Search clinical trials for: dose-finding study

Total 119067 results

Cambridge University Hospitals NHS Foundation Trust

Recruiting

Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study (IVORY-FINALE)

Acute Coronary Syndromes

United Kingdom
Tongji Hospital

Not yet recruiting

A Study of Cadonilimab（AK104）Combined With Standard Treatment for Function Preservation in Urinary System Tumors

Urinary System Tumor
Dr R Viswa Chandra

Recruiting

Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph Study

Intrabony Periodontal Defect

India
Janssen Research & Development, LLC

Not yet recruiting

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (MajesTEC-10)

Relapsed or Refractory Multiple Myeloma
Lu Hua

Not yet recruiting

Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study

Breast Cancer Patients With Chronic Pain After Surgery

China
Chinese University of Hong Kong

Not yet recruiting

Smartwatch Paroxysmal Arrhythmia Detection Compared With Holter

Arrythmia
The Affiliated Hospital Of Guizhou Medical University
Affiliated Hospital of Guizhou Medical University; Chinese nursing association

Recruiting

Machine Learning-based Longitudinal Study of Post-ICU Syndrome Development Trajectory in Critically Ill Patients and Construction of Clinical Early Warning Models: a Research Protocol for Longitudinal Study

Developmental Trajectory of Patients With Post-ICU Syndrome | Development and Application of Post-ICU Syndrome Prediction Model

China
University of Copenhagen
Rigshospitalet, Denmark

Recruiting

The Role of GIP in Postprandial Splanchnic Blood Flow Distribution and Metabolism in Patients With Type 2 Diabetes (GA-17b)

Blood Flow

Denmark
Fudan University

Recruiting

Clinical Study of T3011 Intravesical Instillation for Treatment of NMIBC Patients

Bladder Cancer

China
Amy Wagner
The Beckwith Institute

Not yet recruiting

mindBEAGLE: Unlocking Functional Communication for Patients With Disorders of Consciousness

Disorders of Consciousness

United States
Ping An

Not yet recruiting

A Multimodal Wearable Device-based Study to Evaluate the Efficacy of an Exercise Prescription Intervention in IBD

Inflammatory Bowel Diseases
Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

Registry Study to Determine the Effectiveness and Safety of Weight Loss With Enavogliflozin in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Georgiamune Inc

Recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

Solid Tumor | Melanoma Stage IV

United States
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia

Acute Lymphoid Leukemia

China
Henan Cancer Hospital

Not yet recruiting

This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma

Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell
Peking Union Medical College Hospital

Not yet recruiting

A Prospective Study on the Treatment of Recurrent/Refractory/Intolerable NSAA With Lusutrombopag

Aplastic Anemia

China
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Longitudinal Study of Gene Expression in the Human Placenta During First-trimester and Full-term Pregnancy at the Single Cell Level (VilliRNAseq)

Pregnancy Related

France
Sun Pharmaceutical Industries Limited

Not yet recruiting

A Study to Assess Sebaceous Gland Changes and Constituents of Sebum (Skin Oil) Induced by Clascoterone 1% Cream in Acne Patients

Acne Vulgaris

United States
Innolake Biopharm

Not yet recruiting

A Study of the ILB-3101 in Patients With Advanced Solid Tumors

Advanced Solid Tumor
Fudan University
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Exploratory Clinical Study of HRS-4642 Combined With Adebelimab in the Treatment of Advanced Pancreatic Cancer

Pancreatic Cancer

China
Zydus Therapeutics Inc.

Not yet recruiting

Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Turkey, Argentina
Heinrich-Heine University, Duesseldorf

Not yet recruiting

Work Package 3 Education for ICU Clinicians in Basic Palliative Care

ICU | Learning | Staff Attitude | Palliative Care, Patient Care
European Association of Urology Research Foundation
National Cancer Institute (NCI); UMC Utrecht; Erasmus Medical Center; University... and other collaborators

Not yet recruiting

Prostate Cancer Awareness and Initiative for Screening in the European Union (PRAISE-U)

Prostate Cancer
University of Roma La Sapienza

Recruiting

Use of 'Mechanical Power' as a Predictor of Increased Serum and Pulmonary Proinflammatory Cytokine Concentrations in Patients With Acute Hypoxemic Respiratory Failure: A Prospective Observational Study

Mechanical Power

Italy
The University of Texas Health Science Center,...

