Search clinical trials for: Multicenter Randomized Study

Total 127019 results

Sun Yat-sen University

Recruiting

Localized Treatment Versus Palliative Chemotherapy in CRC Patients With 10 or More CRLM

Colorectal Neoplasms Malignant

China
Beijing Friendship Hospital

Recruiting

Comparison of Short-term Application of Dialysis Catheter With Tunnel-cuffed Catheter Versus Non-ccuffed Catheter: a Multicenter Prospective Cohort Study

Clarify the Difference of Short-term Infection Rate Between Diffrent Catheter

China
Kyowa Kirin Korea Co., Ltd.

Recruiting

Multicenter, Open, Prospective, 48 Weeks, Observational Study ,Evaluate the Safety and Efficacy of Nephoxil Capsule

Hyperphosphatemia

Korea, Republic of
Jian Chen

Recruiting

Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Hospital Universitario Central de Asturias

Recruiting

Prospective, Single-Arm, Multicenter Study to Evaluate the Effectiveness and Safety of Endovascular Treatment in Patients With Cerebral Aneurysms Using P64 and P48 Flow-Diverter Stents (pSPAIN_HPC)

Cerebral Aneurysm | Thromboembolic Disease

Spain
Institute of Hematology & Blood Diseases Hospital...
Henan Cancer Hospital; Tianjin Medical University Second Hospital; The Second... and other collaborators

Recruiting

A Randomized, Double-blind, Placebo-controlled, and Multi-center Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia

Immune Thrombocytopenia | Treatment

China
JHM BioPharma (Tonghua) Co. , Ltd.

Recruiting

A Phase I/II, Randomized, Double-blind, Placebo, and Active Controlled Clinical Study to Evaluate the Safety, Tolerability, Immunogenicity, and Preliminary Efficacy of JHM03 in Subjects With Moderate to Severe Glabellar Lines

Moderate to Severe Glabellar Lines

China
Hospital Clinic of Barcelona

Recruiting

Randomized Study of Physiological vs Right Ventricular Pacing in Patients With Normal Ventricular Function Post TAVI (PHYSTAVIII)

AV Block | Transcatheter Aortic Valve Implantation | Physiological Pacing | Right Ventricular Pacing | Preserved Left Ventricular Systolic Function

Spain
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Randomized Pilot Study Evaluating Isopropyl Alcohol and UVC Rays in Disinfection of Cell Phones (SaniPhone)

Cross Infection

Italy
Nantes University Hospital
Société Française d'Anesthésie et de Réanimation

Recruiting

Rapid Sequence Intubation and Hemodynamic Disorders in the Operating Room: a Prospective Multicenter Observational Study (CoC)

Rapid Sequence Intubation

France
Universidad de Colima

Not yet recruiting

Efficacy of Acceptance and Commitment Therapy on Serum GDF-15 Levels in Older Adults With and Without Depression: a Non-randomized Intervention Study (ACT GDF-15)

Depressive Disorder
The First Affiliated Hospital of Zhengzhou University
Techpool Bio-Pharma Co., Ltd.

Recruiting

Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study

Acute Ischemic Stroke

China
LimmaTech Biologics AG
GlaxoSmithKline

Recruiting

Assessing the Safety, Immune Response, and Early Efficacy of a Candida Vaccine in Women With Recurrent Vulvovaginal Candidiasis: A Randomized Controlled Study

Recurrent Vulvovaginal Candidiasis

Belgium
Proviva Therapeutics, Inc.

Not yet recruiting

A First-in-human (FIH), Multicenter, Open-Label, Phase I Study of PTX-912 in Patients With Locally Advanced/Metastatic Solid Tumors

Solid Tumor | Metastatic Cancer | Advanced Cancer
Changchun GeneScience Pharmaceutical Co., Ltd.
West China Hospital

Not yet recruiting

A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease

Systemic Sclerosis Associated Interstitial Lung Disease | Rheumatoid Arthritis Associated Interstitial Lung Disease (RA-ILD) | Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)

China
National Research Center for Hematology, Russia

Recruiting

Multicenter Study of Safety and Efficacy Nivolumab at the Fixed Dose 40 mg (Nivo40) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed PMBL

Primary Mediastinal Lymphoma

Russian Federation
NeuroSense Therapeutics Ltd.

