Search clinical trials for: Susceptibility Genes

Total 3739 results

NHS Greater Glasgow and Clyde
University of Glasgow; Roche Diagnostics GmbH

Not yet recruiting

Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH)

Cardiomyopathies | Genetic Predisposition | Cardiomyopathy, Primary
Ascidian Therapeutics, Inc

Recruiting

Prescreening Study to Identify Potential Participants for ACDN-01 Clinical Trials

Stargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod Dystrophy

United States
Jiaxing Pharmadax Genesis Pharmaceutical Technology...

Not yet recruiting

Technetium [99mTc]-H7ND in Patients With Gastrointestinal Malignancies and Healthy Volunteers

Solid Tumor
University Hospital, Angers

Not yet recruiting

Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HD (FibroTG-HD)

Huntington Disease

France
IRCCS San Raffaele
Federico II University

Not yet recruiting

Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome (ACS GEDI)

Acute Coronary Syndrome | Genetic Predisposition | Gender

Italy
Canadian Cancer Trials Group
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes (OPTION-DDR)

Metastatic Prostate Cancer | Metastatic Castration-resistant Prostate Cancer
Enloe Health
Robert A. Winn Diversity in Clinical Trials Award Program

Not yet recruiting

A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention (GENESIS)

Solid Tumor, Adult
Hospital Universitari Vall d'Hebron Research Institute
Hospital General Universitario Gregorio Marañon; Hospital Clinic of Barcelona; Germans Trias i Pujol Hospital and other collaborators

Recruiting

Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease.

Hepatocellular Carcinoma | Portal Hypertension | Advanced Chronic Liver Disease

Spain
Selcuk University

Not yet recruiting

Chronic Suppurative Otitis Media Microbiology

Microbial Colonization | Cholesteatoma | Otitis Media, Suppurative Chronic

Turkey
Fondation Hôpital Saint-Joseph

Not yet recruiting

Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients With Enterobacterales Bacteremia (MHR-Blood)

Bacteremia
Biohaven Therapeutics Ltd.

Recruiting

BHV-7000 Acute Treatment of Bipolar Mania

Bipolar Disorder

United States
Sohag University

Recruiting

Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo

Vitiligo

Egypt
Hospital Universitari Vall d'Hebron Research Institute
Universitat Pompeu Fabra; IDIAPJgol

Recruiting

Study of the Drivers of Late Diagnosis of Alcohol Related Diseases, Alone or in Combination With Metabolic Dysfunconal Associated Fatty Liver Disease, Implementation and Evaluation of Itnerventions to Reduce Its Burden. (StopALD)

Alcohol Use Disorder | Alcohol-related Liver Disease | Metabolic and Alcohol Related/Associated Liver Disease | Metabolic Disfunction Associated Steatotic Liver Disease

Spain
Vrinnevi Hospital
Ryhov Hospital

Recruiting

Impact of Inflammatory Indexes and Gene Scores in Prediction of Atrial Fibrillation Recurrence Following Electrical Cardioversion (IERV)

Inflammation | Atrial Fibrillation | Genetic Predisposition to Disease

Sweden
Adam S. Kibel, MD
National Cancer Institute (NCI)

Recruiting

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer (PRS)

Prostate Cancer | Polygenic Risk Score

United States
Peking Union Medical College Hospital

Not yet recruiting

A Study to Evaluate the Safety and Tolerability of GEN6050X in Duchenne Muscular Dystrophy. (GEN6050XIIT)

Duchenne Muscular Dystrophy (DMD)
The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Bioavailability Study of Two Different PEG-rhGH Preparations.

