Clinical Trials Sponsored by BLFS Incorporate

Total 1226 results

Bausch & Lomb Incorporated

Completed

Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)

Drug Hypersensitivity

United States
Bausch & Lomb Incorporated

Completed

Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome

Dry Eye Syndromes

United States
Cook Group Incorporated

Completed

Zenith Low Profile AAA Endovascular Graft (ZLP) Clinical Study (ZLP)

Abdominal Aortic Aneurysm | Iliac Aneurysm | Aorto-iliac Aneurysm

Japan
Bausch & Lomb Incorporated

Completed

Evaluation of the Onset and Duration of Action of Bepotastine Besilate Ophthalmic Solution in Acute Allergic Conjunctivitis

Conjunctivitis, Allergic

United States
Bausch & Lomb Incorporated

Completed

Safety/Efficacy of Bromfenac Ophthalmic Solution for Ocular Inflammation and Pain Associated With Cataract Surgery

Pain | Inflammation

United States
Bausch & Lomb Incorporated

Completed

Efficacy and Safety Study of Bepotastine Besilate Ophthalmic Solution in Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Bausch & Lomb Incorporated

Completed

Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction

Cataract

Philippines
Vertex Pharmaceuticals Incorporated

Completed

A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, Belgium, Romania, Serbia, United States, Puerto Rico, Germany, Hungary, Russian Federation, Croatia
Gen-Probe, Incorporated

Completed

Clinical Evaluation of the APTIMA® HPV 16 18/45 Genotype Assay on the PANTHER® System

Human Papillomavirus Infection

United States
Cook Group Incorporated

Terminated

Zenith® LP Abdominal Aortic Aneurysm (AAA) Post-Market Registry

Abdominal Aortic Aneurysm | Aorto-iliac Aneurysm

Netherlands, United Kingdom, Germany, Norway, Austria, Ireland, Italy
Gen-Probe, Incorporated

Completed

Clinical Evaluation of the APTIMA® HPV Assay Using the PANTHER™ System

Human Papilloma Virus Infection

United States
Bausch & Lomb Incorporated

Completed

Efficacy of Besifloxacin Ophthalmic Suspension in the Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Bausch & Lomb Incorporated

Completed

Evaluation of a Multi-Purpose Solution

Contact Lens Solutions

United States
Bausch & Lomb Incorporated

Completed

Performance of Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution in a New Packaging Configuration

Comfort

United States
Bausch & Lomb Incorporated

Completed

Zylet vs TobraDex in Blepharokeratoconjunctivitis

Blepharokeratoconjunctivitis

United States
Bausch & Lomb Incorporated

Completed

Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After Topical Instillation

Healthy

United States
Bausch & Lomb Incorporated

Completed

Evaluation of the Safety & Effectiveness of the Bausch & Lomb AKREOS® TL Intraocular Lens

Cataract | Aphakia

Germany
Bausch & Lomb Incorporated

Withdrawn

A Study to Evaluate the Safety and Effectiveness of the 217z Laser With Zyoptix for Lasik

Astigmatism | Myopia
Bausch & Lomb Incorporated

Completed

Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implant vs Standardized Therapy

Non-infectious Uveitis
Bausch & Lomb Incorporated

Completed

Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implants

Noninfectious Posterior Uveitis

United States
Bausch & Lomb Incorporated

Completed

Pediatric Zylet Safety and Efficacy Study

Hordeolum | Chalazion

United States
Gen-Probe, Incorporated

Completed

APTIMA HPV 16 18/45 Genotype Assay on the TIGRIS DTS System in Women With ASC-US or Negative Pap Test Results (AHPV-GT)

Human Papillomavirus Infection

United States
Cook Group Incorporated

Completed

Malignant Obstruction ZILVER Against Routine Therapy (MOZART I)

Pancreatic Neoplasms | Biliary Tract Neoplasms | Jaundice, Obstructive

United States
Vertex Pharmaceuticals Incorporated

Completed

Trial of AVN-944 in Patients With Advanced Hematologic Malignancies

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Waldenstrom's Macroglobulinemia | Acute Leukemia | Chronic Leukemia

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-985 in Subjects With Chronic Hepatitis C

Chronic Hepatitis C

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-770 on Desipramine

In Development for Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

Drug-Drug Interaction Study of VCH-222 and Telaprevir in Healthy Subjects

Hepatitis C

New Zealand
Vertex Pharmaceuticals Incorporated

Completed

Single and Multiple Dose Escalation Study of VX-509 in Healthy Subjects

Healthy

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of Telaprevir in Subjects With Hepatic Impairment

Hepatic Insufficiency

United States
Biosynexus Incorporated
GlaxoSmithKline

Completed

Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity Study in VLBW Neonates of BSYX-A110 (N003)

Staphylococcal Sepsis

United States
Cook Group Incorporated

Completed

Study of IVC Filter Retrieval With the Günther Tulip Vena Cava Filter

Venous Thromboembolism | Pulmonary Embolism

United States
Vertex Pharmaceuticals Incorporated

Not yet recruiting

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older

Cystic Fibrosis
Vertex Pharmaceuticals Incorporated

Recruiting

A Microneurography Study of NaV1.8 Inhibition in Healthy Adults

Pain

United Kingdom
Audioptics Medical Incorporated

Not yet recruiting

Ossiview Normative Mobility Data Collection Protocol

Conductive Hearing Loss, Middle Ear
Bausch & Lomb Incorporated

Recruiting

Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens

Astigmatism

United States
Vertex Pharmaceuticals Incorporated

Not yet recruiting

Evaluation of Efficacy and Safety of a Single Dose of Exa-cel in Participants With Severe Sickle Cell Disease, βS/βC Genotype

Sickle Cell Disease
Vertex Pharmaceuticals Incorporated

Recruiting

Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age

Cystic Fibrosis

United Kingdom, Canada, Switzerland, Australia
Vertex Pharmaceuticals Incorporated

Recruiting

A Study to Evaluate Pharmacokinetics (PK) and Safety of Inaxaplin in Participants With Renal Impairment

Renal Impairment

United States
Tvardi Therapeutics, Incorporated

Recruiting

Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

United States
Bausch & Lomb Incorporated

Recruiting

Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without Astigmatism

Hyperopia

United States
DMF Medical Incorporated

Recruiting

A New and Innovative Method for CO2 Removal in Anesthetic Circuits: Replacing Chemical Granulate (memsorb)

Anesthesia

Canada
Vertex Pharmaceuticals Incorporated

Active, not recruiting

A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation and Strength of Suzetrigine

Pain

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulation of Vanzacaftor/Tezacaftor/Deutivacaftor(VNZ/TEZ/D-IVA)

Cystic Fibrosis

United States
Bausch & Lomb Incorporated

Completed

Evaluation of the Safety and Pharmacokinetics of Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Combination Ophthalmic Solution

Allergic Conjunctivitis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Relative Bioavailability and Food Effect of a VX-118 Tablet Formulation

Cystic Fibrosis

United States
Tvardi Therapeutics, Incorporated

Completed

Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer

Breast Cancer

United States
Bausch & Lomb Incorporated

Completed

A Study of B + L Ophthalmic Viscosurgical Device (OVD) CVisc50

Cataract

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes

Cystic Fibrosis

Canada, France, United Kingdom, Israel, Australia, Spain, Germany, Netherlands, Denmark, Switzerland
Cook Group Incorporated

Completed

Paclitaxel-coated Peripheral Stents Used in the Treatment of Femoropopliteal Stenoses (XPEDITE)

Peripheral Arterial Disease (PAD)

Germany, New Zealand
Bausch & Lomb Incorporated

Completed

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Allergic Conjunctivitis.

Allergic Conjunctivitis

United States

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