Clinical Trials Sponsored by Leadiant Biosciences, Inc.

Total 721 results

Evopoint Biosciences Inc.
Merck Sharp & Dohme LLC

Recruiting

Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)

Carcinoma | Cervical Cancer | Prostate Cancer | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Other Solid Tumors

China
Seoul National University Hospital
Ensol Biosciences, Inc.

Completed

To Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy Subjects

Healthy Subjects

Korea, Republic of
Quadriga Biosciences, Inc.
Novotech (Australia) Pty Limited

Completed

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Melanoma | Sarcoma | Kidney Cancer | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Astrocytoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Thymic Carcinoma | Lung Cancer | Prostate Cancer | Brain Cancer | Cholangiocarcinoma | Bladder Cancer | Liver Cancer | Brain Metastases | Tongue Cancer | Esophagus... and other conditions

Australia
UCB BIOSCIENCES, Inc.
R-Pharm

Terminated

The Long-term Safety and Efficacy of CDP6038 (Olokizumab) With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Japan, Korea, Republic of, Taiwan
University of Wisconsin, Madison
Cellectar Biosciences, Inc.

Terminated

Study of 124I-NM404 in Advanced Solid Malignancies

Triple Negative Breast, Prostate, Colorectal, Gastric, Ovarian, Pancreatic, Esophageal, Soft Tissue Sarcoma, and Head & Neck Cancer

United States
UCB BIOSCIENCES, Inc.
PPD; Parexel

Completed

A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta (CRIB)

Rheumatoid Arthritis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis | Axial Spondyloarthritis (AxSpA) | Non-radiographic Evidence-AxSpA

Netherlands, Switzerland, United States, France
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Terminated

TPI 287 in Patients With Recurrent Glioblastoma Multiforme

Brain Cancer

United States
ActivX Biosciences, Inc.
Kyorin Pharmaceutical Co.,Ltd

Completed

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of KRP-104 in Patients With Type 2 Diabetes Inadequately Controlled on Metformin Alone

Type 2 Diabetes

United States
Bassett Healthcare
Genentech, Inc.; Viroclinics Biosciences B.V.

Recruiting

COmbination Therapy With Baloxavir and Oseltamivir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1) (COMBO 1)

Influenza

United States
University of Missouri-Columbia
Sagimet Biosciences Inc.

Completed

Evaluation of 3-V Bioscience-2640 to Reduce de Novo Lipogenesis in Subjects With Characteristics of Metabolic Syndrome

Metabolic Syndrome

United States
Coherus Biosciences, Inc.
Daiichi Sankyo Co., Ltd.

Completed

Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA) (CHS-0214-02)

Rheumatoid Arthritis

United States, Spain, Israel, Belarus, Japan, Poland, Hungary, South Africa, Germany, Russian Federation, France, United Kingdom
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Terminated

Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

Brain Neoplasms | Central Nervous System Neoplasms

United States
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Terminated

A Phase I Study of TPI 287 - Temozolomide Combination in Melanoma

Melanoma

United States
Sun Yat-sen University
Cyttel Biosciences Inc.

Unknown

Prognostic and Dynamic Change of CTC Enumeration in Advanced NSCLC With Chemotherapy and Targeted Therapy

Non Small Cell Lung Cancer

China
M.D. Anderson Cancer Center
Cellectar Biosciences, Inc.

Withdrawn

NOV-002 in Myelodysplastic Syndrome (MDS)

Leukemia | Myelodysplastic Syndrome
Gulam Manji
Arcus Biosciences, Inc.

Recruiting

Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma (AIRPanc)

Pancreatic Ductal Adenocarcinoma

United States
Catherine Spina
Arcus Biosciences, Inc.

Recruiting

Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer (SBRT-AMICO)

Oligometastatic Prostate Cancer

United States
Cellectar Biosciences, Inc.
National Cancer Institute (NCI)

Recruiting

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

High-Grade Glioma

United States, Canada
Alzeca Biosciences, Inc.
pharmtrace klinische Entwicklung GmbH

Recruiting

Proof-of-concept Study of New Imaging Diagnostic in Patients With Suspected Alzheimer's Disease

Alzheimer Disease

Germany
Coherus Biosciences, Inc.
Merck Sharp & Dohme LLC

Recruiting

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

Clear Cell Renal Cell Carcinoma | Hepatocellular Carcinoma | Advanced Solid Tumor | Non-small Cell Lung Cancer

Korea, Republic of, United States, Singapore
Arcus Biosciences, Inc.
Gilead Sciences; Strata Oncology

Active, not recruiting

Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Jonsson Comprehensive Cancer Center
Arcus Biosciences, Inc.

Suspended

Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Borderline Resectable Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma

United States
UCB BIOSCIENCES, Inc.
R-Pharm

Terminated

Open-label Study to Assess the Safety and Efficacy of CDP6038 (Olokizumab) in Patients Who Completed RA0056

Rheumatoid Arthritis

United States, Belgium, United Kingdom
Calithera Biosciences, Inc
Novotech (Australia) Pty Limited

Completed

Impact of a Histamine H2 Receptor Antagonist (H2RA) on the Pharmacokinetics (PK) of Telaglenastat in Healthy Subjects

Drug Interaction

Australia
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Completed

TPI 287 in Breast Cancer Metastatic to the Brain

Breast Cancer

United States
UCB BIOSCIENCES, Inc.
PPD; Parexel

Completed

A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers (CRADLE)

Rheumatoid Arthritis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis | Axial Spondyloarthritis (AxSpA) | Non-radiographic Evidence-AxSpA

United States, Netherlands, Switzerland
ActivX Biosciences, Inc.
Kyorin Pharmaceutical Co.,Ltd

Completed

Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetics With Inadequate Glycemic Control on Metformin Alone (Synergy104)

Type 2 Diabetes

United States, Poland, Argentina, Russian Federation, Czech Republic, South Africa, Guatemala
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Withdrawn

Open-Label Study of TPI 287 for Patients With Metastatic Melanoma

Metastatic Melanoma

United States
Seattle Children's Hospital
Aadi Bioscience, Inc.

