Search clinical trials for: substance

Total 15248 results

Institute of Liver and Biliary Sciences, India

Not yet recruiting

Role of Extended Low Dose Prednisolone in Achieving Clinical and Biochemical Remission in Steroid Responsive Severe Alcoholic Hepatitis

Severe Alcoholic Hepatitis

India
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
Tongji Hospital

Recruiting

Pyrotinib Combined With Capecitabine and Bevacizumab for Patients With HER2 Positive Breast Cancer and Brain Metastases

Breast Cancer With Brain Metastases

China
Henrik Lindman

Recruiting

Effect of Salovum™ and SPC-Flakes™ on Abemaciclib-induced Gastrointestinal Toxicity in Early Breast Cancer (ASF-BC)

Diarrhea | Adverse Drug Event | Early-stage Breast Cancer

Sweden
Pfizer

Recruiting

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Multiple Myeloma

United States, Japan, Norway, Spain, Sweden, Canada, Belgium, France, Germany, Brazil, Finland, Argentina, Czechia
Sohag University

Not yet recruiting

Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals

Acute Hydrocarbon Toxicity

Egypt
The First Affiliated Hospital of Xiamen University
The First Affiliated Hospital with Nanjing Medical University; Sun Yat-sen... and other collaborators

Recruiting

Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL

Follicular Lymphoma | DLBCL - Diffuse Large B Cell Lymphoma

China
CapSoil

Recruiting

Comparative PK Study Of THC/CBD Formulations

Cannabis

Israel
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Participants With Follicular Lymphoma and Marginal Zone Lymphoma (OLYMPIA-5)

Relapsed/Refractory Follicular Lymphoma | Marginal Zone Lymphoma (MZL)

Italy, Korea, Republic of, Australia, France, Spain, Malaysia, Taiwan, Poland, United States, United Kingdom, Turkey, Belgium, Thailand, Czechia
Kinnov Therapeutics

Not yet recruiting

A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine

Alcohol Use Disorder
Shanghai Mental Health Center

Recruiting

Treatment Effect of Cross-frequency Transcranial Alternating Current Stimulation on the MUD

Amphetamine-Related Disorders

China
University Hospital, Clermont-Ferrand

Recruiting

Diffusion Tensor Brain MRI in the Detection of Structural Abnormality of the White Substance in Concussion (COMMOTION)

Concussion, Brain

France
M.D. Anderson Cancer Center

Recruiting

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

Neurotoxicity

United States
Lauren Whitehurst
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Ohio State University

Recruiting

The Effects of Sex Hormones and Alcohol on Sleep

Alcohol Use Disorder

United States
Wuhan Union Hospital, China

Recruiting

Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma

Multiple Myeloma | Extramedullary Multiple Myeloma | Primary Plasma Cell Leukemia

China
Dartmouth-Hitchcock Medical Center

Not yet recruiting

A Study of Tetrathiomolybdate (TM) Plus Capecitabine

Triple Negative Breast Cancer | Residual Disease
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers

Alcohol Consumption | Alcohol Use Disorder (AUD) | Heavy Drinker

United States
Western Michigan University
National Institute on Drug Abuse (NIDA); RTI International; DynamiCare Health...

Recruiting

OUD Smartphone Services

Opioid-Related Disorders | Drug Abuse

United States
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Not yet recruiting

A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors

Advanced Solid Tumor

China
University of Kentucky

Not yet recruiting

Cannabis for Obesity Trial

Obesity
Rush University Medical Center

Recruiting

Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

Alcohol Use Disorder | Human Immunodeficiency Virus

United States
University of Pennsylvania

Recruiting

Integrating Brain, Neurocognitive, and Computational Tools in OUD

Opioid Use Disorder

United States
Portland VA Medical Center

Recruiting

Compensatory Cognitive Training Via Telehealth for Veterans With Alcohol Use Disorders (CCT-A)

Alcohol Use Disorder

United States
West China Second University Hospital

Recruiting

Cardiac Magnetic Resonance Monitoring of Immune Checkpoint Inhibitor-related Cardiotoxicity

Immune Checkpoint Inhibitors, Cardiotoxicity

China
Chang Gung Memorial Hospital

Recruiting

Atezolizumab and Bevacizumab With Proton Radiotherapy for Unresectable Hepatocellular Carcinoma (ProtonAB)

Hepatocellular Carcinoma Non-resectable

Taiwan
Caregen Co. Ltd.
CBCC Global Research

Not yet recruiting

Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration

Age-related Wet Macular Degeneration

United States
Western University, Canada

Not yet recruiting

Nutritional Interventions in Patients With Alcohol-associated Hepatitis

Alcoholic Hepatitis
University of Cincinnati
Spark Biomedical, Inc.