Recruiting

A Phase 2, Randomized, Prospective Double-Blind, Single-Center, Placebo-controlled Study to Evaluate Safety, Tolerability, Target Engagement, and Efficacy of PrimeC in Patients With Mild to Moderate Alzheimer's Disease. (RoAD)

Alzheimer Disease

Israel
AstraZeneca

Recruiting

A National, Multicenter, Prospective, Observational Study to Assess Patient Characteristics, Treatment Algorithms and Disease Management of Hyperkalaemia Patients With Chronic Kidney Disease or Under Dialysis or With Heart Failure, Treated With Sodium Zirconium Cyclosilicate in Greece (SHIELD)

Hyperkalaemia

Greece
RenJi Hospital

Not yet recruiting

Prospective, Multicenter Clinical Study of Prolonged-release Tacrolimus in Stable Pediatric Liver Transplant Recipients

Liver Transplant

China
Beijing Tiantan Hospital

Not yet recruiting

Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis (SPECIALS)

Amyotrophic Lateral Sclerosis

China
Zai Lab (Shanghai) Co., Ltd.
Zai Lab (US) LLC

Recruiting

An Open-label, Multicenter Study of ZL-1310 in Subjects With Small Cell Lung Cancer

SCLC

United States, China
ACADIA Pharmaceuticals Inc.

Recruiting

Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States, Canada, United Kingdom
Faculty of Dental Medicine for Girls

Recruiting

Assessment of Low Level Laser Therapy Effect on Treatment Outcomes of Bony Supported Distal Jet for Correction of Angle Class II Malocclusion (Randomized Clinical Trial) (LLLT)

This Study Focus on the Effect of Low-Level Light Therapy on the Amount of Upper Molar Distalization

Egypt
M.D. Anderson Cancer Center

Recruiting

Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)

Oropharyngeal Neoplasms | Robotic Surgery and/or Radiotherapy | Lymphoscintigraphy

United States
Baskent University

Not yet recruiting

The Effect of Digital Technology-Supported Education on Patients Undergoing Breast Reconstruction After Mastectomy: A Randomized Controlled Study

Breast Cancer
Eslam Mohamed AHmed

Not yet recruiting

Femoral Neck Locking Plate Vs Multiple Cannulated Cancellous Screws in Treatment of Femoral Neck Fractures in Young Adults: Randomized Controlled Clinical Trial Study

Femoral Neck Fractures

Egypt
Haukeland University Hospital
Nordlandssykehuset HF; Helse Møre og Romsdal HF; Helse Fonna HF; Oslo universitetssykehus... and other collaborators

Not yet recruiting

The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism (NADAPT)

Multiple System Atrophy | Progressive Supranuclear Palsy | Corticobasal Syndrome

Norway
Zai Lab (Hong Kong), Ltd.

Recruiting

A Phase 3b Randomized, Double-blind, Multi-center Study to Compare the Safety and Efficacy of Omadacycline to Moxifloxacin for Treating Adult Subjects With CABP (public)

Community-acquired Bacterial Pneumonia

China
Apellis Pharmaceuticals, Inc.

Recruiting

A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Geographic Atrophy

United States
McMaster University
Canadian Chiropractic Research Foundation; Surgical Methods Centre, McMaster... and other collaborators

Not yet recruiting

The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study

Back Pain

Canada
KU Leuven
National Institute for Health and Disability Insurance (NIHDI), Belgium; Haute...

Recruiting

The Effectiveness of a Functional Capacity Evaluation Among Persons on Sick Leave or Work Disability (FCE)

Absenteeism | Return to Work | Sick Leave

Belgium
National Cancer Center, Korea

Recruiting

A Randomized Phase II Study of LAZE rtiNib Alone Versus Lazertinib Plus bevaCizumab for NSCLC With EGFR + & Smoker

Lazertinib

Korea, Republic of
Carl Backes, MD
Children's Hospital of Philadelphia; National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Cord Clamping Among Neonates With Congenital Heart Disease (CORD-CHD)

Congenital Heart Disease (CHD)

