Clinical Trials Sponsored by CRISPR Therapeutics

Total 6373 results

Motus Therapeutics, Inc.
Michael J. Fox Foundation for Parkinson's Research

Terminated

A Phase 2 Study to Evaluate the Safety and Efficacy of RM-131 in Patients With Parkinson's Disease & Chronic Constipation (MOVE-PD)

Parkinson's Disease

United States
Ception Therapeutics
Cephalon

Completed

Efficacy and Safety Study of Reslizumab to Treat Poorly Controlled Asthma

Asthma

United States, Canada
The Center for Rheumatic Disease, Allergy, & Immunology
Grifols Therapeutics LLC

Completed

Efficacy of IgIv in Patients With IgG Subclass Deficiency and Recurrent Infections

Infections | IgG Deficiency

United States
Etan Orgel
Therapeutic Advances in Childhood Leukemia Consortium

Recruiting

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL (IDEAL2)

Obesity | B-cell Acute Lymphoblastic Leukemia

United States
Jagiellonian University
Specialist Diagnostic and Therapeutic Center MEDICINA

Completed

Trial on Innovative Technologies in Colonoscopy (RCT-IC)

Neoplasms | Polyps | Inflammatory Bowel Disease

Poland
Rong Tao
Novatim Immune Therapeutics (Zhejiang) Co., Ltd.

Recruiting

CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL

Acute Lymphoblastic Leukemia, in Relapse | B-cell Lymphoma Refractory | B-cell Lymphoma Recurrent | Acute Lymphoblastic Leukemia With Failed Remission

China
Ray Therapeutics, Inc.
The Vision Research and Assessment Institute (VRAI)

Recruiting

Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Retinitis Pigmentosa Patients

Retinitis Pigmentosa

United States
Megan Kruse, MD
AnHeart Therapeutics Inc.

Not yet recruiting

Taletrectinib in Previously Treated Metastatic CDH1-mutated Invasive Lobular Cancer (ILC)

Breast Cancer | Metastatic Breast Cancer

United States
Institute of Hematology & Blood Diseases Hospital...
Suzhou Fundamenta Therapeutics

Recruiting

CAR-T for Autoimmune Hemolytic Anemia Patients Who Have Failed Three or More Lines of Therapy

Autoimmune Hemolytic Anemia | CD19 CAR-T Cell Infusion

China
Second Affiliated Hospital, School of Medicine,...
Westlake Therapeutics

Recruiting

WTX212A Monotherapy and in Combination With PD -1/PD-L1 Monoclonal Antibody

Advanced Lung Cancer

China
China Medical University, China
Shanghai First Song Therapeutics Co., Ltd

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of Anti-HER2-CAR-T Cells Injection in Patients With Solid Tumors

Solid Tumor

China
Jerry Vockley, MD, PhD
Acer Therapeutics Inc.

Recruiting

Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)

Medium-chain Acyl-CoA Dehydrogenase Deficiency

United States
Uppsala University
Karolinska University Hospital; Uppsala University Hospital; Elicera Therapeutics

Recruiting

CAR20(NAP)-T Therapy for B Cell Lymphoma (CARMA-01 Study) (CARMA-01)

B-cell Lymphoma

Sweden
Mayur Narkhede
ADC Therapeutics S.A.

Recruiting

Addition of Loncastuximab Tesirine to Acalbrutinib , Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
Shanghai Jun Pai Ying Shi Therapeutics Co., Ltd.
Sponsor GmbH

Recruiting

A Clinical Study of IMP4297 Capsule (JS109) Combined With Irinotecan in the Treatment of Advanced Malignant Solid Tumors

Advanced Solid Tumors

China
Foundation for Angelman Syndrome Therapeutics,...
Queensland University of Technology

Recruiting

The Global Angelman Syndrome Registry (GASR)

Angelman Syndrome

Australia
Shayna Sarosiek, MD
ADC Therapeutics S.A.

Recruiting

Loncastuximab Tesirine in WM

Waldenstrom Macroglobulinemia

United States
Sunshine Lake Pharma Co., Ltd.
Nicoya Therapeutics (Shanghai) Co., Ltd.

Not yet recruiting

HEC53856 Phase Ib Study in Patients With Non-dialysis Renal Anemia

Chronic Kidney Diseases | Renal Anemia

China
Sunshine Lake Pharma Co., Ltd.
Nicoya Therapeutics (Shanghai) Co., Ltd.

Not yet recruiting

Study of HEC53856 in Patients With Subjects With End-Stage Renal Disease Receiving Dialysis.

Hemodialysis | Peritoneal Dialysis

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors

Advanced Malignant Solid Tumor

China
Shanxi Province Cancer Hospital
Novatim Immune Therapeutics (Zhejiang) Co., Ltd.

