Search clinical trials for: randomized phase II

Total 53450 results

QLT Inc.

Terminated

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of Tariquidar + Vinorelbine as First-Line Therapy in Non-Small Cell Lung Cancer (NSCLC)

Stage IV Non-small Cell Lung Cancer | Stage IIIb Non-small Cell Lung Cancer
University of Kentucky
Bayer

Terminated

Randomized Phase III Trial of Leukine® vs Neupogen® in Patients Receiving Cisplatin & Gemcitabine for Urothelial Cancer

Bladder Cancer

United States
National Cancer Institute, Naples

Completed

CALC-1 (Cetuximab in Advanced Lung Cancer): Study of 2 Methods of Combining Cetuximab and Gemcitabine in Patients With Advanced Non Small-cell Lung Cancer (CALC-1)

Advanced Non-Small Cell Lung Cancer

Italy
Windtree Therapeutics

Terminated

Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration Syndrome

Meconium Aspiration

United States
Crucell Holland BV

Completed

Randomized Phase II Trial on Safety and Neutralizing Activity of CL184 and Rabies Vaccine Versus Human Rabies Immune Globulin (HRIG) and Rabies Vaccine in Children and Adolescents

Rabies

Philippines
Mast Therapeutics, Inc.
CytRx

Completed

Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease

Sickle Cell Anemia
Asan Medical Center

Completed

Randomized Phase II Study of FOLFOX Versus FOLFIRI.3 in Gemcitabine-refractory Pancreatic Cancer

Metastatic Pancreatic Cancer

Korea, Republic of
Samsung Medical Center

Completed

Phase III Randomized Trial of Adjuvant XP Chemotherapy and XP/RT for Resected Gastric Adenocarcinoma

Gastric Cancer | Surgery

Korea, Republic of
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); American Thoracic Society; American Society for Parenteral and Enteral Nutrition and other collaborators

Completed

A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI)

Acute Respiratory Distress Syndrome | Acute Lung Injury | Respiratory Distress Syndrome, Adult

United States, Canada
New Mexico Cancer Care Alliance

Completed

A Phase III Randomized Trial Assessing the Utility of a Test Dose Program With Taxanes

Supportive | Ill-defined Sites

United States
Crucell Holland BV

Completed

A Randomized Phase II Trial to Compare the Safety and Neutralizing Activity of CL184 in Combination With Rabies Vaccine vs. HRIG or Placebo in Combination With Rabies Vaccine in Healthy Adult Subjects

Rabies

United States
Stem Cell Therapeutics Corp.

Withdrawn

REGENESIS (US): A Phase IIb Prospective, Randomized, Double-blind, Placebo Controlled Study of NTx™-265: Human Chorionic Gonadotropin (hCG) and Epoetin Alfa (EPO) in Acute Ischemic Stroke Patients (REGENESIS)

Stroke

United States
UCB Pharma

Completed

Randomized Phase III Study to Evaluate the Efficacy and Safety of Xyzal® (Levocetirizine) vs Zyrtec® (Cetirizine) in Subjects With Dermatitis and Eczema

Dermatitis | Eczema

Korea, Republic of
Taiho Pharmaceutical Co., Ltd.

Completed

Randomized Phase III Study of TS-1 Alone Versus TS-1 Plus CDDP in Advanced Gastric Cancer

Gastric Cancer

Japan
Central European Cooperative Oncology Group

Completed

An Open, Randomized, Multicentre, Phase II Pilot Study

Non-Small Cell Lung Cancer
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C213: A Phase II Randomized, Controlled, Partially Blinded Trial to Investigate Dose-response of TMC114/RTV in 3-class-experienced HIV-1 Infected Patients, Followed by an Open-label Period on the Recommended Dose of TMC114/RTV.

HIV
Allergan

Completed

A Phase II, Randomized Study of ACZONE™ (Dapsone) Gel, 5% for Papulopustular Rosacea.

