Search clinical trials for: inadequately responsive

Total 884 results

Peking Union Medical College Hospital

Completed

Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness

Shock | Hypotension | Fluid Responsiveness | Fluid Challenge

China
Mayo Clinic

Completed

Proton Pump Inhibitor (PPI) Responsive Eosinophilic Esophagitis EoE: Gastroesophageal Reflux Disease (GERD) or Eosinophilic Esophagitis (EoE)?

Erosive Esophagitis

United States
South West Sydney Local Health District

Completed

Fluid Responsiveness After CArdiac Surgery Study (FRACAS)

Critically Ill | Hypovolemia

Australia
Erasme University Hospital

Completed

Implementation of Computer-Assisted Intraoperative Goal-Directed Fluid Therapy

Major Abdominal Surgery

Belgium
National Taiwan University Hospital

Unknown

Preoperative Goal-directed Fluid Therapy and Physiological Changes Following One-lung Ventilation

Therapy Adverse Effect
Novo Nordisk A/S

Completed

Comparison of the Efficacy and Safety of Two Intensification Strategies in Subjects With Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin (BEGIN™)

Diabetes Mellitus, Type 2 | Diabetes

United States, Spain, Denmark, Austria, Belgium, Serbia, Germany, Canada, France, Finland, Norway, Czech Republic
Novo Nordisk A/S

Completed

A Trial Comparing the Glycaemic Control of Levemir® Administered Once Daily According to Two Insulin Detemir Titration Algorithms After 20 Weeks in Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin Treatment With or Without Other Anti-diabetic Drugs (OADs)

Diabetes Mellitus, Type 2 | Diabetes

Korea, Republic of
University Hospital, Lille

Completed

Respiratory Variations for Predicting Fluid Responsiveness (ReVaPreF)

Sepsis | Circulatory Failure | Respiratory Physiological Phenomena

France
University Hospital, Lille

Terminated

Accuracy of Pulse Pressure Variations Measured by a Non Invasive Digital Device to Predict Fluid Responsiveness

Systemic Inflammatory Response Syndrome | Mechanical Ventilation | Circulatory Failure

France
University Hospital, Lille

Completed

Respiratory Variations For Predicting Fluid Responsiveness 2 (ReVaPreF2)

Sepsis | Circulatory Failure | Respiratory Physiological Phenomena

France
Novartis

Completed

Vildagliptin 100 mg Once Daily vs. Placebo as add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Diabetes Mellitus, Type 2

Germany
Novartis Pharmaceuticals

Completed

Vildagliptin 50 mg Twice Daily in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin

Type 2 Diabetes Mellitus

Egypt
Novo Nordisk A/S

Completed

Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin (SIT2MIX)

Diabetes Mellitus, Type 2 | Diabetes

Korea, Republic of, India, Malaysia, Turkey, Argentina, Greece, Australia, Portugal, Thailand, Brazil
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone

Diabetes Mellitus Type 2

United States, Mexico, Argentina
Novo Nordisk A/S

Terminated

Comparison of Efficacy and Safety of Repaglinide Combined With Insulin NPH Versus Biphasic Human Insulin 30 Alone in Inadequately Controlled Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Greece
Mayo Clinic
University of Manchester

Completed

Cough Reflex Sensitivity and Bronchial Hyper-responsiveness

Gastroesophageal Reflux Disease | Chronic Cough | Broncho-hyperreactivity

United States
University of Aarhus
Philips Healthcare

Completed

Fluid Responsiveness Prediction Using Extra Systoles

Fluid Responsiveness

Denmark
Novo Nordisk A/S

Completed

A Trial Investigating the Efficacy and Safety of Flexible vs. Fixed Dosing and Simple vs. Stepwise Titration With Once Daily (OD) Insulin Degludec in Inadequately Treated Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Lithuanian University of Health Sciences

Completed

Focused Assessed Echocardiography to Predict Fluid Responsiveness (fluidres)

Surgery | Hypotension | Hypovolemia
Novartis

Completed

A Clinical Study to Compare Combination of Aliskiren+ HCTZ to Irbesartan+ HCTZ or Amlodipine+ HCTZ or HCTZ Alone in Obese Hypertensive Not Responsive to HCTZ 25 mg

Hypertension

United States, Germany
AstraZeneca

Completed

Responsiveness of Lower Airways in Adult Patients (18-60 Years) With Stable Asthma After Treatment With Ciclesonide and Fluticasone Propionate (BY9010/NL-101)

Asthma

Netherlands
Novo Nordisk A/S

Completed

Efficacy and Safety of Insulin Detemir in Type 2 Diabetes Inadequately Controlled on OHA Therapy Alone

Diabetes Mellitus, Type 2 | Diabetes

Japan
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes and Inadequately Controlled Hypertension on an Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker

Type 2 Diabetes

Mexico, Russian Federation, Spain, United States, Canada, Puerto Rico, Hungary, Peru, Romania, Poland, Germany, Czech Republic, India, Colombia, Denmark, Finland
Novo Nordisk A/S

Completed

Effect of Liraglutide on the Beta-cell Responsiveness in Subjects With Type 2 Diabetes Compared to a Healthy Control Group

Diabetes Mellitus, Type 2 | Diabetes

United States
AstraZeneca

Completed

Efficacy and Safety Study of Benralizumab in Adults and Adolescents Inadequately Controlled on Inhaled Corticosteroid Plus Long-acting β2 Agonist

Asthma

United States, Poland, Germany, Sweden, Philippines, Romania, Ukraine, Argentina, Canada, Chile, Japan
Military Hospital of Tunis

Unknown

Analysis of Respiratory Variations of the Right Internal Jugular Vein as a Predictor of Fluid Responsiveness During Mechanical Ventilation

