Search clinical trials for: incretin effect

Total 149211 results

Albert Einstein College of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

New Onset Type 1 Diabetes: Role of Exenatide

Type 1 Diabetes

United States
Stefano Rizza

Completed

Quality of Life and Fixed-ratio Combination of Insulin Degludec and Liraglutide (iDegLira) (XETD2)

Type2 Diabetes

Italy
Theracos

Completed

Interaction of Bexagliflozin With Metformin, Glimepiride and Sitagliptin

Type2 Diabetes Mellitus

United States
Novo Nordisk A/S

Completed

A Research Study Looking at How Victoza® Works in People With Type 2 Diabetes in Iran, Followed in Local Clinical Routine (VIEW-Iran)

Diabetes Mellitus, Type 2

Iran, Islamic Republic of
Novo Nordisk A/S

Completed

A Regulatory Post-marketing Surveillance (rPMS) Study to Evaluate the Safety and Effectiveness of Saxenda®(Liraglutide 3.0 mg) in Obese Patients and Overweight Patients With Obesity-related Comorbidities in Routine Clinical Practice in Korea.

Obesity | Overweight

Korea, Republic of
Novo Nordisk A/S

Completed

Efficacy and Safety of Liraglutide in Combination With Metformin Compared to Metformin Alone, in Children and Adolescents With Type 2 Diabetes (Ellipse™)

Diabetes Mellitus, Type 2 | Diabetes

United States, Croatia, India, Russian Federation, Spain, United Kingdom, Austria, Belgium, Mexico, Sweden, Israel, Taiwan, Hungary, Malaysia, Serbia, Turkey, Denmark, Greece, Thailand, North Macedonia, Norway, Portugal, Germany, Romania and more
Jody Dushay
AstraZeneca

Completed

Weight Loss With Exenatide Treatment

Obesity

United States
Theracos

Completed

Safety and Efficacy of Bexagliflozin Compared to Sitagliptin as Add-on Therapy to Metformin in Type 2 Diabetes Subjects

Type 2 Diabetes Mellitus

United States, Japan, Czechia, Hungary, Poland, Spain
Radboud University Medical Center
Charite University, Berlin, Germany; University of Turku; University Medical... and other collaborators

Completed

68Ga-NODAGA-exendin-4 PET/CT for Diagnostic Imaging in AHH (GLP-1-AHH)

Insulinoma
Assistance Publique - Hôpitaux de Paris

Completed

Effect of GLP-1 on Angiogenesis (ANGIOSAFE 1)

Type 2 Diabetes

France
Amsterdam UMC, location VUmc
AstraZeneca

Completed

DECREASE: Dapagliflozin Plus Exenatide on Central REgulation of Appetite in diabeteS typE 2 (DECREASE)

Obesity | Type 2 Diabetes Mellitus

Netherlands
University of Miami

Withdrawn

Effects of DPP4 Inhibition on COVID-19

Coronavirus Infection | Type 2 Diabetes

United States
Beni-Suef University
Minia University

Completed

Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Egypt
Woman's
Novo Nordisk A/S

Completed

Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS (SAXAPCOS)

Polycystic Ovary Syndrome | Pre Diabetes | Obesity Android

United States
Anders Fink-Jensen, MD, DMSci
The Novavì outpatient clinics, Copenhagen; Neurobiology Research Unit, Rigshospitalet... and other collaborators

Completed

Does Treatment With GLP-1 Reduce Alcohol Intake in Patients With Alcohol Dependence? (EXALT)

Addiction, Alcohol | Alcohol Dependence, in Remission

Denmark
Rabin Medical Center

Terminated

Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients With Established COVID-19

Glucose Metabolism Disorders | Respiratory Tract Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | COVID 19 | Coronavirus | Metabolic Disease | Severe Acute Respiratory Syndrome Coronavirus 2 | Sars-CoV2 | Hormones | Hypoglycemic Agents | Incretins | Dipeptidyl-Peptidase IV Inhibitors and other conditions

Israel
Theracos

Completed

Bexagliflozin Drug/Drug Interaction Study With Exenatide Injection

Type2 Diabetes Mellitus

United States
OPKO Health, Inc.

Completed

A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Puerto Rico, Romania, Poland, Mexico, Greece
Heart Care Foundation
Fondazione dell'Associazione Medici Diabetologi

Completed

Effects of Linagliptin on Left Ventricular Myocardial DYsfunction in Patients With Type 2 DiAbetes Mellitus and Concentric Left Ventricular Geometry (DYDA2)

Diabetes Mellitus, Type 2 | Left Ventricular Systolic Dysfunction

Italy
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes

Type 2 Diabetes

United States
Imperial College London

Completed

Investigating Brown Adipose Tissue Activation in Humans

Metabolic Diseases

United Kingdom
Nick Giannoukakis, PhD
University of South Florida; AstraZeneca; University of Pittsburgh; National Institutes...