Rosacea

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C227: A Phase II Randomized, Active-Controlled, Open Label Trial to Investigate the Efficacy and Tolerability of TMC125 in HIV-1 Infected Subjects, Who Are PI-Naive and With Documented Genotypic Evidence of NNRTI Resistance From Previous NNRTI Use

HIV Infection
Bristol-Myers Squibb

Completed

Phase II Randomized, Double-Blind, Placebo-Controlled Study of BMS-188667 (CTLA4Ig) in Patients With Psoriasis Vulgaris

Psoriasis Vulgaris

United States
QLT Inc.

Terminated

A Phase II, Randomized, Cross-Over, Vehicle-Controlled, Double-Blind, Multicenter Study of the Safety, Pharmacodynamics, and Preliminary Efficacy of GHRP-1/AG in Subjects With ESRD on Hemodialysis

End Stage Renal Disease

United States
King Faisal Specialist Hospital & Research Center

Suspended

Randomized Phase III Trial of Surgery Alone or Surgery Plus Preoperative Gemcitabine-Cisplatin in Clinical Early Stages of Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung
Memorial Sloan Kettering Cancer Center

Completed

Acupuncture for the Treatment of Chronic Post-Chemotherapy Fatigue: A Randomized, Phase III Trial

Cancer

United States
Karolinska Institutet
Merck Sharp & Dohme LLC

Completed

Nordic Adjuvant IFN Melanoma Trial

Melanoma | Adjuvant Therapy

Sweden
Lotus Pharmaceutical

Unknown

A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus

The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg | Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks in | Subjects With Type 2 Diabetes Mellitus.

Taiwan
MedImmune LLC

Completed

A Phase II Randomized, Double-Blind, Two-Period Cross-Over Study to Evaluate the Pharmacokinetics, Safety and Tolerability of a Liquid Formulation of Palizvizumab (MEDI-493, Synagis)

-Unhealthy Children With a History of Prematurity

United States
Antisoma Research

Unknown

Phase III Randomized Study of Amonafide (AS1413) and Cytarabine Versus Daunorubicin and Cytarabine in Patients With Secondary Acute Myeloid Leukemia (AML)- the ACCEDE Study

Secondary Acute Myeloid Leukemia (Secondary AML, sAML)

Korea, Republic of, United States, Spain, United Kingdom, Australia, Austria, Taiwan, Israel, Italy, Belgium, Germany, France, Romania, Estonia, Canada, Ukraine, Ecuador, Hungary, Poland, Chile, Argentina, Czech Republic, Russian Federation
Mayo Clinic

Completed

Phase II Randomized Study of Muromonab-CD3, Cyclosporine, Methylprednisolone, and Prednisone in Patients With Giant Cell Myocarditis

Myocarditis | Giant Cell Myocarditis

United States
Hadassah Medical Organization
Augusta Hospital, Berlin

Completed

Initial Assessment of the Effect of the Addition of Disulfiram (Antabuse) to Standard Chemotherapy in Lung Cancer

Non-small Cell Lung Cancer

Israel
Capnia, Inc.

Completed

The Effect of Nasal Carbon Dioxide (CO2) in the Treatment of Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Phase III Study of Folfiri+Avastin Versus Xeliri+Avastin as 1st Line Treatment of CRC

Colorectal Cancer

Greece
Samsung Medical Center

Unknown

A Randomized Phase II Study of Concurrent Chemoradiation With Every 3 Week of Cisplatin vs With Weekly Cisplatin in Locally Advanced Nasopharyngeal Carcinoma

Nasophayngeal Carcinoma Between Stage II and IVb

Korea, Republic of
BioLineRx, Ltd.

