Search clinical trials for: Front-line treatment

Total 63394 results

Eunice Kennedy Shriver National Institute of Child...

Completed

Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain

Chronic Pain | Amputation

United States
J. Uriach and Company

Terminated

Efficacy Vulvovaginitis Candida

Candidiasis Vulvaginitis
Olympic Medical

Completed

CoolCap Trial, Treatment of Perinatal Hypoxic-Ischemic Encephalopathy

Neonatal Hypoxic-Ischemic Encephalopathy (HIE)

United States, Canada, United Kingdom, New Zealand
Abbott

Completed

A Simplified Kaletra® (Lopinavir/Ritonavir)-Based Therapy Versus a Sustiva® (Efavirenz)-Based Standard of Care in Previously Non-Treated HIV-Infected Subjects

HIV Infections

United States
elbion AG

Terminated

ELB139 Given Orally to Patients With Concurrent Panic Disorder, Challenged by CO2 Inhalation After a Single Dose and One Week of Treatment

Panic Disorder

Germany, Netherlands
Nordic Myeloma Study Group

Unknown

Fludarabine Added to Induction Treatment in Untreated Multiple Myeloma Patients

Multiple Myeloma

Denmark
OraPharma

Completed

Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis

Periodontitis

United States
Peking University

Unknown

ACEi/ARB Alone Versus ACEi/ARB Plus Steroids in the Treatment of Primary IgA Nephropathy, a RCT

Glomerulonephritis, IGA
University of Sao Paulo

Completed

Trial of Acupuncture Added to Usual Treatment for Fibromyalgia

Fibromyalgia

Brazil
The New York Academy of Medicine
Public Health Solutions

Unknown

Outcome Evaluation of Minority AIDS Initiative Programs in the New York EMA

HIV Infections

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Comparison of 2 Antifungal Treatment (Empirical Versus Pre-Empirical) Strategies in Prolonged Neutropenia

Malignant Hemopathy | Duration of Neutropenia Following Chemotherapy > 10 Days

France
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

Double-Blind Trial of Miglitol in Type 2 Diabetic Patients With Insulin Treatment

Type 2 Diabetes Mellitus

Japan
Herlev Hospital

Unknown

Treatment With Local PPARgamma Ligand in Distal Ulcerative Colitis

Ulcerative Colitis

Denmark
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

Open Trial of Miglitol in Type 1 Diabetic Patients With Insulin Treatment

Type 1 Diabetes Mellitus

Japan
Lampiris, Harry W., M.D.
Abbott

Unknown

High Dose Ritonavir/Lopinavir Liquid Formulation in Salvage Therapy for Protease Inhibitor Resistant HIV Disease

HIV | AIDS

United States
Enanta Pharmaceuticals, Inc

Unknown

Comparative Study of EDP-420 Versus Another Antibiotic in the Treatment of Community Acquired Pneumonia

Community Acquired Pneumonia

United States
University of Alberta
Alberta Heritage Foundation for Medical Research; Royal Alexandra Hospital

Completed

Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients

Osteoporosis | Hip Fracture

Canada
Eli Lilly and Company

Terminated

Gemzar (Gemcitabine) and Alimta (Pemetrexed) in the Treatment of Patients With Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer

Ovarian Cancer | Peritoneal Cancer

United States
Weill Medical College of Cornell University

Terminated

Treatment With ATRA-IV and Depakote in Patients With Advanced Solid Tumor Malignancies

Solid Tumor Malignancies

United States
The University of New South Wales
Ocean Nutrition; Your Health Inc.; Sphere Healthcare

Unknown

A Study of Omega-3 as a Treatment for Major Depression

Major Depression | Dysthymia

Australia
Rigshospitalet, Denmark

Unknown

Removal of Protein Bound Uremic Toxins by Modified Plasma Separation and Adsorption Combined With Hemodialysis

Uremia

Denmark
The University of New South Wales
Ocean Nutrition; Your Health Inc.; Sphere Healthcare

Unknown

A Study of Omega-3 as an Augmentor of Antidepressant Treatment for Major Depression

Major Depression

Australia
International Union Against Tuberculosis and Lung...
United States Agency for International Development (USAID)

Unknown

Multicenter Trial for the Evaluation of a Fixed Dose Combined Tablet for the Treatment of Pulmonary Tuberculosis

Tuberculosis

Algeria, Bolivia, Colombia, Guinea, Mozambique, Nepal, Peru, Tanzania, Vietnam
Centro de Estudos Mário César de Rezende

Unknown

Perioperative Hemodynamic Optimization in High-Risk Patients Using Less-Invasive Monitoring Methods

Postoperative Care

Brazil
Dutch Epilepsy Clinics Foundation

Unknown

Second-Line Treatment Choice for Epilepsy

Adults With Tonic Clonic Seizures and/or Partial Seizures

Netherlands
University of New Mexico
Pfizer

Completed

Study of Sildenafil for Treatment of SSRI-Antidepressant Sexual Dysfunction in Women

Depression | Sexual Dysfunction

United States
Biogen

Terminated

Safety and Efficacy of Zevalin in the Treatment of Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United States
Hamilton Health Sciences Corporation
Eli Lilly and Company

Completed

Olanzapine in the Treatment of Hair Pulling (Trichotillomania)

Trichotillomania

Canada
Hvidovre University Hospital

Unknown

Prophylactic Antibiotic Treatment During Vaginal Repair

Cystocele | Uterine Prolapse | Rectocele | Enterocele

Denmark
Ain Shams University
National Institute of Allergy and Infectious Diseases (NIAID); Beth Israel... and other collaborators

Completed

Timing and Duration of Acute Hepatitis C Treatment

Hepatitis C

Egypt
Charite University, Berlin, Germany

Unknown

Prednisolone in Active Ankylosing Spondylitis (AS)

Ankylosing Spondylitis

Germany
Aga Khan University

Unknown

Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants

Sepsis | Bacterial Infection | Infant, Newborn

Pakistan
Odense University Hospital
University of Southern Denmark

Completed

Treatment With Lactobacillus Rhamnosus and Lactobacillus Acidophilus for Patients With Active Colonic Crohn's Disease.

Crohn's Disease

Denmark
Hamamatsu University
Yokoyama Foundation for Clinical Pharmacology

Unknown

Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori

Gastritis | Helicobacter Infections | Gastric Ulcer | Duodenal Ulcer

Japan
Odense University Hospital
University of Southern Denmark; Crohn's and Colitis Foundation

Completed

Treatment of Ulcerative Colitis With a Combination of Lactobacillus Rhamnosus and Lactobacillus Acidophilus.

Ulcerative Colitis

Denmark
MTmedical Institute of Health
The University of Texas Health Science Center at San Antonio; BioMonde Preparations...

Unknown

4-Methylumbelliferone as a Treatment for Chronic HBV/HCV

Chronic Hepatitis B | Chronic Hepatitis C

United States
NYU Langone Health
Genentech, Inc.

Completed

Efficacy and Safety of Efalizumab in the Treatment of Moderate-Severe Hydradenitis Suppurativa

Hidradenitis Suppurativa

United States
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery and Intraperitoneal Chemohyperthermia

Endocrine Tumors | Colon Tumors | Rectum Tumors | Appendix Tumors | Peritoneum Tumors

France
Hamilton Health Sciences Corporation

Completed

Integrating Family Medicine and Pharmacy to Advance Primary Care Therapeutics

Pain | Hypertension | Diabetes | Constipation | Hyperlipidemia

Canada
University of Rochester

Completed

Feasibility of Treatment of Cancer Involving the Liver With High Dose Radiation

Neoplasm Metastasis | Liver Neoplasms

United States
QuatRx Pharmaceuticals Company

Completed

Safety and Efficacy Study of Two Dose Regimens of Becocalcidiol in the Treatment of Plaque-Type Psoriasis

Psoriasis

United States
Hopital Antoine Beclere

Unknown

Evaluation of Therapeutic Strategies for Treatment of Ectopic Pregnancies (EP) and Evaluation of Subsequent Fertility

Tubal Pregnancy

France
University of North Carolina
Robert Wood Johnson Foundation

Completed

A Study of the Cost Effectiveness of Generalist Care Managers for Depression Treatment in Medicaid Recipients

Major Depressive Disorder

United States
The University of Queensland
US Department of Veterans Affairs

Unknown

Evaluation of a MCYI as Adjunct to Psychiatric Treatment for Vietnam Veterans With PTSD - RCT

Depression | Posttraumatic Stress Disorder
National Eye Institute (NEI)

Completed

Early Treatment Diabetic Retinopathy Study (ETDRS)

Diabetic Retinopathy | Blindness
Azienda Ospedaliera San Giovanni Battista

Completed

Hospitalization at Home of Elderly Patients With Exacerbated COPD

COPD Exacerbation
Finnish Institute for Health and Welfare
Finnish Foundation for Alcohol Studies

Completed

Efficacy Study of Memantine Hydrochloride and Escitalopram for the Treatment of Co-Morbid Depression and Alcoholism.

Depression | Alcoholism

Finland
Sheba Medical Center
H. Lundbeck A/S

Unknown

Study of Escitalopram Versus Placebo in the Treatment of Depressive Syndrome in Alzheimer's Disease, Vascular Dementia, and Mixed Vascular and Alzheimer's Dementia

Depressive Syndrome

Israel
Sheba Medical Center

Unknown

TCV -01-002: T-Cell Vaccination in the Treatment of Probable Multiple Sclerosis

Multiple Sclerosis

Israel
Pontificia Universidad Catolica de Chile
Sociedad Chilena de Pediatría

Unknown

Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams

Respiratory Distress Syndrome

Chile

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