Search clinical trials for: purine

Total 2137 results

SFJ Pharmaceuticals, Inc.
SFJ Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Safety, Tolerability, PK, and PD of PB2452 With and Without Ticagrelor Pretreatment in Chinese Healthy Volunteers

Healthy

China
The TIMI Study Group

Completed

Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial (COVID-PACT)

COVID-19 | Venous Thromboembolism | Arterial Thrombosis

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Suspended

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | Recurrent Acute Lymphoblastic... and other conditions

United States
St. Jude Children's Research Hospital
Baylor College of Medicine; Gateway for Cancer Research

Active, not recruiting

Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I

Acute Lymphoblastic Leukemia

United States, Canada
Washington University School of Medicine
National Cancer Institute (NCI); American Society of Clinical Oncology; ImmunityBio... and other collaborators

Terminated

Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Leukemia, Myeloid, Acute

United States
Ottawa Heart Institute Research Corporation

Suspended

Personalization of Long-Term Antiplatelet Therapy - RAPID EXTEND (RAPID EXTEND)

Myocardial Infarction | Coronary Artery Disease

Canada
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Acute Undifferentiated Leukemia | Childhood T Acute Lymphoblastic Leukemia

United States, Canada, Australia, New Zealand
University of New Mexico
Pfizer

Terminated

Caffeine Reduction and Overactive Bladder Symptoms

Overactive Bladder

United States
Massachusetts General Hospital

Completed

Helping Olfaction and Nutrition On Renal Replacement (HONORR)

End Stage Renal Disease | Olfactory Disorders

United States
University of Vic - Central University of Catalonia
European Union; Generalitat de Catalunya

Completed

Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects

Fatigue | Physical Activity | Injuries | Caffeine | Biomechanics

Spain
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Hodgkin Lymphoma | Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Myeloproliferative... and other conditions

United States
Lu Jiang

Completed

Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)

Caffeine | Burning Mouth Syndrome

China
ViiV Healthcare

Completed

Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults

HIV Infections

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic... and other conditions

United States
LG Chem

Completed

Effect of Tigulixostat on the Pharmacokinetics of Theophylline

Hyperuricemia | Gout

United States
Kafrelsheikh University

Completed

Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke

Ischemic Stroke

Egypt
University of Miami
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD

COPD | COPD Exacerbation | Pollution; Exposure | COPD Exacerbation Acute | Pollution Related Respiratory Disorder

Uganda
University of Wisconsin, Madison

Completed

The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope

Syncope, Vasovagal

United States
M.D. Anderson Cancer Center

Active, not recruiting

Ibrutinib, Fludarabine Phosphate, Cyclophosphamide, and Obinutuzumab in Treating Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
University of Alabama at Birmingham

Completed

Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine

Pregnancy Related | Headache | Occipital Nerve Block

United States
Seung-Jung Park
CardioVascular Research Foundation, Korea

Active, not recruiting

Optimal Duration of Antiplatelet Therapy After Bioresorbable Vascular Scaffold Implantation to Reduce Late Coronary Arterial Thrombotic Events (BVS LATE)

Coronary Disease | Percutaneous Transluminal Coronary Angioplasty

Korea, Republic of
AstraZeneca

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AZD3366 in Healthy Subjects, Japanese and Chinese Subjects

Cardiovascular Disease

United States
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States, Canada, Israel, Puerto Rico
Spaulding Rehabilitation Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury

Spinal Cord Injuries

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis

Primary Myelofibrosis | Secondary Myelofibrosis

United States
Inova Health Care Services

Terminated

Antiplatelet Effects of Tirofiban vs. Cangrelor N-STEMI Patients Undergoing Percutaneous Coronary Intervention

Non-ST Elevation Myocardial Infarction (NSTEMI)

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

8-Chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate BMS-986141 Added on to Aspirin or Ticagrelor or the Combination, on Thrombus Formation in a Thrombosis Chamber Model in Participants With Stable Coronary Artery Disease and Healthy Participants

Coronary Artery Disease | Healthy Participants

United Kingdom
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Clopidogrel Film-coated Tablets 75 mg in Healthy Male Subjects Under Fasting Conditions

Bioequivalence

Russian Federation
University of South Carolina

Completed

Improving Cognition With Neurodegradation Countermeasure

Cognitive Change | Caffeine | Hemodynamics | TeaCrine

United States
Georgetown University
Kyowa Kirin, Inc.

Active, not recruiting

Istradefylline Effect Protocol on Parkinson's Disease Tremor

Parkinson Disease | Tremor

United States
Seoul St. Mary's Hospital

Completed

Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes

Apnea of Prematurity | Caffeine | Preterm

Korea, Republic of
Xijing Hospital

Active, not recruiting

1-month DAPT Plus 5-month Ticagrelor Monotherapy Versus 12-month DAPT in Patients With Drug-coated Balloon (CAGEFREEII)

Acute Coronary Syndrome | Angioplasty, Balloon | Antiplatelet Drug

China
National Taiwan University Hospital
National Taiwan University Hospital, Yun-Lin Branch

Terminated

Low-dose Colchicine With or Without Stepwise Dose Titration of Febuxostat for Flare Prophylaxis in Gout

Gout

Taiwan
Abbott Medical Devices
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Baim Institute...

Completed

XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort (XVU-AV DAPT)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Vascular Disease | Coronary Artery Stenosis

United States
The First Affiliated Hospital of Zhengzhou University
General Hospital of Shenyang Military Region; Beijing Tiantan Hospital; Shanghai...

Completed

Thrombolysis of Urokinase for Minor Stroke (TRUST)

Minor Stroke

China
Yonsei University

Active, not recruiting

A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients; A-CLOSE Trial

Coronary Artery Disease | DES

Korea, Republic of
Riphah International University

Completed

Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.

Muscle Damage

Pakistan
Iovate Health Sciences International Inc
Citruslabs

Completed

Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus

Caffeine Withdrawal | Energy | Focus

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Erythroid Leukemia | Acute Megakaryoblastic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Blast Phase Chronic Myelogenous Leukemia,... and other conditions

United States
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Completed

Ticagrelor Compared to Clopidogrel in Acute Coronary Syndromes (TC4)

Acute Coronary Syndrome

Canada
Jiangsu vcare pharmaceutical technology co., LTD

Completed

PK/PD Study of Vicagrel and Clopidogrel in Healthy Subjects With Different CYP2C19 Metabolizers

Acute Coronary Syndrome

United States, China
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Acute Myeloid Leukemia | Down Syndrome | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myeloid Leukemia Associated With Down Syndrome

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
Zagazig University

Completed

Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin

Analgesia

Egypt
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants

Healthy Volunteers

United States
Rutgers, The State University of New Jersey
Amgen

Terminated

Pilot Study Evaluating The Efficacy Of Etanercept In Acute Gout

Gout Attack

United States
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor (RAPID CABG)

Acute Coronary Syndrome

Canada
NYU Langone Health

Active, not recruiting

Study of the Safety and Efficacy of a Caffeine-based Antifibrosis Cream in Patients With Breast Cancer Undergoing Radiation Therapy (ReDCoAT)

Carcinoma Breast

United States
Al-Azhar University

Active, not recruiting

the Incidence of Necrotizing Enterocolitis in Preterm With Respiratory Distress Syndrome Undergoing Caffeine Therapy

Pharmacological Action of Drug

Egypt
Mazandaran University of Medical Sciences

Completed

Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke (TACAMINIS)

Ischemic Stroke | Transient Ischemic Attack

Iran, Islamic Republic of

Search clinical trials for: purine

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