Search clinical trials for: Controlled Human Infection Model

Total 84764 results

National Center for Research Resources (NCRR)
University of Maryland

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Copolymer 1 for Relapsing-Remitting Multiple Sclerosis

Multiple Sclerosis
Eunice Kennedy Shriver National Institute of Child...

Completed

Evaluating Muscle Function After Ankle Surgery

Muscle Weakness | Muscle Atrophy | Fractures

United States
Royal Brompton & Harefield NHS Foundation Trust
CORDA, The Heart Charity; Apotex Inc.; The Cooley's Anemia Foundation,; The UK...

Unknown

Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major

Beta-Thalassemia

Italy
Shady Grove Fertility Reproductive Science Center

Completed

Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection

Infertility | Infertility, Male

United States
Amgen

Completed

Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Merck Sharp & Dohme LLC

Completed

A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 Mg q 8 h Versus 1,200 Mg q 12 h in Combination With Zidovudine and 3TC

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Treadmill Training With Body Weight Support in Patients With Spinal Cord Injury

Spinal Cord Injury

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Preventing Osteoporosis in Adolescent Girls

Osteoporosis

United States
Wentworth Area Health Services
Abbott

Unknown

Levosimendan Versus Dobutamine in Shock Patients

Septic Shock | Cardiogenic Shock

Australia
Eunice Kennedy Shriver National Institute of Child...

Unknown

Preventing Learning Problems in Young Children: A Public Health and Physician-Based Outreach

Developmental Disabilities | Language Development Disorders

United States
Daiichi Pharmaceuticals

Completed

A Study of Tecogalan Sodium

HIV Infections | Sarcoma, Kaposi

United States
Merck Sharp & Dohme LLC

Completed

The Safety and Effectiveness of Indinavir Sulfate Plus Efavirenz

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Study of Capravirine Plus VIRACEPT Plus Two Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected Patients Who Failed Previous Anti-HIV Treatments

HIV Infections

United States
Walter Reed Army Institute of Research (WRAIR)

Unknown

HIV Candidate Vaccine, ALVAC-HIV-1, Administration in HIV-Negative Adults

HIV Infections | HIV Seronegativity

United States
VA Medical Center-Gainesville

Completed

Diethylhomospermine (DEHSPM) for Refractory AIDS-Related Diarrhea

HIV Infections | Diarrhea

United States
Astra USA

Completed

Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease

Gastrointestinal Diseases | HIV Infections

United States
OXO Chemie

Completed

A Study to Evaluate the Safety and Effectiveness of WF10 Given to Patients With Late-Stage HIV Disease

HIV Infections

Canada, United States
Hoffmann-La Roche

Completed

Dideoxycytidine ( Ro 24-2027 ). A Treatment Protocol for the Use of Dideoxycytidine ( ddC ) in Patients With AIDS or Advanced ARC Who Cannot Be Maintained on Zidovudine ( AZT ) Therapy.

HIV Infections

United States
Glaxo Wellcome

Completed

A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Who Are Intolerant of Trimethoprim / Sulfamethoxazole

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Hoffmann-La Roche

Completed

Ganciclovir: Compassionate Use in Patients With Serious or Life-Threatening Cytomegalovirus Infections

HIV Infections | Cytomegalovirus Infections

United States
Agouron Pharmaceuticals

Suspended

Safety and Effectiveness of a New Anti-HIV Drug (AG1549) in Combination With Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States, Dominican Republic
National Center for Research Resources (NCRR)

Completed

NNC 90-1170 Mechanism of Action: A Double-Blind, Randomized, Single-Center, Placebo-Controlled, Crossover Study to Examine Beta-Cell Responsiveness to Graded Glucose Infusion in Subjects With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
Pfizer

Completed

Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis

HIV Infections | Meningitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Trial To Evaluate the Safety and Immunogenicity of the UBI HIV-1MN PND Peptide Immunogen, Given by IM Injection, in Combination With the UBI Microparticulate Monovalent HIV-1 MN Branched Peptide Given Orally, in HIV-1 Uninfected Volunteers.

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study of L-735,524 in HIV-Positive Children and Adolescents

HIV Infections

United States
Hoffmann-La Roche

Completed

A Multiple Dose Crossover Pharmacokinetics Study to Evaluate the Effects of Food on the Absorption of Oral Ganciclovir

HIV Infections | Cytomegalovirus Infections

United States
Hoffmann-La Roche

Completed

A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Eunice Kennedy Shriver National Institute of Child...
Yale University

Terminated

Longitudinal and Biological Study of Childhood Disintegrative Disorder

Autism | Pervasive Child Development Disorders

United States
Amgen

Completed

The Effects of r-metHuIFN-Gamma on the Lungs of Patients With AIDS

HIV Infections

United States
Roche Global Development

Completed

A Study of Two Forms of Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
National Institute of Allergy and Infectious Diseases...

Completed

The Effects of Treatment for Mycobacterium Avium Complex (MAC) on the Cells of HIV-Infected Patients

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Hoffmann-La Roche

Completed

A Study of Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
University of Pittsburgh

Completed

The Effects of AZT and Ibuprofen on HIV-Infected Patients With Hemophilia

HIV Infections | Hemophilia A

United States
University of Miami

Completed

A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection

HIV Infections | Leukoencephalopathy, Progressive Multifocal

United States
Hoffmann-La Roche

Completed

A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine

HIV Infections | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Multicenter Study of Nontuberculous Mycobacteria in Cystic Fibrosis Patients

Cystic Fibrosis | Atypical Mycobacterium Infection
Glaxo Wellcome

Unknown

Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs

HIV Infections

United States
Gilead Sciences

Completed

A Compassionate Use Study of Tenofovir Disoproxil Fumarate as Treatment for HIV Infection

HIV Infections

United States
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS

HIV Infections | Meningitis, Cryptococcal

United States
Hoffmann-La Roche

Completed

An Open-Label Safety Program for the Use of Zalcitabine (Dideoxycytidine; ddC) in Pediatric Patients With Symptomatic HIV Infection Who Have Failed or Are Intolerant to AZT Monotherapy, or Who Have Completed Other ddC Protocols, or Are Ineligible for Other Ongoing Clinical Studies

HIV Infections

United States
Agouron Pharmaceuticals

Unknown

Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)

HIV Infections

United States
Glaxo Wellcome

Completed

An Oral Dose-Ranging Finding Study in Patients With HIV Disease, CDC Classification Groups IIB, III, and IV-C2

HIV Infections

United States
Gilead Sciences

Completed

A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient

HIV Infections

United States, Puerto Rico
National Institute of Environmental Health Sciences...

Completed

Geographic Modeling of Traffic and Asthma Rates

Asthma
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and Children

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Preventing Problem Behavior Among Middle School Students

Health Promotion | Substance Use Disorders
Glaxo Wellcome

Completed

An Open-Label, Uncontrolled Clinical Trial of Oral 566C80 for the Treatment of Patients With Severe PCP Who Are Intolerant and/or Unresponsive to Therapy With Trimethoprim/Sulfamethoxazole and Parenteral Pentamidine

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Glaxo Wellcome

Completed

A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 in HIV-Infected Patients

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination Therapy

HIV Infections

United States, Puerto Rico

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