Clinical Trials Sponsored by Gateway Institute for Brain Research

Total 3748 results

Jennifer Lauren Kamens
Gateway for Cancer Research

Recruiting

Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy (PARPAML)

Acute Myeloid Leukemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Gateway for Cancer Research

Active, not recruiting

Electroacupuncture Therapy in Reducing Chronic Pain in Patients After Breast Cancer Treatment

Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Gateway for Cancer Research

Active, not recruiting

TAME: A Pilot Study of Weekly Paclitaxel, Bevacizumab, and Tumor Associated Macrophage Targeted Therapy (Zoledronic Acid) in Women With Recurrent, Platinum-resistant, Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Primary Peritoneal Cancer | Fallopian Tube | Epithelial Ovarian

United States
Washington University School of Medicine
AstraZeneca; Gateway for Cancer Research

Recruiting

Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer

United States
University of Florida
Gateway for Cancer Research; Cellworks Group Inc.

Terminated

iCare for Cancer Patients

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Multiple Myeloma | Myelofibrosis | Acute Myelogenous Leukemia | Acute Lymphoid Leukemia | Leukemia, Acute Lymphoblastic

United States
M.D. Anderson Cancer Center
Gateway for Cancer Research; Theravalues, Inc.

Completed

Phase I Study of Surface-Controlled Water Soluble Curcumin (THERACURMIN CR-011L)

Advanced Cancers

United States
Laureate Institute for Brain Research, Inc.
University of Oklahoma; Stanley Medical Research Institute

Completed

Minocycline and Aspirin in the Treatment of Bipolar Depression (Minocycline)

Bipolar Disorder Depression

United States
GGZ Buitenamstel
Netherlands Institute for Brain Research, Amsterdam, The Netherlands.

Terminated

Light Therapy for Elderly Depression

Major Depressive Disorder

Netherlands
Intra-Cellular Therapies, Inc.
Laureate Institute for Brain Research, Inc.

Completed

Study of ITI-214 in Healthy Volunteers to Determine CNS Engagement

Healthy Volunteers

United States
University of Texas Southwestern Medical Center
Gateway for Cancer Research

Active, not recruiting

HYHOPE: De-intensified Hypofractionated Radiation Therapy for HPV-associated Oropharynx Cancer

Oropharyngeal Cancer | Human Papillomavirus-Related Carcinoma

United States
Therapeutic Advances in Childhood Leukemia Consortium
Gateway for Cancer Research

Completed

A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML

Lymphoblastic Leukemia, Acute, Childhood | Myelogenous Leukemia, Acute, Childhood

United States, Canada, Australia
University of Florida
Gateway for Cancer Research; Cellworks Group Inc.

Withdrawn

iCare 2: Personalized Genomic Mutation Informed Treatment of Patients With Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
University of Alabama at Birmingham
National Cancer Institute (NCI); Gateway for Cancer Research

Recruiting

Trial of C134 in Patients With Recurrent GBM (C134-HSV-1)

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
Lawson Health Research Institute
Ontario Brain Institute

Completed

Clinic to Community© Program for Adults With Epilepsy Admitted to Emergency Departments (C2CEDRCT)

Epilepsy, Generalized

Canada
Laureate Institute for Brain Research, Inc.
National Institute of Mental Health (NIMH)

Completed

Self-regulation of Prefrontal Cortex During Emotional Cognitive Control (SPrC)

Healthy Volunteers | Cognitive Function

United States
Laureate Institute for Brain Research, Inc.
National Institute of Mental Health (NIMH)

Completed

Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response

Generalized Anxiety Disorder

United States
Laureate Institute for Brain Research, Inc.
National Institute of Mental Health (NIMH)

Completed

Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa

Anorexia Nervosa | Brain Injury | Generalized Anxiety Disorder | Major Depressive Disorder | Panic Disorder

United States
Laureate Institute for Brain Research, Inc.
National Institute of Mental Health (NIMH)

Completed

Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases

Major Depressive Disorder

United States
Laureate Institute for Brain Research, Inc.
National Institute of Mental Health (NIMH)

Recruiting

Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT) (AAC-BeT)

Depression | Anxiety

United States
Lawson Health Research Institute
Brain Canada

Not yet recruiting

M3-JIA: Making Mindfulness Matter for Children With JIA (M3-JIA)

Children | Mental Health | Juvenile Idiopathic Arthritis | Mental Well-being

Canada
Dr. Brian Hallahan
Stanley Medical Research Institute; National University of Ireland, Galway,... and other collaborators

Recruiting

Scopolamine in Bipolar Depression (SCOPE-BD)

Bipolar Disorder Depression

Ireland
Nicholas DeVito, MD
Gateway for Cancer Research; Agenus Inc.

Not yet recruiting

Botensilimab and Balstilimab Optimization in Colorectal Cancer (BBOpCo)

Colorectal Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
University of South Florida; Gateway for Cancer Research

Completed

COGNUTRIN in Breast Cancer Survivors

Breast Cancer

United States
Dana-Farber Cancer Institute
Gateway for Cancer Research; Susan G. Komen Breast Cancer Foundation

Active, not recruiting

ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer

Breast Cancer

United States
St. Jude Children's Research Hospital
AbbVie; Gateway for Cancer Research; Karyopharm Therapeutics Inc

Recruiting

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Refractory Acute Myeloid Leukemia | Acute Myeloid Leukemia, in Relapse | Acute Leukemia of Ambiguous Lineage in Relapse | Refractory Acute Leukemia of Ambiguous Lineage

United States
St. Jude Children's Research Hospital
Baylor College of Medicine; Gateway for Cancer Research

Active, not recruiting

Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I

Acute Lymphoblastic Leukemia

United States, Canada
Laureate Institute for Brain Research, Inc.
National Center for Complementary and Integrative Health (NCCIH)

