Search clinical trials for: Irinotecan onkovis

Total 1536 results

Yale University

Terminated

Neoadjuvant Modified FOLFIRINOX and Stereotactic Body Radiation Therapy in Borderline Resectable Pancreatic Adenocarcinoma

Pancreatic Cancer

United States
National Cancer Institute (NCI)
United Therapeutics

Completed

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

Recurrent Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

Pancreatic Adenocarcinoma | Resectable Pancreatic Carcinoma

United States
ERYtech Pharma

Completed

Study of Eryaspase in Combination With Chemotherapy Versus Chemotherapy Alone as 2nd-Line Treatment in PAC (Trybeca-1)

Pancreatic Adenocarcinoma

United States, United Kingdom, France
Innovent Biologics (Suzhou) Co. Ltd.

Completed

First in Human Study of IBI308 in Chinese Subjects With Advanced Solid Tumors

Cancer, Solid Tumor

China
Ipsen

Completed

Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma

Pancreatic Cancer

United States, Spain, Australia
AIO-Studien-gGmbH
Servier Deutschland GmbH; Crolll Gmbh

Active, not recruiting

2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapy (PREDICT)

Metastatic Pancreatic Cancer | Locally Advanced Pancreatic Cancer

Germany
Agenus Inc.
European Network of Gynaecological Oncological Trial Groups (ENGOT)

Withdrawn

Balstilimab Versus Investigator Choice Chemotherapy in Patients With Recurrent Cervical Cancer (BRAVA)

Advanced Cancer | Metastatic Cervical Cancer

United States, Armenia
Washington University School of Medicine
Ipsen

Completed

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
Massachusetts General Hospital
National Cancer Institute (NCI)

Active, not recruiting

A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers

GastroEsophageal Cancer

United States
EpicentRx, Inc.

Completed

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

Carcinoma, Non-Small-Cell Lung | Ovarian Epithelial Cancer | Neuroendocrine Tumors | Small Cell Carcinoma

United States
Jonsson Comprehensive Cancer Center
Medivation, Inc.; BioMarin Pharmaceutical; Translational Research in Oncology

Completed

PARP Inhibitor BMN-673 and Temozolomide or Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Metastatic Cancer | Unspecified Adult Solid Tumor

United States
AstraZeneca
Syneos Health

Completed

Study to Assess the Safety and Preliminary Efficacy of AZD0156 at Increasing Doses Alone or in Combination With Other Anti-cancer Treatment in Patients With Advanced Cancer (AToM)

Advanced Solid Tumours

United States, Spain, Korea, Republic of, United Kingdom
Italian Sarcoma Group

Completed

Protocol for the Treatment of Metastatic Ewing Sarcoma (EW-2)

Ewing's Sarcoma (ES)

Italy
Ludwig-Maximilians - University of Munich

Active, not recruiting

First-line Therapy in Metastatic PDAC (FOOTPATH)

Metastatic Pancreatic Cancer

Germany
Federation Francophone de Cancerologie Digestive

Withdrawn

Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery

Colorectal Cancer | Metastatic Cancer

France
Changhoon Yoo
Ulsan University Hospital; Inje University; Kyungpook National University Chilgok... and other collaborators

Completed

Nal-IRI(Nanoliposomal Irinotecan) Plus 5-FU/LV in Metastatic Biliary Tract Cancer

Metastatic Biliary Tract Cancer

Korea, Republic of
Federation Francophone de Cancerologie Digestive

Active, not recruiting

Study of the Practice of Debiri in France

Colorectal Adenocarcinoma | Hepatic Metastases

France
Institut Cancerologie de l'Ouest

Completed

Efficacy and Tolerance Evaluation in FOLFIRINOX Dose Adjusted in Elderly Patients With a Metastatic Pancreatic Cancer (PAMELA70)

Toxicity | Pancreatic Metastatic Cancer

France
Cardiovascular and Interventional Radiological...

Completed

CIRSE Registry for LifePearl Microspheres (CIREL)

Neoplasm Metastasis | Colorectal Carcinoma

Austria
Eisai Inc.

Completed

Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Children With Refractory or Recurrent Solid Tumors

Ewing Sarcoma | Rhabdomyosarcoma | Refractory or Recurrent Solid Tumors | Non-Rhabdomyosarcoma Soft Tissue Sarcoma

Spain, United Kingdom, Italy, France, Germany, Greece, Poland, Switzerland
Samsung Medical Center

Withdrawn

FOLFIRI as Salvage Treatment in Metastatic Biliary Tract Cancer (BTC) Patients Who Were Failed After Gemcitabine Containing Chemotherapy: A Phase II Single Arm Prospective Study

Biliary Tract Cancer

Korea, Republic of
Augusta University

Terminated

Feasibility and Safety Study of Nivolumab With Irinotecan for Small Cell Lung Cancer

Small Cell Lung Carcinoma | Small-cell Lung Cancer

United States
New Approaches to Neuroblastoma Therapy Consortium

Completed

131I-MIBG Alone VS. 131I-MIBG With Vincristine and Irinotecan VS131I-MIBG With Vorinostat (N2011-01)

Neuroblastoma

United States, Canada
University of Leeds

Completed

Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil

Colorectal Cancer

United Kingdom
EpicentRx, Inc.

Terminated

RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer (PAYLOAD) (PAYLOAD)

Metastatic Cancer | Advanced Cancer | Malignant Solid Tumor

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma

Neuroblastoma

United States
EpicentRx, Inc.

Completed

A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer (ROCKET)

Colorectal Neoplasms

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication

Schizophrenia

United States
Stony Brook University
University of Iowa; Ipsen; Barbara Ann Karmanos Cancer Institute

Completed

Phase I Trial HIPEC With Nal-irinotecan

Gastric Cancer | Colorectal Cancer | Mesothelioma | Pseudomyxoma Peritonei | Peritoneal Cancer | Mucinous Adenocarcinoma | Primary Peritoneal Carcinoma | Mucinous Tumor

United States
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Completed

Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD (ASCERTAINTRD)

Treatment Resistant Major Depressive Disorder

United States, Canada
Boehringer Ingelheim

Terminated

A Study to Test Different Doses of BI 1701963 in Combination With Irinotecan in People With Advanced Bowel Cancer With Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Mutation

Metastatic Colorectal Cancer (CRC)

China
Indiana University

Completed

A Phase II Study of Neoadjuvant FOLFIRINOX

Resectable Pancreatic Ductal Adenocarcinoma

United States
National Cancer Center, Korea

Completed

Pharmacogenomic Study for Providing Personalized Strategy to the Treatment of Non-small Cell Lung Cancer (NSCLC) IIIB/IV

Non Small Cell Lung Cancer

Korea, Republic of
Sumitomo Pharma Co., Ltd.

Completed

A Study of BBI608 Administrated With FOLFIRI + Bevacizumab in Adult Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Japan
National Cancer Institute, Naples

Completed

Intermittent or Continuous Panitumumab Plus FOLFIRI for RAS/B-RAF Wild-type Metastatic Colorectal Cancer (IMPROVE)

Colorectal Cancer Stage IV

Italy
National Cancer Center, Korea

Active, not recruiting

Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer

Small Cell Lung Carcinoma

Korea, Republic of
UNICANCER

Completed

Treatment After Irinotecan-based Frontline Therapy: Maintenance With Erbitux (in Patients wtRAS mCRC) (TIME)

Metastatic Colorectal Cancer

France
Biotech Pharmaceutical Co., Ltd.

Completed

Phase IIa Study of Nimotuzumab to Treat Colorectal Cancer

Colorectal Cancer

China
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; University of Colorado... and other collaborators

Completed

External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas

Brain Cancer

United States, Canada
Cancer Institute and Hospital, Chinese Academy...
Henan Cancer Hospital; Beijing Hospital; Jiangsu Cancer Institute & Hospital; Liaoning...

Completed

A Comparison of mXELIRI Regimen and FOLFIRI Combined Bevacizumab Regimen as First-line Chemotherapy Regimen for Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
The Skip Viragh Foundation

Active, not recruiting

Pancreatic Tumor Cell Vaccine (GVAX), Low Dose Cyclophosphamide, Fractionated Stereotactic Body Radiation Therapy (SBRT), and FOLFIRINOX Chemotherapy in Patients With Resected Adenocarcinoma of the Pancreas

Pancreatic Cancer

United States
Green Cross Corporation

Completed

A Study to Assess Safety, Efficacy, Immunogenicity, PK of GC1118 With Combination Chemotherapy

Metastatic Colorectal Cancer | Solid Tumor

Korea, Republic of
Athenex, Inc.

Completed

A Dose-regimen Finding Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oratecan in Subjects With Advanced Malignancies

Solid Tumor

United States
University Hospital, Antwerp
Universitair Ziekenhuis Brussel; General Hospital Groeninge; AZ Nikolaas; Erasme... and other collaborators

Active, not recruiting

Retrospective Study on the Efficacy and Tolerability of Liposomal Irinotecan (NALIRI)

Metastatic Pancreatic Ductal Adenocarcinoma

Belgium
University of Colorado, Denver
University of Kentucky

Completed

A Study of Eribulin in Combination With Oral Irinotecan for Adolescent and Young Adult Patients With Relapsed or Refractory Solid Tumors

Refractory Solid Tumors | Relapsed Solid Tumors

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma

Recurrent Ewing Sarcoma | Metastatic Ewing Sarcoma

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Completed

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | RAS Wild Type

United States
Oxford University Hospitals NHS Trust
University of Warwick; University of Birmingham; Janssen-Cilag Ltd.; Bloodwise

Completed

Optimising Renal Outcome in Myeloma Renal Failure (OPTIMAL)

Multiple Myeloma | Chronic Kidney Disease

United Kingdom
Robert C. Martin
University of Louisville

Completed

Drug-Eluting Bead, Irinotecan Therapy for Unresectable Intrahepatic Cholangiocarcinoma w/Concomitant Gemcitabine and Cisplatin or Carboplatin (DELTIC)

Unresectable Intrahepatic Cholangiocarcinoma

United States

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