Search clinical trials for: skin safety

Total 91514 results

NYU Langone Health

Recruiting

Safety of the Herpes Zoster Subunit Vaccine in Lupus

Systemic Lupus Erythematosus

United States
Inion Oy

Recruiting

Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation

Fractures, Bone | Foot Deformities | Ankle Fractures | Hallux Valgus | Hallux Rigidus | Fracture of Foot | Lisfranc Fracture | Metatarsalgia | Lisfranc Injury | Deformity, Foot | Calcaneus Fracture | Talus Fracture | Medial Malleolus Fracture | Navicular Fracture | Foot Fracture | Foot Injury | Feet Deformity Tarsus | Deformity... and other conditions

Finland
UNICANCER
Gilead Sciences

Recruiting

Safety and Efficacy Analysis of an Antibody Associated With a Chemotherapy for Patients With a Triple Negative Metastatic Breast Cancer (ISIdE)

Metastatic Breast Cancer | Triple Negative Breast Cancer

France
Nantes University Hospital
University Hospital, Angers; Rennes University Hospital; Clinique de l'Anjou

Recruiting

SARS Cov 2 Vaccination in Adolescents With Juvenile Idiopathic Arthritis (VACOVAJI)

SARS Cov 2 Vaccination in Adolescents With Juvenile Idiopathic Arthritis

France
Novartis Pharmaceuticals

Recruiting

A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced Cancers

Carcinoma, Renal Cell | Carcinoma, Non-Small-Cell Lung | Nasopharyngeal Carcinoma | Carcinoma, Ovarian Epithelial | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Anal Cancer | Cutaneous Melanoma | Esophagogastric Cancer | Carcinoma, Thymic | High Microsatellite...

Italy, Spain, Singapore, Germany, Taiwan, Japan, Canada, Hong Kong, United States
Biocomposites Ltd
MCRA

Recruiting

A Feasibility Trial to Investigate the Safety and Between-group Effect Size of STIMULAN VG and Standard of Care (SoC) in Participants With Diabetic Foot Osteomyelitis of the Forefoot. (BLADE-VG2)

Diabetic Foot Osteomyelitis

United States
Southwest Hospital, China

Recruiting

Efficacy and Safety of NeuroEndoscopic Surgery for IntraCerebral Hemorrhage (NESICH)

Intracerebral Hemorrhage Basal Ganglia

China
Seoul National University Hospital

Not yet recruiting

Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors After a CDK4/6 Inhibitor (Post-CDK)

Advanced Breast Cancer

Korea, Republic of
Katarzyna Kotulska

Recruiting

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex (RaRE-TS)

Tuberous Sclerosis Complex

Poland
Biogen

Recruiting

A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST)

Subacute Cutaneous Lupus Erythematosus | Chronic Cutaneous Lupus Erythematosus

United States, Italy, Korea, Republic of, Taiwan, Argentina, Chile, Spain, Canada, Serbia, France, Germany, Japan, Brazil, United Kingdom, Bulgaria, Portugal, Switzerland, Philippines, Saudi Arabia, Sweden, Mexico, Poland, Hungary, Puerto... and more
UnicoCell Biomed CO. LTD

Recruiting

Efficacy and Safety of ELIXCYTE Intra-articular Injection in Subject With Knee Osteoarthritis

Knee Osteoarthritis

Taiwan
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥2 Years to <12 Years of Age With Uncontrolled Chronic Spontaneous Urticaria (CSU) (LIBERTY-CSU CUPIDKids)

Chronic Spontaneous Urticaria

United States, Canada, Japan
Guangzhou Henovcom Bioscience Co. Ltd.

