Search clinical trials for: dose reduction

Total 25105 results

KARANAHAN

Recruiting

Clinical Study of Personalized Chemotherapy for Breast Cancer With Low Doses of Cyclophosphamide

Stage IV Breast Cancer

Russian Federation
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance in Age

Aging

France
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Boston Children's Hospital

Not yet recruiting

GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health) (GF-NOURISH)

Celiac Disease in Children | Nutrition Disorder, Child

United States
AstraZeneca

Recruiting

A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants

Healthy Participants

United States
Nova Scotia Health Authority

Not yet recruiting

Evaluation of an Anxiety Reduction Tool During Thyroid and Prostate Biopsy Procedures

Anxiety State
Hospital for Special Surgery, New York

Not yet recruiting

Opioid Dispenser for Microdiscectomy/Laminectomy

Pain, Postoperative | Opioid Use | Medical Device | Laminectomy | Diskectomy

United States
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
GlaxoSmithKline

Recruiting

A Study to Investigate the Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With GSK3036656 in Female Participants of Non-childbearing Potential Aged 18 to 65 Years of Age

Tuberculosis

Spain
Jasper Therapeutics, Inc.

Recruiting

A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines (SPOTLIGHT)

Chronic Inducible Urticaria

Germany
University Hospital, Limoges

Not yet recruiting

Evaluation of the Benefits of Administering Immunosuppressive Drugs as Single Daily Doses Over the First Year After Liver Transplantation (EASY) (EASY)

Liver Transplantation | Immunosuppression

France
Rigshospitalet, Denmark
The Novo Nordic Foundation

Not yet recruiting

Preventive Interventions for Chronic Pain Worsening

Chronic Non-Cancer Pain
The George Institute
University of Calgary; Berry Consultants

Not yet recruiting

ACT-GLOBAL Adaptive Platform Trial for Stroke (ACT-GLOBAL)

Stroke
Hong Kong Metropolitan University

Not yet recruiting

The Effectiveness of MIND Diet and Forest Bathing on Stress Reduction

Depression | Stress | Anxiety | Psychological Stress

Hong Kong
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

Cognitive Impairment | Cannabis Use | Impaired Driving

United States
Boehringer Ingelheim

Recruiting

A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Healthy Men and People With Overweight or Obesity

Healthy

Germany
Sichuan University

Not yet recruiting

Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors

Solid Tumor
Angiowave Imaging

Not yet recruiting

Clinical Evaluation of Radiation Reduction for Optimized Safety (CERROS)

Myocardial Infarction | Coronary Artery Disease | Coronary Disease | Chest Pain | Angina Pectoris | Coronary Stenosis

United States
China-Japan Friendship Hospital

Not yet recruiting

Safety and Efficacy of Endobronchial Valve for Bronchoscopic Lung Volume Reduction Surgery: A Prospective Pilot Study

Chronic Obstructive Pulmonary Disease | Emphysema

China
Cosima Locher
Brown University; University of Basel

Not yet recruiting

Conditioned Open-label Placebos to Facilitate Opioid Reduction in Patients With Chronic Non-cancer Pain (ROM)

Chronic Non-cancer Pain
Equilibra Bioscience LLC

Recruiting

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B)

Hemophilia A | Hemophilia B | Healthy Participants

United States
Aya Ayman Ahmed

Not yet recruiting

Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study

Mandibular Fractures
Istanbul Nisantasi University

Recruiting

The Effect of Mindfulness-Based Stress Reduction Training Before Mastectomy on Postoperative Pain in Early Period

Pain Management

Turkey
Peking University Third Hospital

Not yet recruiting

A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+)

Respiratory Distress Syndrome of Newborn
7 Generation Games

Not yet recruiting

Efficacy of Digital Problem Solving Application in Reduction of Anxiety, Depression and Substance Use Disorder Symptoms (Efficacy)

Anxiety | Depressive Symptoms | Substance Use Disorders
Martha Sajatovic

Recruiting

Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care

Epilepsy

United States
Portal Therapeutics, Inc.

