Clinical Trials Sponsored by Royal Free Charity

Total 122 results

Royal Brompton & Harefield NHS Foundation Trust
GlaxoSmithKline; CORDA, The Heart Charity

Unknown

Rosiglitazone Plaque Study

Vascular Diseases | Hypertension | Diabetes Mellitus, Type 2

United Kingdom
Royal Free Hampstead NHS Trust
Bristol-Myers Squibb; Sigma-Tau Research, Inc.

Unknown

ALCAR Prophylaxis Study

HIV Infections | Distal Symmetric Polyneuropathy

United Kingdom
Royal Free Hospital NHS Foundation Trust
Merck Sharp & Dohme LLC; University College, London

Completed

Immunophenotyping of Melanoma Patients on Treatment With Pembrolizumab (PASIP)

Melanoma | Neoplasms

United Kingdom
Royal Free Hospital NHS Foundation Trust
Massachusetts General Hospital; University College London Hospitals

Not yet recruiting

International Pancreatic Surgery Outcomes Study - PancreasGroup.Org

Pancreatic Neoplasms | Pancreatitis
University College, London
Royal Free Hospital NHS Foundation Trust; St. Bartholomew's Hospital; UCLH

Recruiting

COVID-19: Healthcare Worker Bioresource: Immune Protection and Pathogenesis in SARS-CoV-2 (COVID19-HCW)

Coronavirus Infections | Coronavirus | Immunological Abnormality | Health Care Worker Patient Transmission

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Free and University College Medical School

Completed

Targeted Radiotherapy in HSCT for Poor Risk Haematological Malignancy

Lymphoma | Myeloma | Acute Leukaemia | Chronic Leukaemia

United Kingdom
Tara Mastracci
University Hospital, Lille; Skane University Hospital

Not yet recruiting

Longitudinal Registry of Endovascular Thoracoabdominal Aneurysms (LoRETA)

Aneurysm | Aortic Aneurysm
University College, London
Medical Research Council; Royal Free Hospital NHS Foundation Trust; ViiV Healthcare

Completed

Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV (MAVMET)

Hepatic Steatosis | HIV-1-infection

United Kingdom
University of Edinburgh
Royal Free Hospital NHS Foundation Trust; National Health Service, United Kingdom

Active, not recruiting

The Effect of Varying Brightness on Palpebral Aperture

Eyelid Ptoses

United Kingdom
GlaxoSmithKline
Quintiles, Inc.; Imperial College London; Royal Free Hospital NHS Foundation... and other collaborators

Completed

A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis

Amyloidosis

United Kingdom
University Hospital Birmingham
Royal Free Hospital NHS Foundation Trust; University of Edinburgh; University...

Unknown

Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD (SPIRO-CKD)

Renal Insufficiency, Chronic | Cardio-Renal Syndrome

United Kingdom
Royal Free Hospital NHS Foundation Trust
University Hospital Tuebingen; Imperial College Healthcare NHS Trust; Ankara...

Unknown

Accuracy of the LiverVision® Semi-automated Liver Volumetry Software (LiverVision)

Liver Diseases | Liver Cancer

Germany, United Kingdom, Turkey
King's College London
Guy's and St Thomas' NHS Foundation Trust; Royal Free Hospital NHS Foundation...

Recruiting

Pericarditis: Auto-Inflammation in Recurrent Disease (PAIReD)

Idiopathic Recurrent Pericarditis

United Kingdom
Videregen Limited
Royal Free Hospital NHS Foundation Trust; Papworth Hospital NHS Foundation... and other collaborators

Not yet recruiting

ENgineered Tissue Repair of BronchopleUral fiSTula (ENTRUST)

Bronchopleural Fistula
University College, London
University of Cambridge; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Development of an Optimal Antibiotic Regime for Long-term Therapy in Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD).

United Kingdom
The Christie NHS Foundation Trust
University College London Hospitals; University College, London; Royal Free Hospital...

Not yet recruiting

Evaluation of Combined Modality Protons and Hepatic Transplantation for Hilar Cholangiocarcinoma (EMPHATIC)

Cholangiocarcinoma
Royal Marsden NHS Foundation Trust
St George's, University of London; Mologic Ltd; The Royal Marsden Cancer Charity and other collaborators

Completed

Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19) (CARDS)

Coronavirus Infection | Cancer | Infectious Disease

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Janssen Research & Development, LLC; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

ADOPT: Improving Diagnosis of Pulmonary Hypertension With AI and Echo (ADOPT)

Pulmonary Hypertension

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Royal Free Hospital NHS... and other collaborators

Recruiting

Improving Pulmonary Hypertension Screening by Echocardiography (IMPULSE)

Pulmonary Hypertension

United Kingdom
Charite University, Berlin, Germany
NeuroCure Clinical Research Center, Charite, Berlin; Humboldt-Universität zu... and other collaborators

Terminated

Computerised Assessment of Visual Neglect Symptoms in Peripersonal Space (KMS-Neglect 2)

Visual Neglect

Germany
UMC Utrecht
Radboud University Medical Center; University Medical Center Groningen; Royal... and other collaborators

Recruiting

Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)

Systemic Sclerosis

Netherlands
Dr Eoin R Hyde
Royal Free Hospital NHS Foundation Trust; National Institute for Health Research...

Completed

3D Virtual Models as an Adjunct to Preoperative Surgical Planning

Kidney Neoplasms | Surgical Oncology

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
University of Surrey; Bowel Cancer Screening Hub; GUTS Fighting Bowel Cancer...

Completed

Point of Care Faecal Immunochemical Testing for Colorectal Cancer (POCFIT)

Colorectal Cancer

United Kingdom
Perspectum
Royal Free Hospital NHS Foundation Trust; Liverpool University Hospitals NHS... and other collaborators

Active, not recruiting

Longitudinal Assessment of Multiple Organs in Patients With Type 2 Diabetes (MODIFY)

Type 2 Diabetes

United Kingdom
University College, London
Barts & The London NHS Trust; University Hospitals Bristol and Weston NHS Foundation... and other collaborators

Completed

RCT of Stent Versus Standard Therapy in Oesophageal Variceal Haemorrhage (SOV)

Acute Bleeding Esophageal Varices

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; Royal Free Hospital NHS... and other collaborators

Not yet recruiting

Developing the Probability Algorithm for Pulmonary Hypertension Echocardiography (DRAPE)

Pulmonary Hypertension

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
CORDA, The Heart Charity; Apotex Inc.; The Cooley's Anemia Foundation,; The UK...

Unknown

Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major

Beta-Thalassemia

Italy
Charite University, Berlin, Germany
Freie Universität Berlin; NeuroCure Clinical Research Center, Charite, Berlin; Humboldt-Universität zu Berlin and other collaborators

Completed

Virtual Reality for Neglect Diagnostics (KMS-Neglect)

Stroke | Spatial Neglect

Germany
The Royal Wolverhampton Hospitals NHS Trust
Imperial College London; University of Oxford; University of Leicester; Neonatal... and other collaborators

Active, not recruiting

OPTI-Prem: Optimising Neonatal Service Provision for Preterm Babies Born Between 27 and 31 Weeks of Gestation in England (OPTI-Prem)

Neonatal Diseases and Abnormalities

United Kingdom
German Institute of Human Nutrition
Charite University, Berlin, Germany; Freie Universität Berlin; German Center...

Recruiting

Breathing and Decision-Making (ProlEx-MRI)

Quality of Life | Stress, Psychological | Behavior

Germany
Ourotech, Inc.
Royal Free Hospital NHS Foundation Trust; Imperial College Healthcare NHS Trust and other collaborators

Not yet recruiting

Prospective Evaluation of AI R&D Tool for Patient Stratification: a Trial for Renal Immuno-oncology Model Experimental Evaluation 2 (PEAR-TREE2)

Kidney Cancer | Renal Cell Cancer Metastatic

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Not yet recruiting

Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina (ORBITA-MOON)

Stable Angina | Multivessel Coronary Artery Disease

United Kingdom
King's College London
Royal Free Hospital NHS Foundation Trust; Chelsea and Westminster NHS Foundation... and other collaborators

Recruiting

Muscle Connective Tissue in Limb Development and Disease

Radial Dysplasia

United Kingdom
Imperial College London
Royal Free Hospital NHS Foundation Trust; Mid and South Essex NHS Foundation... and other collaborators

Recruiting

Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina (ORBITA-FIRE)

Stable Angina

United Kingdom
AJAY YERRAMASU
Royal Free Hospital NHS Foundation Trust; Barnet and Chase Farm Hospitals NHS... and other collaborators

Unknown

Role of Cardiac CT in Rapid Access Chest Pain Clinics (RADICAL) (RADICAL)

Coronary Artery Disease

United Kingdom
Relation Therapeutics
Barts & The London NHS Trust; Royal Free Hospital NHS Foundation Trust; Chelsea... and other collaborators

Recruiting

OSTEOMICS: Identifying Regulators of Bone Homeostasis (OSTEOMICS)

Osteoarthritis | Bone Diseases | Osteoporosis | Bone Marrow Disease | Bone Fracture

United Kingdom
Royal United Hospitals Bath NHS Foundation Trust
University of Oxford; Biotronik SE & Co. KG; University of Bath; RUHX (Official...

Recruiting

Super-Rehab: a Novel Approach to Reverse Atrial Fibrillation (SuRe-AF)

Atrial Fibrillation | Overweight and Obesity

United Kingdom
Charite University, Berlin, Germany
Freie Universität, Institute of Biology/Genetic, Berlin, Germany; Karl-Franzens-Universität...

Completed

Polyamine-enriched Diet in Elderly Individuals With Subjective Cognitive Decline (SmartAge)

Subjective Cognitive Decline (SCD)

Germany
Charite University, Berlin, Germany
Freie Universität Berlin, Institute of Biology/Genetic, Berlin,Germany; Karl-Franzens-Universität...

Completed

Polyamine-enriched Diet in Healthy Older Adults With Subjective Cognitive Decline (preSmartAge)

Subjective Cognitive Decline

Germany
University of Manchester
Northern Care Alliance NHS Foundation Trust; Royal Free Hospital NHS Foundation... and other collaborators

Enrolling by invitation

Early Diagnosis of SSc in the General Rheumatology Clinic - Pilot

Systemic Sclerosis | Raynaud Phenomenon

United Kingdom
British Cardiac Research Trust
Lund University; Royal Free Hospital NHS Foundation Trust; London North West... and other collaborators

Unknown

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects (PROCEED)

Coronary Artery Disease | Type 2 Diabetes

United Kingdom
Innersight Labs Ltd
King's College London; Guy's and St Thomas' NHS Foundation Trust; Sheffield Teaching... and other collaborators

Not yet recruiting

Virtual 3D Modelling for Improved Surgical Planning of Robotic-assisted Partial Nephrectomy (VISP)

Kidney Cancer
Queen Mary University of London
King's College London; University College London Hospitals; Barts & The London... and other collaborators

Recruiting

Mechanism of Chronic Pain in Patients With IBD

Inflammatory Bowel Diseases

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Completed

A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest (ARREST)

Out-Of-Hospital Cardiac Arrest

United Kingdom
University Hospital Birmingham NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust; Cambridge University Hospitals... and other collaborators

Active, not recruiting

Arrhythmia Burden, Risk of Sudden Cardiac Death and Stroke in Patients With Fabry Disease (RaILRoAD)

Fabry Disease

United Kingdom, Australia
Barts & The London NHS Trust
King's College London; Cambridge University Hospitals NHS Foundation Trust; Medical... and other collaborators

Completed

Stromal TARgeting for PAncreatic Cancer (STAR_PAC) (STAR_PAC)

Pancreatic Adenocarcinoma

United Kingdom
Medical University of Vienna
Medical University of South Carolina; IRCCS Azienda Ospedaliero-Universitaria... and other collaborators

Recruiting

Aortic Stenosis and Cardiac Amyloidosis

Aortic Stenosis | Cardiac Amyloidosis

Austria, United Kingdom
Queen Mary University of London
Guy's and St Thomas' NHS Foundation Trust; Barts & The London NHS Trust; Royal... and other collaborators

Active, not recruiting

Implementing Long-Acting Novel Antiretrovirals (ILANA)

Human Immunodeficiency Viruses

United Kingdom
NHS Greater Glasgow and Clyde
King's College London; University of Oxford; Royal Free Hospital NHS Foundation... and other collaborators

Completed

Precision Medicine With Zibotentan in Microvascular Angina (PRIZE)

Microvascular Angina

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust and other collaborators

Recruiting

The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment (BARCODE2)

Hormone Refractory Prostate Cancer

United Kingdom

Clinical Trials Sponsored by Royal Free Charity

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