Active, not recruiting

Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression

Generalized Anxiety Disorder | Major Depressive Disorder | Posttraumatic Stress Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia

United States
Laureate Institute for Brain Research, Inc.
National Institute of General Medical Sciences (NIGMS)

Not yet recruiting

Mood and Decision-making in Methamphetamine Use Disorder (MDM-MUD)

Methamphetamine Abuse

United States
Laureate Institute for Brain Research, Inc.
National Institute of General Medical Sciences (NIGMS)

Recruiting

Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression (CNF-RNT)

Depressive Disorder, Major

United States
Laureate Institute for Brain Research, Inc.
National Institute of General Medical Sciences (NIGMS)

Completed

Augmented Mindfulness Training for Resilience in Early Life (A-MindREaL)

Adolescents With Early Life Stress

United States
Laureate Institute for Brain Research, Inc.
National Institute of General Medical Sciences (NIGMS)

Completed

Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression

Depression | Anxiety and Fear

United States
Carrick Institute for Graduate Studies
Carrick Brain Centers

Completed

Study of PTSD in Military Veterans Who Have Suffered Traumatic Brain Injuries (PTSD-TBI)

PTSD | TBI

United States
Carrick Institute for Graduate Studies
Carrick Brain Centers

Completed

Vestibular Rehabilitation Strategies in PTSD Effectiveness of Carrick Brain Centers Strategies Vestibular Rehabilitation Treatment in PTSD Patients Who Have Suffered Combat Related Traumatic Brain Injuries

Post Traumatic Stress Disorder PTSD

United States
University of Texas Southwestern Medical Center
Gateway for Cancer Research; Celldex Therapeutics

Recruiting

CD40 Agonist, Flt3 Ligand, and Chemotherapy in Triple Negative Breast Cancer

Metastatic Triple Negative Breast Cancer

United States
Max Planck Institute for Human Cognitive and Brain...
European Research Council

Completed

Plasticity of the Compassionate Brain

Healthy Subjects

Germany
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Brain... and other collaborators

Recruiting

Promoting Resilience in Youth Through Mindfulness mEditation (PRYME)

Internalizing Problems

Netherlands
Yuan Yuan
Gateway for Cancer Research; Agenus Inc.

Recruiting

Ivermectin and Balstilimab for the Treatment of Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma

United States
Yuanquan Yang
Gateway for Cancer Research

Not yet recruiting

Futibatinib in Combination With Durvalumab Prior to Cystectomy for the Treatment of Muscle-Invasive Bladder Cancer Patients Who Are Ineligible for Cisplatin-based Therapy

Bladder Urothelial Carcinoma | Stage IIIA Bladder Cancer AJCC v8 | Muscle Invasive Bladder Carcinoma | Stage II Bladder Cancer AJCC v8

United States
Laureate Institute for Brain Research, Inc.
Oklahoma Center for the Advancement of Science and Technology

Completed

Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder (NEAT)

Opioid-use Disorder | Amphetamine Use Disorders

United States
Toronto Rehabilitation Institute
Canadian Institutes of Health Research (CIHR); Centre for Aging and Brain Health... and other collaborators

Completed

Nurse Practitioner Led Implementation of Team Huddles in Long-Term Care Homes

Mental Health | Physical Health | Job Satisfaction | Moral Distress | Support

Canada
Diwakar Davar
Merck Sharp & Dohme LLC; Gateway for Cancer Research

Not yet recruiting

Pembrolizumab/Lenvatinib With and Without Responder-derived FMT in Relapsed/Refractory Melanoma

PD-1 Refractory Advanced Melanoma

United States
Max Planck Institute for Human Cognitive and Brain...

Completed

High-fiber Diet on the Body and the Brain

Overweight | Diet Modification

Germany
Sheppard Pratt Health System
Lieber Institute for Brain Development

Unknown

A Trial Evaluating Effects of COMT Inhibition in Patients With Acquired Brain Injury

Brain Injuries | Brain Injuries, Traumatic | Brain Injury, Chronic

United States
Coventry University
Donders Institute for Brain, Cognition and Behavior

Unknown

Psychobiological Effects of Meditation on Offenders With Psychopathy

Yoga | Mindfulness
The Hospital for Sick Children
Ehave; Ontario Brain Institute

Completed

Cognitive Restructuring in ADHD: Functional Training (CRAFT)

Attention-deficit Hyperactivity Disorder

Canada
Charles Taylor
Laureate Institute for Brain Research, Inc.

Suspended

Amplification of Positivity for Alcohol Use Disorder Co-Occurring With Anxiety or Depression

Substance-Related Disorders | Depression | Alcohol Drinking | Drinking Behavior | Alcoholism | Alcohol-Related Disorders | Anxiety | Mental Disorder

United States
Laureate Institute for Brain Research, Inc.
National Institute of Mental Health (NIMH); California Institute of Technology

Recruiting

Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression

Depression | Anxiety Disorders | Fear | Depression, Anxiety | Anxiety and Fear | Anxious Depression

United States
Centre for Addiction and Mental Health
Brain & Behavior Research Foundation

Recruiting

Repetitive Transcranial Magnetic Stimulation for Cannabis Use Disorder

Cannabis Use Disorder

Canada
Washington University School of Medicine
Gateway for Cancer Research; Servier Hellas Pharmaceuticals Ltd.

Recruiting

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Clonal Cytopenia of Undetermined Significance

United States
Ontario Neurodegeneration Disease Research Initiative
Ontario Brain Institute

Terminated

Health in Aging, Neurodegenerative Diseases and Dementias In Ontario (HANDDS-ONT)

Dementia | Neuro-Degenerative Disease

Canada

Clinical Trials Sponsored by Gateway Institute for Brain Research

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