Search clinical trials for: Switch

Total 1019 results

Merck Sharp & Dohme LLC

Terminated

Evaluation of Renal Function, Efficacy, and Safety When Switching From Tenofovir/Emtricitabine Plus a Protease Inhibitor/Ritonavir, to a Combination of Raltegravir (MK-0518) Plus Nevirapine Plus Lamivudine in HIV-1 Participants With Suppressed Viremia and Impaired Renal Function (MK-0518-284) (RANIA)

HIV Infections
MicroPort CRM
Sorin Group France SAS

Terminated

Efficacy of the ATP Switch Automatic Programming in Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy Defibrillator (CRT-D) Implanted Patients (ASAP)

Ventricular Arrythmias

France
Kasr El Aini Hospital

Unknown

Treatment of Freckles by Intradermal Tranexamic Acid Versus Q Switched KTP Laser.

Therapeutic Efficacy

Egypt
Novartis Pharmaceuticals

Completed

Assessment of Switching From Salmeterol/Fluticasone to Indacaterol/Glycopyrronium in a symtomaticCOPD Patient Cohort (FLASH)

COPD

India, South Africa, Egypt, Australia, Israel, Lebanon, Turkey, Philippines, Malaysia, Taiwan, Saudi Arabia
Novartis Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of Glycopyrronium or Indacaterol Maleate and Glycopyrronium Bromide Fixed-dose Combination Regarding Symptoms and Health Status in Patients With Moderate COPD Switching From Treatment With Any Standard COPD Regimen

COPD

Germany, Belgium, Poland, Romania, Italy, Spain, Estonia, Russian Federation, Austria, France, Slovakia, Czechia, Latvia, Lithuania, Greece, Hungary, United Kingdom, Portugal, Ireland, Norway, Slovenia, Denmark, Sweden
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Completed

Switching to Low Oxidant Content Cigarettes in Adult Smokers

Oxidative Stress | Nicotine

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMD (SAFARI)

Neovascular Age-related Macular Degeneration

Germany, United Kingdom
Astellas Pharma Inc

Completed

Study to Evaluate the Effects of Switching Different Strength Forms of FK949E in Bipolar Disorder Patients With Major Depressive Episodes

Bipolar Depression

Japan
Northern California Retina Vitreous Associates
Genentech, Inc.

Completed

Ranibizumab for Recalcitrant Wet Age-related Macular Degeneration in Eyes Previously Switched From Bevacizumab and/or Ranibizumab to Aflibercept. (RESCUE)

Recalcitrant Wet Age-related Macular Degeneration

United States
Abbott Medical Devices

Terminated

Optimal Sensing in Atrial Tachyarrhythmia's Study (OSAT)

Paroxysmal Atrial Fibrillation | Sick Sinus Syndrome

Netherlands
The Catholic University of Korea

Unknown

Treatment Efficacy and Safety of TDF-TAF Switch Study in South Korea

Chronic Hepatitis b

Korea, Republic of
Washington University School of Medicine
Bristol-Myers Squibb

Completed

Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole (BMS)

Schizophrenia | Type 2 Diabetes Mellitus

United States
Daiichi Sankyo, Inc.
Eli Lilly and Company

Completed

Pharmacodynamic Evaluation of Switching From Ticagrelor to Prasugrel in Subjects With Stable Coronary Artery Disease (SWAP-2)

Coronary Artery Disease

United Kingdom, United States
Novo Nordisk A/S

Completed

A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, Both With Insulin Aspart as Mealtime Insulin in Subjects With Type 1 Diabetes (SWITCH 1)

Diabetes | Diabetes Mellitus, Type 1

United States, Poland, Puerto Rico
Hoffmann-La Roche

Completed

MabRella Study: A Study to Evaluate the Safety of Switching From Intravenous to Subcutaneous Administration of Rituximab During First-Line Treatment for Lymphoma

Lymphoma, Non Hodgkin

Spain
The University of Hong Kong

Completed

Renoprotective Effects of Telbivudine in Chronic Hepatitis B

Chronic Kidney Diseases | Hepatitis B, Chronic

Hong Kong
Mundipharma Korea Ltd

Completed

An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion. (SWITCH)

Cancer Pain

Korea, Republic of
Gilead Sciences

Completed

Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults

HIV Infections | Acquired Immunodeficiency Syndrome | HIV-1

United States, Canada
Gilead Sciences

Completed

Efficacy, Safety, and Tolerability of Ledipasvir/Sofosbuvir (LDV/SOF) Treatment for HIV/HCV Co-infected Participants Who Switch to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) or Emtricitabine/Rilpivirine/Tenofovir Alafenamide (F/R/TAF) Prior to LDV/SOF HCV Treatment (Co-STARs)

HIV-1 Infection | HCV Infection

United States, Puerto Rico
Gilead Sciences

Completed

Safety and Efficacy of Switching From Regimens of ABC/3TC + a 3rd Agent to E/C/F/TAF Fixed-Dose Combination (FDC) in Virologically-Suppressed HIV 1 Infected Adults

HIV-1 Infection

Spain, United Kingdom, France, Germany, United States, Italy
University of Sydney
Allergan

Completed

Trial of Switching Between Intravitreal Bevacizumab (Avastin®)& Intravitreal Dexamethasone (Ozurdex™) for Persistent Diabetic Macular Oedema (SwitchDMO)

Diabetes | Diabetic Retinopathy | Diabetic Macular Edema | Diabetic Macular Oedema

Australia
Intarcia Therapeutics

Completed

Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide

Diabetes Mellitus, Type 2

United States
Giovanni Di Perri
University of Turin, Italy; University of Milan

Terminated

Bone Mineral Density Changes in HIV-positive Females With Osteopenia Switching to Raltegravir (RALBAT)

HIV Infection | Osteopenia

Italy
Amgen

Completed

Study to Assess the Impact on Calcium Levels When Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) Switch From Cinacalcet to Etelcalcetide

Hyperparathyroidism, Secondary

United States
University Hospital, Grenoble

Unknown

Electroencephalographic Monitoring in Patients Treated by Deep Brain Stimulation (EEG-DBS)

Psychiatric Disorder | Motor Disorders
Pfizer

Completed

Switchover Trial From Imiglucerase to Plant Cell Expressed Recombinant Human Glucocerebrosidase

Gaucher Disease

United Kingdom, Canada, Israel, United States, Australia, Spain
Novo Nordisk A/S

Completed

Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin (LIRA-SWITCH™)

Diabetes Mellitus, Type 2 | Diabetes

United States, Israel, Canada, Hungary, India, Spain, Puerto Rico
Bayer

Completed

Evaluation of Patient and Physician Reported Reasons for Switching Factor VIII Replacement Therapies (PARkER)

Hemophilia A

United States
University of Hawaii

Completed

Efficiency of Task Switching and Multi-tasking

Efficiency | Task Performance and Analysis

United States
GlaxoSmithKline

Terminated

Role of Early Versus Late Switch to Lapatinib-Capecitabine ((TYCO1))

Cancer

Brazil
Mahidol University

Completed

Efficacy of Rilpivirine-based Regimens as Switch Therapy From Nevirapine-based Regimens in HIV-infected Patients

Efficacy of Rilpivirine-based Regimens as Switch Therapy

Thailand
Sun Yat-sen University
Wenzhou Medical University; Huazhong University of Science and Technology; Beijing... and other collaborators

Unknown

Laser Peripheral Iridotomy Plus Laser Peripheral Iridoplasty for Primary Angle Closure

Glaucoma, Angle-Closure

China
Oregon Health and Science University

Completed

Neurocognitive and Metabolic Effects of Mild Hypothyroidism

Hypothyroidism

United States
Mackay Memorial Hospital

Completed

Comparison of Premixed Insulin With Basal-plus Insulin in Type 2 Diabetes Patients (COMPAR)

Diabetes

Taiwan
Kessler Foundation
New Jersey Commission on Brain Injury Research

Completed

Training Executive Functions to Facilitate Recovery Following Traumatic Brain Injury

Brain Injuries, Traumatic | Traumatic Brain Injury

United States
Memorial Sloan Kettering Cancer Center
Eli Lilly and Company; United States Department of Defense

Completed

Neoadjuvant Platinum-based Chemotherapy for Patients With Resectable , Non-small Cell Lung Cancer With Switch to Chemotherapy Alternative in Nonresponders (NEOSCAN)

Lung Cancer

United States
Cairo University

Unknown

Effect of Slopped Shoulder Implant Neck vs Conventional Implant Neck Design on Crestal Bone Level in the Maxilla

Missing Tooth
David Garcia Cinca
Fundacion Clinic per a la Recerca Biomédica

Unknown

Simplification Study of HIV-1 Infected Patients With Virological Suppression Under the Combination of Lamivudine (150 mg BID) Plus Raltegravir (400 mg BID) Switching to Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) : Roll-over Study of the RALAM (RALAM-RollOver)

HIV Infections | HIV Seropositivity | HIV-1-infection

Spain
University of British Columbia

Completed

Switch to Unboosted Atazanavir With Tenofovir Study (SUAT)

HIV Infection

Canada
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Completed

Switching to Reduced Oxidant or Nicotine Content Cigarettes in Smokers

Tobacco Smoking Behavior

United States
Védrines, Philippe, M.D.

Unknown

Addition of Azathioprine in IBD Patients With Immunogenic Failure (Comboswitch)

Clinical Failure After Switch

France
Azienda Ospedaliera San Gerardo di Monza
Gilead Sciences

Completed

Switching From Efavirenz/Atripla to Rilpivirine Among Patients With Neurocognitive or Neuropsychological Side Effects (SWEAR)

Quality of Life | HIV-1 Infection | Impaired Cognition | Poor Quality Sleep | Depression/Anxiety

Italy
Shenyang Northern Hospital

Completed

The Optimal Strategy of Switching From Clopidogrel to Ticagrelor in Patients With Complexity of Coronary Artery Disease

Coronary Artery Disease | Ticagrelor

China
Bayer
Regeneron Pharmaceuticals

Completed

Real Life of Aflibercept in France in Patients Refractory to Ranibizumab: Observational Study in Wet AMD (TITAN)

Wet Macular Degeneration

France
Willem Daniel Francois Venter
Medical Research Council, South Africa

Completed

Evaluation of Low-dose Darunavir in a Switch Study (DRV)

HIV Infections

South Africa
Yonsei University

Unknown

Switching From Tenofovir Disoproxi Fumarate to Tenofovir Alafenamide in Chronic Hepatitis B Patients With Antiviral Resistance

Hepatitis B | Antiviral Drug Adverse Reaction
R.J. Reynolds Vapor Company
RAI Services Company; Davita Clinical Research

Completed

Assess Biomarkers of Tobacco Exposure and Nicotine Pharmacokinetics in Smokers After a 5-Day In-Clinic Confinement Switch to an Electronic Cigarette or Nicotine Gum

Smoking

United States
VA Office of Research and Development

Completed

VA Augmentation and Switching Treatments for Improving Depression Outcomes (VAST-D)

Major Depressive Disorder

United States
Washington University School of Medicine
Pfizer

Terminated

The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart Disease

Tetralogy of Fallot | Transposition of the Great Vessels With an Arterial Switch | Single Ventricle With a Fontan Palliation

United States
Novartis Pharmaceuticals

Completed

Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's Dementia

Alzheimer's Dementia

Taiwan

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