Search clinical trials for: Pharmacokinetics

Total 10351 results

Kanyos Bio, Inc., a wholly-owned subsidiary of...
Pfizer

Recruiting

A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it)

Celiac Disease

United States, Australia, New Zealand
Elina Brinck

Not yet recruiting

KetaMoHydBup: Pharmacokinetic Interaction of S-ketamine, Morphine, Hydromorphone and Buprenorphine (KetaMoHydBup)

The Effect of S-ketamine on Pharmacokinetics of Morphine, Hydromorphone, and Buprenorphine
Redx Pharma Plc
Simbec Research

Recruiting

Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of RXC007 in Idiopathic Pulmonary Fibrosis

Fibrosis | IPF

Italy, Spain, United States, Belgium, United Kingdom, Austria, Czechia, Poland, Switzerland
Bellus Health Inc. - a GSK company

Recruiting

Assessment of the Pharmacokinetics of BLU-5937 Extended Release Prototypes and a BLU-5937 Immediate Release Reference Formulation

Healthy | Cough

United Kingdom
Xiaobo Yang, MD

Recruiting

The Effects of ECMO on the Pharmacokinetics of Hydromorphone

Extracorporeal Membrane Oxygenation

China
Policlinico Hospital
Pfizer

Recruiting

Nosocomial Infections in Patients With ARDS Treated With ECMO (INF-ECMO)

Acute Respiratory Distress Syndrome | Extracorporeal Membrane Oxygenation Complication | Nosocomial Infection

Italy
Sinew Pharma Inc.

Recruiting

A Partial Randomized, Single-blind or Open-label, Dose-escalation With Multiple-dose Design Study to Evaluate the Pharmacokinetics of Acetaminophen and Its Toxic Metabolites With Panadol® and SafeTynadol® in Healthy Volunteers

Hepatitis | Pharmacology

Taiwan
Hoffmann-La Roche

Recruiting

A Study Of The Efficacy, Safety, And Pharmacokinetics Of The Port Delivery System With Ranibizumab In Chinese Patients With Neovascular Age-Related Macular Degeneration

Neovascular Age Related Macular Degeneration | nAMD

China
Hartford Hospital
Merck Sharp & Dohme LLC; University of Texas Southwestern Medical Center; University... and other collaborators

Recruiting

Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic Fibrosis

Pneumonia, Bacterial | Cystic Fibrosis

United States
Dr. Niina Kleiber

Recruiting

Oral vs IV Acetaminophen for Long-bone Fracture in Children

Pain

Canada
Amsterdam UMC, location VUmc

Not yet recruiting

Alternative Dosing Scheme of Pomalidomide 4 mg Every Other Day Versus Pomalidomide 2 mg and 4 mg Every Day; the POMAlternative Study (POMAlternative)

Multiple Myeloma | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory
Corcept Therapeutics

Recruiting

Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Miricorilant

Non-alcoholic Steatohepatitis (NASH)

United States
Neurocrine Biosciences

Recruiting

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-1117568 in Adults With Schizophrenia

Schizophrenia

United States
Beijing Friendship Hospital

Recruiting

Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLH

Hemophagocytic Lymphohistiocytosis

China
Kyungpook National University Chilgok Hospital

Recruiting

Pharmacokinetics of Oral Antiplatelet Agents After Distal Gastrectomy

Cardiovascular Diseases | Cerebrovascular Disease | Stomach Neoplasm

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Melphalan in People With Lymphoma Getting an Autologous Hematopoietic Cell Transplant

Lymphoma | Lymphoma, B-Cell | Lymphoma, Non-Hodgkin | Lymphoma, T-Cell | Lymphoma, Hodgkin

United States
CARE Pharma Shanghai Ltd.

Recruiting

A Study on the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of CAN106 in Subjects With PNH

Hemolysis | PNH

China
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single and Multiple Ascending Doses Study to Evaluate the Safety and Pharmacokinetics of RBD5044

Health Volunteer

Australia
Zhengzhou University
Fundamenta Therapeutics, Ltd.

Not yet recruiting

Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Refractory or Relapsed B Cell Lymphoma

Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited, r/r B-NHL
Radboud University Medical Center

Not yet recruiting

The Influence of Having Bariatric Surgery on the Pharmacokinetics, Safety and Efficacy of the Novel Non-nucleoside Reverse Transcriptase Inhibitor Doravirine (LABRADOR)

HIV Infections | Bariatric Surgery Candidate
Arcus Biosciences, Inc.

Recruiting

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors (ARC-20)

Clear Cell Renal Cell Carcinoma | Solid Tumors

Korea, Republic of, United States
medac GmbH
Synteract, Inc.

