Search clinical trials for: Hemoglobin SC disease

Total 428384 results

Sohag University

Not yet recruiting

Assessment of Cognitive Function and Quality of Life in Thalassemic Children at Sohag University Hospital

Thalassemia

Egypt
Wuhan Createrna Science and Technology Co., Ltd

Recruiting

A Study of MY008211A in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria

China
Inova Health Care Services
Pfizer

Recruiting

Assessing Physical Function in Sickle Cell Patients Taking Voxelotor

Sickle Cell Disease

United States
Duke University
American Society of Hematology

Recruiting

COVID-19 Vaccination Hesitancy in Adults With Sickle Cell Disease

Sickle Cell Disease | COVID-19 Vaccine | Vaccine Hesitancy

United States
George Washington University

Not yet recruiting

Hemoglobin Testing in Pregnant Patients (Prosp Anemia)

Post Partum Hemorrhage | Anemia of Pregnancy
Omeros Corporation

Recruiting

Safety and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria Patients With a Sub-optimal Response to Ravulizumab

Paroxysmal Nocturnal Hemoglobinuria

Germany, Greece, Switzerland, United Kingdom
Forma Therapeutics, Inc.
Novo Nordisk A/S

Recruiting

A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke

Sickle Cell Disease

Nigeria, India, Oman
Afnan Bkri

Not yet recruiting

Physiotherapy for Children With Sickle Cell Disease: A Randomized Controlled Trial (RCT)

Blood Disease
Bartın Unıversity
Abant Izzet Baysal University; Health Institutes of Turkey

Recruiting

The Effects of Topical Haemoglobin Spray in Pressure Ulcer

Wound Heal | Pressure Ulcer

Turkey
Academisch Medisch Centrum - Universiteit van Amsterdam...
Leiden University Medical Center

Recruiting

Do Alemtuzumab Levels Predict T Cell Chimerism After MSD SCT for SCD? (PREDICT)

Sickle Cell Disease

Netherlands
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

Anemia

India
Omeros Corporation

Recruiting

Study of the Safety and Efficacy of OMS906 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

Ukraine
ADARx Pharmaceuticals, Inc.
ADARx Australia Pty Ltd

Recruiting

Safety, Tolerability, PK and PD of ADX-038 in HV and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Australia
Afimmune

Recruiting

Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease

Sickle Cell Disease

United States
Centre Hospitalier Universitaire Saint Pierre

Recruiting

Clonidine With Morphine in Patient Controlled Analgesia Pump in Vaso-Occlusive Crisis in Sickle Cell Disease Patient

Sickle Cell Disease | Vaso-occlusive Pain Episode in Sickle Cell Disease

Belgium
Ahmadu Bello University Teaching Hospital
Cyprus Institute of Neurology and Genetics

Not yet recruiting

Genetic and Haematological Modifiers of SCD Severity in Kaduna State, Northern Nigeria (SCA)

Sickle Cell Disease
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Association of Apical Periodontitis With Systemic Level of Inflammatory Markers : A Longitudinal Intervention Study

Diabetes Mellitus, Type 2 | Apical Periodontitis

India
Cyprus Institute of Neurology and Genetics

Recruiting

Study of the Role of Genetic Modifiers in Hemoglobinopathies (INHERENT)

Sickle Cell Disease | Hemoglobinopathies | Thalassemia Alpha | Thalassemia, Beta

United States, Denmark, Spain, Belgium, Portugal, Congo, The Democratic Republic of the, Greece, Argentina, Brunei Darussalam, Cyprus, Israel, Italy, Nigeria, Malaysia, Angola, Pakistan
Chinese University of Hong Kong

Recruiting

In-utero Hematopoietic Stem Cell Transplantation for the Treatment of Fetuses With Bart's Hydrops Fetalis Syndrome

Haemoglobin Barts Hydrops

Hong Kong
Shandong Qilu Stem Cells Engineering Co., Ltd.
Second Affiliated Hospital of Zhengzhou University; The Second Affiliated Hospital... and other collaborators

Recruiting

Clinical Study of UCB Combined With UC-MSCs in the Treatment of Bone Marrow Failure Disorders

Bone Marrow Failure Disorders

China
Centre Hospitalier Universitaire de Pointe-a-Pitre
Direction Générale de l'Offre de Soins

Recruiting

Lipid Balance in Adult Sickle Cell Patients (HDL2)

Dyslipidemia | Sickle Cell Disease | Complication

France
Assiut University

Not yet recruiting

NAC Effect on Iron Overload and Blood Transfusion in β-thalassemia Major

Thalassemia Major
Swedish Orphan Biovitrum

Recruiting

A Real World Effectiveness Study of Pegcetacoplan in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) (COMPLETE)

Paroxysmal Nocturnal Hemoglobinuria

Spain
Aplastic Anemia and MDS International Foundation
National Organization for Rare Disorders

Recruiting

Global PNH Patient Registry

Paroxysmal Nocturnal Hemoglobinuria

United States
Regeneron Pharmaceuticals

Recruiting

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works. (ACCESS-EXT)

Paroxysmal Nocturnal Hemoglobinuria

Taiwan, Korea, Republic of, Turkey, Spain, Thailand, Singapore, Japan, Canada, Malaysia, Poland, Italy, Romania
University Hospital, Basel, Switzerland
SolidarMed; Swiss Agency for Development and Cooperation (SDC); World Diabetes...

