Clinical Trials Sponsored by Mack Eye Center

Total 668 results

Singapore National Eye Centre
National University Hospital, Singapore; Tan Tock Seng Hospital

Active, not recruiting

Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment

Polypoidal Choroidal Vasculopathy

Singapore
The Hearing Cooperative Research Centre
Royal Victoria Eye and Ear Hospital; Cochlear

Completed

Clinical Metrics for Assessing Cochlear Implant Recipient MAPs

Hearing Loss

Australia
The Hearing Cooperative Research Centre
Royal Victoria Eye and Ear Hospital; Cochlear

Completed

Tinnitus Suppression for Cochlear Implant Recipients

Tinnitus

Australia
The Hearing Cooperative Research Centre
Royal Victoria Eye and Ear Hospital; Cochlear

Completed

Cochlear Implant Low Power Strategy

Hearing Loss

Australia
Case Western Reserve University
National Eye Institute (NEI); Jaeb Center for Health Research

Completed

Cornea Preservation Time Study (CPTS)

Cornea Preservation Time | Endothelial Keratoplasty | Transplant Success | Endothelial Cell Density

United States
Singapore National Eye Centre
NeuroVision; Defence Medical Research Institute, Singapore Armed Forces

Completed

A Singapore Study to Assess How Neurovision Improve the Vision of Adults With Low to Moderate Myopia

Myopia

Singapore
Mark Dignan, PhD
National Cancer Institute (NCI); Virginia Commonwealth University

Completed

Promise Women Project

Cervical Cancer | Human Papilloma Virus

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; Regeneron Pharmaceuticals

Completed

Comparative Effectiveness Study of Intravitreal Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema (Protocol T)

Diabetic Macular Edema

United States
Manhattan Eye, Ear & Throat Hospital
Alcon Research; LuEsther T. Mertz Retinal Research Center

Completed

Treatment of Chronic Central Serous Chorioretinopathy With Open-Label Anecortave Acetate (CSC-AA)

Chronic Central Serous Chorioretinopathy

United States
Mark Eisenberg
Sunnybrook Health Sciences Centre; Unity Health Toronto; Queen Elizabeth II Health...

Completed

Evaluation of Varenicline (Champix) in Smoking Cessation for Patients Post-Acute Coronary Syndrome (EVITA) Trial (EVITA)

Acute Coronary Syndrome

Canada
Cochlear
The Hearing Cooperative Research Centre; Royal Victoria Eye and Ear Hospital

Completed

Intracochlear Potentials: Volta Study (CLTD5663)

Hearing Loss

Australia
Cochlear
The Hearing Cooperative Research Centre; Royal Victoria Eye and Ear Hospital

Completed

CHANGE Feasibility Study (CLTD5626)

Hearing Loss

Australia
Singapore National Eye Centre
Singapore Armed Forces; Defence Medical Environmental Research Institute

Completed

Efficacy of LASIK Versus PRK in Asians With Mild and Moderate Myopia

Myopia

Singapore
Anhui Medical University
Shanghai Eye Disease Prevention and Treatment Center; Beijing Center for Disease...

Recruiting

Community Intervention and Demonstration Area Construction

Refractive Errors | Myopia

China
Mark Pomerantz, MD
Merck Sharp & Dohme LLC; Rainier Therapeutics

Terminated

Ph 1B B-701 in Combination With Pembrolizumab in Metastatic Transitional Cell Carcinoma of the Urothelial Tract

Bladder Cancer

United States
Mark Dewhirst
National Cancer Institute (NCI); National Institutes of Health (NIH)

Withdrawn

To Evaluate the Characteristics of a Breast Cancer

Breast Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI); National Eye Institute (NEI)

Completed

S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000 (SEE)

Macular Degeneration | Cataract

United States
IDx LLC
The University of Texas Health Science Center, Houston; University of Pennsylvania and other collaborators

Completed

Computer Detection of Diabetic Retinopathy Compared to Clinical Examination (CDDR)

Diabetic Retinopathy

United States
University of California, San Francisco
National Eye Institute (NEI); Emory University; The Carter Center; Amhara Public...

Recruiting

Sanitation, Water, and Instruction in Face-washing for Trachoma I/II (SWIFT I/II)

Trachoma

Ethiopia
Gustav Stalhammar
The Swedish Society of Medicine; Swedish Cancer Society; Karolinska Trial Alliance and other collaborators

Recruiting

Adjuvant Melatonin for Uveal Melanoma (AMUM)

Uveal Melanoma | Uveal Melanoma, Posterior, Medium/Large Size | Eye Cancer, Intraocular Melanoma

Sweden
Steven R. Sanislo
Genentech, Inc.; California Pacific Medical Center; Pacific Eye Associates

Completed

Lucentis in Advanced Macular Degeneration

Macular Degeneration

United States
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH)

Completed

Effects of Pneumatic Vitreolysis on Vitreomacular Traction (AG)

Vitreomacular Traction

United States
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH)

Completed

Effects of Pneumatic Vitreolysis on Macular Hole (Protocol AH)

Vitreomacular Traction (VMT) | Full-thickness Macular Holes (MH)

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University
The Second People's Hospital of Foshan; Tianjin Medical University Eye Center

Recruiting

Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia Control

Eye Diseases | Refractive Errors | Myopia, Progressive

China
Canadian Cancer Trials Group
Cancer Research Institute, New York City; Personal Genome Diagnostics (PGDx); Mark Foundation for Cancer Research

Recruiting

Study of CTDNA Response Adaptive Immuno-Chemotherapy in NSCLC

Non-Small Cell Lung Cancer

Canada, United States
Mark A Hull, PhD FRCP
Yorkshire Cancer Research; Amarin Pharma Inc.

Active, not recruiting

EPA for Metastasis Trial 2 (EMT2)

Colon Cancer | Liver Metastasis

United Kingdom
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa

Retinitis Pigmentosa

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Gevokizumab for Active Scleritis

Scleritis

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Terminated

A Randomized, Controlled, Double-Masked, Clinical Trial of Autologous Serum Eye Drops for Severe Ocular Chronic Graft-versus-Host Disease (GVHD) in Hematopoietic Stem Cell Transplant (HSCT) Patients (GVHD ASED)

Graft vs Host Disease

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Diabetic Macular Edema

Diabetic Macular Edema

United States
Contamac Ltd
Andre Vision and Device Research; The Contact Lens Center at Optique; Premiere... and other collaborators

Completed

Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging

Contact Lens Complication | Debris in Post Lens Tear Reservoir

United States
Umeå University
Karolinska Institutet; Lund University; Göteborg University; Linkoeping University and other collaborators

Recruiting

The Glaucoma Nicotinamide Trial (TGNT)

Glaucoma

Sweden
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Topical Interferon Gamma-1b for Central Serous Chorioretinopathy

Macular Disease | Retinal Disease

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Ranibizumab and Bevacizumab for Diabetic Macular Edema

Diabetic Macular Edema

United States, United Kingdom
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Dextromethorphan for Diabetic Macular Edema (MiDME2)

Diabetic Macular Edema

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Terminated

Finasteride for Chronic Central Serous Chorioretinopathy

Retinal Disease

United States
The Hong Kong Polytechnic University
HOYA Lamphun Ltd; Centre for Eye and Vision Research

Recruiting

Baseline Relative Peripheral Refraction in Myopia Control

Myopia

Hong Kong
Centre for Eye and Vision Research
The Hong Kong Polytechnic University; University of Waterloo

Recruiting

Direct Discrimination of Quantum States by the Human Eye

Age-Related Macular Degeneration

Hong Kong
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious Uveitis

Uveitis

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis

Immunosuppression | Anterior Uveitis | Arthritis, Juvenile Idiopathic | Iritis

United States
Centre for Eye and Vision Research
The Hong Kong Polytechnic University; University of Waterloo

Recruiting

Optical Correction and Visual Functions of Adults With Amblyopia (SPECTRA)

Amblyopia

Canada, Hong Kong
Mark Hallett
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Transcranial Magnetic Stimulation to Treat Parkinson's Disease

Parkinson Disease

United States
Massachusetts Eye and Ear Infirmary
United States Naval Medical Center, San Diego; Brooke Army Medical Center; United... and other collaborators

Completed

Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy

Tonsillectomy | Adenoidectomy

United States
Pack Health
M.D. Anderson Cancer Center; The University of Texas Health Science Center,... and other collaborators

Recruiting

Comprehensive Outcomes for After Cancer Health (COACH)

Breast Cancer | Gastric Cancer | Ovarian Cancer | Lung Cancer | Survivorship

United States
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH); Regeneron...

Completed

Treatment for CI-DME in Eyes With Very Good VA Study (Protocol V)

Diabetic Macular Edema

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH); Regeneron...

Completed

Anti-VEGF vs. Prompt Vitrectomy for VH From PDR (AB)

Proliferative Diabetic Retinopathy | Vitreous Hemorrhage

United States, Canada
Columbia University
National Eye Institute (NEI); Centre Hospitalier National d'Ophtalmologie des... and other collaborators

Recruiting

Study of BEST1 Vitelliform Macular Dystrophy

Retinitis Pigmentosa | Best Vitelliform Macular Dystrophy

United States, Germany, France
Ji Hye Yoon
COSMAX; Global medical research center

Completed

Evaluation of Human Efficacy for Skin Moisturization and Wrinkle Improvement

Dry Skin

Korea, Republic of
The Hearing Cooperative Research Centre
Royal Victoria Eye and Ear Hospital; Cochlear; University of Melbourne

Terminated

Optimisation of Hybrid Fittings for Cochlear Implant Recipients

Hearing Loss

Australia
Mack Mitchell
National Institute on Alcohol Abuse and Alcoholism (NIAAA); The Cleveland Clinic and other collaborators

Completed

Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis

Acute Alcoholic Hepatitis

United States

Clinical Trials Sponsored by Mack Eye Center

Sponsors and Collaborators

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