Clinical Trials Sponsored by SignaTope GmbH, Germany

Total 259 results

Medical University of Vienna
Merck Serono GmbH, Germany

Active, not recruiting

Metformin Therapy in Non-diabetic AAA Patients (MetAAA)

Abdominal Aortic Aneurysm

Austria
Fresenius Kabi SwissBioSim GmbH
Merck KGaA, Darmstadt, Germany

Completed

MSB11022 in Moderate to Severe Chronic Plaque Psoriasis (AURIEL-PsO)

Psoriasis | Moderate to Severe Plaque Psoriasis | Plaque Type Psoriasis

United States, Canada, Czechia, Hungary, Russian Federation, Bulgaria, Mexico, United Kingdom, Poland, Germany, Estonia, France
University of Ulm
Ravensburger Spieleverlag GmbH (RSV), Germany

Completed

The Effect of Solving Jigsaw Puzzles on Visuospatial Cognition in Older Adults: Jigsaw Puzzles As Cognitive Enrichment (PACE)

Cognitive Impairment

Germany
LEO Pharma
LEO Pharma GmbH, Neu-Isenburg, Germany

Completed

Efficacy, Tolerability and Handling of Daivobet® Gel in Patients With Psoriasis Vulgaris

Psoriasis Vulgaris

Germany
University Hospital Muenster
Deutsche Krebshilfe e.V., Bonn (Germany); photonamic GmbH & Co. KG; medac GmbH; LifePhotonic GmbH

Recruiting

Stereotactical Photodynamic Therapy With 5-aminolevulinic Acid (Gliolan®) in Recurrent Glioblastoma (NOA11)

Glioblastoma Multiforme, Adult

Germany
MEDA Pharma GmbH & Co. KG
Accovion GmbH; Siro Clinpharm Germany GmbH (until June 2013)

Completed

Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2) (LEIDA 2)

Actinic Keratosis

Austria, Germany
German Society for Pediatric Oncology and Hematology...
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

Nivolumab in Children and Adults With Nasopharyngeal Carcinoma (NPC-Nivo)

Nasopharyngeal Carcinoma | Nasopharyngeal Cancer | Nasopharynx Cancer | Nasopharyngeal Neoplasms

Germany
Miltenyi Biomedicine GmbH
DLR German Aerospace Center

Terminated

MB-CART20.1 Melanoma

Melanoma (Skin)

Germany
German Institute of Human Nutrition
Beneo GmbH

Completed

Isomaltulose VS Sucrose - Postprandial Effect on Incretin Profile and Second Meal Effect

Diabetes Mellitus, Type 2 | Metabolic Syndrome

Germany
Charite University, Berlin, Germany
The Federal Office for Radiation Protection, Germany; Seibersdorf Labor GmbH

Completed

Terrestrial Trunked Radio (TETRA) and Cognitive Functions in Healthy Subjects (TETRA)

Healthy

Germany
HiPP GmbH & Co. Vertrieb KG
Charite University, Berlin, Germany

Completed

Atopic Dermatitis in Atopy Predisposed Infants (ADAPI)

Dermatitis, Atopic

Germany
HiPP GmbH & Co. Vertrieb KG
Charite University, Berlin, Germany

Completed

Low-protein Infant Formula With Partial or Extensive Proteinhydrolysate 4 Year Follow-up (HippHA)

Disturbance of Growth

Germany, Austria, Serbia
Charite University, Berlin, Germany
Cassella-med GmbH & Co. KG

Completed

Efficacy of Euminz® for Tension-Type Headache (CAS/B/016611)

Episodic Tension-Type Headache

Germany
Free University of Bozen-Bolzano
Evonik Operations GmbH, Germany

Completed

Use of a Selected Mixture of Probiotic Strains for Degrading Gluten During Digestion

Probiotics

Italy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
Merck Healthcare Germany GmbH, an affiliate of Merck KGaA, Darmstadt, Germany

Active, not recruiting

An Observational Study to Evaluate the Efficacy and Safety of Avelumab + Axitinib Combination in Participants With aRCC (AVION)

Carcinoma, Renal Cell

Germany, Greece, Belgium, Russian Federation
University Hospital Tuebingen
German Research Foundation; CenTrial GmbH

Completed

Safety and Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus

Tinnitus

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Medizinische Hochschule Hannover, Germany, Prof. Dr. Arndt Vogel; MSD Sharp...

