Clinical Trials Sponsored by Asten Sante

Total 3257 results

Astex Pharmaceuticals, Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Chronic Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
Aston Sci. Inc.

Not yet recruiting

Adjuvant Therapeutic Cancer Vaccine (AST-201, pUMVC3-hIGFBP-2) in Patients With Advanced Ovarian Cancer (Cornerstone4)

Advanced Ovarian Cancer

United States
Astex Pharmaceuticals, Inc.

Recruiting

A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS, CMML, or AML

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelocytic Leukemia | Myelodysplastic Syndrome/Neoplasm

United States
Astex Pharmaceuticals, Inc.

Active, not recruiting

A Study of Tolinapant in Combination With Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma (R/R PTCL)

Relapsed/Refractory Peripheral T-cell Lymphoma

Spain, United States, Australia, France, United Kingdom, Italy, Poland
Astex Pharmaceuticals, Inc.

Active, not recruiting

Phase 1-2 Study of Low Dose ASTX727 (ASTX727 LD) in Lower Risk MDS

Myelodysplastic Syndromes

Spain, United States, Belgium, Canada, Germany, Italy
Astex Pharmaceuticals, Inc.

Terminated

A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United States
Astex Pharmaceuticals, Inc.

Terminated

A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm

United States, Canada
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in Combination With Carboplatin in Ovarian Cancer (SGI-110)

Ovarian Cancer

Canada, United States, United Kingdom
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in Patients With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)

AML | MDS | CMML

United States, Canada
Astex Pharmaceuticals, Inc.

Completed

Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndrome | MDS

United States, Canada
Astex Pharmaceuticals, Inc.

Completed

A Phase 1 Study to Evaluate the Effect of Food on Pharmacokinetics of ASTX029

Healthy Volunteers

United States
Astex Pharmaceuticals, Inc.

Completed

Safety of MP470 in Combination With Standard-of-Care Chemotherapy Regimens to Treat Solid Tumors (SGI-0470-02)

Malignant Disease

United States
Astex Pharmaceuticals, Inc.

Terminated

Safety of SGI-1776, A PIM Kinase Inhibitor in Refractory Prostate Cancer and Relapsed/Refractory Non Hodgkin's Lymphoma

Prostate Cancer | Non-Hodgkins Lymphoma

United Kingdom, United States
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

United States, United Kingdom, Canada
Astex Pharmaceuticals, Inc.

Terminated

Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemias

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia

United States
Aspen Medical Products

Completed

Effectiveness of Inelastic LSO Versus Standard Medical Treatment for Back Pain Associated With Kyphosis (ARISE)

Back Pain | Kyphosis
Aston Sci. Inc.

Recruiting

Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Patients With Breast Cancer (Cornerstone001)

Breast Cancer

United States, Taiwan
Astex Pharmaceuticals, Inc.

Active, not recruiting

Study of ASTX029 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult

United States, Spain, France, United Kingdom
Astex Pharmaceuticals, Inc.

Active, not recruiting

Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States, Spain, Canada
Astex Pharmaceuticals, Inc.

Active, not recruiting

Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas

Lymphoma | Solid Tumors

United States, Belgium, Spain, Hungary, Italy, Canada, United Kingdom, France
Astex Pharmaceuticals, Inc.

Enrolling by invitation

A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose), With a Food Effect Substudy at Select Study Centers

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States, Spain, Canada, Austria, Slovakia, Bulgaria, Hungary
Astex Pharmaceuticals, Inc.

Completed

Study of ASTX727 vs IV Decitabine in MDS, CMML, and AML

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States, Canada, Spain, Hungary, Austria, Czechia, France, Germany, Italy, United Kingdom
Astex Pharmaceuticals, Inc.

Completed

Phase 3 Randomized, Open-Label Study of Guadecitabine vs Treatment Choice in Previously Treated Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Canada, Belgium, Spain, Germany, Denmark, Korea, Republic of, Hungary, France, Japan, Italy, Poland, Sweden, Ukraine, United Kingdom
Aspen Global Incorporated

Terminated

Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study Safety and Efficacy of Danaparoid vs Argatroban (HITSOVA)

Heparin-induced Thrombocytopenia

United States, Bosnia and Herzegovina, Canada, France, Germany, Italy, Poland, Russian Federation, Serbia
Astex Pharmaceuticals, Inc.

Completed

Thorough QT Assessment of Cedazuridine in Healthy Subjects

Healthy Volunteers

Netherlands
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction

Leukemia, Myeloid, Acute

United States, Spain, Korea, Republic of, Taiwan, Australia, Canada, Denmark, Hungary, Japan, Finland, Italy, Serbia, Czechia, France, Germany, Sweden, Netherlands, Poland, Russian Federation, Austria, United Kingdom, Romania, Belgium, Bulgar...
Astex Pharmaceuticals, Inc.

