Clinical Trials Sponsored by Vectura, Inc.

Total 35860 results

GlaxoSmithKline
Medicines for Malaria Venture

Completed

G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)

Malaria

Thailand
Aventura Hospital and Medical Center

Unknown

HFNC Versus Conventional Nasal Cannula in Oxygen Performance in Patients Receiving Colonoscopy Under IV Sedation (HFNC)

Desaturation of Blood

United States
Sanofi
Medicines for Malaria Venture

Terminated

To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria (FALCI)

Plasmodium Falciparum Infection

Benin, Burkina Faso, Gabon, Kenya, Mozambique, Uganda, Vietnam
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Vietnam, Colombia
Daisy Pharma Opioid Venture, LLC

Unknown

Dronabinol Opioid Sparing Evaluation (DOSE) Trial

Chronic Pain

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects

Malaria

United Kingdom
Sanofi
Medicines for Malaria Venture

Completed

Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire

Malaria

Côte D'Ivoire
São Paulo State University
Andréa Maria Cordeiro Ventura

Active, not recruiting

Pediatric Ventilation Weaning (PROVENTUS)

Respiration, Artificial | Ventilator Weaning

Brazil
H. Lee Moffitt Cancer Center and Research Institute
Secura Bio, Inc.

Active, not recruiting

Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

Hodgkin Lymphoma | Non Hodgkin Lymphoma | Myeloma | Lymphocytic Leukemia

United States
John Kirkwood
Bristol-Myers Squibb; Secura Bio, Inc.

Recruiting

Duvelisib in Combination With Nivolumab in Patients With Advanced Unresectable Melanoma

Unresectable Melanoma

United States
Lund University
Vinnova; Öste Venture AB

Completed

Dietary Fibre and Metabolic Benefits

Glucose Tolerance

Sweden
GlaxoSmithKline
Parexel; Medicines for Malaria Venture

Completed

A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution

Malaria, Vivax

United States
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) Tablets

Malaria

United Kingdom
Gamida Cell -Teva Joint Venture Ltd.

Completed

Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy (ExCell)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Non-Hodgkin's Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancies | Hodgkin's Disease | Lymphoid Leukemia

United States, Israel, Hungary, Italy, Spain
Medicines for Malaria Venture
Quotient Clinical

Completed

Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)

Malaria

United Kingdom
Medicines for Malaria Venture
Mahidol University

Completed

Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection

Malaria, Falciparum | Malaria, Vivax
Treague Ltd
Medicines for Malaria Venture

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of AD 452 [(+)-Mefloquine] Compared With Racemic Mefloquine

Healthy Subjects

United Kingdom
David Brunk
Colorado Cardiac Alliance

Recruiting

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG) (AFCOG)

Cognitive Impairment | Atrial Fibrillation | Cognitive Change | Executive Dysfunction | Cognitive Symptom | Cognitive Impairment, Mild

United States
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Atoguanil BA Study

Bioavailability

United Kingdom
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria

Malaria

Indonesia, Cambodia, India, Thailand
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients

Falciparum Malaria

Cambodia, India, Thailand, Burkina Faso, Côte D'Ivoire, Tanzania, Vietnam
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)

Malaria

United Kingdom
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

A Study to Evaluate the Pharmacokinetics of Oral Formulations of MMV390048 Administered Fasted to Healthy Volunteers

Malaria

United Kingdom
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

A FIH Study to Investigate the Safety, Tolerability and PK of P218

Malaria

United Kingdom
Novartis Pharmaceuticals
Medicine for Malaria Venture

Terminated

Effectiveness of KAE609 in Reducing Asexual & Sexual Blood-stage P.Falciparum Infection & Infectivity to Mosquitos

Plasmodium Falciparum Malaria

Australia
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kg

Acute Uncomplicated Falciparum Malaria

Burkina Faso, Benin, Congo, Nigeria, Togo
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz

Malaria

United Kingdom
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Malaria

United Kingdom
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients

Malaria

Burkina Faso, Congo, The Democratic Republic of the, Kenya, Mali, Mozambique, Philippines, Côte D'Ivoire, Gabon
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Bioequivalence of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet (SP-C-009-07)

Malaria

Switzerland
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted State

Malaria

United Kingdom
Medicines for Malaria Venture
Cross Research S.A.

Completed

Safety Tolerability & Pharmacokinetics of Co-administered Single Doses of OZ439 & Piperaquine to Healthy Subjects

Healthy

Switzerland
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine/Artesunate -Ritonavir Drug Drug Interaction Study

Malaria

Switzerland
Centura Health
University of Colorado, Colorado Springs

Not yet recruiting

Muscle and Body Temperature Responses During Uphill and Downhill Running

Exercise | Blood Pressure | Body Temperature Changes
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole

Malaria

United Kingdom
Centura Health
NeuFit - Neurological Fitness and Education

Completed

Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS

Multiple Sclerosis

United States
Novartis Pharmaceuticals
Medicines for Malaria Venture

Completed

Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria

Acute Uncomplicated Plasmodium Falciparum Malaria

Thailand, Gabon, Mali, Uganda, Burkina Faso, India, Kenya, Mozambique, Vietnam
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Human Mass Balance Study of Pyronaridine

Malaria

Switzerland
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Terminated

Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria

Malaria

Korea, Republic of
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients

Malaria

Congo, The Democratic Republic of the, Gambia, Ghana, Indonesia, Kenya, Mali, Mozambique, Philippines, Senegal
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers

Malaria

United Kingdom
4YouandMe
Cambridge Cognition Ltd; Sema4; Evidation Health; Vector Institute of Artificial... and other collaborators

Completed

Better Understanding the Metamorphosis of Pregnancy (BUMP) (BUMP)

Pregnancy Related | Wearables | Pregnancy Early

United States
University of California, Berkeley
Tigray Regional Health Bureau; Venture Strategies for Health and Development; Venture Strategies innovations

Completed

Community Based Distribution of Injectable Contraceptives in Tigray, Ethiopia (CBDDMPA)

Contraception | Family Planning | Task Shifting | Community Based Distribution | DMPA

Ethiopia
IND Diagnostic Inc.

Unknown

Evaluation of the IND One Step Strep A Rapid Test vs. Culture

Strep Throat

United States
Medicines for Malaria Venture
Q-Pharm Pty Limited

Terminated

MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants

Malaria, Falciparum

Australia
Medicines for Malaria Venture
University of Cape Town

Completed

Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers

Malaria

South Africa
Medicines for Malaria Venture
University of Cape Town

Terminated

Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy Volunteers

Malaria

South Africa
Medicines for Malaria Venture
Asociacion Civil Selva Amazonica

Completed

DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or Vivax

Plasmodium Falciparum Malaria | Plasmodium Vivax Malaria

Peru
sigma-tau i.f.r. S.p.A.
Medicines for Malaria Venture

Completed

Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteers

Malaria, Falciparum

France

Clinical Trials Sponsored by Vectura, Inc.

Sponsors and Collaborators

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Drug Interventions

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CROs in Mauritius

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Rare Diseases

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