Clinical Trials Sponsored by Wellcome Trust

Total 6270 results

Portsmouth Hospitals NHS Trust

Completed

Colonoscopy Outcome Database (COD)

Colonoscopy Procedures

United Kingdom
Portsmouth Hospitals NHS Trust

Completed

The Effects of Changing Light Levels on Contrast Sensitivity in Patients With Glaucoma (ENLIGHTEN)

Glaucoma

United Kingdom
Portsmouth Hospitals NHS Trust

Completed

Investigation of Inflammacheck to Measure Exhaled Breath Condensate Hydrogen Peroxide in Respiratory Conditions (VICTORY)

Respiratory Disease

United Kingdom
Rett Syndrome Research Trust

Completed

ASSESSING EMERALD AND MC10 BIOSTAMP nPOINT BIOSENSORS FOR RETT SYNDROME

Rett Syndrome

United States
Vestre Viken Hospital Trust

Active, not recruiting

Functional Results With Attune Fixed Bearing Posterior Stabilized Knee Arthroplasty (A-16)

Knee Arthroplasty

Norway
Nottinghamshire Healthcare NHS Trust

Completed

QbTest Utility for Optimising Treatment in ADHD (QUOTA) (QUOTA)

ADHD

United Kingdom
Portsmouth Hospitals NHS Trust

Completed

EXhaled Hydrogen Peroxide As a Marker of Lung Disease Study - Conformité Européenne (European Conformity) (EXHALE CE)

Point of Care Monitoring

United Kingdom
Portsmouth Hospitals NHS Trust

Completed

The IUSS Crohn's Study: A Feasibility Study

Inflammatory Bowel Diseases | Crohn Disease

United Kingdom
Portsmouth Hospitals NHS Trust

Completed

The Staff Stop Smoking Project (STOP)

Smoking Cessation

United Kingdom
North Bristol NHS Trust

Completed

GDNF in ideopathicParkinsons Disease

Idiopathic Parkinson Disease
North Bristol NHS Trust

Terminated

Accelerated vs Non-Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction: A Pilot Study (AVON ACL)

Anterior Cruciate Ligament Reconstruction

United Kingdom
Bedford Hospital NHS Trust

Unknown

Aqueous Release to Treat IOP Spikes Post-cataract Surgery

Post-Op Complication | Raised Ocular Pressure
Portsmouth Hospitals NHS Trust

Completed

Purastat® vs Standard Therapy for Haemostasis During Endoscopic Submucosal Dissection

Gastrointestinal Haemorrhage

United Kingdom
Vestre Viken Hospital Trust

Completed

Quadratus Lumborum Block for Abdominoplasty

Pain, Postoperative | Abdominoplasty

Norway
St Stephens Aids Trust

Unknown

SSAT 054: Non Genetic Factors in the Pathogenesis of IBD in Twins

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease

United Kingdom
Medway NHS Foundation Trust

Withdrawn

A Follow-net Investigation of a Randomised Study of Cystoscopy and Urethral Dilatation Versus Cystoscopy Alone in Women With Overactive Bladder Syndrome and Impaired Voiding

Overactive Bladder | Urinary Incontinence | Voiding Dysfunction
Bedford Hospital NHS Trust

Unknown

Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. (OCT)

Epiphora | Dry Eye Syndrome | Sjögren's Syndrome
Portsmouth Hospitals NHS Trust

Completed

Endo-cuff Assisted Vs. Standard Colonoscopy for Polyp Detection in Bowel Cancer Screening (E-CAP)

Colonic Polyps | Colonic Neoplasms

United Kingdom
Royal Cornwall Hospitals Trust

Unknown

Exercise as an Intervention in Endometrial Cancer Survivors

Quality of Life | Endometrial Cancer

United Kingdom
Walsall Healthcare NHS Trust

Unknown

RCT Novasure Versus Novasure + Mirena IUS in the Treatment of Menorrhagia

Menorrhagia

United Kingdom
Buckinghamshire Healthcare NHS Trust

Unknown

Exoskeletons for Spinal Cord Injury: A Feasibility Study

Spinal Cord Injury

United Kingdom
Buckinghamshire Healthcare NHS Trust

Unknown

Eyegaze Systems for Spinal Cord Injury: A Feasibility Study

Spinal Cord Injury

United Kingdom
Portsmouth Hospitals NHS Trust

Completed

High Definition Endoscopy With i-Scan for Small Colonic Polyp Evaluation: The HiScope Study (HiSCOPE)

Colonic Polyps
St Stephens Aids Trust

Unknown

Evolution of Cellular and Viral Resistance in HIV-infected Patients With Lymphoma (SSAT042)

Lymphoma | HIV

United Kingdom
St Stephens Aids Trust

Completed

Atazanavir/Ritonavir and Zinc Pharmacokinetic Study (SSAT043)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

PK of Tenofovir, Emtricitabine and Efavirenz in Healthy Volunteers

HIV Infections | HIV Infection

United Kingdom
St Stephens Aids Trust

Terminated

NNRTI/PI Toxicity Switch to Darunavir Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