Recruiting

A Study to Evaluate the Safety, Tolerability, PK and PD of HNC364 Injectable Suspension

Parkinson's Disease

United States
argenx

Recruiting

A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy. (ALKIVIA)

Myositis | Dermatomyositis | Polymyositis | Antisynthetase Syndrome | Immune-Mediated Necrotizing Myopathy | Active Idiopathic Inflammatory Myopathy

United States, Germany, Spain, Korea, Republic of, Austria, Turkey, Lithuania, Australia, Thailand, Serbia, Poland, Italy, France, Netherlands, Argentina, United Kingdom, Georgia, Belgium, Bulgaria, Canada, Cyprus, Denmark, Greece, Hu... and more
Quoin Pharmaceuticals

Recruiting

Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome

United States
Institut Paoli-Calmettes
GlaxoSmithKline

Not yet recruiting

A Phase 1b/2 Trial Evaluating Safety and Efficacy of CAPecitabine in Combination With Ni-rapaRIb in HER2-negative Advanced Breast canCEr (CAPRICE)

Breast Cancer
Fudan University
Zhejiang Cancer Hospital; Huashan Hospital; Henan Cancer Hospital; Hunan Cancer... and other collaborators

Not yet recruiting

Patient-Reported Outcome and Safety Between Preoperative and Postmastectomy Radiotherapy in DIEP Flap Reconstruction (CAPPELLA)

Breast Cancer

China
Novartis Pharmaceuticals

Recruiting

An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib

Chronic Spontaneous Urticaria

United States, Korea, Republic of, Spain, France, Germany, Bulgaria, United Kingdom, China, Hungary, Czechia, Turkey, Argentina, Colombia, Italy, Denmark, Japan, Taiwan, Australia, Singapore, Switzerland, Russian Federation, Thailand and more
Q32 Bio Inc.

Recruiting

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Atopic Dermatitis

United States
Fujian Medical University Union Hospital

Recruiting

Efficacy and Safety of Astragalus for Non-motor Symptoms of α-Synucleinopathy

Parkinsonism

China
KalVista Pharmaceuticals, Ltd.

Recruiting

An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

Hereditary Angioedema

United States, Bulgaria, France, Greece, Hungary, Israel, Italy, Netherlands, New Zealand, North Macedonia, Poland, Spain, United Kingdom, Australia, Germany, South Africa, Austria, Portugal, Slovakia, Romania, Canada, Saudi Arabia, Japa...
The Affiliated Hospital of Qingdao University
Qingdao Sino-Cell Biomedicine Co.,Ltd.

Not yet recruiting

Study on the Safety and Efficacy of Autogenous Tumor Infiltrates Lymphocytes for the Treatment of Advanced Breast Cancer

Breast Cancer

China
Kira Pharmacenticals (US), LLC.

Not yet recruiting

Study to Evaluate Safety, Tolerability and Pharmacodynamics of KP104 in Participants With Thrombotic Microangiopathy Secondary to Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Qilu Hospital of Shandong University

Recruiting

Efficacy and Safety of Pirfenidone in CTD-ILD

Connective Tissue Diseases | Interstitial Lung Disease | Pirfenidone

China
Church & Dwight Company, Inc.
EVAMED

Recruiting

Pilot Study to Assess Performance and Safety of SULFEX 13081.22 Nasal Spray in Patients With Dry or Irritated Nose

Dry Nose | Nose Irritation

France
Celltrion

Recruiting

To Compare Pharmacokinetics, Efficacy, and Safety of CT-P17 With Humira in Patients With Moderate to Severe Chronic Plaque Psoriasis

Moderate to Severe Chronic Plaque Psoriasis

Estonia
Sanofi

Recruiting

Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials (RIVER-AD)

Dermatitis Atopic

Canada, United States, Australia, Bulgaria, Czechia, Germany, Hungary, Japan, Poland, Spain, Taiwan, United Kingdom
Valo Therapeutics Oy

Recruiting

START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer

Colorectal Cancer | Non-Small Cell Lung Cancer | Melanoma (Skin) | Myxoid Liposarcoma | Synovial Sarcoma | Triple-Negative Breast Cancer

Germany
Celltrion

Not yet recruiting

A Study to Compare Efficacy and Safety of CT-P47 and RoActemra in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Shanghai Henlius Biotech

Recruiting

To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

Extensive Stage Small Cell Lung Cancer

United States
Xinhua Zhang, MD
Xijing Hospital; Chongqing University Cancer Hospital; Xiangya Hospital of Central... and other collaborators

Not yet recruiting

A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal Tumors

Gastrointestinal Stromal Tumors | Unresectable Solid Tumor | Recurrent Metastatic Malignant Neoplasm
Genentech, Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of RO7303509 in Participants With Systemic Sclerosis

Systemic Sclerosis

Belgium, United States, Spain, France, Portugal, Serbia, Germany, United Kingdom, Israel, Poland, Argentina, Puerto Rico
Sinovac (Dalian) Vaccine Technology Co., Ltd.

