Clinical Trials Sponsored by Ortho Biotech, Inc.

Total 529 results

Rheumazentrum Ruhrgebiet
Centocor Ortho Biotech Services, L.L.C.

Unknown

European Ankylosing Spondylitis Infliximab Cohort (EASIC) Follow up Registration Study (EASIC registry)

Ankylosing Spondylitis

Belgium, Germany, Finland, France, Netherlands, United Kingdom
Centocor Ortho Biotech Services, L.L.C.
Schering-Plough

Completed

RESTART C0168Z05 Rheumatoid Arthritis Study

Rheumatoid Arthritis

United States, United Kingdom, Spain, Israel, Finland, Canada, France, Austria, Germany, Netherlands
Mayo Clinic
Centocor Ortho Biotech Services, L.L.C.

Completed

Intestinal Wall Remodeling (Infliximab Therapy) in Crohn's Disease Patients Undergoing Serial Computed Tomography (CT) Enterography

Crohn's Disease

United States
Theratocular Biotek Co.

Recruiting

A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD)

Age-Related Macular Degeneration

Thailand
Janssen-Ortho LLC
Ortho-McNeil Neurologics, Inc.

Completed

A Study of 3 Dosage Strengths of Almotriptan Malate (AXERT®) in the Treatment of Acute Migraine in Adolescents

Migraine
UNC Lineberger Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Millennium Pharmaceuticals, Inc.; Ortho Biotech, Inc.

Terminated

Vorinostat, Bortezomib, and Doxorubicin Hydrochloride Liposome in Treating Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Janssen-Ortho LLC
Ortho-McNeil Neurologics, Inc.

Completed

A 1-year Study in Adolescents to Assess the Long-term Safety of Almotriptan Malate When Treating Their Migraine Headaches

Migraine

United States
Janssen-Ortho LLC
Ortho-McNeil Neurologics, Inc.

Completed

A Study of the Effectiveness and Safety of Almotriptan Versus Placebo in the Treatment of Migraine Headache

Migraine
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Ortho Biotech, Inc.

Completed

Rituximab and Combination Chemotherapy in Treating Older Patients With Diffuse Large B-Cell Lymphoma

Lymphoma

United States
University Health Network, Toronto
Princess Margaret Hospital, Canada; Ortho Biotech, Inc.

Completed

Combination Bortezomib-containing Regimens in Newly Diagnosed Patients With t (4; 14) Positive Multiple Myeloma

Multiple Myeloma

Canada
Aptium Oncology Research Network
Ortho Biotech Products, L.P.

Unknown

Phase II Study in Patients With Operable Breast Cancer

Breast Cancer

United States
Brigham and Women's Hospital
Ortho Biotech Products, L.P.

Terminated

Erythropoietin in Radiocontrast Induced Nephropathy (ERIN) Trial (ERIN)

Contrast Induced Nephropathy

United States
University of Rochester
Centocor Ortho Biotech Services, L.L.C.

Completed

Monroe County Inflammatory Bowel Disease (IBD) Registry

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease
University of Florida
Ortho Biotech Clinical Affairs, L.L.C.

Completed

Pilot Study of Epoetin Alfa for Patients Having Abdominal or Pelvic Surgery for Cancer

Anemia

United States
Janssen-Ortho Inc., Canada

Terminated

An Efficacy and Safety Study of Bortezomib in Participants Previously Treated for Multiple Myeloma With Limited Kidney Function

Multiple Myeloma

Canada
Janssen-Ortho Inc., Canada

Completed

A Study to Monitor Intragastric pH in Patients Taking Rabeprazole vs. Patients Taking Pantoprazole

GERD
Janssen-Ortho Inc., Canada

Completed

Open Label Study Evaluating Different Dosing Regimens of Rabeprazole in Gastro-esophageal Reflux Disease (GERD) Patients With Night-time Heartburn Symptoms.

Gastroesophageal Reflux | Heartburn
Janssen-Ortho Inc., Canada

Completed

A Safety and Efficacy Study for Epoetin Alfa in Pre-dialysis Subjects.

Anemia | Kidney Failure | Left Ventricular Hypertrophy
Janssen-Ortho Inc., Canada

Completed

A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD)

Autistic Disorder | Developmental Disabilities | Rett Syndrome | Asperger Syndrome | DCild Development Disorders, Pervasive
Janssen-Ortho Inc., Canada

Completed

An Open-label Study Evaluating the Maintenance of Clinical Effect in Adult Schizophrenia Patients Switched From Risperidone Tablets to an Equivalent Dose of a Rapidly-dissolving Tablet Formulation of Risperdone

Schizophrenia
Ortho-Clinical Diagnostics, Inc.

Unknown

VITROS Immunodiagnostic Products hs Troponin I

Myocardial Infarction | Acute Coronary Syndrome (ACS)

United States
Janssen-Ortho Inc., Canada

Withdrawn

A Study to Determine an Effective Dose of Epoetin Alfa to Decrease the Number of Units of Blood Required to be Transfused During Hip Replacement Surgery.

Anemia | Blood Transfusion | Orthopedic Surgery
Janssen-Ortho Inc., Canada

Completed

A Study to Determine the Short-Term Safety of Continuous Dosing of Abiraterone Acetate and Prednisone in Modified Fasting and Fed States to Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer | Prostate Neoplasms

Canada
Janssen-Ortho Inc., Canada

Completed

A Trial Comparing Risperidone Long-Acting Injection With Oral Antipsychotic in the Treatment of Early Psychosis

Psychotic Disorders | Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder

Canada
Janssen-Ortho Inc., Canada

Completed

CONCERTA (OROS Methylphenidate Hydrochloride) for the Treatment of Attention Deficit Hyperactivity Disorder in Adults

Attention Deficit Disorder With Hyperactivity
Ortho-McNeil Neurologics, Inc.