Atazanavir/Ritonavir and Darunavir/Ritonavir PK Tail Study

HIV Infections | HIV

United Kingdom
St Stephens Aids Trust

Completed

Double Protease Inhibitor to Darunavir Switch Study

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Maraviroc 300 mg Twice Daily in HIV Negative Male Volunteers

HIV Infections

United Kingdom
St Stephens Aids Trust

Terminated

Pre-Exposure Prophylaxis Using TMC278LA

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Pharmacokinetics (PK) Study of Once Daily Darunavir/Ritonavir and Twice and Once Daily Raltegravir in HIV-infected Subjects

HIV Infections

United Kingdom
Malamed
Blackie Foundation Trust

Completed

The Use of Homeopathic-Based Treatment Approaches to Reduce the Prevalence of Malaria in Depressed Communities

Malaria

Sierra Leone
St Stephens Aids Trust

Completed

TMC 125 Blood Levels Study

HIV Infections

United Kingdom
African Malaria Network Trust

Unknown

Immunogenicity, Efficacy and Safety Study of an MSP3-LSP (Long Synthetic Peptide) Malaria Vaccine

Malaria

Mali
Hammersmith Hospitals NHS Trust

Unknown

Erythropoietin in Acute Myocardial Infarction

Acute Myocardial Infarction

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Imperial College Healthcare NHS Trust

Not yet recruiting

The PICM Risk Prediction Study - Application of AI to Pacing

Heart Failure | Pacemaker-Induced Cardiomyopathy | Pacemaker Complication

United Kingdom
Imperial College Healthcare NHS Trust
Chelsea and Westminster NHS Foundation Trust; Royal Brompton & Harefield NHS...

Completed

Testosterone Patch's Effects on the Cardiovascular System and Libido

Hypoactive Sexual Desire Disorder

United Kingdom
London School of Hygiene and Tropical Medicine
University College, London; Wellcome Trust; National Institute for Health Research... and other collaborators

Not yet recruiting

SUNRISE CRT: Radio Intervention to Stimulate Early Child Development (SUNRISE)

Child Development

Burkina Faso
Imperial College London
London School of Hygiene and Tropical Medicine; Wellcome Trust; Medical Research... and other collaborators

Completed

Early Childhood Malaria Prevention With Maloprim in The Gambia

Malaria

Gambia
London School of Hygiene and Tropical Medicine
University College, London; UNITAID; Liverpool School of Tropical Medicine; Population... and other collaborators

Completed

A Cluster Randomised Trial of Community-led Distribution of HIV Self-tests in Rural Malawi (HIV Self-Testing Africa [STAR])

HIV/AIDS

Malawi
University of Oxford
London School of Hygiene and Tropical Medicine; University College, London; KEMRI-Wellcome... and other collaborators

Unknown

First Line Antimicrobials in Children With Complicated Severe Acute Malnutrition (FLACSAM)

Antibiotic Resistance | Malnutrition Severe | Antibiotic Toxicity

Kenya, Uganda
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; Liverpool University Hospitals NHS... and other collaborators

Recruiting

Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction. (REMEDY-PILOT)

Coronary Disease | Angina Pectoris | Refractory Angina | Microvascular Angina | Microvascular Coronary Artery Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Haemodynamics of Mitral Regurgitation Reduction (STRESS-MR)

Mitral Regurgitation
Royal Brompton & Harefield NHS Foundation Trust
Chelsea and Westminster NHS Foundation Trust; Imperial College Healthcare NHS...

Unknown

Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy (OPTIMISE)

Venous Thrombosis | Insulin Resistance

United Kingdom
Papworth Hospital NHS Foundation Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; University... and other collaborators

Completed

Home Monitoring to Predict Exacerbation in Cystic Fibrosis (SmartCare)

Cystic Fibrosis

United Kingdom
University Hospital Southampton NHS Foundation...
Sheffield Teaching Hospitals NHS Foundation Trust; University Hospitals, Leicester and other collaborators

Completed

CPET and Outcome After Oesophagogastric Cancer Surgery

Upper Gastrointestinal Disorders

United Kingdom
University of Manchester
King's College Hospital NHS Trust; Cardiff University; University College London... and other collaborators

Not yet recruiting

Immune Profiles in Myasthenia Gravis

Myasthenia Gravis
Epsom and St Helier University Hospitals NHS Trust
King's College Hospital NHS Trust; Medway NHS Foundation Trust

Unknown

Metformin in Intrahepatic Cholestasis of Pregnancy (METRIC)

Pregnancy Complications | Intrahepatic Cholestases
Royal Brompton & Harefield NHS Foundation Trust
Oxford University Hospitals NHS Trust; Sherwood Forest Hospitals NHS Foundation...

Unknown

Ballooned Intercostal Drain Trial

Pneumothorax | Pleural Effusion

United Kingdom

Clinical Trials Sponsored by Wellcome Trust

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bahamas

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations