Search clinical trials for: Adaptive trial

Total 42258 results

Boston Immune Technologies and Therapeutics

Not yet recruiting

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

Peripheral T-cell Lymphoma | NHL | Cutaneous T Cell Lymphoma
Opella Healthcare Group SAS, a Sanofi Company

Not yet recruiting

Bioavailability Study of Magne-B6 New Formulation

Healthy Volunteers
Washington University School of Medicine
Alzheimer's Association; Eisai Inc.

Not yet recruiting

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease (DIAN-TU)

Dementia | Alzheimer's Disease | Alzheimer's Disease, Familial

United States, Australia, United Kingdom
Chinese SLE Treatment And Research Group
Beijing Life oasis public service center

Not yet recruiting

A Study on the Prevention and Treatment of GIOP With Eldecalcitol (ELEGANT)

Rheumatoid Arthritis | Osteoporosis | Osteopenia

China
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Spain, Canada, Germany, Argentina, Belgium, Czechia, Greece, Israel, Austria, Brazil, Mexico, Netherlands, Romania, India, United Kingdom, Slovakia, Poland, Turkey, Puerto Rico, France, Denmark
Peking University

Not yet recruiting

Financial Incentives and Motivational Intervention to Improve Gastric Cancer Screening in China

Gastric Cancer
University of Bern
Swiss National Science Foundation; University of Zimbabwe

Not yet recruiting

The Friendship Bench Plus Trial (FB+)

Major Depressive Disorder | Severe Depressive Episode Without Psychotic Symptoms

Zimbabwe
University Health Network, Toronto

Not yet recruiting

Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following DRF Fixation (TRADR)

Distal Radius Fractures

Canada
Regeneron Pharmaceuticals

Not yet recruiting

Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC)

Cutaneous Squamous Cell Carcinoma
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy
Kantonsspital Winterthur KSW
Luzerner Kantonsspital

Not yet recruiting

Skin Cancer and Hyperthermia and Radiotherapy (SAHARA)

Basal Cell Carcinoma | Non-melanoma Skin Cancer | Squamous Cell Carcinoma Skin

Switzerland
Tufts Medical Center
University of California, Los Angeles; The Cleveland Clinic; Boston Medical Center and other collaborators

Not yet recruiting

Remote Tai Chi for Knee Osteoarthritis (TAICHIKNEE)

Knee Osteoarthritis

United States
AQTIS Medical B.V.

Not yet recruiting

A Prospective, Randomized, No-treatment Controlled, Evaluator-blinded Clinical Trial to Evaluate the Efficacy and Safety of Polycaprolactone Microspherical Injectable to Improve Forehead Contour

Forehead Contouring

China
University Hospital, Tours

Not yet recruiting

Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial- (PROTO-EHPAD)

Depression | Neurocognitive Disorders
McMaster University
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

A Trial of a Next Generation COVID-19 Vaccine Delivered by Inhaled Aerosol (AeroVax)

COVID-19 Infection

Canada
University Ghent
Research Foundation Flanders

Not yet recruiting

Effect and Cost-utility of of High Intensity vs. Low Intensity Speech Intervention in Children With Cleft Palate

Cleft Lip and Palate | Cleft Palate Children | Speech Therapy | Speech Disorders in Children
Montefiore Medical Center

Not yet recruiting

Antiemetic Fosaprepitant To Remedy Nausea and Vomiting (AFTR NV RCT)

Nausea | Vomiting | Nausea and Vomiting

United States
Cancer Research UK
UCB Biopharma SRL

Not yet recruiting

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

Uterine Cervical Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Neoplasms | Advanced Solid Tumours | Carcinoma, Renal Cell (Clear Cell Only) | Stomach Neoplasms...

United Kingdom
Universitaire Ziekenhuizen KU Leuven

Recruiting

Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial

Eosinophilic Esophagitis

Belgium
GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
Northwell Health

Recruiting

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Pain, Postoperative | Postoperative Pain, Acute

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne

Moderate to Severe Acne Vulgaris

China
Vastra Gotaland Region

Recruiting

Lifestyle Intervention With Physical Activity and Diet (LI-PAD)

Overweight

Sweden
Mayo Clinic

Recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
Regeneron Pharmaceuticals
Intellia Therapeutics

Not yet recruiting

A Trial to Learn if REGV131-LNP1265 is Safe and Works to Help the Body Make Clotting Factor in Pediatric, Adolescent and Adult Patients With Hemophilia B (BEYOND-9)

Hemophilia B
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
The Hong Kong Polytechnic University
Chinese University of Hong Kong; The University of New South Wales; Neuroscience...

Recruiting

The Effect of Combined Volitional and Reactive Step Training in Reducing Falls Risk in Older Fallers

Older Adults With a History of Falls

Hong Kong
JHSPH Center for Clinical Trials
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Multi-Center Clean Air Randomized Controlled Trial in COPD (Clean Air)

Chronic Obstructive Pulmonary Disease (COPD)

United States
University Hospitals Cleveland Medical Center

Not yet recruiting

eHealth for Breastfeeding Support - the HOTSPOT Trial

Breast Feeding

United States
Indian Council of Medical Research
King George's Medical University; Lady Hardinge Medical College; King Edward... and other collaborators

Not yet recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates (SAUNA)

Sepsis | Preterm Birth | Preterm Premature Rupture of Membrane | PROM, Preterm (Pregnancy) | Early-Onset Neonatal Sepsis

India
Bayer

Recruiting

A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Recruiting

A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy

Colorectal Neoplasia

United States
Vall d'Hebron Institute of Oncology

Recruiting

Status of HRD That Lead to a Benefit From Olaparib in Combination With Bevacizumab (STROBE Trial) (STROBE)

Ovarian Cancer

Spain
Etienne Xavier Keller

Recruiting

Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery (PENIS)

Erection; Incomplete

Switzerland
Mayo Clinic

Recruiting

Remote Cognitive Assessment Battery and Wearable Device Monitoring Platform While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

Malignant Brain Neoplasm

United States
Maastricht University Medical Center

Not yet recruiting

Accelerated Pacing in Patients Undergoing Pace-and-ablate Strategy With LBBAP: a Randomized Controlled Pilot Trial (PACE-AF)

Atrial Fibrillation | Pacemaker DDD | Paroxysmal Atrial Fibrillation | Persistent Atrial Fibrillation | Permanent Atrial Fibrillation
Brigham and Women's Hospital

Not yet recruiting

Time-limited Trials in the Emergency Department

Emergencies

United States
Amany Ahmed Eissa

Recruiting

The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients: Randomized Controlled Trial.

Erector Spinae Plane Block | Bariatric Surgery | Super Obese Patients

Egypt
Hospital Universitari de Bellvitge
Hospital Universitario Ramon y Cajal; Complejo Hospitalario de Navarra; University... and other collaborators

Not yet recruiting

EUS-Gallbladder vs CDS as First Line in MBDO- Palliative (CARPEGIEM Trial) (CARPEGIEM)

Biliary Tract Neoplasms | Malignant Biliary Obstruction | Pancreatic Cancer Non-resectable

Spain
Hospital Universitari de Bellvitge
Hospital Universitario Ramon y Cajal; Complejo Hospitalario de Navarra; University... and other collaborators

Not yet recruiting

EUS-guided Choledochoduodenostomy vs ERCP as First Line in Malignant Distal Obstruction in Resectable Disease (CARPEDIEM-1 Trial)

Biliary Tract Neoplasms | Pancreatic Cancer Resectable | Malignant Biliary Obstruction

Spain
Shanghai Juncell Therapeutics

Not yet recruiting

Engineering Tumor Infiltrating Lymphocytes Injection (GC203 TIL) for the Treatment of Advanced Malignant Solid Tumors (KUNLUN-001)

Breast Cancer | Gynecologic Cancer | Lung Cancer | Solid Tumor | Gastrointestinal Cancer
Amgen

Recruiting

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

Asthma

United States
Wolfson Medical Center

Not yet recruiting

The Impact of a Customized Informative Video Prior to Induction of Labor on Anxiety Relieve - a Randomized Controlled Trial

Induction of Labor Affected Fetus / Newborn
Tianjin Medical University Cancer Institute and...

Not yet recruiting

A Single Arm, Single Centered Phase II Trial on the Combination of Adebrelimab, Surufatinib and Irinotecan Liposome-based HAIC in Advanced iCC

Intrahepatic Cholangiocarcinoma

China
University of Exeter
China Scholarship Council; Ningbo University

Recruiting

The Benefits of a High-intensity Interval Training Intervention Delivered in a School Setting Among Adolescents

Healthy

United Kingdom
Hospital Universitari de Bellvitge
Hospital Universitario Ramon y Cajal; Complejo Hospitalario de Navarra; University... and other collaborators

Not yet recruiting

EUS-guided CDS vs ERCP as First Line in Malignant Distal Obstruction in Borderline Disease (CARPEDIEM-2 Trial)

Pancreatic Cancer | Biliary Tract Neoplasms | Malignant Biliary Obstruction

Spain
Maastricht University Medical Center
Diabetes Fonds

Recruiting

The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes (PYRAMID)

Type 2 Diabetes | Neuropathy, Diabetic | Nephropathy, Diabetic | Microvascular Function | Retinopathy, Diabetic

Netherlands
Hospital Universitario Marqués de Valdecilla

Recruiting

Effects of Topical Sesame Oil in the Prevention of Peripheral Venous Catheter Phlebitis: Clinical Trial.

Phlebitis

Spain

Search clinical trials for: Adaptive trial

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