Clinical Trials Sponsored by Rottapharm Biotech

Total 1821 results

Impact Biotech Ltd
Impact biotech Ltd.

Active, not recruiting

Padeliporfin VTP Treatment for Unresectable Pancreatic Adenocarcinoma

Locally Advanced Unresectable Pancreatic Adenocarcinoma

United States
SOTIO Biotech AG

Active, not recruiting

A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer

Colorectal Cancer

France, Spain, Belgium
Neovii Biotech
Fresenius Biotech North America

Completed

Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites

Malignant Ascites

United States
Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells (BAH246)

T Cell Lymphoma | T Cell Prolymphocytic Leukemia | T-cell Acute Lymphoblastic Leukemia | T Cell Leukemia | T-Cell Lymphoma of CNS | T Cell Childhood ALL

China
Aurion Biotech

Recruiting

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1) (CLARA)

Corneal Edema | Corneal Endothelial Dysfunction

United States, Canada
Meccellis Biotech

Recruiting

Safety and Clinical Performance of a Biological Matrix Used in Implant-based Breast Reconstruction

Breast Reconstruction Following Mastectomy

France
ElsaLys Biotech

Not yet recruiting

Evaluation of EFficacy and SaFEty of Leukotac (Inolimomab) in Pediatric Patients With SR-aGvHD (EiFFEL)

Steroid Refractory GVHD
J2H Biotech

Completed

Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males

Non-alcoholic Steatohepatitis

Korea, Republic of
CEN Biotech

Completed

Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus. (TINNITY)

Tinnitus

France
Aurion Biotech

Completed

A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction (Escalon)

Corneal Edema

El Salvador
Biotech Dental

Completed

Performance and Safety of Use of the "KONTACT PERIO LEVEL" Transgingival Titanium Dental Implant (KPL)

Tooth Loss | Partially Edentulous Maxilla | Partially Edentulous Mandible

France
Acticor Biotech

Completed

Acute Ischemic Stroke Interventional Study (ACTIMIS)

Acute Ischemic Stroke

France
Oncolytics Biotech

Completed

Study of Pembrolizumab With REOLYSIN® and Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma

Pancreatic Adenocarcinoma

United States
Cinfa Biotech

Completed

Immunogenicity and Pharmacodynamic of B12019 and Neulasta® in Healthy Subjects

Healthy Volunteers

Germany
Activartis Biotech

Completed

Cancer Immune Therapy for the Treatment of Refractory Solid Tumours of Childhood

Childhood Solid Tumor

Austria
Trinity Biotech

Completed

99th Percentile Upper Reference Limit (URL) for the Meritas Troponin I Test

Acute Coronary Syndrome

United States
Oncolytics Biotech

Completed

Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung

Osteosarcoma | Leiomyosarcoma | Fibrosarcoma | Sarcoma, Synovial | Ewing Sarcoma Family Tumors | Malignant Fibrous Histiocytoma

United States
Neovii Biotech

Completed

Phase II Study With Catumaxomab in Patients With Gastric Cancer After Neoadjuvant CTx and Curative Resection

Gastric Cancer | Gastric Adenocarcinoma

Austria, Spain, United Kingdom, Germany
Neovii Biotech

Terminated

A Open Label, Dose Escalating Study to Evaluate the Safety and Tolerability of Ascending Intravenous (i.v.) Doses of Catumaxomab in Epithelial Cancer Patients

Epithelial Cancer Patients

Austria, Denmark, Spain
Neovii Biotech

Completed

Phase II Study of the Trifunctional Antibody Catumaxomab Administered Intra- and Postoperatively in Patients With Ovarian Cancer

Ovarian Cancer | Epithelial Ovarian Cancer

Austria, Germany
Neovii Biotech

Completed

EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection

Bronchiectasis | Idiopathic Pulmonary Fibrosis | Cystic Fibrosis | Chronic Obstructive Pulmonary | Pulmonary Vascular Disease

United States, Australia, Austria, Canada
Facet Biotech

Completed

A Humanized Anti-Interferon-γ Monoclonal Antibody (HuZAF) for Moderate to Severe Crohn's Disease

Crohn's Disease | Colitis | Digestive System Disease | Gastrointestinal Disease | Intestinal Disease

United States, Canada
Facet Biotech

Completed

Study of Daclizumab in Patients With Chronic, Persistent Asthma

Asthma

United States
Facet Biotech

Completed

Pilot Study in Patients With Symptomatic Steroid-Naive Asthma

Asthma

United States
Stryker Biotech

Completed

Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee

Osteoarthritis of the Knee

United States
Stryker Biotech

Completed

A Phase 1, Double-Blind, Randomized, Single Dose Escalation Safety Study of Intra-articular OP-1 in Subjects With Osteoarthritis of the Knee (Knee OA)

Osteoarthritis of the Knee

United States
Facet Biotech

Completed

Phase I, Multi-Center, Open-Label, Dose Escalation Study of HuLuc63 in Subjects With Advanced Multiple Myeloma