Ultrasonography | Jugular Veins
Novo Nordisk A/S

Completed

Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs

Diabetes Mellitus, Type 2 | Diabetes

Morocco, Tunisia, Algeria, South Africa, Egypt
Pfizer

Terminated

POC Study in Partially Responsive Generalized Anxiety Disorder

Generalized Anxiety Disorder

United States
AstraZeneca
Bristol-Myers Squibb

Completed

A Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes With Inadequately Controlled Hypertension on an ACEI or ARB and an Additional Antihypertensive Medication

Type 2 Diabetes

Australia, United States, Canada, Mexico, Puerto Rico, Germany, Hungary, Ireland, Poland, Romania, Denmark, Czech Republic, India, Colombia, Finland, United Kingdom
Hopital Louis Pradel

Completed

Fluid Responsiveness Evaluation by AbdomiNal Compression in Kids Based on the STARLING Concept (FRANCK)

Circulatory Failure

France
University of North Carolina, Chapel Hill

Completed

Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn

Gastroesophageal Reflux Disease | Heartburn

United States
Massachusetts General Hospital
rEVO Biologics

Completed

Understanding "Heparin Resistance" in Cardiac Surgery

Cardiopulmonary Bypass | Altered Heparin Response

United States
Genentech, Inc.

Completed

A Study of Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Inadequately Controlled on Inhaled Corticosteroids (MILLY)

Asthma
Janssen Research & Development, LLC

Completed

Study to Evaluate the Effects of Domperidone on Cardiac Repolarization in Chinese Healthy Participants

Healthy

China
Novartis

Completed

Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy

Type 2 Diabetes Mellitus

China
Triemli Hospital

Completed

Assessment of Fluid Responsiveness in Patients After Cardiac Surgery (POP)

Hemodynamics | Patient Monitoring

Switzerland
Hoffmann-La Roche

Completed

A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin.

Diabetes Mellitus Type 2

United States, France, Switzerland, Germany, South Africa, Korea, Republic of, Puerto Rico, Canada, Taiwan, Spain, Poland, Slovakia, Thailand, Mexico, Turkey, Australia, Greece, Norway, Sweden, Peru, Romania, Argentina, United Kingdom
Hopital Foch

Completed

Accuracy of Pulse Pressure Variation and of Pleth Variability Index to Predict the Response to a Fluid Challenge (Nexfin2)

Fluid Responsiveness

France
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

Diabetes Mellitus Type 2

Korea, Republic of, China
Genentech, Inc.

Completed

A Study of MEMP1972A in Patients With Allergic Asthma Inadequately Controlled on Inhaled Steroids And A Second Controller (COSTA)

Asthma

Belgium, Germany, United States, New Zealand, Canada, Poland, Bulgaria, Romania, Russian Federation, Hungary, Ukraine, Peru, Argentina, Mexico
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Sulfonylurea Alone or Sulfonylurea Plus Metformin Therapy

Diabetes Mellitus Type 2

Colombia, United States, Mexico, Guatemala, Argentina
Hoffmann-La Roche

Withdrawn

A Study of RO6811135 in Patients With Type 2 Diabetes Who Are Inadequately Controlled With Metformin

Diabetes Mellitus Type 2
Hoffmann-La Roche

Completed

A Study of Taspoglutide Versus Exenatide for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin, Thiazolidinedione or a Combination of Both.

Diabetes Mellitus Type 2

Sweden, United States, Mexico, South Africa, Russian Federation, France, Spain, Switzerland, Canada, Finland, New Zealand, Korea, Republic of, Thailand, Israel, Germany, Peru, Australia, Denmark, Italy, Ukraine, Greece, Puerto Rico, Guatemal... and more
Hoffmann-La Roche

Completed

A Study of Taspoglutide in Patients With Inadequately Controlled Diabetes Mellitus Type 2 and Cardiovascular Disease

Diabetes Mellitus Type 2

Spain, United States, Estonia, Mexico, South Africa, Taiwan, Russian Federation, Canada, Slovakia, United Kingdom, Malaysia, Thailand, Australia, Hungary, Bulgaria, Brazil, Germany, Lithuania, Denmark, Romania, Ukraine, Poland, India, Israe... and more
Hoffmann-La Roche

Terminated

A Study to Compare Taspoglutide and Insulin Glargine in Insulin-Naïve Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin and Sulfonylurea Combination Therapy

Diabetes Mellitus Type 2

China, Hong Kong, Korea, Republic of, Philippines, Taiwan, Malaysia, Thailand
Hoffmann-La Roche

Completed

A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin

Diabetes Mellitus Type 2

Germany
ETOP IBCSG Partners Foundation
National Cancer Institute (NCI); Breast International Group

Terminated

Premenopausal Endocrine Responsive Chemotherapy Trial (PERCHE)

Breast Cancer

Switzerland, Italy, Hungary
University of Saskatchewan

Completed

Mannitol (Aridol) and Methacholine (Provocholine) Responsiveness

Asthma

Canada
Abbott Medical Devices

Completed

ABSORB FIRST is a Registry Designed to Evaluate the Safety and Performance of Absorb Bioresorbable Vascular Scaffold (Absorb BVS) Used in Real-world Patients.

Coronary Artery Disease | Coronary Disease | Coronary Occlusion | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Coronary Artery Stenosis | Coronary Artery Restenosis

Belgium
Miroslaw Szura
Jagiellonian University; Specialist Diagnostic and Therapeutic Center MEDICINA

Unknown

Advanced Endoscopic Imaging in Colonoscopy (AEI)

Neoplasms | Polyps

Poland

3

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