Clinical Trials Sponsored by Spectros Corporation

Total 6704 results

Spectrum Health Hospitals

Completed

The Bladder Instillation Comparison Study (BIC)

Urinary Bladder Neoplasms

United States
Spectrum Health Hospitals

Completed

The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.

Postoperative Pain

United States
Spectrum Pharmaceuticals, Inc

Terminated

Pralatrexate vs Observation Following CHOP-based Chemotherapy in Undiagnosed Peripheral T-cell Lymphoma Patients

Peripheral T-cell Lymphoma

Belgium, Spain, United States, Australia, France, Israel, Canada, United Kingdom, New Zealand, Italy, Ireland, Poland, Puerto Rico
Spectrum Pharmaceuticals, Inc

Completed

The Safety and Efficacy of Ozarelix to Treat Men With Lower Urinary Tract Symptoms Due to Enlargement of the Prostate

Benign Prostatic Hypertrophy

United States
Spectrum Pharmaceuticals, Inc

Terminated

Phase II Study of SPI-1620 in Combination With Docetaxel as a Second-Line to Treat Biliary Cancer

Biliary Cancer

United States
Spectrum Pharmaceuticals, Inc

Terminated

Rituximab or Zevalin - Efficacy Trial of Therapeutic Alternatives (RoZetta)

Follicular Lymphoma

United States
Spectrum Pharmaceuticals, Inc

Terminated

A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL

Acute Lymphoblastic Leukemia (ALL)

United States
Spectrum Pharmaceuticals, Inc

Completed

Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

Metastatic Cancer

France, United States, Canada, Belgium, Italy, Australia, United Kingdom, Germany, Hungary
Spectrum Pharmaceuticals, Inc

Completed

Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)

Bladder Cancer

United States
Spectrum Pharmaceuticals, Inc

Completed

Pharmacokinetics of SPI-2012 (Eflapegrastim) in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide (TC) Chemotherapy

Breast Cancer | Pharmacokinetics

United States
Spectrum Health Hospitals

Completed

Phase I: Melphalan, Bendamustine and Carfilzomib for Autologous Transplant in Multiple Myeloma

Multiple Myeloma

United States
Spectrum Health Hospitals

Completed

TAP Versus Thoracic Epidural in Major Abdominal Resections

Surgery | Malignant Neoplasm of Abdomen

United States
Spectrum Health Hospitals

Withdrawn

Arthroscopic Assisted Open Reduction Internal Fixation Versus Open Reduction Internal Fixation in Ankle Fractures

Ankle Fractures

United States
Medisch Spectrum Twente

Unknown

Serial Hybrid Atrial Fibrillation Ablation (SHAFT)

Atrial Fibrillation

Netherlands
Spectrum Pharmaceuticals, Inc

Withdrawn

A Study to Assess the Safety and Preliminary Efficacy of PT-523 in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Carcinoma

United States, Russian Federation
Spectrum Pharmaceuticals, Inc

Withdrawn

A Study to Evaluate PT-523 in Patients With Refractory Leukemia

Leukemia

United States
Spectrum Pharmaceuticals, Inc

Completed

Phase II Trial of EOquin in High-risk Superficial Bladder Cancer

Bladder Neoplasms

Netherlands
Spectrum Pharmaceuticals, Inc

Completed

Elsamitrucin (SPI 28090) for Relapsed or Refractory Non-Hodgkin's Lymphoma

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

United States
Spectrum Health - Lakeland

Recruiting

Cooling Helmets to Decrease Concussion Symptoms (ColdCon)

TBI (Traumatic Brain Injury) | Concussion, Mild

United States
Spectrum Health - Lakeland

Recruiting

Platelet Reactivity With Fentanyl, Morphine, or no Narcotic

Platelet Reactivity | Fentanyl

United States
Spectrum Health Hospitals

Recruiting

Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function/Earlier Discharge (RICART)

Colorectal Disorders

United States
Spectrum Pharmaceuticals, Inc

Active, not recruiting

Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer

Breast Cancer | Neutropenia

United States
Spectrum Pharmaceuticals, Inc

Terminated

Phase 2 Study of Poziotinib in Participants With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation

NSCLC

United States, Canada, Netherlands, Belgium, Israel, Spain, France, Italy
Spectrum Health Hospitals

Completed

Prophylactic Maze to Prevent Atrial Fibrillation in Adult Cardiac Surgery (PREVENT-AF)

Coronary Artery Disease

United States
Spectrum Health Hospitals

Completed

Suprapatellar Nailing of Tibial Shaft Fractures

Broken Leg
Spectrum Health - Lakeland

Completed

Troponin Leaks in Emergency Department Patients Presenting With Supraventricular Tachycardia (SVT)

Supraventricular Tachycardia
Spectrum Pharmaceuticals, Inc

Completed

Phase 2 Study of SPI-2012 or Pegfilgrastim for the Management of Neutropenia in Participants With Breast Cancer