Recruiting

Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell Lymphoma

Lymphoma, B-Cell

China
Serhat Gumrukcu, MD PhD
Frida Therapeutics LLC

Recruiting

Clinical Specimen Collection From Pompe Disease Patients

Pompe Disease

United States
Dana-Farber Cancer Institute
Eli Lilly and Company; Effector Therapeutics

Recruiting

RESOLVE: Abemaciclib + Letrozole +/- Metformin or Zotatifin in Endometrial or Low-Grade Serous Ovarian Cancer

Ovarian Cancer | Endometrial Cancer

United States
Spark Therapeutics, Inc.
Children's Hospital of Philadelphia; University of Iowa

Active, not recruiting

Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis

Leber Congenital Amaurosis | Inherited Retinal Dystrophy Due to RPE65 Mutations

United States
Jeffrey Clarke
Merck Sharp & Dohme LLC; Grid Therapeutics

Suspended

Study of GT103 in Combination With Pembrolizumab in Refractory, Metastatic Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer | Metastatic NSCLC | Recurrent Non Small Cell Lung Cancer

United States
SWOG Cancer Research Network
National Cancer Institute (NCI); Halozyme Therapeutics

Completed

S1313, PEGPH20 in Treating Patients With Newly Diagnosed Metastatic Pancreatic Cancer

Metastatic Pancreatic Adenocarcinoma

United States
University of Alabama at Birmingham
Lung Biotechnology PBC; United Therapeutics

Withdrawn

Porcine Kidney Xenotransplantation in Patients With End-Stage Kidney Disease

Kidney Failure, Chronic

United States
Anwaar Saeed
Actuate Therapeutics Inc.; Incyte Corporation

Active, not recruiting

9-ING-41 Plus Retifanlimab and Gemcitabine/Nab-Paclitaxel in Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)

Pancreatic Adenocarcinoma

United States
Insight Therapeutics, LLC
Brown University; Case Western Reserve University; Seqirus

Completed

Adjuvanted Influenza Vaccination in U.S. Nursing Homes

Influenza | Influenza-like Illness

United States
Intensity Therapeutics, Inc.
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 (IT-01)

Sarcoma | Lymphoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Bile Duct Cancer | Colon Cancer | Liver Cancer | Squamous Cell Carcinoma | Chordoma of Sacrum

United States, Canada
Vidac Pharma
PharPoint Research, Inc.; Therapeutics, Inc.; Medistat Ltd., Israel

Completed

Study to Evaluate the Efficacy, Safety, and Tolerability of Topical VDA-1102 Ointment in Subjects With Actinic Keratosis (Phase2b)

Actinic Keratosis

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury

Acute Lung Injury | ARDS | COVID-19 Pneumonia

United States
H. Lee Moffitt Cancer Center and Research Institute
Aprea Therapeutics

Completed

Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm

United States
Craig McDonald, MD
Cardero Therapeutics, Inc.

Completed

Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)

Becker Muscular Dystrophy

United States
Craig McDonald, MD
Cardero Therapeutics, Inc.

Completed

Plus Epicatechin Duchenne Muscular Dystrophy in Non-ambulatory Adolescents

Duchenne Muscular Dystrophy

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

PART A: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and With mGluR Mutations

Attention Deficit Hyperactivity Disorder

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

Pharmacokinetic and Tolerability Study of NFC-1 in Subjects Aged 6-17 Years With ADHD

Attention Deficit Disorder With Hyperactivity

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

A Noninterventional Genotype/Phenotype Study of mGluR Mutations in Children and Adolescents With ADHD

Attention Deficit Disorder With Hyperactivity

United States
Instituto Grifols, S.A.
Hospital Clinic of Barcelona

Completed

Effects of Long Term Albumin 20% Administration in Patients With Cirrhosis and Ascites.

Cirrhosis | Ascites

Spain
Cerenis Therapeutics, SA
South Australian Health and Medical Research Institute

Completed

CER-001 Atherosclerosis Regression ACS Trial (CARAT)

Acute Coronary Syndromes

United States, Australia, Netherlands, Hungary
Factor Therapeutics Ltd.
Parexel; ARANZ Medical; Almac Clinical Services LLC

Unknown

Study of VF001-DP in Patients With Chronic Venous Leg Ulcers

Pathologic Processes | Cardiovascular Diseases | Vascular Diseases | Skin Diseases | Ulcer | Leg Ulcer | Skin Ulcer | Varicose Ulcer

United States
Gonzalez-Heydrich, Joseph, M.D.
Boston Children's Hospital; Seaside Therapeutics, Inc.

Terminated

TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers

Autism

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); PTC Therapeutics

Completed

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
New York Hospital Queens
NYHQ Cardiac Health Center; Pivotal Therapeutics

Unknown

An Open-Label Study of Vascazen in Cardiac Rehab Patients With Deficient Blood Omega-3 Fatty Acid Levels (CARE)

Dyslipidemia

United States
Kona Research Center
Integrative Therapeutics, Inc.; Bioenergy Life Science, Inc.

Completed

Treatment of Chronic Fatigue Syndrome and Fibromyalgia With D-ribose- a Multicenter Study

Fibromyalgia | Chronic Fatigue Syndrome

United States
University of Calgary
University of Toronto; Precisio Biotix Therapeutics, Inc.

Not yet recruiting

Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection (PHAGE-2024-01)

Staphylococcus Aureus Infection | Prosthetic Joint Infections of Hip
Juno Therapeutics, Inc., a Bristol-Myers Squibb...
Celgene Corporation

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Liso-cel Compared to Standard of Care in Adults With Relapsed or Refractory Follicular Lymphoma

Relapsed or Refractory Follicular Lymphoma
Juno Therapeutics, Inc., a Bristol-Myers Squibb...
Celgene Corporation

Recruiting

A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis or Progressive Forms of Multiple Sclerosis

Multiple Sclerosis

United States, Spain, Germany, Belgium, France, United Kingdom, Italy
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms

Digestive System Neoplasms

China
Steven Hays, MD
OrphAI Therapeutics

Recruiting

LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome. (INSPO-BOS)

Lung Transplantation | Chronic Lung Allograft Dysfunction | Bronchiolitis Obliterans Syndrome

United States

Clinical Trials Sponsored by CRISPR Therapeutics

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kyrgyzstan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations