Search clinical trials for: oral administration

Total 24212 results

Jochen Schmitt.
Merck Sharp & Dohme LLC

Completed

Economic Evaluation of Systemic Treatments for Moderate-to-severe Psoriasis

Psoriasis
GlaxoSmithKline

Completed

A Study Testing the Effect and Safety of Casopitant (GW679769) While Taking Warfarin in Healthy Human Volunteers

Nausea and Vomiting, Chemotherapy-Induced

United States
Sanofi

Completed

Activity and Safety of Oral Administration of SSR150106XB for the Reduction of Inflammation in Patients With Active Rheumatoid Arthritis (ACCORD-RA)

Rheumatoid Arthritis

Romania, Russian Federation, Ukraine, Bulgaria, Slovakia, Croatia, Czechia
University of California, Davis

Completed

Oral Administration of Colostrum to Premature Babies: Impact on the Oral Microbiota

Changes in the Oral Microbiota

United States
Mitchell S Elkind
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Neuroprotection With Statin Therapy for Acute Recovery Trial Phase 2 (NeuSTART2)

Stroke | Jaundice | Rhabdomyolysis

United States
GlaxoSmithKline

Completed

Effect of Omeprazole and Ritonavir on GSK2336805 Pharmacokinetics in Healthy Adults

Hepatitis C

United States
Asan Medical Center
Samsung Medical Center; Astellas Pharma Korea, Inc.; Severance Hospital; Kyung...

Completed

Correlation Between Change of HbA1c, Urinary Glucose Excretion and Other Factors in Patients Treated With Ipragliflozin

Type 2 Diabetes Mellitus

Korea, Republic of
Onconova Therapeutics, Inc.

Completed

Oral Rigosertib for Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Anal Squamous Cell Carcinoma | Cervical Squamous Cell Carcinoma | Skin Squamous Cell Carcinoma | Lung Squamous Cell Carcinoma | Penile Squamous Cell Carcinoma

United States
Eli Lilly and Company

Completed

Disposition of 14C-LY3009104 Following Oral Administration in Healthy Human Subjects

Healthy Volunteers

United States
Michigan State University
National Cancer Institute (NCI)

Completed

Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR

Melanoma | Leukemia | Breast Neoplasms | Prostatic Neoplasms | Colorectal Neoplasms

United States
Stanford University

Terminated

Assessment of Zegerid on Esophageal pH in Patients With Barrett's Esophagus

Gastroesophageal Reflux | Barrett Esophagus

United States
Hoffmann-La Roche

Terminated

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7020322 Following Oral Administration in Healthy Participants and Chronic Hepatitis B Patients

Hepatitis B, Chronic

Hong Kong, Taiwan, New Zealand
Genentech, Inc.

Completed

An Absolute Bioavailability Study in Healthy Participants Comparing Oral to Intravenous Administration of GDC-0973 (Cobimetinib)

Healthy Volunteers
University of Aarhus
Aarhus University Hospital

Terminated

Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration

Invasive Aspergillosis

Denmark
HaEmek Medical Center, Israel

Completed

To Compare the Efficacy and Patients' Satisfaction for the Treatment of Post Cesarean Pain of Two Protocols: Oral Medications in Fixed Time Interval Administration Versus Spinal Morphine

Post Cesarean Pain Management

Israel
UMC Utrecht

Completed

Brain Activity and Hormonal Changes During Food Administration

Appetite Regulation

Netherlands
Milton S. Hershey Medical Center

Completed

Continuous Administration of Oral Contraceptive, Primary Dysmenorrhea (Dysmenorrhea)

Dysmenorrhea

Croatia
National Institute of Allergy and Infectious Diseases...

Completed

Auranofin PK Following Oral Dose Administration

Amoebiasis

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP14012 After Oral Administration in Healthy Male Volunteers

Healthy

Korea, Republic of
Universidad Autonoma de Baja California

Completed

The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo (PreOp)

Pulpitis - Irreversible

Mexico
National Cancer Institute (NCI)

Terminated

Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IVA Laryngeal Squamous Cell Carcinoma | Stage... and other conditions

Canada, United States
Sanwa Kagaku Kenkyusho Co., Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Effect of Topiroxostat on Urinary Albumin Excretion Early Stage Diabetic Nephropathy and Hyperuricemia With or Without Gout (UPWARD)

Diabetic Nephropathy

Japan
Dr. R. Pfleger Chemische Fabrik GmbH

Completed

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Pharmacokinetics | Drug Interaction Potentiation | Inhibition Enzyme
Pfizer

Completed

A Bioequivalence Study Comparing A Fixed Dose Combination Formulation Of Myrin P Forte That Contains Rifampicin, Isoniazid, Ethambutol And Pyrazinamide Per Tablet To An Equivalent Dose Of Single Drug Reference Preparations Of Similar Combination Following Oral Administration In Healthy Adults

Healthy Volunteers

Singapore
GlaxoSmithKline

Completed

To Test 2 Doses of GSK Biologicals' Oral Live Attenuated Human Rotavirus (HRV) Vaccine in Healthy Infants in Co-administration With Specific Childhood Vaccines

Infections, Rotavirus

Finland, Germany, Spain, Italy, France, Czech Republic
AstraZeneca

Completed

A Bioavailability Study With Alternate Methods of Administration of Naloxegol Tablets, and Solution