Recruiting

Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho (ComBaCaL T2D)

Type 2 Diabetes Mellitus (T2D)

Lesotho, Switzerland
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Soliris-Treated Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

PNH - Paroxysmal Nocturnal Hemoglobinuria
University of Pennsylvania

Recruiting

Effects of the Contraceptive Implant in Women With Sickle Cell Disease (SCD CURE)

Sickle Cell Disease

United States
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Bristol-Myers Squibb

Recruiting

A Study to Determine the Efficacy and Safety of Luspatercept in Adult and Adolescent Participants With Alpha (α)-Thalassemia

Anemia

Thailand, China, Canada, Turkey, Greece, Taiwan, Italy, Hong Kong
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Adult PNH Patients With Inadequate Response to Soliris

Paroxysmal Nocturnal Hemoglobinuria
NovelMed Therapeutics

Not yet recruiting

Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

Paroxysmal Nocturnal Hemoglobinuria
Sanguine Biosciences

Recruiting

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Heart Diseases | Stroke | Lymphoma | Multiple Sclerosis | Kidney Diseases | Diabetes | Leukemia | Age-Related Macular Degeneration | Cancer | Arthritis | Schizophrenia | Thyroid Diseases | Parkinson Disease | Hepatitis | Vasculitis | Psoriasis | Asthma | Amyloidosis | Fibromyalgia | Graves Disease | Alzheimer Disease | Celiac Disease | Cirr... and other conditions

United States
College Osteopathique de Provence Aix-Marseille
University Hospital, Marseille

Recruiting

Osteopathic Manipulation in the Management of Pain Associated With Sickel Cell Disease (OSTEODREP)

Sickle Cell Disease

France
Pfizer
Pfizer

Recruiting

GBT021601-022: A Study of GBT021601 in Participants With Sickle Cell Disease (SCD)

Sickle Cell Disease

United States, Nigeria
Washington University School of Medicine
Biogen; BioLineRx, Ltd.

Recruiting

Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD)

Sickle Cell Disease

United States
Hospital Clinic of Barcelona
Institut d'Investigacions Biomèdiques August Pi i Sunyer; Banc de Sang i Teixits

Recruiting

Red Blood Cells From Umbilical Cord for Transfusion of Preterm Infants

Infant, Extremely Premature | Erythrocyte Transfusion | Umbilical Cord Issue

Spain
University of Cincinnati

Not yet recruiting

Minocycline In Neurocognitive Outcomes - Sickle Cell Disease (MINO-SCD)

Cognitive Impairment | Cognitive Dysfunction | Cognitive Change | Sickle Cell Disease | Cognitive Decline | Cognitive Deficit | Neuroinflammatory Response

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)

SCD

United States
Tanta University

Recruiting

Clinical Study to Evaluate the Possible Efficacy and Safety of L- Carnitine and Sildenafil in Children Having Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity

Beta Thalassemia With Increased Tricuspid Regurgitant Jet Velocity

Egypt
Dr. Marjon H. Cnossen MD PhD
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Recruiting

Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) (BRICK)

Sickle Cell Disease | Brain Development Abnormality

Netherlands
University Hospital, Grenoble

Not yet recruiting

Nano-rheological Biomarkers for Patients With Sickle Cell Disease (SCD) Versus Control Subjects (Other Constitutional Red Blood Cell Diseases and Healthy Subjects) (DREPNANO)

Sickle Cell Disease
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Italy, Germany, Saudi Arabia
Kira Pharmacenticals (US), LLC.

Not yet recruiting

To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of KP104

Paroxysmal Nocturnal Hemoglobinuria

China
National Cancer Institute (NCI)

Recruiting

Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)

Insomnia | Sickle Cell Disease | Sickle Cell Anemia | Sleeplessness | Transient Insomnia | Nonorganic Insomnia | Chronic Insomnia

United States
Beam Therapeutics Inc.

Recruiting

BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease (BEACON)

Sickle Cell Disease

United States
Julia Xu
Carnegie Mellon University; American Society of Hematology

Recruiting

Hydroxyurea and EPO in Sickle Cell Disease (ACHiEvE-SCD)

Sickle Cell Disease | Anemia, Sickle Cell

United States, Nigeria
Assuta Ashdod Hospital

Recruiting

Use of Tranexamic Acid After Vaginal Delivery With Episiotomy a RCT Placebo Control Trail

Anemia | Episiotomy Wound | Hemoglobin | Early Postpartum Hemorrhage

Israel
Pfizer
Pfizer

Recruiting

A Phase 2/3 Study in Adult and Pediatric Participants With SCD

Sickle Cell Disease

United States, Nigeria, Kenya, Lebanon
The Hospital for Sick Children
Thalassemia Foundation of Canada

Recruiting

Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia

Thalassemia in Children

Canada

Search clinical trials for: Hemoglobin SC disease

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