Multiple Myeloma

United States
Neovii Biotech

Completed

Study in EpCAM Positive Patients With Symptomatic Malignant Ascites Using Removab Versus an Untreated Control Group

Malignant Ascites | EpCam Positive Tumor (e.g.Ovarian, Gastric, Colon, Breast)
Essen Biotech

Recruiting

Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases (BAH247)

Autoimmune Diseases | Systemic Lupus Erythematosus | Sjogren's Syndrome | Systemic Lupus Erythematosus Acute

China
Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML (BAH244)

Acute Myeloid Leukemia | AML | AML, Adult | AML, Adult Recurrent

China
Essen Biotech

Not yet recruiting

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease (BAH243)

Sickle Cell Disease | Sickle-Cell Disease With Crisis

China
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) (BAH242)

Autoimmune Diseases | Systemic Lupus Erythematosus | Systemic Sclerosis | Lupus Nephritis | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Granulomatous Polyangiitis

China
Swalife Biotech

Not yet recruiting

Observe the Effect of Wheatgrass and Tulsi Formulation or Individuals Taken With Other Allopathic Drugs

Smoking | Blood Sugar; High | Blood Pressure, High | Weight, Birth

India
Cousin Biotech

Recruiting

Laparoscopic Inguinal and Femoral heRniA rePaIr Using Pre-shapeD 4DMESH® (4DLap)

Inguinal Hernia | Femoral Hernia

Belgium, Spain, France
Biotech Dental

Recruiting

Performance and Safety Use of the Mono Block Implant "KONTACT MB"

Dental Implant | Dental Restoration | Dentistry | Implant-supported Fixed Prosthesis

France
Meccellis Biotech

Recruiting

Safety and Clinical Performance of a Biological Matrix Used in Abdominal Wall Reconstruction (PMCF_AWR)

Abdominal Hernia | Abdominal Wall Defect | Abdominal Wall Injury

France
J2H Biotech

Completed

Phase 1 Study to Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females

Non-alcoholic Steatohepatitis

Korea, Republic of
Acticor Biotech

Active, not recruiting

ACTISAVE: ACuTe Ischemic Stroke Study Evaluating Glenzocimab Used as Add-on Therapy Versus placEbo (ACTISAVE)

Acute Ischemic Stroke

United States, Germany
Meccellis Biotech

Completed

Safety and Performance Evaluation of a Biological Matrix Used for Rectal Prolapse Repair by Ventral Rectopexy

Rectal Prolapse

France
Biotech Dental

Completed

Performance and Safety Use of the Nanostructured Titanium Dental Implant "KONTACT N"

Dental Implant | Edentulous Alveolar Ridge | Dental Restoration | Implant-supported Fixed Prosthesis

France
ElsaLys Biotech

Available

Early Access Program With Inolimomab in Steroid-refractory Acute Graft Versus Host Disease

Steroid Resistant Acute Graft Versus Host Disease

France
Vaxon Biotech

Completed

Efficacy Study of Vx001 Vaccine in NSCLC Patients

Non-small Cell Lung Cancer Metastatic

Germany, Greece, Spain, Romania, France, Italy, Czechia, Poland
Vaxon Biotech

Completed

Safety Study of Vx006 Vaccine in Solid Tumor Patients

Solid Tumor

Greece
Cinfa Biotech

Completed

Pharmacokinetic and Pharmacodynamics of B12019 and Neulasta® in Healthy Subjects

Clinical Pharmacology

Germany
Oncolytics Biotech

Withdrawn

Study of Intratumoral REOLYSIN® in Combination With Gemcitabine and Cisplatin as Neoadjuvant Therapy in Muscle-invasive Transitional Cell Carcinoma of the Bladder

Muscle-invasive Transitional Cell Carcinoma of the Bladder
Oncolytics Biotech

Completed

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin for Non-Small Cell Lung Cancer With KRAS or EGFR Activation

Carcinoma, Non-small Cell Lung

United States
Neovii Biotech

Terminated

Safety and Efficacy Study of the Trifunctional Antibody Ertumaxomab to Treat Patients With Advanced or Metastatic Breast Cancer (IV REXBC 02)

Breast Cancer | Breast Neoplasms

Belgium
Oncolytics Biotech

Completed

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers

Carcinoma, Squamous Cell of the Head and Neck

United States, Canada, Spain, Belgium, United Kingdom, Greece, Germany, Hungary, Poland, Slovenia, France, Italy, Russian Federation
Puleva Biotech

Completed

Safety of Lactobacillus Fermentum in Newborn Infants

Tolerance

Spain
Neovii Biotech

Completed

CASIMAS: Catumaxomab Safety Phase IIIb Study With Intraperitoneal Infusion in Patients With Malignant Ascites Due to Epithelial Cancers (CASIMAS)

Neoplasms | Carcinoma | Cancer | Malignant Ascites

France, Germany, Italy, Spain

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