Recruiting

Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics

Myelodysplastic Syndrome (MDS) | Acute Myeloid Leukaemia (AML) | Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

United States
Godavari Biorefineries Limited

Not yet recruiting

Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers

COVID-19

India
Chinese University of Hong Kong
Prince of Wales Hospital, Shatin, Hong Kong

Recruiting

Pharmacokinetics of Apixaban in Peritoneal Dialysis

Atrial Fibrillation

Hong Kong
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥2 Years to <12 Years of Age With Uncontrolled Chronic Spontaneous Urticaria (CSU) (LIBERTY-CSU CUPIDKids)

Chronic Spontaneous Urticaria

United States, Canada, Japan
Assistance Publique - Hôpitaux de Paris

Recruiting

Baricitinib in the Treatment of New-onset Juvenile Dermatomyositis (MYOCIT) (MYOCIT)

Juvenile Dermatomyositis

France
AlaMab Therapeutics (Shanghai) Inc.

Recruiting

Study to Evaluate the Safety and Pharmacokinetics of ALMB-0166 in Patients With Acute Spinal Cord Injury

Acute Spinal Cord Injury

China
Kira Pharmacenticals (US), LLC.

Not yet recruiting

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat Glomerulonephritis

Glomerulonephritis
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Subcutaneous Injections of HRS9531 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

China
RemeGen Co., Ltd.

Recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Disitamab Vedotin Combined With RC98 in the Treatment of Subjects With HER2-expressing Locally Advanced or Metastatic Gastric Cancer (Including AEG)

Gastric Cancer

China
Ove Andersen
University of Copenhagen; Glostrup University Hospital, Copenhagen; University... and other collaborators

Recruiting

Sativex® and Gentamicin for Optimized Pharmagological Treatment in Older Patients (CanPan) (CanPan)

Anorexia | Malnutrition | Aging | Pharmacokinetics | Cannabis | Renal Function | Emergency Service, Hospital

Denmark
Hoffmann-La Roche
Chugai Pharmaceutical Co.

Recruiting

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Patients With Anti-N-Methyl-D-Aspartic Acid Receptor (NMDAR) Or Anti-Leucine-Rich Glioma-Inactivated 1 (LGI1) Encephalitis (Cielo)

NMDAR Autoimmune Encephalitis | LGI1 Autoimmune Encephalitis

United States, Korea, Republic of, China, Japan, Czechia, Italy, Poland, Austria, Brazil, Argentina, Netherlands, Taiwan, Denmark, France, Ghana
Shanghai Zhimeng Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CB03-154 in Healthy Participants

Healthy Volunteers

United States
The Affiliated Hospital of Qingdao University

Not yet recruiting

SPEL as Introductive Treatment Following Immune-chemotherapy as Consolidated Therapy for R/R DLBCL With p53 and/or c-Myc Expression

DLBCL

China
Spero Therapeutics

Recruiting

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)

United States
Celltrion

Recruiting

To Compare Pharmacokinetics, Efficacy, and Safety of CT-P17 With Humira in Patients With Moderate to Severe Chronic Plaque Psoriasis

Moderate to Severe Chronic Plaque Psoriasis

Estonia
University of Michigan

Recruiting

Ultrasonic Deep Brain Stimulation During Anesthetic Sedation

Mental Function

United States
University Hospital, Montpellier

Recruiting

Mepolizumab Pharmacokinetics Among Patients With Severe Asthma (CESAM)

Asthma

France
Foresee Pharmaceuticals Co., Ltd.
QPS Holdings LLC; Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

Efficacy, Safety, and Pharmacokinetics of Leuprolide Mesylate in Subjects With Central Precocious Puberty

Puberty; Precocious, Central

United States, China, Taiwan, Puerto Rico
University Hospital, Montpellier

Not yet recruiting

Pharmacokinetic Modeling of Methadone (PKMETHAHOME)

Toxicomania
University of Texas Southwestern Medical Center

Recruiting

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

Transthyretin Cardiac Amyloidosis

United States
Qilu Pharmaceutical Co., Ltd.

Recruiting

Safety, Tolerability and Pharmacokinetics Study of QLH11906 in Patients With Advanced Solid Tumors Harboring MAPK Pathway Alterations.

Advanced Solid Tumors Harboring MAPK Pathway Alterations

China
Genentech, Inc.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumors | Metastatic Solid Tumors

Canada, Korea, Republic of, United States, Brazil, Australia, Argentina, Spain, New Zealand, Poland
University of Chicago
Lucile Packard Children's Hospital

Not yet recruiting

Oxytocin Pharmacokinetics and Pharmacodynamics

Blood Loss | Cesarean Section Complications | Post Partum Hemorrhage

United States
Advenchen Laboratories Nanjing Ltd.

Recruiting

A Study of Diet Influence of AL8326 in Chinese Healthy Adult Subjects

Pharmacokinetics | Diet, High-Fat

China
Vir Biotechnology, Inc.

Recruiting

Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434

Cirrhosis | Hepatic Impairment

United States
Maisa N. Feghali, MD

Recruiting

Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes

Gestational Diabetes

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Efficacy of Cisplatin Micelle Injection (HA132) in Patients With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors

China
Shanghai Virogin Biotech Co., Ltd.

Recruiting

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2025 in Patients With Solid Tumors

Advanced Malignant Solid Tumor

China
Kira Pharmacenticals (US), LLC.

Not yet recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of KP104

Paroxysmal Nocturnal Hemoglobinuria

China

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