Search clinical trials for: pragmatic clinical trial

Total 82086 results

Ain Shams University

Recruiting

The Adjunctive Role of Vitamin C on Pigment Recurrence (Randomized Clinical and Histological Trial)

Gingival Pigmentation

Egypt
Le Yu

Recruiting

Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial

Anesthesia

China
Eli Lilly and Company

Recruiting

A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943

Obesity

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

DP303c Versus Trastuzumab Emtansine in in Patients With HER2-positive Advanced Breast Cancer

HER2-positive Breast Cancer

China
DICE Therapeutics, Inc., a wholly owned subsidiary...
Eli Lilly and Company

Recruiting

A Study to Evaluate Safety, Tolerability of LY4100511 (DC-853) in Healthy Asian and Non-Asian Participants

Healthy

United States
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Non Small Cell Lung Cancer

United States, Israel, Taiwan, Korea, Republic of, Switzerland, Hong Kong
ViiV Healthcare

Recruiting

A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants

HIV Infections

United States
Riphah International University

Recruiting

Combined Effects of Virtual Reality and Motor Imagery Techniques With Routine Physical Therapy in Post Stroke Patients

Stroke

Pakistan
Zhejiang Cancer Hospital

Not yet recruiting

Eribulin Combined With Sintilimab as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Breast Cancer:A Multicenter, Single-arm,Phase II Clinical Trial

Metastatic Breast Cancer

China
Riphah International University

Recruiting

Comparative Effects of Mime Therapy and Action Observation Therapy in Bell's Palsy

Bell Palsy

Pakistan
Intuitive Surgical
Intuitive Surgical-Fosun Medical Technology (Shanghai) Co., Ltd

Recruiting

A Trial to Compare Robotic Assisted Bronchoscopy Ion's Clinical Utility for Peripheral Lung Nodule Access and Diagnosis to ENB (ARTICULAtE)

Lung Cancer | Pulmonary Nodule, Solitary

China
Boehringer Ingelheim

Recruiting

A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight

Obesity | Non-Alcoholic SteatoHepatitis (NASH)

United States
Usona Institute
Worldwide Clinical Trials

Recruiting

Psilocybin for Major Depressive Disorder (MDD) (uAspire)

Depressive Disorder, Major

United States
Riphah International University

Recruiting

Comparison of Modified-Otago and Tai Chi Exercises in Patients With Stroke

Stroke

Pakistan
Riphah International University

Recruiting

Effects of Resisted Versus Balance Exercises on Cognitive And Motor Function In Patients With Mild Cognitive Impairment

Mild Cognitive Impairment

Pakistan
Carsten Dirksen
University of Copenhagen; University of Oxford; University of Bristol; University... and other collaborators

Recruiting

Intensive Weight Loss Intervention Versus Bariatric Surgery for Adults With Severe and Complex Obesity: the LightBAR Randomised Trial (LightBAR)

Obesity

United Kingdom, Denmark
argenx

Recruiting

A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease. (UplighTED)

Thyroid Eye Disease

United States
Chengdu CoenBiotech Co., Ltd
Jiangsu Province Centers for Disease Control and Prevention; Changde First... and other collaborators

Recruiting

Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old.

Tuberculosis

China
Rady Pediatric Genomics & Systems Medicine Institute

Recruiting

An Adaptive Clinical Trial of BeginNGS Newborn Screening for Hundreds of Genetic Diseases by Genome Sequencing (BeginNGS)

Genetic Disease

United States
Mayo Clinic

Recruiting

Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Medical College of Wisconsin

Not yet recruiting

Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X)

Non Small Cell Lung Cancer

United States
Merck Sharp & Dohme LLC
ModernaTX, Inc.

Recruiting

A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004)

Renal Cell Carcinoma

Australia, United States, Canada, Chile, Taiwan, Argentina
Post Graduate Institute of Medical Education and...

Not yet recruiting

Intravenous Methylene Blue for Treating Refractory Neonatal Septic Shock

Shock, Septic | Neonatal Sepsis

India
RenJi Hospital

Not yet recruiting

A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis

Decompensated Cirrhosis
Instituto de Investigación Hospital Universitario...

Not yet recruiting

Assessing Interest in Web/App Platforms for Early Phase Clinical Trial Recruitment

Assessing Interest in a Platform for Early Phase Clinical Trial Recruitment
4th Military Clinical Hospital with Polyclinic,...

Recruiting

CardioPROTECTion With Dapagliflozin in Breast Cancer Patients Treated With AnthrAcycline - PROTECTAA TRIAL (PROTECTAA)

Heart Failure | Breast Cancer

Poland
University of Seville

Recruiting

Differents Laser Applications on Plantar Fasciitis

Fasciitis, Plantar

Spain
NEUROPHET
Pusan National University Yangsan Hospital; Saint Vincent's Hospital, Korea; Bucheon... and other collaborators

Recruiting

Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Function in Patients With Post-Stroke Dysphagia

Deglutition Disorders

Korea, Republic of
Merck Sharp & Dohme LLC
ModernaTX, Inc.

Recruiting

A Study of Pembrolizumab (MK-3475) Plus V940 in Participants With Bladder Cancer Post-Radical Resection (V940-005)

Bladder Cancer

Canada, New Zealand, Germany, Chile, Australia, United States, Poland, Spain, Sweden, France, Italy
Riphah International University

Not yet recruiting

Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation in Erb's Palsy

Erb's Palsy

Pakistan
Abbisko Therapeutics Co, Ltd

Recruiting

A Clinical Trial to Evaluate the Relative Bioavailability of New and Old ABSK-011 Capsules

Healthy Subjects

China
Changi General Hospital

Not yet recruiting

Elevated Lipoprotein(a) in Hospital Staff (LPACO)

Cardiovascular Diseases | Hypercholesterolemia | Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia

Singapore
Peking University

Not yet recruiting

County Medical Community-based, Cardiovascular Risk Stratified Integrated Care Model: a Pragmatic Cluster Randomised Control Trial (RISIMA)

Cardiovascular Diseases | Hypertension | Diabetes Mellitus Type 2
Jie Li

Recruiting

A Clinical Trial to Evaluate the Time Point of Anti-VEGF Pretreatment of PDR Based on Intraoperative FFA

The Condition of Fundus Neovascularization

China
Inimmune Corporation
Avance Clinical Pty Ltd.

Not yet recruiting

Trial of INI-4001 in Patients With Advanced Solid Tumours

Advanced Solid Tumor

Australia
Tor Biering-Sørensen

Not yet recruiting

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease (NUDGE-CKD)

Chronic Kidney Diseases | Behavior and Behavior Mechanisms

Denmark
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Efficacy of Combination of Hdroxyurea and Thalidomide Over Either Hydroxyurea or Thalidomide Alone in the Treatment of Transfusion Dependent Thalassemia in Children: A Quasi-Randomised Clinical Trial

Transfusion-dependent Thalassemia

Bangladesh
Vanderbilt University Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment

Interstitial Cystitis | Cystitis, Interstitial | Painful Bladder Syndrome | Chronic Prostatitis With Chronic Pelvic Pain Syndrome | Chronic Prostatitis | Bladder Pain Syndrome | Chronic Interstitial Cystitis | Interstitial Cystitis, Chronic | Cystitis, Chronic Interstitial | Interstitial Cystitis (Chronic)... and other conditions

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host Disease

Chronic Graft Versus Host Disease

China
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC) (ROXI-CATH)

Venous Thromboembolism
Shanghai Institute Of Biological Products
The First Affiliated Hospital of Henan University of Science and Technology; First Affiliated Hospital Bengbu Medical College and other collaborators

Recruiting

A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.

Gout

China
Assiut University

Not yet recruiting

The Utility of Mobile Based Application for Patient Reported Outcome Measures In Patients With Acetabular Fractures : A Randomized Clinical Trial

Acetabular Fracture
Centre for Addiction and Mental Health

Not yet recruiting

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD (PAP-OCD)

Obsessive-Compulsive Disorder
Eli Lilly and Company

Not yet recruiting

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

Alzheimer Disease

United States, United Kingdom, Japan
Eli Lilly and Company

Recruiting

A Study of LY3841136 in Japanese Participants With Obesity or Overweight

Obesity | Overweight

Japan
Shanghai Institute Of Biological Products
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

A Clinical Trial of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients.

Advanced Solid Tumor
Intra-Cellular Therapies, Inc.

Recruiting

PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects

Healthy Volunteers

United States
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Type 2 Diabetes

United States, Argentina, United Kingdom, Puerto Rico
Omeros Corporation

Recruiting

Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

Switzerland, Germany, Ukraine, United Kingdom
Spark Therapeutics, Inc.

Recruiting

Study of a Gene Therapy Treatment for Hemophilia A (KEYSTONE 1)

Hemophilia A

United States

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