Search clinical trials for: DPP-4 inhibitors

Total 68877 results

University Hospital, Gentofte, Copenhagen

Completed

GA 6: The Blood Glucose-lowering Effect of Glucose-dependent Insulinotropic Polypeptide

Type2 Diabetes

Denmark
Sierra Oncology, Inc.

Completed

Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, Canada, Australia
Neurim Pharmaceuticals Ltd.

Completed

Sleep Inducing And Maintaining Efficacy Of Circadin In Elderly Insomniacs (Neu I)

Primary Insomnia

France
Sierra Oncology, Inc.

Completed

Safety Study Evaluating Twice-Daily Administration of Momelotinib in Primary Myelofibrosis or Post-Polycythemia Vera or Post-Essential Thrombocythemia Myelofibrosis

Primary Myelofibrosis | Post-Polycythemia Vera | Post-Essential Thrombocythemia Myelofibrosis

United States, Canada
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors and Risk of Cardiovascular Events

Myocardial Infarction | Heart Failure | Ischemic Stroke | Type2 Diabetes | Cardiovascular Death | All-Cause Mortality

Canada
M.D. Anderson Cancer Center
GlaxoSmithKline

Not yet recruiting

A Phase I/II Study of Gilteritinib and Momelotinib for Patients With Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia

Myeloid Leukemia

United States
Lovoria Williams
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Enhanced DPP-GLB to Promote Weight Loss Among Nonresponders in a Community-Based Lifestyle Intervention.

Diabetes

United States
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Unknown

Intact Liver Innervation and Glucose and Glucagon-like Peptide-1 (GLP-1) Induced Insulin Secretion

Liver Transplantation

Denmark
GlaxoSmithKline

Active, not recruiting

Extended Access of Momelotinib in Adults With Myelofibrosis

Neoplasms | Primary Myelofibrosis (PMF) | Post-polycythemia Vera Myelofibrosis (Post-PV MF) | Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)

United States, Hungary, Israel, Spain, Taiwan, France, Australia, Germany, Belgium, Canada, Singapore, Korea, Republic of, United Kingdom, Denmark, Austria, Romania, Italy, Bulgaria, Poland, Netherlands
GlaxoSmithKline

No longer available

Managed Access Program for Momelotinib in Myelofibrosis

Primary Myelofibrosis | Myelofibrosis
Sierra Oncology, Inc.

Terminated

Safety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential Thrombocythemia

Polycythemia Vera | Essential Thrombocythemia

United States, France, Germany, Canada, Australia
LG Chem

Not yet recruiting

Food-effect Bioavailability of Gemigliptin and Dapagliflozin 50/10 mg

Healthy Volunteers
Sierra Oncology LLC - a GSK company

Completed

Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, France, Canada, Germany, Australia
Calliditas Therapeutics AB
Eurofins Optimed; York Bioanalytical Solution

Completed

Comparison of the Relative Oral Bioavailability of GKT137831 Formulated in Capsules or in Tablets

Phase 1

France
Sierra Oncology LLC - a GSK company

Completed

Momelotinib in Transfusion-Dependent Adults With Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)

Primary Myelofibrosis (PMF) | Post-polycythemia Vera (Post-PV) Myelofibrosis | Postessential Thrombocythemia (Post-ET) Myelofibrosis

United States, Canada
University of California, Davis
National Institute of Mental Health (NIMH); Washington University School of... and other collaborators

Enrolling by invitation

California Collaborative Network to Promote Data Driven Care and Improve Outcomes in Early Psychosis (EPI-CAL)

First Episode Psychosis (FEP)

United States
Sanofi

Completed

A PK Comparability Study of Two Different Amlitelimab Drug Products in Healthy Participants

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Sierra Oncology, Inc.

Completed

Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis (Simplify 1)

Primary Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-Essential Thrombocythemia Myelofibrosis

United States, France, Germany, Spain, Israel, Bulgaria, Romania, Japan, Taiwan, Korea, Republic of, Australia, Belgium, Canada, Netherlands, Singapore, Poland, Hungary, Denmark, Sweden, United Kingdom, Czechia, Austria
The Catholic University of Korea

Completed

DPP4 Inhibitor and Coronary Atherosclerosis in Patients Receiving Insulin Therapy

Diabetes Mellitus

Korea, Republic of
University of Washington
National Institute of Mental Health (NIMH)

Completed

Mobile Mental Health Apps for Suicide Prevention

Depression | Anxiety | Emotional Regulation

United States
Assiut University

Unknown

Assessment of Early Outcomes of Roflumilast in Patients With Non Cystic Fibrosis Bronchiectasis

Bronchiectasis
The University of Texas Medical Branch, Galveston

Withdrawn

Healthy Hearts: Leveraging the Diabetes Prevention Program to Decrease Health Disparities in Women of Reproductive Age (HH)

Hypertension | Prediabetic State | Overweight or Obesity | Gestational Weight Gain
Spectrum Health Hospitals
Helen DeVos Children's Hospital

Completed

Psychological Effects of Bone Marrow Transplants in Children

Psychological

United States
Astellas Pharma Inc

Completed

A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Japan
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs

Hyperglycemia | Obesity | Overweight | Weight Loss | PreDiabetes | Prediabetic State | Impaired Glucose Tolerance | Glucose, High Blood | Lifestyle, Healthy | Lifestyle Risk Reduction | Lifestyle, Sedentary

United States
Emory University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Oral Anti Diabetic Agents in the Hospital