Recruiting

Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract Cancer (TRAP-BTC)

Biliary Tract Cancer | HER2 Gene Mutation

Germany
Charite University, Berlin, Germany
Boston Scientific Corporation; IKKF GmbH; IHF Ludwigshafen; Cordis Medizinische...

Completed

Economic Evaluation German Drug-Eluting Stent Registry

Coronary Heart Disease
Mylan Inc.
Mylan Österreich GmbH; Mylan Germany GmbH; Mylan Healthcare Sp. z o.o.

Completed

Observation of the Effects of Guideline-driven Lifestyle Interventions, Including Use of a Red-yeast Based Nutraceutical

Hypercholesterolemia

Germany, Austria
The Federal Office for Radiation Protection, Germany
Seibersdorf Labor GmbH

Completed

RF-EMF Effects on the CNS in Elderly Men (EMF60+males)

Non-Ionizing Radiation

Germany
Universitätsklinikum Hamburg-Eppendorf
KARL STORZ GmbH & Co. KG, Tuttlingen, Germany

Completed

Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall Stones (SAC)

Cholestasis | Choledocholithiasis | Common Bile Duct Neoplasms

Germany
Johann Wolfgang Goethe University Hospital
Pfrimmer Nutricia GmbH, Erlangen , Germany

Completed

Peroral Supplemental Nutrition in End-stage Renal Disease With and Without HIV Comorbidity

End-Stage Renal Disease

Germany
The Federal Office for Radiation Protection, Germany
Seibersdorf Labor GmbH

Completed

Radiofrequency Electromagnetic Field (RF-EMF) Effects on Brain Activity During Sleep and Waking in Healthy Elderly Women (EMF60+women)

Nervous System Effects

Germany
Charite University, Berlin, Germany
Pro-Implant Foundation; Ceram Tec GmbH

Unknown

Biofilm Investigation on Bearing Components of Explanted Hip Joint Prosthesis

Total Hip Replacement | Biofilm | Sonication

Germany
University Hospital, Saarland
Baxter Healthcare Corporation; Pharmacia GmbH, Erlangen, Germany

Completed

Tranexamic Acid and Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) (TAHHT)

Hereditary Hemorrhagic Telangiectasia

Germany
University Hospital Muenster
Nichols Institute Diagnostika GmbH, Bad Vilbel, Germany

Completed

Clinical Evaluation of a New Highly Sensitive Thyroglobulin Assay in Differentiated Thyroid Carcinoma

Thyroid Neoplasms

Germany
Institut für Klinische Krebsforschung IKF GmbH...
AstraZeneca; Universitätsklinikum Köln, Germany; Universitätsklinikum Düsseldorf...

Not yet recruiting

Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

Extrahepatic Cholangiocarcinoma | Unresectable Perihilar or Ductal CCA

Germany
AIO-Studien-gGmbH
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

D,L-MEthadone and mFOLFOX6 in Treatment of Advanced Colorectal Cancer (MEFOX)

Chemo-refractory Colorectal Carcinoma

Germany
Charite University, Berlin, Germany
Leipzig Heart Science gGmbH

Recruiting

Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation (PROFID EHRA)

Myocardial Infarction | Sudden Cardiac Death

Germany, Czechia, Austria
AIO-Studien-gGmbH
Bayer; Charite University, Berlin, Germany

Terminated

Rivaroxaban in the Treatment of Venous Thromboembolism (VTE) in Cancer Patients

Cancer | Venous Thromboembolism

Germany
Dominik Paul Modest
German Research Foundation; Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418)

Colorectal Cancer

Germany
Biotest
Accovion GmbH; ICON plc; SYNLAB Analytics and Services Germany GmbH; Phoenix Clinical... and other collaborators

Completed

Pharmacokinetic, Efficacy and Safety of BT524 in Patients With Congenital Fibrinogen Deficiency

Congenital Afibrinogenemia | Congenital Hypofibrinogenemia

Bulgaria, Egypt, Germany, Lebanon, Tunisia
West German Center of Diabetes and Health
Tchibo GmbH

Completed

Health Effects of Coffee Consumption (DüsselKaffee)

Overweight

Germany
German Breast Group
Pfizer; AMS Advanced Medical Services GmbH

Recruiting

A Randomized, Open-label, Multi-center Phase IV Study Evaluating Palbociclib Plus Endocrine Treatment Versus a Chemotherapy-based Treatment Strategy in Patients With Hormone Receptor Positive / HER2 Negative Breast Cancer in a Real World Setting (GBG 93 - PADMA Study). (PADMA)