Recruiting

Immunogenicity, Safety and Protective Effect of Live Attenuated Varicella Vaccine and Study on Antibody Level and Etiology of Varicella Zoster Virus

Varicella

China
Essentia Health
Minnesota Cancer Clinical Trials Network

Recruiting

Safety of Extending The Routine Flushing Of Implanted Port Devices From 4 Weeks To 12

Maintenance of Implanted Port Devices

United States
ICM Co. Ltd.

Not yet recruiting

A Study Evaluating the Safety, Tolerability, and Activity of ICM-203 in Subjects With Knee Osteoarthritis.

Osteoarthritis, Knee
Zhejiang Provincial People's Hospital

Recruiting

Efficacy and Safety of Abatacept Combined With JAK Inhibitor for Refractory Rheumatoid Arthritis

Rheumatoid Arthritis | Treatment Compliance | Abatacept

China
Guang'anmen Hospital of China Academy of Chinese...

Recruiting

Efficacy and Safety Evaluation of Acupoint Application in the Treatment of Knee Osteoarthritis Joint Pain

Knee Osteoarthritis

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Phase II/III Study of Efficacy and Safety of SHR7280 Tablets in Subjects With Menorrhagia With Uterine Fibroids

Uterine Fibroids With Menorrhagia

China
China Medical University Hospital

Recruiting

To Evaluate the Efficacy and Safety of Amorphous Calcium Carbonate in RA Patient With Osteopenia or Osteoporosis

Rheumatoid Arthritis | Osteopenia or Osteoporosis

Taiwan
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Fudan University

Not yet recruiting

A Clinical Study of the Efficacy and Safety of Chidamide in Combination With Camrelizumab and Carboplatin or Capecitabine in the Second and Third Line Treatment of Relapsed/Metastatic Triple-negative Breast Cancer

Triple-negative Breast Cancer

China
Shenzhen Kangzhe Pharmaceutical Co., Ltd.
LanZhou University; Beijing Friendship Hospital; The Third Affiliated Hospital... and other collaborators

Recruiting

A Multicentre Study to Explore the Efficacy and Safety of Mucopolysaccharide Polysulfate Cream in Patients With Eczema

Eczema

China
Priovant Therapeutics, Inc.

Recruiting

A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis (VALOR)

Dermatomyositis

United States, Belgium, Germany, Hungary, Israel, Italy, Netherlands, Portugal, Korea, Republic of, Bulgaria, Poland, Romania, Czechia, Taiwan, Chile, Mexico, Turkey, Serbia, Spain, United Kingdom, Canada, Argentina
Kamari Pharma Ltd

Recruiting

Study Designed to Evaluate Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita Diseases

Pachyonychia Congenita | Punctate Palmoplantar Keratoderma Type 1

Israel
BioNTech SE

Recruiting

A Clinical Trial in Healthy Volunteers to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions

Genital Herpes Simplex Type 2

United States
Cancer Institute and Hospital, Chinese Academy...
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

The Efficacy and Safety of Dalpiciclib Plus Endocrine Therapy in HR-positive / HER2-negative Advanced Breast Cancer Patients With Visceral Crisis

Advanced Breast Cancer

China
Integrative Skin Science and Research
Soovu Labs Inc.

Not yet recruiting

Safety of Pulsing Heating Device Use on the Skin

Pain

United States
Biopharma Plasma LLC

Recruiting

Intravenous Immunoglobulin (IVIG, Bioven) Efficacy and Safety in Chronic Primary Immune Thrombocytopenia (ITP) in Adults

Primary Immune Thrombocytopenia

Ukraine
GC Biopharma Corp

Recruiting

A Study to Evaluate the Safety, Tolerability, PK and PD of Intracerebroventricular GC1123 in Patients With MPS Ⅱ

Mucopolysaccharidosis II | Hunter Syndrome

Korea, Republic of

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