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Search clinical trials for: genome-edited hematopoietic stem and progenitor cellular therapy
Total 474239 results
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedStage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Refractory Multiple MyelomaUnited States, Italy
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedPrimary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Paroxysmal Nocturnal Hemoglobinuria | de Novo Myelodysplastic Syndrome | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Refractory Anemia | Refractory Anemia With... and other conditionsUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedRefractory Hodgkin Lymphoma | Recurrent Adult Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | T-Cell Chronic Lymphocytic Leukemia | Recurrent Childhood Non-Hodgkin... and other conditionsUnited States, Germany
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedRecurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditionsUnited States, Italy
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Institut de Cancérologie de la LoireCentre Leon Berard; Hospices Civils de Lyon; Société BiophotonCompleted
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic... and other conditionsUnited States
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Universidade Federal do Rio de JaneiroMinistry of Health, Brazil; Rio de Janeiro State Research Supporting Foundation... and other collaboratorsCompletedChronic Kidney Diseases | Focal Segmental GlomerulosclerosisBrazil
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Johns Hopkins UniversityTerminatedUrinary Incontinence | Bladder ExstrophyUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.Completed
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedStage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditionsUnited States, Italy
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedStage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditionsUnited States, Germany, Italy
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Baylor College of MedicineThe Methodist Hospital Research Institute; Center for Cell and Gene Therapy...CompletedMultiple SclerosisUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedClear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent... and other conditionsUnited States, Germany, Italy
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Ronald LevyNational Institutes of Health (NIH)CompletedLymphoma, Mantle-CellUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedRecurrent Disease | Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Accelerated Phase of Disease | Chronic Phase of DiseaseUnited States, Germany, Italy
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedRecurrent Hodgkin Lymphoma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Mantle Cell Lymphoma | Waldenstrom Macroglobulinemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood... and other conditionsUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedStage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditionsUnited States, Germany, Italy
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedClear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Lymphoblastic Lymphoma | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute... and other conditionsUnited States, Germany, Italy
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National Institutes of Health Clinical Center (CC)CompletedDistress | Hematopoietic Stem Cell TransplantationUnited States
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KLE Society's Institute of Dental SciencesUnknown
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National Cancer Institute (NCI)CompletedGene TransferUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedChronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Anemia With Excess BlastsUnited States
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National Cancer Institute (NCI)Georgetown University; Hackensack Meridian HealthTerminatedMyeloma-Multiple | Myeloma, Plasma-Cell | MyelomatosisUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedPlasma Cell Myeloma | Refractory Plasma Cell MyelomaUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedHematopoietic and Lymphoid Cell Neoplasm | Recurrent Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Childhood Acute Lymphoblastic Leukemia | Plasma Cell Myeloma | Recurrent Diffuse Large B-Cell Lymphoma | Prolymphocytic Leukemia | Refractory Chronic... and other conditionsUnited States, Denmark
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Hongnan MoUnknownHematopoietic Stem Cell Transplantation | Thrombocytopoietin | Hematopoietic Stem Cell MobilizationChina
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M.D. Anderson Cancer CenterIntrexon CorporationTerminatedAcute Myeloid Leukemia | Hematopoietic/Lymphoid CancerUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedHematopoietic and Lymphoid Cell Neoplasm | Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditionsUnited States, Germany, Denmark
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University of ChicagoNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaboratorsCompletedKrabbe Disease | Mucopolysaccharidosis Type II (MPS II) | Mucopolysaccharidosis Type I (MPS I) | Mucopolysaccharidosis Type III (MPS III) | Mucopolysaccharidosis Type VI (MPS VI)United States
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OhioHealthCompletedKnee OsteoarthritisUnited States
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Roswell Park Cancer InstituteCompletedPrimary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditionsUnited States
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Kang Stem Biotech Co., Ltd.CompletedAtopic DermatitisKorea, Republic of
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Tower Outpatient Surgical CenterCompletedDiabetic Foot | Pressure Ulcer | Venous UlcerUnited States
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Centre Hospitalier National d'Ophtalmologie des...Etablissement Français du SangCompleted
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Masonic Cancer Center, University of MinnesotaTerminated
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TakedaCompletedAllogeneic Hematopoietic Stem Cell TransplantationUnited States
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Case Comprehensive Cancer CenterCompletedHematopoietic Stem Cell TransplantUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedStage IV Renal Cell Cancer | Recurrent Renal Cell CancerUnited States
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Abramson Cancer Center of the University of PennsylvaniaCompletedAcute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous LeukemiaUnited States
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Dana-Farber Cancer InstituteNational Cancer Institute (NCI); National Institute of Allergy and Infectious...CompletedMyelodysplastic Syndromes | LeukemiaUnited States
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Institute of Hematology & Blood Diseases HospitalUnknownMultiple Myeloma | Plasma Cell Leukemia | Extramedullary Plasmacytoma | Loss of Chromosome 17p | t(14;16) | t(4;14) | Complex Karyotype | T(14;20) | 1Q21 AmplificationChina
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City of Hope Medical CenterNational Cancer Institute (NCI)CompletedMultiple Myeloma and Plasma Cell NeoplasmUnited States
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IRCCS San RaffaeleOrchard Therapeutics; Fondazione TelethonUnknown
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Ankara UniversityUnknownPlacental Transfusion | Stem Cells
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedWaldenstrom Macroglobulinemia | Refractory Plasma Cell Myeloma | Recurrent Adult Hodgkin Lymphoma | Recurrent Adult Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Non-Hodgkin Lymphoma | Recurrent Plasma Cell Myeloma | Plasma Cell Leukemia and other conditionsUnited States
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The Republican Research and Practical Center for...The Republican Center for Research and Practice in Otolaryngology; Belarusian...CompletedMesenchymal Stem Cells | Tracheal Stenosis | Laryngeal StenosisBelarus
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AlloVirBaylor College of Medicine; The Methodist Hospital Research Institute; Center...Completed
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Millennium Pharmaceuticals, Inc.TerminatedAllogeneic Hematopoietic Stem Cell TransplantationUnited States, Belgium, Sweden, France, Norway
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National Heart, Lung, and Blood Institute (NHLBI)TerminatedGraft-Versus-Host DiseaseUnited States
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M.D. Anderson Cancer CenterProteonomix, Inc.CompletedBlood And Marrow TransplantationUnited States