Diabetes Mellitus

United States
Albert Einstein College of Medicine
New York Presbyterian Hospital; Chinese American Independent Practice Association... and other collaborators

Completed

Chinese Diabetes Prevention Program (Chinese DPP)

Prediabetes

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Mobilizing Doulas to Empower Black Women in Post-partum Diabetes Prevention

Type2 Diabetes | Gestational Diabetes

United States
Ganzhou Hemay Pharmaceutical Co., Ltd

Recruiting

A Study of Efficacy and Safety of Hemay005 Tablets in Patients With Behçet's Disease

Behçet's Disease

China
Tianjin Hemay Pharmaceutical Co., Ltd

Terminated

A Study to Evaluate the Efficacy and Safety of Hemay005 in the Treatment of Behçet Disease

Behçet Disease

China
Second Xiangya Hospital of Central South University
The First Affiliated Hospital with Nanjing Medical University; Beijing Hospital and other collaborators

Completed

Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes

Diabetes Mellitus, Type 1

China
Sierra Oncology, Inc.

Terminated

Efficacy and Safety of Momelotinib Combined With Trametinib in Adults With Metastatic KRAS-mutated Non-Small Cell Lung Cancer (NSCLC) Who Have Failed Platinum-Based Chemotherapy Preceded by a Dose-finding Lead-in Phase

Relapsed Metastatic KRAS-Mutated Non-Small Cell Lung Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Prognostic Stage IIIC Breast Cancer AJCC v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally... and other conditions

United States
Linkoeping University

Completed

Cognitive Behavioral Therapy Treatment of Depression With Smartphone Support

Depression

Sweden
Sierra Oncology, Inc.

Terminated

Momelotinib Combined With Capecitabine and Oxaliplatin in Adults With Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma

Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma

United States
University of Missouri, Kansas City
Children's Mercy Hospital Kansas City; University of Massachusetts, Amherst; University... and other collaborators

Recruiting

Social Determinants and a Diabetes Prevention Program Tailored for African Americans (FIT4ALL)

PreDiabetes | Overweight and Obesity

United States
Eli Lilly and Company

Completed

A Study Comparing Insulin Peglispro With Insulin Glargine as Basal Insulin Treatment

Type 2 Diabetes Mellitus

Japan, Taiwan, Korea, Republic of
G1 Therapeutics, Inc.

Completed

Safety, Pharmacokinetic and Pharmacodynamic Study of the CDK 4/6 Inhibitor G1T28-1

Healthy Volunteers

Netherlands
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Family Diabetes Prevention Program Pilot Study

PreDiabetes | Type 2 Diabetes | Obesity, Childhood | Overweight and Obesity | Lifestyle, Healthy | Overweight, Childhood

United States
Sierra Oncology, Inc.

Completed

Efficacy of Momelotinib Versus Best Available Therapy in Anemic or Thrombocytopenic Subjects With Primary Myelofibrosis (MF), Post-polycythemia Vera MF, or Post-essential Thrombocythemia MF (Simplify 2)

Primary Myelofibrosis (PMF) | Post-essential Thrombocythemia Myelofibrosis (Post-ET MF) | Post-polycythemia Vera (Post-PV)

United States, Canada, France, Italy, Germany, Spain, Israel, United Kingdom
G1 Therapeutics, Inc.

Completed

First-in-Human Safety, PK, and Food Effect Study of Single Ascending Doses of G1T38 in Healthy Volunteers

Healthy Volunteers

Netherlands
University of Kansas Medical Center
Kansas State University; National Institute of General Medical Sciences (NIGMS)

Completed

The National Diabetes Prevention Program in Rural Communities (Rural NDPP)

Weight Loss | PreDiabetes | Lifestyle Risk Reduction

United States
Noom Inc.
Stony Brook University

Completed

Prevention of Diabetes Using Mobile-enabled, Virtual Delivery of the National Diabetes Prevention Program

PreDiabetes

United States
GRADE Study Group
Bristol-Myers Squibb; National Institute of Diabetes and Digestive and Kidney... and other collaborators

Completed

A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes (GRADE)

Type 2 Diabetes | Comparative Effectiveness of Glycemia-lowering Medications

United States
Thomas Jefferson University
Bristol-Myers Squibb

Active, not recruiting

Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck

Larynx | Squamous Cell Carcinoma | Lip | Oral Cavity Squamous Cell Carcinoma | Pharynx

United States
Sierra Oncology, Inc.

Terminated

Erlotinib and Momelotinib for the Treatment of Epidermal Growth Factor Receptor (EGFR) Mutated EGFR Tyrosine Kinase Inhibitor (TKI) Naive Metastatic Non-Small Cell Lung Cancer (NSCLC)

EGFR Mutated EGFR TKI Naive Metastatic NSCLC

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Safety and Immunogenicity Study of HIV p17/p24:Ty-VLP in HIV-1 Seronegative Subjects

HIV Infections

United States
Baylor Research Institute

Active, not recruiting

Giving a Low Carbohydrate Diet to Overcome Hypertension (GLOH)

Hypertension | Risk Reduction Behavior | African Americans | Diet, Carbohydrate-Restricted

United States
Maastricht University
Netherlands Brain Foundation

Completed

Roflumilast to Treat Cognitive Sequela After Stroke (ROSTMEMA)

Cerebrovascular Disorders | Functional Recovery | Memory | Drug Intervention

Netherlands

Search clinical trials for: DPP-4 inhibitors

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