Terminated

Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHD

Acute Graft Versus Host Disease

United States
Astex Pharmaceuticals, Inc.

Completed

Effect of Food on the Pharmacokinetics of ASTX660 in Healthy Volunteers

Healthy Volunteer

United States
Astex Pharmaceuticals, Inc.

Completed

A Study to Investigate the Effect of CYP3A4 Inhibition on the Single Dose Pharmacokinetics of ASTX660 and the Effect of a Single Dose of ASTX660 on the Pharmacokinetics of the CYP3A4 Substrate Midazolam

Healthy Volunteer

United States
Astex Pharmaceuticals, Inc.

Completed

Effect of Food on Blood Levels of ASTX727

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States
Astex Pharmaceuticals, Inc.

Completed

A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST

Gastrointestinal Stromal Tumor (GIST)

United States
Astex Pharmaceuticals, Inc.

Withdrawn

Study of SGI-1776, a PIM Kinase Inhibitor, in Subjects With Relapsed/Refractory Leukemias

Relapsed/Refractory Leukemias

United States
Astex Pharmaceuticals, Inc.

Completed

Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors

Metastatic Solid Tumors

United States
Aspen Global Incorporated

Completed

A Study Comparing the Local Tolerability of Two Subcutaneous Heparins in Healthy Volunteers.

Injection Site Reaction
Astex Pharmaceuticals, Inc.

Completed

A Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With Crizotinib

Non-small Cell Lung Cancer(NSCLC)

United States, Korea, Republic of, Spain, France, Canada
Aspen Medical Products

Terminated

A Prospective, Multicenter, Randomized Control Study To Determine Clinical Effectiveness, Patient Wellness and Cost of Pain Related Care of In-Elastic Lumbar Sacral Orthoses Versus Standard Medical Treatment in Patients Presenting With Acute Low Back Pain In Primary Care Centers (The ARREST Study) (ARREST)

Back Pain | Low Back Pain
Astex Pharmaceuticals, Inc.

Completed

A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung Cancer (ESCAPE)

Small Cell Lung Carcinoma

United States, Poland
Aspen Medical Products

Completed

Efficacy of Peak Scoliosis Brace in Pain Management For Adult Scoliosis Patients

Back Pain
Astex Pharmaceuticals, Inc.

Completed

Decitabine Versus Supportive Care in Adults With Advanced-stage MDS

Myelodysplastic Syndrome

United States
Astex Pharmaceuticals, Inc.

Completed

Study of Rubitecan in Cancer Patients With Renal or Hepatic Dysfunction

Tumors

United States
AURA Sante

Unknown

Long Term Physical Activity for Hemodialysis Patients

End Stage Renal Disease on Hemodialysis
University Hospital, Montpellier
ADENE, Montpellier; AGIR à dom, Meylan; ASTEN sante, Pays de la Loire; ELIA medical...

Recruiting

The TELEAP1 CPAP-telemonitoring Study (TELEAP1)

Obstructive Sleep Apnea

France
Aston University
TearLab Corporation

Completed

Tear Osmolarity Clinical Utility in Dry Eye Disease

Dry Eye

United Kingdom
Alcon Research
Aston University

Completed

Pre-Lens Tear Film Performance of Silicone Hydrogel Daily Disposable Contact Lenses

Myopia
Hasten Biopharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Mexartan Potassium Tablets (AZL-M) and Calcium Channel Blockers (CCB) in the Treatment of Adults With Essential Hypertension in Chinese Population: a National Multicenter, Prospective, Observational Study

Essential Hypertension

China
Pharmanex
Aspen Clinical Research

Completed

Effects of a Proprietary Blend of Herbal Extract Supplement on Cellular Detoxification, Inflammation, and Cumulative Cognitive Index as Well as Gene Expression in Middle-Aged Adult Women (Pharmanex)

Anti Aging

United States
Aston University
College of Optometrists

Completed

Effect of Peripheral Defocus on Axial Growth in Hyperopes

Hyperopia | Amblyopia | Anisohyperopia

United Kingdom
Astex Pharmaceuticals, Inc.
Eisai Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
Aston University
University of Worcester

Completed

Non-Pharmaceutical Treatment of Seasonal Allergic Conjunctivitis

Hypersensitivity

United Kingdom
Fondation Sante Service

Recruiting

Transverse Study About QOL for Colostomized or Ileostomized Patients During Their Home Hospitalization (STOM'HAD)

Colostomy | Ileostomy | Home Hospitalization

France

Clinical Trials Sponsored by Asten Sante

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