Clinical Trials Sponsored by Byron Lam

Total 8560 results

Hoffmann-La Roche

Completed

A Study of Tocilizumab Added to DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to DMARDs.

Rheumatoid Arthritis

Russian Federation
Hoffmann-La Roche

Completed

PHOENIX Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) and COPEGUS (Ribavirin) Administered After Liver Transplantation for Hepatitis C.

Hepatitis C, Chronic

United States
Hoffmann-La Roche

Completed

A Non-Interventional Study of Treatment Pattern and Clinical Outcomes in Chinese Participants With Gastric Cancer (EVIDENCE)

Gastric Cancer

China
Hoffmann-La Roche

Completed

A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy

Post-Operative Nausea and Vomiting

United States
Hoffmann-La Roche

Terminated

A Study of Rituximab in Combination With Fludarabine and Cyclophosphamide in Participants With Chronic Lymphocytic Leukemia and Favorable Somatic Status

Lymphocytic Leukemia, Chronic

Russian Federation
Hoffmann-La Roche

Completed

A Study of Mircera in Anemic Patients With Multiple Myeloma

Anemia

Poland, Czechia
Hoffmann-La Roche

Completed

A Phase IV Study to Evaluate the Effect of Subcutaneous (SC) Tocilizumab Administered to Participants With Rheumatoid Arthritis (RA) Assessed Using Disease Activity Score (DAS28)

Rheumatoid Arthritis

Slovakia
Hoffmann-La Roche

Completed

Observational Study of Vismodegib (Erivedge) in Patients Treated in Argentina

Basal Cell Carcinoma
Hoffmann-La Roche

Completed

A Study Examining Maintenance Bevacizumab (Avastin®) Monotherapy in Participants With Advanced Lung Adenocarcinoma

Lung Adenocarcinoma

Hungary
Hoffmann-La Roche

Completed

A Study of Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic Acid (mRNA) Antagonist (RO7070179), to Demonstrate Proof-of-mechanism in Adult Participants With Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular

United States
Hoffmann-La Roche

Completed

A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin's Lymphoma Grades 1, 2 or 3a

Diffuse Large B-Cell Lymphoma, Non-Hodgkin's Lymphoma

Hong Kong, Germany, Philippines, Taiwan, Turkey, Canada, Australia, Austria, New Zealand, Thailand, Hungary, Italy, Korea, Republic of, Romania, Netherlands, Brazil, Indonesia, Croatia, Egypt, Portugal, Sweden, Colombia, Argentina, De... and more
Hoffmann-La Roche

Completed

A Study to Compare Subcutaneous (SC) Versus Intravenous (IV) Administration of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer

Breast Cancer

Canada, Germany, Korea, Republic of, Panama, Spain, Turkey, Brazil, Colombia, France, Hungary, Russian Federation, Taiwan, Thailand, Czechia, Italy, Estonia, Peru, South Africa, Sweden, Poland, Israel, Hong Kong, Mexico, Guatemala, Arge... and more
Hoffmann-La Roche

Completed

A Two Part Study of RO6870810. Dose-Escalation Study in Participants With Advanced Solid Tumors and Expansion Study in Participants With Selected Malignancies

Solid Tumors, Advanced Solid Tumors

United States
Hoffmann-La Roche

Completed

A Study of Mircera in Anemic Patients With Chronic Kidney Disease Not Yet on Dialysis.

Anemia

United States, Canada, United Kingdom, Mexico, Poland
Hoffmann-La Roche

Completed

A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX

Rheumatoid Arthritis

United States
Hoffmann-La Roche

Completed

A Study of Subcutaneously Administered Tocilizumab in Participants With Systemic Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

United States, Canada, United Kingdom, Brazil, Argentina, Germany, Italy, Russian Federation, Spain, Mexico, Australia, France
Hoffmann-La Roche

Completed

Observational Study to Evaluate Disease Course and Outcomes in Patients Treated With Esbriet (Pirfenidone) for Idiopathic Pulmonary Fibrosis (IPF) in Canada

Idiopathic Pulmonary Fibrosis

Canada
Hoffmann-La Roche

Completed

A Study to Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on Ipatasertib

Healthy Volunteers

United States
Hoffmann-La Roche

Completed

A Non-Interventional Safety Study of Balsamic Bactrim

Bronchitis

Peru
Hoffmann-La Roche

Completed

Evaluation of [18F]RO6958948 as Tracer for Positron Emission Tomography (PET) Imaging of Tau Burden in Alzheimer's Disease Participants

Alzheimer's Disease

United States
Hoffmann-La Roche

Completed

A Study of Oral Vismodegib in Combination With Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis (ISLAND2)

Idiopathic Pulmonary Fibrosis

United States, Germany
Hoffmann-La Roche

Withdrawn

A Study Exmining the Effect of Multiple Doses of Bitopertin on the Single Dose Pharmacokinetics of Midazolam in Healthy Volunteers.