Recruiting

tAN for PTSD and OUD in Buprenorphine Therapy

Opioid Use Disorder | Posttraumatic Stress Disorder

United States
PATH
London School of Hygiene and Tropical Medicine; Monash University; University... and other collaborators

Not yet recruiting

Assessing the Acceptability, Feasibility, Effectiveness and Cost-effectiveness of LADB

Opioid Dependence
Edith Nourse Rogers Memorial Veterans Hospital
US Department of Veterans Affairs

Not yet recruiting

Utilizing Battlefield Acupuncture to Treat Chronic Pain

Chronic Pain | Substance Use Disorders

United States
Bio-Thera Solutions

Not yet recruiting

BAT1308 Combined With Platinum-Based Chemotherapy± Bevacizumab For PDL1-Positive (CPS ≥1) Cervical Cancer

Cervical Cancer

China
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Evaluation of the Efficacy and Safety of Bevacizumab Combined With PD-1 Monoclonal Antibody in Preoperative Neoadjuvant Therapy for MSS Colorectal Cancer With Liver Metastases

Colorectal Cancer
Huihua Xiong

Recruiting

The Efficacy and Safety of Utidelone Plus Tirelizumab and Bevacizumab for Advanced or Metastatic Triple-negative Breast Cancer (UTILIZABLE) ：Single-arm, Prospective, Open Clinical Study (UTILIZABLE)

TNBC - Triple-Negative Breast Cancer

China
Assiut University

Not yet recruiting

Pattern of Acute Antipsychotic Drug- Toxicity in Children

Antipsychotic Drug- Toxicity
Dr. med. Marcus Herdener
University of Zurich; University of Vienna; University of Campania "Luigi Vanvitelli...

Recruiting

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction (Co-Boost)

Cocaine Use Disorder | Cocaine Dependence

Switzerland
University of Minnesota

Recruiting

Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)

Cannabis Use Disorder

United States
Kasr El Aini Hospital

Recruiting

Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events

Tonsillectomy | Adenoidectomy | Drug-Related Side Effects and Adverse Reaction

Egypt
Saint Thomas Hospital, Panama

Not yet recruiting

Angiogenic Factors in the Conservative Management of Gestational Hypertension

Gestational Hypertension
Henry Ford Health System
Michigan State University; University of Kansas; Detroit Recovery Project INC

Recruiting

Peer-Delivered Episodic Future Thinking for Returning Citizens

Behavior, Health

United States
University of Bern
Universität Luzern

Recruiting

Study on Regulated Cannabis Sales in Pharmacies (SCRIPT)

Cannabis | Cannabis Use | Marijuana Smoking

Switzerland
Bayer

Recruiting

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery (REFINE-IO)

Unresectable Hepatocellular Carcinoma

Greece, Spain, Brazil, China, Colombia, Italy, Saudi Arabia, Taiwan, Thailand, United States, Korea, Republic of, Argentina, France, Mexico, Turkey
Shanghai Juncell Therapeutics

Recruiting

A Phase Ⅰb Study on Autologous GC101 TIL Injection for the Treatment of Advanced Melanoma (MIZAR-002) (MIZAR-002)

Melanoma | Efficacy | Adverse Drug Event | Safety | Tumor Infiltrating Lymphocytes

China
Peng Zhang

Recruiting

Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

China
University of Massachusetts, Worcester
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

A Female-Specific CBT Group for Veteran Women With Alcohol Use Disorder in VA Primary Care Settings

Alcohol Use Disorder | Risky Health Behavior

United States
Ohio State University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Neural Correlates During Alcohol Intoxication

Alcohol Use Disorder | Intermittent Explosive Disorder

United States
Mario Negri Institute for Pharmacological Research
AstraZeneca

Recruiting

First Line Treatment With Olaparib in Combination With Bevacizumab in HRD Positive Patients (IOLANTHE)

Carcinoma, Ovarian Epithelial

Italy
H. Lee Moffitt Cancer Center and Research Institute
Regeneron Pharmaceuticals; Genzyme, a Sanofi Company

Recruiting

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

Metastatic Uveal Melanoma

United States
Massachusetts General Hospital
Massachusetts Department of Health

Recruiting

A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students

Substance Use | Harm Reduction | Adolescent Behavior

United States
NYU Langone Health
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)

Substance Use

United States
Kyowa Kirin, Inc.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration (nAMD)

United States, Japan, Australia, Korea, Republic of

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