Completed

A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Preventing Migraine Headaches in Children

Migraine
Ortho-McNeil Neurologics, Inc.

Completed

Evaluation of the Effectiveness of Topiramate in Preventing the Transformation From Episodic Migraine to Chronic Daily Headache.

Migraine | Headache | Common Migraine | Classic Migraine
Janssen-Ortho Inc., Canada

Completed

A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo to Reduce the Need for Blood Transfusions and Reduce the Occurrence of Severe Anemia During the Time Period Surrounding Total Hip Replacement Surgery

Anemia
Janssen-Ortho Inc., Canada

Completed

An Open-label Study to Evaluate Topiramate Therapy in Migraine Patients, and Its Effects on Subject Responsiveness to Migraine Treatment With Triptans

Headache
Janssen-Ortho Inc., Canada

Completed

CONCERTA® (Methylphenidate Hydrochloride) as add-on Therapy in the Treatment of Adult Major Depressive Disorder.

Depressive Disorder, Major
Janssen-Ortho Inc., Canada

Completed

An Effectiveness and Safety Study of CONCERTA* vs. Immediate Release Methylphenidate (IR MPH) in Attention Deficit Hyperactivity Disorder Children

Attention Deficit Hyperactivity Disorder
Janssen-Ortho Inc., Canada

Completed

A Randomized, Open-label Trial of Long-acting Injectable Risperidone Versus Oral Antipsychotic Medication in Patients With Bipolar Disorder

Bipolar Disorder
Ortho-Clinical Diagnostics, Inc.

Completed

VITROS Immunodiagnostic Products NT-proBNP II

Heart Failure

United States
Janssen-Ortho Inc., Canada

Terminated

A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Participants With a History of Being Poorly Compliant With Taking Their Medication

Schizophrenia

Canada, United Kingdom, Australia, Ireland
Janssen-Ortho Inc., Canada

Completed

Impact of Tolerability Issues on Chronic Pain

Pain
Ortho-McNeil Neurologics, Inc.

Completed

Use of Different Treatment Care Methods in Patients With Dementia Associated With Alzheimer's Disease (REMIND)

Dementia | Alzheimer's Disease
Janssen-Ortho Inc., Canada

Completed

A Study to Explore Plasma Levels of CONCERTA, Ritalin-SR and Novo-Methylphenidate ER-C in Healthy Volunteers

Pharmacokinetics
Janssen-Ortho Inc., Canada

Completed

A Study Assessing Safety and Effectiveness of BORTEZOMIB Combination Therapy (Bortezomib + Doxorubicin Hydrochloride + Dexamethasone) in Previously Untreated Multiple Myeloma Patients

Multiple Myeloma
Ortho-McNeil Neurologics, Inc.

Completed

The Effectiveness of Almotriptan Malate (AXERT®) 12.5 Milligrams When Taken at the Onset of Migraine Pain

Migraine
Ortho-McNeil Neurologics, Inc.

Completed

Topiramate Versus Placebo as add-on Treatment in Patients With Bipolar Disorder in the Outpatient Setting

Bipolar Disorder
Janssen-Ortho Inc., Canada

Completed

An Open-label, Multicentre Study on Preference and Satisfaction of Canadian Women for the Transdermal Contraceptive Patch vs. Previous Primary Contraceptive Method

Female Contraception
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Changes in Triglyceride and Other Lipids (Levels of Fats Found in Blood) When Taking Darunavir Compared to Atazanavir in HIV-infected Patients That Have Never Received Treatment

HIV

United States
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

GRACE: A Study to Compare the Effectiveness, Safety and Tolerability of PREZISTA (Darunavir)/Ritonavir by Gender and Race When Administered With Other Antiretroviral Medications in Human Immunodeficiency Virus (HIV) Positive Women and Men.

HIV | Infectious

United States, Canada, Puerto Rico
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Study of the Once Daily Combination of Etravirine and Darunavir/Ritonavir As Dual Therapy in Early Treatment-Experienced Patients (INROADS)

Human Immunodeficiency Virus (HIV)

United States, Puerto Rico
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Phase I, Open-label Trial to Explore the Pharmacokinetics, Safety and Tolerability of TMC278 (Rilpivirine) 25 mg Once Daily Following a 2-week Period Receiving Efavirenz, in Healthy Male and Female Volunteers

HIV
H. Lee Moffitt Cancer Center and Research Institute
Millennium Pharmaceuticals, Inc.; Ortho Biotech, Inc.

Completed

Cyclophosphamide, VELCADE, DOXIL, and Dexamethasone, (CVDD) in Newly Diagnosed Patients With Multiple Myeloma (MM)

Multiple Myeloma

United States
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Enfuvirtide/Current Protease Inhibitor Switch to PREZISTA (Darunavir)/Ritonavir + TMC125 in HIV Patients With Enfuvirtide Side Effects.

HIV

United States
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).

HIV-1 Infection
University of Manitoba
Janssen-Ortho Inc., Canada; PriCara, Unit of Ortho-McNeil, Inc.; Ortho-McNeil...

Terminated

Safety and Efficacy Study of the Treatment of Kidney Infections With Short Course Levofloxacin

Acute Uncomplicated Pyelonephritis

Canada
Morton Plant Mease Health Care
Ortho Biotech Products, L.P.

Terminated

Liposomal Doxorubicin and Estramustine Phosphate: Study in Taxane Resistant, Hormone Refractory Advanced Prostate Cancer

Prostate Cancer

United States

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