Recruiting

A Prospective Study on the Efficacy of the Karl Storz Curved Fetoscope (11508aak) and Its Straight Version (11506akk) for In-utero Surgery

In Utero Procedure Affecting Fetus or Newborn

United States
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

Chronic Hepatitis B

China
Celgene

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma (GOLSEEK-2)

Lymphoma, Follicular

United States, Australia, Brazil, Canada, Chile, France, Germany, Italy, Korea, Republic of, Poland, Spain, Taiwan, United Kingdom
Icahn School of Medicine at Mount Sinai

Not yet recruiting

Approach to Dance for Autism (ADAPT)

Autism Spectrum Disorder

United States
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis (BE TOGETHER)

Moderate to Severe Plaque Psoriasis

United States
Peking Union Medical College Hospital

Not yet recruiting

Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA

Aplastic Anemia

China
Hospices Civils de Lyon

Recruiting

Campylobacter Spp. Bone and Joint Infection: a Retrospective Cohort Study (Campylo-BJI)

Campylobacter Infections

France
Samsung Medical Center

Not yet recruiting

Pilot Study for the Validity of a Content-based Information Provision Tool Aimed at Improving the Hospitalization Experience of Liver Transplant Patients

Liver Transplantation | Inpatients
Keymed Biosciences Co.Ltd

Not yet recruiting

Study on the Treatment of Prurigo Nodularis With Stapokibart Injection

Prurigo Nodularis
Sociedad Española de Anestesiología, Reanimación...

Not yet recruiting

Study of Cardiorespiratory Arrests That Occurred in the Surgical Block and Adjacent Places

Cardiorespiratory Arrest
Boehringer Ingelheim

Not yet recruiting

A Study to Test Whether BI 690517 in Combination With Empagliflozin Helps People With Heart Failure

Heart Failure
Dartmouth-Hitchcock Medical Center
Dartmouth College; University of Massachusetts, Worcester

Not yet recruiting

Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application (SONATA)

Epilepsy | Refractory Epilepsy | Music

United States
Xie Kangjie

Recruiting

Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia

Pharmacokinetics | Hypoproteinemia | Ciprofol

China
Calico Life Sciences LLC
AbbVie

Recruiting

Study of [14C] ABBV-CLS-7262 in Healthy Male Volunteers Following Single Oral Dose Administration

Healthy Volunteer

United States
Biohaven Therapeutics Ltd.

Recruiting

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures (SHINE)

Generalized Epilepsy

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Not yet recruiting

Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior Anti-PD-(L)1 Therapy (JAVELIN DDRiver Bladder)

Urothelial Carcinoma

United States, Germany
Zeng Jian

Recruiting

A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC

Non Small Cell Lung Cancer

China
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Not yet recruiting

A Study of FZ-AD005 in Patients With Advanced Solid Tumors

Advanced Solid Tumor, SCLC(Small Cell Lung Cancer) or LCNEC (Large Cell Neuroendocrine Carcinoma)

China
University of Kansas Medical Center

Recruiting

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry (HF2 Registry)

Heart Failure

United States
University of Leicester

Recruiting

AFLETES-MRI: A Cardiac and Cerebral Magnetic Resonance Imaging Study in Athletes With Atrial Fibrillation (AFLETES-MRI)

Stroke | Atrial Fibrillation

United Kingdom
Bristol-Myers Squibb

Not yet recruiting

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Hepatic Impairment | Healthy Participants
University of Mons

Recruiting

Quantitative Assessment of Orofacial Muscle Function in FSHD

Facioscapulohumeral Muscular Dystrophy

Belgium
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients With CML (POLARIS-2)

Chronic Myeloid Leukemia | CML | CML, Chronic Phase

United States
Medical University of South Carolina

Not yet recruiting

Study of Fingolimod

Non Small Cell Lung Cancer | Small-cell Lung Cancer
Beijing Cancer Prevention & Treatment Society
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC (pre-FLAME)

Non Small Cell Lung Cancer

China
Alnylam Pharmaceuticals

Not yet recruiting

A Study to Evaluate Zilebesiran in Japanese Patients With Mild to Moderate Hypertension

Mild to Moderate Hypertension

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