Neutropenia

Australia, Poland, United States, Hungary, Israel, Georgia
Spectrum Pharmaceuticals, Inc

Completed

SPI-2012 vs Pegfilgrastim in the Management of Neutropenia in Participants With Breast Cancer With Docetaxel and Cyclophosphamide (ADVANCE) (ADVANCE)

Breast Cancer | Neutropenia

United States, Canada, Korea, Republic of
Spectrum Pharmaceuticals, Inc

Completed

SPI-2012 vs Pegfilgrastim in Management of Neutropenia in Breast Cancer Participants With Docetaxel and Cyclophosphamide

Breast Cancer | Neutropenia

United States, Canada, India, Hungary, Korea, Republic of, Poland
Spectrum Pharmaceuticals, Inc

Terminated

Study of Zevalin Versus Observation in Participants at Least 60 Years Old With Newly Diagnosed Diffuse Large B-cell Lymphoma in Positron Emission Tomography (PET)-Negative Complete Remission After Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) or R-CHOP-like Therapy

Diffuse Large B-cell Lymphoma | Follicle Center Lymphoma

United States, France, United Kingdom, Ireland, Israel, Belgium, Spain, Netherlands, Australia, Puerto Rico, Canada, Italy, Austria
Spectrum Pharmaceuticals, Inc

Terminated

A Study of Intravesical Apaziquone as a Surgical Adjuvant in Participant Undergoing Transurethral Resection Bladder Tumor (TURBT)

Bladder Cancer

United States
Spectrum Pharmaceuticals, Inc

Terminated

Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme(GBM)

Glioblastoma Multiforme

United States, India
Spectrum Pharmaceuticals, Inc

Terminated

Phase 2 Study of Zevalin Versus Zevalin and Motexafin Gadolinium in Patients With Rituximab-Refractory Low-grade or Follicular B-cell Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United States
Spectrum Pharmaceuticals, Inc

Completed

A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants

Healthy

United States
Spectrum Pharmaceuticals, Inc

Terminated

A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib

Solid Tumor

United States
Spectrum Pharmaceuticals, Inc

Terminated

A Study of Poziotinib in Combination With T-DM1 in HER2-Positive Breast Cancer

Breast Cancer

United States
Spectrum Pharmaceuticals, Inc

Completed

Study of the Absorption, Metabolism, and Excretion Following a Single Dose of [14C]-Poziotinib in Healthy Male Subjects

Healthy

United States
Spectrum Pharmaceuticals, Inc

Completed

Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumors

Small Cell Lung Cancer | Ovarian Cancer | Solid Tumors

United States
Spectrum Pharmaceuticals, Inc

Completed

Safety, Tolerability and Systemic Absorption of Menadione Topical Lotion for Epidermal-Growth-Factor-Receptor (EGFR) Inhibitor-Associated Rash

EGFR Inhibitor-associated Rash

United States, Canada
Spectrum Health - Lakeland

Unknown

Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock

Septic Shock

United States
Medisch Spectrum Twente

Unknown

Extended Rhythm SCreening for AtRial Fibrillation in Cryptogenic Stroke Patients (SCARF)

Stroke | Atrial Fibrillation

Netherlands
Spectrum Pharmaceuticals, Inc

Completed

Study of Vinorelbine Liposomes Injection for Advanced Solid Tumors, Non-Hodgkin's Lymphoma or Hodgkin's Disease

Non-Hodgkins Lymphoma | Tumors | Hodgkins Disease

United States, Canada
Medisch Spectrum Twente

Unknown

Resuscitation Strategies in Septic Shock (ReSSeS)

Septic Shock | Critically Ill

Netherlands
Spectrum Health Hospitals

Unknown

Vancomycin Prophylaxis in Recurrent Clostridium Difficile Infection

Clostridium Difficile Infection

United States
Spectrum Pharmaceuticals, Inc

Completed

Study to Assess the Safety and the Phosphate Binding Capacity of Renazorb (SPI-014)

Safety | Phosphate Binding Capacity

United States
Spectrum Pharmaceuticals, Inc

Completed

A Phase I, Open-label, Ascending Dose Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the Endothelin B Agonist, SPI-1620, in Patients With Recurrent or Progressive Carcinoma

Carcinoma

United States
Spectrum Pharmaceuticals, Inc

Terminated

Study of RH-1 in Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma | Advanced Solid Tumors

United States
Spectrum Pharmaceuticals, Inc

Withdrawn

Chemotherapy and Radiation Therapy With or Without Efaproxiral in Treating Patients With Stage III Non-Small Cell Lung Cancer

Lung Cancer

United States, Canada, Belgium, Israel
Medisch Spectrum Twente

Unknown

Ultrasound Guided Needling Versus Ultrasound Guided Corticosteroid Injection Alone, a Randomized Controlled Trial. (BARB-01)

Calcific Tendinitis

Netherlands
Spectral Diagnostics (US) Inc.

No longer available

Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19

Septic Shock | Endotoxemia | COVID | Corona Virus Infection | Sepsis, Severe

United States

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