Completed

Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes

Type 2 Diabetes Mellitus | Insulin Resistance

United States
Steno Diabetes Center Copenhagen

Completed

Glucose-dependent Insulinotropic Polypeptide as a Safeguard Against Hypoglycemia in Patients With Type 1 Diabetes

Diabetes Mellitus, Type 1

Denmark
The Affiliated Hospital of Qingdao University

Completed

Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects

Healthy Subjects

China
University of Minnesota

Completed

Evaluating Exenatide for the Treatment of Postprandial Hyperinsulinemic Hypoglycemia

Hyperinsulinemic Hypoglycemia

United States
University of Copenhagen
Hvidovre University Hospital

Completed

Effect of Neprilysin on Glucagon-Like Peptide-1 in Patients With Type 2 Diabetes (NEPT2D)

Type2 Diabetes

Denmark
David D'Alessio, M.D.
Merck Sharp & Dohme LLC

Completed

DPP4 Inhibition & Beta Cell Function

Healthy

United States
University of Leicester
Novo Nordisk A/S

Active, not recruiting

Saxenda in Obesity Services (STRIVE Study) (STRIVE)

Obesity | Diabetes Mellitus | Weight Loss

Ireland, United Kingdom
Zoltan Pataky
University of Geneva, Switzerland

Completed

Reward Mechanisms in Obesity (LIRAOB)

Obesity

Switzerland
MedImmune LLC

Completed

A Study to Investigate the Effect of MEDI0382 on Hepatic Glycogen Metabolism in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.

Type 2 Diabetes Mellitus

Netherlands, Sweden
The University of Hong Kong

Completed

Metabolic Responses of Dapagliflozin vs Sitagliptin in T2DM Patients Inadequately Controlled With Insulin Therapy

Type 2 Diabetes | Ketonemia

Hong Kong
Zuyderland Medisch Centrum
Nederlandse Obesitas Kliniek

Withdrawn

Liraglutide for Low-responders After Bariatric Surgery (LIBAR)

Obesity | Obesity, Morbid
Second Xiangya Hospital of Central South University
The First Affiliated Hospital with Nanjing Medical University; Beijing Hospital and other collaborators

Completed

Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes

Diabetes Mellitus, Type 1

China
Novo Nordisk A/S

Completed

A Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function

Diabetes | Diabetes Mellitus, Type 1

United States, Israel, Italy, Poland, Russian Federation, United Kingdom, Canada, Denmark, Sweden, Austria, Belgium, Spain, Ireland, Norway, Serbia, Finland, Portugal, Ukraine
Novo Nordisk A/S

Completed

A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus. (DUAL™ I Japan)

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs (DUAL™ II Japan)

Diabetes Mellitus, Type 2 | Diabetes

Japan
Xiangya Hospital of Central South University

Withdrawn

The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients

Obesity

China
University of Illinois at Chicago

Completed

Islet Transplantation in Type 1 Diabetic Patients Using the Edmonton Protocol of Steroid Free Immunosuppression

Diabetes Mellitus, Type 1

United States
University of Colorado, Denver

Completed

Incretin Effect in People With Impaired Fasting Glucose (1651)

Obesity

United States
Royal Devon and Exeter NHS Foundation Trust
King's College London; Newcastle University; NHS Tayside; University of Dundee; University... and other collaborators

Completed

TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes. (TriMaster)

Type 2 Diabetes

United Kingdom
Hvidovre University Hospital
Odense University Hospital; Aarhus University Hospital; Bispebjerg Hospital; Hillerod... and other collaborators

Completed

Liraglutide in Newly Onset Type 1 Diabetes. (NewLira)

Diabetes Mellitus, Type 1

Denmark
Xiaojun Chen
Huashan Hospital

Withdrawn

Liraglutide Plus Megestrol Acetate in Endometrial Atypical Hyperplasia

Atypical Endometrial Hyperplasia | Fertility Issues | Obese
JW Pharmaceutical

Completed

MAGE of Anagliptin Compared With Sitagliptin With Type 2 Diabetes Mellitus (ACACIA)

Type 2 Diabetes

Korea, Republic of
Zealand Pharma
Massachusetts General Hospital; Beta Bionics, Inc.

Completed

Feasibility Trial Testing the Bionic Pancreas With ZP4207 (dasiglucagon)

Diabetes Mellitus, Type 1

United States
Hospital Regional de Alta Especialidad del Bajio

Completed

Dipeptidyl Peptidase-4 Inhibitor (DPP4i) for the Control of Hyperglycemia in Patients With COVID-19 (Covid19DPP4i)

Hyperglycemia | Covid19

Mexico
Sana Klinikum Offenbach

Completed

Preoperative Condition in Giant Obese Patients

Morbid Obesity | Bariatric Surgery Candidate

Germany
Claus Bogh Juhl

Completed

Effects of Liraglutide in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Denmark
University Hospital, Gentofte, Copenhagen

Completed

GA 6: The Blood Glucose-lowering Effect of Glucose-dependent Insulinotropic Polypeptide

Type2 Diabetes

Denmark
RWTH Aachen University
Novo Nordisk A/S

Withdrawn

Effect of Liraglutide on the Metabolic Profile in Patients With Type 2 Diabetes and Cardiovascular Disease (Lirabolic)

Cardiovascular Diseases | Type 2 Diabetes

Germany
Centre Hospitalier Universitaire de Besancon
Eli Lilly and Company; AstraZeneca

Completed

Impact of Perioperative Exenatide Infusion on Quality of Life in Cardiac Surgery Patients (ExeQOL)

Quality of Life

France

Search clinical trials for: incretin effect

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Poland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations