Clinical Trials Sponsored by Vanguard Research Group

Total 1348 results

Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Trial With Vinorelbine and Gemcitabine Versus Docetaxel and Gemcitabine in Patients With Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

Greece
European Organisation for Research and Treatment...
Swiss Group for Clinical Cancer Research; Swedish Breast Cancer Group; Anglo...

Completed

Biomarker (p53 Gene) Analysis and Combination Chemotherapy Followed by Radiation Therapy and Surgery in Treating Women With Large Operable or Locally Advanced or Inflammatory Breast Cancer

Breast Cancer

France, Switzerland, Poland, Sweden, Belgium, Netherlands, United Kingdom, Portugal, Slovenia
European Organisation for Research and Treatment...
Eastern Cooperative Oncology Group; Southwest Oncology Group; Scandinavian Sarcoma...

Completed

Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma

Sarcoma | Kidney Cancer | Ovarian Cancer | Metastatic Cancer | Endometrial Cancer | Pheochromocytoma

Sweden
Trans Tasman Radiation Oncology Group
European Organisation for Research and Treatment of Cancer - EORTC; NCIC Clinical... and other collaborators

Active, not recruiting

Radiation Doses and Fractionation Schedules in Non-low Risk Ductal Carcinoma In Situ (DCIS) of the Breast (DCIS)

Carcinoma, Ductal, Breast

United Kingdom, Netherlands, Ireland, Switzerland, Australia, Singapore, New Zealand, Belgium, Canada, Italy, France
Galician Research Group on Digestive Tumors
LEO Pharma

Recruiting

TINzaparin Prophylaxis in Patients With Metastatic Colorectal Cancer (PROTINCOL)

Thromboembolism | Colorectal Cancer Metastatic

Spain
SOLTI Breast Cancer Research Group
Roche Pharma AG

Recruiting

Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients (IPATHER)

Metastatic Breast Cancer

Spain
Spanish Oncology Genito-Urinary Group
Adknoma Health Research

Completed

SOGUG-AVELUMAB_RWD (SOGUG)

Metastatic Urothelial Carcinoma

Spain
Canadian Cancer Trials Group
Ottawa Hospital Research Institute

Active, not recruiting

MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine With Transgenic MAGE-A3 Insertion in Incurable MAGE-A3-Expressing Solid Tumours

Advanced/Metastatic Solid Tumours

Canada
SOLTI Breast Cancer Research Group
Daiichi Sankyo, Inc.

Active, not recruiting

NeoadjuVAnt muLti-agENT Chemotherapy or Patritumab Deruxtecan With or Without endocrINE Therapy for High-risk HR+/HER2- Breast Cancer - VALENTINE Trial (VALENTINE)

Breast Cancer

Spain
Versartis Inc.
Premier Research Group plc

Terminated

Open-label Extension Study to Evaluate the Safety of Long-term Twice-monthly Administration of Somavaratan in Adult Growth Hormone Deficiency (AGHD)

Adult Growth Hormone Deficiency (AGHD)
Spanish Breast Cancer Research Group
Bristol-Myers Squibb

Completed

Dasatinib In Combination With Trastuzumab And Paclitaxel In First Line Treatment Of Her2-Positive MBC Patients

Metastatic Breast Cancer

Spain
Spanish Breast Cancer Research Group
Roche Farma, S.A

Completed

Evaluation of Degree of Conversion of HER2 Receptor Between Primary Breast Cancer and Metastasis

Breast Cancer

Spain
SOLTI Breast Cancer Research Group
Radius Health, Inc.

Completed

Elacestrant in Preoperative Setting, a Window of Opportunity Study (ELIPSE)

Breast Cancer | Hormone Receptor Positive Breast Carcinoma

Spain
Aptinyx
Massachusetts General Hospital; Premier Research Group plc

Completed

Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder

Post-Traumatic Stress Disorder

United States
Spanish Breast Cancer Research Group
Hoffmann-La Roche

Terminated

Benefit of Adding Trastuzumab to Second Line Chemotherapy in Breast Cancer Patients Previously Treated With Trastuzumab

Breast Cancer

Spain
Kantonsspital Graubuenden
Swiss Group for Clinical Cancer Research

Completed

SBRT for Oligometastatic Lymph Node Recurrence in Prostate Cancer: a Single Institution Experience

Prostate Cancer | Prostate Cancer Recurrent | Lymph Node Metastases

Switzerland
Price Vision Group
Cornea Research Foundation of America

Terminated

Cross Linking for Treatment of Corneal Infection

Infectious Keratitis

United States
Hellenic Oncology Research Group
University Hospital of Crete

Unknown

Adjuvant Therapy(3 vs. 6 Months) With the FOLFOX 4 or XELOX for Stage II or Stage III Colon Cancer

CRC

Greece
Kinex Pharmaceuticals Inc.
Atlantic Research Group

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oraxol in Subjects With Advanced Malignancies

Solid Tumor

United States
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Metronomic Vinorelbine and Bevacizumab in Patients With Non Small Cell Lung Cancer

Non Small Cell Lung Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Weekly Paclitaxel/Carboplatin/Bevacizumab as First Line Therapy for Triple Negative Breast Cancer

Breast Cancer

Greece
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Withdrawn

Rituximab and Dexamethasone in Treating Patients With Recurrent or Refractory Indolent Non-Hodgkin's Lymphoma

Lymphoma

United States
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Withdrawn

Rituximab Plus Cyclophosphamide in Treating Patients With Indolent Stage III or Stage IV Non-Hodgkin's Lymphoma

Lymphoma

United States
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Withdrawn

Combination Chemotherapy Plus Interferon Alfa or Rituximab in Treating Patients With Stage III or Stage IV Lymphoma

Lymphoma

United States
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Withdrawn

Monoclonal Antibody Therapy or Biological Therapy in Treating Patients With Chronic Lymphocytic Leukemia or Multiple Myeloma in Remission After Chemotherapy

Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

United States
Hellenic Oncology Research Group
University Hospital of Crete

Terminated

Vinorelbine Metronomic Plus Bevacizumab as Salvage Therapy for Breast Cancer

Breast Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Epirubicin and Docetaxel Combination (ET) or Epirubicin Followed by Docetaxel (E/T) for Node Negative (N0) High Risk Breast Cancer Patients

Breast Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Postoperative Chemotherapy and Chemo-radiotherapy for Resected Gastric Cancer

Gastric Cancer

Greece
SOLTI Breast Cancer Research Group
Sysmex America, Inc.

Completed

Sentinel Lymph Node Total Tumoral Load as a Predictor of Non Sentinel Node Involvement in Early Breast Cancer (SOLO-1)

Breast Cancer

Spain
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Cisplatin/Vinorelbine/Bevacizumab Followed by Docetaxel/Gemcitabine/Bevacizumab Versus the Cisplatin/Docetaxel/Bevacizumab Combination in Locally Advanced or Metastatic NSCLC

Non Small Cell Lung Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Terminated

Gemcitabine Plus Erlotinib Versus Erlotinib Plus Gemcitabine Plus Oxaliplatin, in Pancreatic Cancer

Pancreatic Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Terminated

Randomized Phase II Study of Epirubicin vs Caelyx in Pretreated Metastatic Breast Cancer

Breast Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Terminated

Phase II Study of Avastin + Erbitux + Irinotecan as 2nd Line Treatment of Colorectal Cancer

Colorectal Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Irinotecan Plus Cisplatin vs Pemetrexed Plus Cisplatin as 2nd Line in NSCLC Stage IIIB/IV

Non Small Cell Lung Cancer

Greece
Hoag Memorial Hospital Presbyterian
Cancer Biotherapy Research Group

Completed

Isotretinoin Plus Interferon in Treating Patients With Recurrent Cancer

Cervical Cancer | Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Penile Cancer | Non-melanomatous Skin Cancer

United States
Asia Metabolic Surgery Research Group
E-DA Hospital

Unknown

Efficacy and Safety Study of Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) to Treat Type 2 Diabetes Mellitus (ADSMT-1)

Type 2 Diabetes Mellitus - Poor Control

Taiwan
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Phase III Study of Folfiri+Avastin Versus Xeliri+Avastin as 1st Line Treatment of CRC

Colorectal Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Erlotinib as 1st Line Treatment in NSCLC Stage IIIB/IV

Non Small Cell Lung Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Vinorelbine and Gemcitabine Versus Capecitabine in Pretreated Metastatic Breast Cancer

Breast Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Phase III Trial With Docetaxel Plus Epirubicine Versus Docetaxel Plus Capecitabine for Metastatic Breast Cancer

Breast Cancer

Greece
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Phase III Trial Comparing Sequential Administration of FE75C Followed by Docetaxel Versus Paclitaxel as Adjuvant Chemotherapy in Axillary Lymph Node (+) Breast Cancer

Breast Cancer

Greece
European Organisation for Research and Treatment...
Breast International Group; Menarini Group

Recruiting

Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) (TREAT ctDNA)

Stage IIB Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | Stage III Breast Cancer

Belgium, Italy, Ireland, France, Germany
NCIC Clinical Trials Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Institute... and other collaborators

Terminated

Observation or Radical Treatment in Patients With Prostate Cancer

Prostate Cancer

Canada
Spanish Breast Cancer Research Group
Novartis Pharmaceuticals; ETOP IBCSG Partners Foundation; Breast International...

Active, not recruiting

Trastuzumab + Alpelisib +/- Fulvestrant vs Trastuzumab + CT in Patients With PIK3CA Mutated Previously Treated HER2+ Advanced BrEasT Cancer (ALPHABET) (ALPHABET)

Advanced Breast Cancer

Spain, Netherlands, France, Italy, Austria, Switzerland
European Organisation for Research and Treatment...
Australasian Gastro-Intestinal Trials Group; Italian Sarcoma Group; Scandinavian...

Unknown

Imatinib Mesylate in Treating Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumor

Gastrointestinal Stromal Tumor
Theratechnologies
ICON Clinical Research; Excelsus Statistics Inc.; Health Psychology Research...

Recruiting

A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab (PROMISE-US)

HIV Infections | Multi-Antiviral Resistance

United States
LifeMark Health Research Group
LifeMark Health; Calgary Orthopaedic Research and Education Fund

Completed

A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery

Anterior Cruciate Ligament Reconstruction

Canada
Jordan Collaborating Cardiology Group
The Jordan Cardiovascular Research Group JoCVRG; Yarmouk University School...

Recruiting

Cardiovascular Patients With no Standard Modifiable Risk Factors (SMuRF-less-ME1)

Cardiovascular Risk Factors

Jordan
Gynecologic Oncology Group
National Cancer Institute (NCI); Medical Research Council; Southwest Oncology...

Completed

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States
Groupe Hospitalier Paris Saint Joseph
The Outcomerea Group for Intensive Care Research; the Regional Direction of... and other collaborators

Completed

a Multifaceted Program for Improving Quality of Care in ICU

Adverse Event | Intensive Care Units | Indicator

France

Clinical Trials Sponsored by Vanguard Research Group

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