Metastatic Breast Cancer

Germany
West German Center of Diabetes and Health
Bionatural GmbH

Completed

Foot Cream for the Care of Dry and Cracked Skin

Diabetes Mellitus

Germany
University of Erlangen-Nürnberg Medical School
Pfrimmer Nutricia GmbH, Erlangen , Germany

Completed

Effects of Oral Nutritional Supplements in Nursing Home Residents

Nursing Home Residents | Malnutrition or Risk of Malnutrition

Germany
Ludwig-Maximilians - University of Munich
Merck KGaA, Darmstadt, Germany; ClinAssess GmbH

Active, not recruiting

FOLFIRI + Cetuximab + Avelumab RAS Wild-type CRC

Treatment Related Cancer

Germany
Anavex Life Sciences Corp.
Anavex Australia Pty Ltd.; Anavex Germany GmbH

Completed

ANAVEX2-73 Study in Pediatric Patients With Rett Syndrome (EXCELLENCE)

Rett Syndrome

Canada, Australia, United Kingdom
Charite University, Berlin, Germany
MediTECH Electronic GmbH; AudioProfiling, Dr. Joerg Langner

Unknown

ADHD - Voice Analysis, Vocal Acoustic Biomarkers in Attention Deficit Hyperactivity Disorder (ADHD)

Attention-Deficit/Hyperactivity Disorder

Germany
University Hospital Muenster
New Health Sciences, Inc.; Rubel GmbH, Heiligenhaus, Germany

Completed

Continuous Positive Airway Pressure Ventilation After Acute Ischemic Stroke

Brain Infarction

Germany
Charite University, Berlin, Germany
Bristol-Myers Squibb; Pierre Fabre Pharma GmbH

Unknown

Study for Patients With Non Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

Germany
Christoph Königs
Roche Pharma AG; Chugai Pharma Germany GmbH

Recruiting

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab (NAVIGATE)

Severe Hemophilia A | Severe Hemophilia A With Inhibitor | Severe Hemophilia A Without Inhibitor

Germany
Anavex Life Sciences Corp.
Anavex Australia Pty Ltd.; Anavex Germany GmbH

Active, not recruiting

OLE of Phase 2b/3 Study ANAVEX2-73-AD-004 (ATTENTION-AD)

Alzheimer Disease

Australia, Canada, Germany, Netherlands, United Kingdom
Anavex Life Sciences Corp.
Anavex Australia Pty Ltd.; Anavex Germany GmbH

Completed

OLE Study for Patients With Parkinson's Disease With Dementia Enrolled in Study ANAVEX2-73-PDD-001

Parkinson Disease Dementia

Spain, Australia
Merck KGaA, Darmstadt, Germany
Gesellschaft für Therapieforschung mbH

Completed

An Observational Study Evaluating Therapy Optimisation Using High-frequency and High-dosage Administration of Interferon-beta (Rebif®) in Multiple Sclerosis (MS) Patients

Relapsing-Remitting Multiple Sclerosis
Merck KGaA, Darmstadt, Germany
Gesellschaft für Therapieforschung mbH

Completed

An Observational Study to Document the Effectiveness and Compatibility of Rebif 44 or 22 µg in the Therapy of the Chronic Multiple Sclerosis

Multiple Sclerosis

Germany
Merck KGaA, Darmstadt, Germany
Merck Gesellschaft mbH, Austria

Completed

Bisoprolol in Hypertension: Effect on Concomitant Elevated Heart Rate

Hypertension

Austria
Merck KGaA, Darmstadt, Germany
Gesellschaft für Therapieforschung mbH

Completed

A Phase IV Study of Rebif ® 44mcg Administered Three Times Per Week by Subcutaneous Injection Compared With no Treatment in the Therapy of Relapsing Multiple Sclerosis After Mitoxantrone (REMAIN)

Multiple Sclerosis, Relapsing-Remitting
Merck KGaA, Darmstadt, Germany
Merck Gesellschaft mbH, Austria

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Austria (ECOS AUT)

Growth Disorders

Austria
Johannes Gutenberg University Mainz
Sanofi; Bayer; Boehringer Ingelheim; German Federal Ministry of Education and Research and other collaborators

Completed

Evaluation of Oral Anticoagulation With Vitamin K Antagonists - The thrombEVAL Study Programme (thrombEVAL)

Atrial Fibrillation | Venous Thromboembolism | Anticoagulant Antagonists, Vitamin K and Other Coagulants Causing Adverse Effects in Therapeutic Use

Germany

Clinical Trials Sponsored by SignaTope GmbH, Germany

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mozambique

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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