Healthy Volunteer
Hoffmann-La Roche

Completed

A Study Examining Long Response in Lung Cancer Patients Treated With Tarceva (Erlotinib)

Non-Small Cell Lung Cancer

Italy
Hoffmann-La Roche

Completed

A Study of Subcutaneous Versus Intravenous MabThera/Rituxan (Rituximab) in Combination With CHOP Chemotherapy in Patients With Previously Untreated CD20-Positive Diffuse Large B-Cell Lymphoma

Lymphoma, Large B-Cell, Diffuse

Italy, Belgium, Canada, Finland, Ireland, Netherlands, Peru, Spain, United Kingdom, Venezuela, Russian Federation, Brazil, France, Poland, Israel, South Africa, Thailand, Bulgaria, Colombia, Greece, Turkey, Argentina, Saudi Arabia, Uk... and more
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Combination With Interferon Alpha-2a as First-Line Treatment in Patients With Advanced and/or Metastatic Renal Cell Carcinoma

Renal Cell Cancer

India
Hoffmann-La Roche

Completed

APPROACH Study: Quality of Life and Outcomes Assessment in Participants With Chronic Hepatitis C (CHC) Treated With Pegylated Interferon (PEG-IFN) Alfa-2a and Ribavirin

Hepatitis C, Chronic

Canada
Hoffmann-La Roche

Completed

An Observational Study of the Safety of Herceptin Given Subcutaneously in Patients With Early HER2-positive Breast Cancer

Breast Cancer

France
Hoffmann-La Roche

Completed

Placebo-Controlled, Single and Multiple Ascending Subcutaneous Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986089 in Healthy Adult Subjects

Healthy Adults

United States
Hoffmann-La Roche

Completed

A Study Evaluating the Effects of Lebrikizumab on Airway Eosinophilic Inflammation in Participants With Uncontrolled Asthma

Asthma

United States, Canada, United Kingdom, Sweden, France, Ireland
Hoffmann-La Roche

Completed

An Observational Study in Participants With Chronic Hepatitis B (CHB) Receiving Therapy With Peginterferon Alfa-2a 40 Kilodaltons (kD) (PEGASYS) - The PRO B Study

Hepatitis B, Chronic

Serbia
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Combination With Paclitaxel in First-Line Treatment in Patients With HER2-Negative Metastatic Breast Cancer

Breast Cancer

Croatia
Hoffmann-La Roche

Completed

A Study of MabThera/Rituxan (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis and Inadequate Response to DMARD Therapy

Rheumatoid Arthritis

Serbia
Hoffmann-La Roche

Withdrawn

A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease.

Pain | Neoplasm Metastasis | Bone Neoplasm

Greece
Hoffmann-La Roche

Terminated

A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain

Pain | Neoplasm Metastasis | Bone Neoplasm

United States, Italy, Chile, Russian Federation, Hungary, United Kingdom, Poland, Guatemala, Germany, Mexico, Puerto Rico, Greece, Australia, Switzerland, Argentina, Panama
Hoffmann-La Roche

Completed

A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Rheumatoid Arthritis

Tunisia
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs or Anti-TNF

Rheumatoid Arthritis

Saudi Arabia
Hoffmann-La Roche

Completed

A Study of MabThera (Rituximab) in Participants With Rheumatoid Arthritis Who Have Had an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARD) and/or Anti-Tumor Necrosis Factor (Anti-TNF) Therapy.

Rheumatoid Arthritis

Israel
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Philippines
Hoffmann-La Roche

Completed

Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Participants With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Non-Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) and/or Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Rheumatoid Arthritis

India
Hoffmann-La Roche

Completed

An Observational Study to Describe in Routine Clinical Practice the Treatment Patterns of Usage of Biological DMARDs in RA Patients.

Rheumatoid Arthritis

China
Hoffmann-La Roche

Completed

An Observational Study of Tocilizumab (Actemra) in Participants With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Peru
Hoffmann-La Roche

Completed

A Study of Rituximab in Combination With Chemotherapy in Relapsed/Refractory Follicular Lymphoma (REFLECT 2)

Lymphoma, Follicular

Serbia
Hoffmann-La Roche

Completed

A Study on The Safety of Administering Rituximab at A More Rapid Rate in Patients With Rheumatoid Arthritis (RATE-RA)

Rheumatoid Arthritis

United States
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Combination With DMARD Therapy in Patients With Active Rheumatoid Arthritis.

Rheumatoid Arthritis

China
Hoffmann-La Roche

Completed

A Study of RO5185426 in Previously Treated Melanoma Patients With Brain Metastases

Malignant Melanoma

Switzerland
Hoffmann-La Roche

Completed

A Study of the Effect of Tocilizumab on Markers of Atherogenic Risk in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Canada, Puerto Rico, United Kingdom
Hoffmann-La Roche

Completed

A Study of Mircera (C.E.R.A.) in Patients With Pre-Dialysis Chronic Renal Anemia

Anemia

Egypt
Hoffmann-La Roche

Completed

A Study of Oral Valcyte (Valganciclovir) in Pediatric Kidney Transplant Recipients

Kidney Transplantation, Cytomegalovirus Infections

Spain, Mexico, United Kingdom, United States, Australia, Brazil, France, Germany, Sweden
Hoffmann-La Roche

Completed

A Study to Evaluate Efficacy of Tocilizumab Administered as Monotherapy or in Combination With Methotrexate and/or Other Disease Modifying Antirheumatic Drugs (DMARDs) in Rheumatoid Arthritis (RA) Participants

Rheumatoid Arthritis

Italy
Hoffmann-La Roche

Completed

An Observational Study of BRAF Inhibitors Effectiveness in Patients With Newly Diagnosed Metastatic Melanoma

Malignant Melanoma

Italy

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