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia

Chronic Myelomonocytic Leukemia | Fanconi Anemia | Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute... and other conditions

United States
Beth Israel Medical Center

Completed

Extended Platelet Parameters as a Means to Differentiate Immune Thrombocytopenia From Hypo-proliferative Thrombocytopenias.

Immune Thrombocytopenia | Myelodysplasia | Chemotherapy Induced Thrombocytopenia | Aplastic Anaemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Drug Etiology of Aplastic Anemia and Related Dyscrasias

Purpura, Thrombocytopenic | Agranulocytosis | Anemia, Aplastic | Blood Disease
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Etiology of Blood Dyscrasias: Analysis of the International Agranulocytosis and Aplastic Anemia Study Data

Agranulocytosis | Anemia, Aplastic | Blood Disease
University Hospital, Tours

Completed

Evaluation of Benefit of Nebulized Bronchodilators at Home in Severe Chronic Obstructive Pulmonary Disease and Very Severe Steady State (Nebuadom)

Severe Chronic Obstructive Pulmonary Disease

France
Shandong University

Withdrawn

Collection of Blood and Bone Marrow From Patients With Aplastic Anemia for Analysis of Adhesion Molecules, Chemokines and Their Receptors

Healthy | Aplastic Anemia

China
Massachusetts General Hospital

Completed

RBC Transfusion in Severe Anemia With Lactic Acidosis (TOTAL)

Anemia

Uganda
National Institute of Blood Disease Center, Pakistan

Unknown

Comparison of Two Different Doses of Rabbit ATG-Fresenius With Cyclosporin in the Treatment of Acquired Aplastic Anaemia (ATG)

Aplastic Anemia

Pakistan
Nagoya University

Unknown

Randomised Study Comparing Different Dosages of Rabbit ATG in Patients With SAA

Acquired Aplastic Anemia.

Japan
Hospital Clinic of Barcelona

Completed

Intravenous Iron Versus Oral Iron for Severe Postpartum Anemia

Anemia | Puerperal Disorders

Spain

Search clinical trials for: Very Severe Aplastic Anemia

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