Completed

A Six-week, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center, Phase II Study

Schizophrenia

United States
Tel-Aviv Sourasky Medical Center

Unknown

The Impact of Patient Positioning and Use of Belly Board on Small Bowel and Urinary Bladder Volume Irradiated in Patients Receiving Radiotherapy for Rectal Cancer: A Prospective Phase II Study

Rectal Cancer

Israel
Hokkaido Gastrointestinal Cancer Study Group
Hokkaido University Hospital

Unknown

Randomized Phase III Adjuvant Study for Stage III Colorectal Cancer

Colorectal Cancer

Japan
Cifarma Cientifica Farmaceutica Ltda

Unknown

Clinical Study Phase III, Randomized, Double-blind, Prospective and Comparative to Evaluate the Efficacy and Tolerability of Using APETIVITON BC Compared to Petivit BC in Appetite Stimulate. (Apetiviton BC)

Inappetence
Intergroupe Francophone de Cancerologie Thoracique
Sanofi; AstraZeneca

Completed

Randomized Phase 2 Study of 3 Therapeutic Modalities in PS 2/3 Patients With NSCLC Stage IIIB/IV

Carcinoma, Non-Small-Cell Lung

France
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients

HIV-1 | Anti-Retroviral Agents
Eli Lilly and Company
Memorial Sloan Kettering Cancer Center; Merck KGaA, Darmstadt, Germany; US Department... and other collaborators

Completed

Survival in a Randomized Phase III Trial in Patients With Limited Disease (LD) Small Cell Lung Cancer Vaccinated With Adjuvant BEC2 and BCG

Carcinoma, Small Cell Lung
Moberg Pharma AB

Completed

Assessment of the Effects on Barrier Impairment, Clinical Features and Bacterial Colonization of Topical Formulations in Patients With Atopic Eczema; a Phase IIa, Single-center, Randomized, Observer-blind Study

Atopic Dermatitis

Germany
Pfizer

Terminated

Randomized Ph 2 Trial Of Paclitaxel/Carboplatin /Bevacizumab + PF-3512676 And P/C/B Alone In Advanced Nonsquamous NSCLC

Carcinoma, Non-Small-Cell Lung

United States
Laboratorios Osorio de Moraes Ltda.

Unknown

Phase III Open Study, Prospective, Multicenter, Randomized, Comparative to the Positive Control for Evaluating the Efficacy and Safety of Auris-Sedina in the Symptomatic Control of Otalgy in Patients With or Without Acute External Otitis. (E02OSMAS0108)

Otitis | Efficacy | Tolerability

Brazil
National Health Research Institutes, Taiwan
Novartis

Unknown

Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

Taiwan
Procter and Gamble

Terminated

Phase II, Randomized, Placebo-Controlled Study of ATI-7505 in Patients With Chronic Idiopathic Constipation

Chronic Constipation

United States, Canada
Ever Neuro Pharma GmbH
acromion GmbH

Completed

Comparative Study to Test Safety and Efficacy of Neurotrophic and Cholinergic Treatment of Alzheimer's Disease (Combi)

Alzheimer Disease

Spain
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Phase III Trial With Docetaxel Plus Epirubicine Versus Docetaxel Plus Capecitabine for Metastatic Breast Cancer

Breast Cancer

Greece
National Institute of Cancerología
Psicofarma S.A. de C.V.

Unknown

Hydralazine Valproate for Cervical Cancer

Metastatic Cervical Cancer

Mexico
Assistance Publique - Hôpitaux de Paris
ARTIC group (oncologists and urologists association)

Unknown

A Prospective Randomized Phase III Study Comparing Hormonal Therapy +/-Docetaxel (RisingPSA)

Adenocarcinoma of the Prostate

France
Eunice Kennedy Shriver National Institute of Child...
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)

HIV Infections | Pregnancy

United States, Puerto Rico
National Institute of Diabetes and Digestive and...
University of Pittsburgh

Completed

Phase I/II Randomized, Placebo-Controlled Study of Capsaicin for Interstitial Cystitis and Vulvar Vestibulitis

Vulvar Diseases | Interstitial Cystitis
National Institute of Neurological Disorders and...
Mayo Clinic

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Immune Globulin for Multiple Sclerosis

Multiple Sclerosis

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