United States, Canada
Changhai Hospital
Wuxi Hisky Medical Technology Co Ltd

Not yet recruiting

Confocal Laser Microendoscopy (CellTouch) for the Diagnosis of Early Gastric Cancer: A Multicenter Clinical Study

Early Gastric Cancer

China
University Hospital, Angers

Not yet recruiting

Medical Honey for Wound Treatment in Intensive Care. (MICARéa) Randomized, Controlled, Single-center Pilot Study. (MICAREA)

Critical Illness | Wound Heal
Altesa Biosciences, Inc.
Virtus Respiratory Research

Recruiting

RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection

Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Lung Diseases | Pulmonary Disease, Chronic Obstructive | Enterovirus Infections | Copd | Pulmonary Disease | Respiratory Disease | Respiratory Complication | Upper Respiratory Tract Infections | Respiratory Viral Infection | ... and other conditions

United Kingdom
Maastricht University Medical Center
Gelre Hospitals

Recruiting

Healthcare Utilization in Liver Cirrhosis Patients, a Multicenter Retrospective Cohort Study

Liver Cirrhosis

Netherlands
National Institute of Allergy and Infectious Diseases...

Recruiting

Safety Study of SLV213 for the Treatment of COVID-19.

COVID-19

United States
Novartis Pharmaceuticals

Recruiting

A Proof of Concept and Dose-finding Study of XXB750 in Patients With Heart Failure

Heart Failure

Italy, Spain, United States, Japan, China, Germany, Taiwan, Bulgaria, Denmark, France, Portugal, Slovakia
Saglik Bilimleri Universitesi Gazi Yasargil Training...

Not yet recruiting

Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study (Effects of Dex)

Rhinoplasty Surgery
Cukurova University

Recruiting

Evaluation of the Effect of Reiki on Surgical Fear and Anxiety in Laparoscopic Cholecystectomy; Randomized Controlled Study

Supportive Care

Turkey
Pan Xiangbin

Recruiting

A Prospective, Multicenter, Single-arm Study to Evaluate a Transcatheter Aortic Valve System Safety and Efficacy for the Treatment of Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

China
The Affiliated Hospital of Hangzhou Normal University

Not yet recruiting

Study on MAFLD-related Cirrhosis Prevention and Treatment Strategies (SMART)

Cirrhosis | Metabolic Dysfunction-associated Fatty Liver Disease
University Hospital, Caen

Not yet recruiting

IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation

Hematologic Malignancy | BTKi-induced Atrial Fibrillation | Atrial Fibrillation Catheter Ablation

France
Liquidia Technologies, Inc.

Recruiting

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH (ASCENT)

Pulmonary Hypertension | Interstitial Lung Disease

United States
Zero Point Five Therapeutics

Not yet recruiting

Phase 3, Multi-center, Prospective, Randomized, Double-blind, Placebo- Controlled Study to Evaluate the Effectiveness and Safety of ZP5-9676 for the Treatment of Soil Transmitted Helminthiasis (STH)

Soil-Transmitted Helminthiasis (STH)

Brazil, Ghana
Nadir Hastalıkları Araştırma Derneği

Recruiting

A Multicenter Selective Screening Study to Investigate the Frequency of Neuronal Ceroid Lipofuxinosis Type 2 (CLN2) (ENIGMA)

Neuronal Ceroid Lipofuxinosis Type2 (CLN2)

Turkey
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Multicenter, Open-label Extension Study Evaluating the Efficacy and Safety of IBI311 in Subjects With Thyroid Eye Disease

Thyroid Eye Disease, TED

China
Zhejiang University

Recruiting

Prospective, Single-arm, Multicenter Clinical Study on Haploidentical Hematopoietic Stem Cell Transplantation in Patients With MRD Positive CD19+ALL Treated With Conditioning Regimens Containing Blinatumomab

Acute Lymphoblastic Leukemia

China
Fundació Sant Joan de Déu
Hospital Universitari Vall d'Hebron Research Institute; Fundació La Marató... and other collaborators

Recruiting

Study of an Early Parenting Intervention for Children With Genetic Abnormalities and Mental Health Problems (The GAP)

Parenting | Genetic Syndrome | Language Development | Autism or Autistic Traits

Spain

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