Completed

ABI-009 (Nab-rapamycin) for Surgically-Refractory Epilepsy (RaSuRE)

Epilepsy Intractable

United States
Spartan Bioscience Inc.
Mount Sinai Services

Completed

Spartan Cube CYP2C19 Method Comparison Study

Genotyping Techniques

Canada
Boston Children's Hospital
Entrinsic Bioscience Inc.

Terminated

Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome

Short Bowel Syndrome

United States
J3 Bioscience, Inc.
University of Utah

Completed

Preliminary Study of a Vaginal Lubrication Ring to Treat the Symptoms of Vaginal Dryness

Atrophic Vaginitis | Menopausal and Perimenopausal Disorder, Unspecified

United States
Virginia Commonwealth University
Meridian Bioscience, Inc.

Terminated

Prediction of Severity of Liver Disease by a 13C Octanoate Breath Test (OBT)

Metabolic Syndrome | Nonalcoholic Fatty Liver Disease

United States
University of Washington
Aadi Bioscience, Inc.

Active, not recruiting

Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas

Advanced Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma

United States
Meridian Bioscience, Inc.
Rabin Medical Center

Completed

13-C Urea Breath Test Using BreathID System and PPIs (Proton Pump Inhibitors)

Helicobacter Pylori Infection

Israel
J3 Bioscience, Inc.
Advanced Clinical Research

Completed

Efficacy of VR101 as a Personal Lubricant

Sexual Dysfunction, Physiological

United States
Sonoma State University
Entrinsic Bioscience Inc.

Completed

"Beverage Hydration Index" of Commercial Therapeutic Beverages

Healthy

United States
Virginia Commonwealth University
Meridian Bioscience, Inc.

Completed

Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis

Cirrhosis

United States, Israel
Hadassah Medical Organization
Meridian Bioscience, Inc.

Unknown

Prediction of Severity of Liver Disease Non Alcoholic Fatty Liver Disease in Patients With Suspected NAFLD by a 13C Octanoate Breath Test

NAFLD

Israel
University of Washington
Blaze Bioscience Inc.

Recruiting

A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

Stage III Lip and Oral Cavity Cancer AJCC v8 | Oral Cavity Squamous Cell Carcinoma | Stage I Lip and Oral Cavity Cancer AJCC v8 | Stage II Lip and Oral Cavity Cancer AJCC v8 | Stage IVA Lip and Oral Cavity Cancer AJCC v8

United States
Zaycor Healthcare Corp
BioScience Laboratories, Inc.

Not yet recruiting

Pilot Clinical Trial - Comparative Study of Two Material Concentration of OD-141309 (Odysseus-01)

Infectious Disease
Meridian Bioscience, Inc.
Bristol-Myers Squibb

Completed

Companion Protocol for ¹³C-Methacetin Breath Tests in BMS: NCT03486899, NCT03486912 Referenced Trials

NASH - Nonalcoholic Steatohepatitis

United States
Neurotrope Bioscience, Inc.
Worldwide Clinical Trials

Completed

A Study of Bryostatin in Moderately Severe to Severe Alzheimer's Disease Subjects Not On Memantine

Alzheimer Disease

United States
Massachusetts General Hospital
Aadi Bioscience, Inc.

Withdrawn

Safety and Efficacy of ABI-009 (Nab-rapamycin) in Combination With Pomalidomide and Dexamethasone for Relapsed and Refractory Multiple Myeloma

Multiple Myeloma

United States
Precera Bioscience, Inc.
University of Pittsburgh

Withdrawn

Comprehensive Medication Monitoring on Heart Failure Patient Outcomes

Heart Failure，Congestive

United States
Hadassah Medical Organization
Meridian Bioscience, Inc.

Unknown

¹³C-Methacetin Breath Test (MBT) Methodology Study

Cirrhosis | Healthy Subjects | Chronic Liver Disease

Israel
Rapamycin Holdings, Inc. dba Emtora Biosciences
LumaBridge

Active, not recruiting

Trial of eRapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance

Familial Adenomatous Polyposis

United States
Nobel Pharmaceuticals
Ainos, Inc. (f/k/a Amarillo Biosciences Inc.

Completed

Low Dose Interferon Alpha Treatment for Oral Ulcers of Behcet's Disease

Behcet Syndrome | Behcet Disease | Mucocutaneous Ulceration

Turkey
The University of Hong Kong
Imago BioSciences,Inc.

Recruiting

Bomedemstat (IMG-7289) Plus Ruxolitinib for Myelofibrosis

Myelofibrosis

Hong Kong
Ark Biosciences Inc.
Shanghai Ark Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic Scar

Hypertrophic Scar

China

Clinical Trials Sponsored by Leadiant Biosciences, Inc.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Colombia

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Rare Diseases

Drug Interventions

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