Healthy Subjects | Bioavailability

Germany
Astellas Pharma Inc

Completed

Study to Evaluate the Effect of Food Intake on the Plasma Concentration Changes of Quetiapine After Oral Administration of FK949E in Healthy Volunteers

Healthy | Plasma Concentration Change of Quetiapine

Japan
University Hospital Inselspital, Berne

Completed

Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia

Epidural Analgesia | Radical Cystectomy | Postoperative Pain Management | Oral Oxycodone With/Without Naloxone | Return of the Bowel Function

Switzerland
Janssen Research & Development, LLC

Completed

A Crossover Study to Evaluate the Relative Oral Bioavailability and Food Effect After Single Dose Administration of JNJ-54861911 Tablet in Healthy Elderly Participants

Healthy

Belgium
Novartis Pharmaceuticals

Completed

A Phase II Study to Evaluate Efficacy and Safety of Dovitinib (TKI258) in Advanced Scirrhous Gastric Carcinoma Patients

Neoplasms | Neoplasms by Site | Stomach Neoplasms | Stomach Diseases | Adenocarcinoma, Scirrhous | Linitis Plastica

Japan
Takeda
EA Pharma Co., Ltd.

Completed

A Phase II/III, Double-blind, Parallel Group Comparative Study of Oral Administration of NE-58095 Tablets

Involutional Osteoporosis

Japan
University of Roma La Sapienza

Completed

Efficacy of Preoperative Administration of Paracetamol-codeine on Pain Following Impacted Mandibular Third Molar Surgery

To Control Pain After Third Molar Surgery
Novo Nordisk A/S

Completed

Effect of Oral Contraceptives After Administration of Semaglutide in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Germany
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Acceptability of Less Harmful Alternatives to Cigarettes

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
IlDong Pharmaceutical Co Ltd

Completed

Clinical Trial to Compare the Pharmacokinetics of TAH Tablet in Comparison to the Co-administration of Telmisartan, Amlodipine and Hydrochlorothiazide in Healthy Male Volunteers

Healthy

Korea, Republic of
Novo Nordisk A/S

Completed

Influence on the Effect of an Oral Contraceptive Drug After Administration of Liraglutide in Postmenopausal Women

Diabetes Mellitus, Type 2 | Diabetes

Sweden
Justin Fraser

Completed

Superselective Administration of VErapamil During Recanalization in Acute Ischemic Stroke (SAVER-I)

Ischemic Stroke

United States
University Hospital, Tours
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Infliximab and Methotrexate in Ankylosing Spondylitis (SPAXIM)

Ankylosing Spondylitis

France
Novo Nordisk A/S

Completed

Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs

Diabetes Mellitus, Type 2 | Diabetes

Morocco, Tunisia, Algeria, South Africa, Egypt
SocraTec R&D GmbH
SocraMetrics GmbH

Completed

Ibuprofen Bioavailability Trial With Oral Single Dose Administration.

Bioequivalence

Germany
Sheba Medical Center

Completed

Chewing Versus Traditional Oral Administration of Ticagrelor in STEMI Patients

ST Elevation Myocardial Infarction | Acute Coronary Syndromes

Israel
University Medicine Greifswald

Completed

Oral Pharmacokinetics of Sulfasalazine, Paracetamol, Fexofenadine and Valsartan Using Different Administration Mediums

Pharmacokinetics | Magnetic Resonance Imaging | Administration, Oral
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Pharmacokinetics of Rilpivirine/Tenofovir/Emtricitabine After a Single-Oral Administration in Healthy Japanese Adult Male Participants

Healthy

Japan
SocraTec R&D GmbH
SocraMetrics GmbH

Completed

Characterisation of Relative Bioavailability With Bioequivalence Assessment of Deferiprone Tablets After Oral Single Dose Administration

Bioequivalence

Germany
Medical University of Vienna
University of Natural Resources and Life Sciences, Vienna, Austria

Completed

Oral Administration of Four Lactobacillus Species Preparation to Improve the Quality of the Neovaginal Flora in Male to Female Transsexual Patients

Reduction or Absence of Lactobacilli in Neovaginal Flora

Austria
Central Clinical Hospital w/Outpatient Health Center...

Unknown

Effectiveness and Safety of Method of Maxilla Alveolar Process Reconstruction Using Synthetic Tricalcium Phosphate and Autologous MMSCs

Alveolar Bone Loss | Alveolar Bone Atrophy | Partially Edentulous Maxilla

Russian Federation
Sidney Kimmel Cancer Center at Thomas Jefferson...

Terminated

Pilot Trial of Intravenous Vitamin C in Refractory Non-Hodgkin Lymphoma (NHL)

Non-Hodgkin Lymphoma

United States
University of Saskatchewan
Canadian Institutes of Health Research (CIHR)

Completed

Administration of Oral Contraceptives at Different Times of the Follicular Phase of the Menstrual Cycle

Contraception

Canada
University of California, Los Angeles

Completed

Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1) (NF1)

Neurofibromatosis 1

United States
Hoffmann-La Roche

Completed

A Study on the Effect of Renal Function on the Pharmacakokinetics of RO5024048 (Parent of Prodrug RO5024048) Following Multiple Oral Dose Administration of RO5024048

Healthy Volunteer

New Zealand, United States

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