Not yet recruiting

Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of PORT-77 Administered to Healthy Adult Participants

Healthy Adult Participants

United States
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

A Study to Learn How Various Tablets of the Study Medicine Vepdegestrant Are Taken up Into the Blood of Healthy Adults

Healthy

United States
University of Bath
National Institute for Health Research, United Kingdom; Oxford Health NHS Foundation... and other collaborators

Not yet recruiting

Compassion Project: Developing an Empathy-Based Stress Intervention

Reduction of Empathy-Based Stress in Healthcare Staff
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial)

Acute Kidney Injury Post Liver Transplantation

France
Dosentrx Ltd.

Not yet recruiting

Open Label, Controlled, Post Marketing, Registry Study of Ribociclib (Ribo) Treatment Adherence and Patient Reported Outcomes in Participants Using ReX Technology Platform

Any Solid Oral Medication

United States
M.D. Anderson Cancer Center
Incyte Corporation

Not yet recruiting

High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

Myelofibrosis | Splenomegaly

United States
Zhongnan Hospital
Shanxi Province Cancer Hospital; Ruijin Hospital; The First Affiliated Hospital... and other collaborators

Recruiting

MA+AZA Regimen for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukaemia

China
VIST - Faculty of Applied Sciences

Recruiting

The Effect of 8-week Dietary Intake of Novel Food Supplement on Minimal Erythema Dose (VIST-TO-UV)

Minimal Erythema Dose

Slovenia
University Health Network, Toronto
Centre for Addiction and Mental Health

Recruiting

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin (PSI-1V2)

Depression | Mood Disorders | Major Depressive Disorder | Treatment-Resistant Depression

Canada
Encora, Inc.

Recruiting

Upper Limb Tremor Reduction in Essential Tremor Patients (ULTRE)

Essential Tremor

United States
University Hospital, Basel, Switzerland

Not yet recruiting

Targeted Radionuclide Therapy in Metastatic Prostate Cancer Using a New PSMA Ligand Radiolabelled With Terbium-161 (161Tb-SibuDAB) - Dose Identification/Escalation Phase Ia/b Study (PROGNOSTICS)

Castration-resistant Prostate Cancer

Switzerland
Benjamin Galipeau
Fonds de recherche du Québec - Société et culture; Fonds pour la prévention...

Recruiting

Prevention Messages for EGMs: Effects on Behaviours and Cognitions

Gambling

Canada
BeiGene

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035

Autoimmune Diseases | Healthy Volunteers | Healthy Subjects | Healthy Participants | Healthy Adult Participants

Australia
Thammasat University Hospital

Recruiting

Comparing Single Dose and Multiple Dose of Dexamethasone Post TKA

Pain, Postoperative | Osteo Arthritis Knee

Thailand
Samsung Medical Center

Recruiting

Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI (Lipid-PCI)

Coronary Artery Disease | Hyperlipidemias

Korea, Republic of
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Healthy

Germany
University of California, Riverside

Not yet recruiting

Preventing Alcohol Use Disorders and Alcohol-Related Harms in Pacific Islander Young Adults

Alcohol; Harmful Use | Alcohol Use Disorder

United States
Gilead Sciences

Not yet recruiting

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Temple University
National Institute on Disability, Independent Living, and Rehabilitation...

Recruiting

Creating Welcoming Faith Communities for People With Serious Mental Illnesses

Other

United States
Population Health Research Institute

Not yet recruiting

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial (BRACKETS)

Chronic Kidney Diseases | Bleeding | Surgery | Acute Kidney Injury
Wang Xin

Not yet recruiting

Prophylaxis of Graft-versus-host Disease With Anti-CD25 Antibody in Patients Underwent HSCT

GVHD

China
Jean Marino

Not yet recruiting

Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Reduction During Intrauterine Device (IUD) Insertion in Outpatient Gynecology

IUD Insertion Pain

United States
Dosentrx Ltd.
US Oncology Research

Recruiting

Non-randomized Observational Study to Evaluate ReX® in the Management of Solid Oral Medication. (RegStud)

Any Solid Oral Medication

United States
Swansea University

Recruiting

Isometric Handgrip Training Frequency and Blood Pressure in People With Hypertension

Hypertension

United Kingdom

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