Pediatric Growth Hormone Deficiency (PGHD)

China
Ataturk University

Not yet recruiting

The Effect of Mobile-Based Education on Postoperative Recovery and Quality of Life in Thyroidectomy Patients

Thyroid Diseases | Thyroid | Healthy Lifestyle
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
University of Pennsylvania

Not yet recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Parkinson Disease | Alzheimer Disease | ALS | Polyneuropathies | Frontotemporal Dementia | Pheochromocytoma | Thoracic Aortic Aneurysm | Paraganglioma | Genetic Predisposition | Cardiomyopathy Non-ischemic
Sensorion

Not yet recruiting

A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations (AUDIOGENE)

Otorhinolaryngologic Diseases | Ear Diseases | Hearing Disorders | Deafness | Hearing Loss, Sensorineural | Congenital Deafness | DFNB9 | OTOF Gene Mutation

France
Children's Hospital of Philadelphia

Not yet recruiting

ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia

Beta-Thalassemia

United States
National Cancer Institute (NCI)

Not yet recruiting

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Chronic Lymphocytic Leukemia (CLL)

Leukemia, Lymphocytic, Chronic, B-Cell | B-Cell Chronic Lymphocytic Leukemia | B-Lymphocytic Leukemia, Chronic

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Validation of the French ATI Scale and Predisposition to Use Technological Tools in Rehabilitation.

Stroke

Belgium
SpeeDx Pty Ltd
German Federal Ministry of Education and Research; Wellcome Trust; Biomedical... and other collaborators

Not yet recruiting

Susceptibility Testing In Neisseria Gonorrhoeae (STING) Study, Assessing the Performance of a New Rapid Test for Gonorrhoea Antibiotic Resistance, in a Cohort of 100 Culture Positive Neisseria Gonorrhoeae Infections (STING)

Gonorrhea | Diagnosis | Resistance Bacterial
Ractigen Therapeutics.

Recruiting

A Study of RAG-01 in Patients With Non-muscle-invasive Bladder Cancer (NMIBC) Who Have Failed Bacillus Calmette Guérin (BCG) Therapy

Non-Muscle-Invasive Bladder Cancer (NMIBC)

Australia
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Federico II University; Istituto Auxologico Italiano; Università degli Studi...

Recruiting

Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks

Beckwith-Wiedemann Syndrome

Italy
Fondazione Policlinico Universitario Agostino Gemelli...
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Federico II University; Azienda... and other collaborators

Not yet recruiting

Transgender and Gender Diverse Individuals Screening for Breast Cancer (GENESIS)

Breast Cancer
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women

Microbiota | Postoperative Recovery

China
Ataturk University

Recruiting

Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score: Prospective, Randomized Trial

Postoperative Recovery

Turkey
Pfizer

Recruiting

A Study to Learn How the Body Processes the Study Medicine Called Osivelotor (PF-07940367) in People With Loss of Liver Function

Liver Diseases

United States
Simon Fraser University

Recruiting

Impact of Blood Phobia on Fainting Susceptibility

Syncope, Vasovagal | Blood, Injection, Injury Type Phobia

Canada
Ahmet Yuksek

Recruiting

Bispectral Index, Suppression Rate and Emergence Agitation in Spine Surgeries

Emergence Agitation | Anesthesia Recovery | Bispectral Index Monitor

Turkey
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Target of Suv420h1/2 in Hepatocytes

NAFLD

Italy
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Bioequivalence Study of Two Different PEG-rhGH Preparations.

Pediatric Growth Hormone Deficiency (PGHD)

China
National Institute of Allergy and Infectious Diseases...

Recruiting

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Chronic Granulomatous Disease (CGD) | X-Linked Chronic Granulomatous Disease

United States
University of Lausanne Hospitals

Recruiting

A Brief Case Management Intervention for People Involuntarily Admitted to a Psychiatric Hospital (CARP)

Psychiatric Disorder | Involuntary Psychiatric Hospitalization

Switzerland
Janssen Research & Development, LLC

Recruiting

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer (MoonRISe-1)

Non-Muscle Invasive Bladder Cancer

United States, Israel
Changchun GeneScience Pharmaceutical Co., Ltd.
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Long-term Follow-up Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as Reference

Infertility

China
ECOG-ACRIN Cancer Research Group

Not yet recruiting

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Glioblastoma, IDH-Wildtype
Tenaya Therapeutics
Medical University of South Carolina; Johns Hopkins University; University of... and other collaborators

Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (RIDGE)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States, Italy, United Kingdom, France, Sweden, Germany
Beijing Friendship Hospital

Recruiting

Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy

Postoperative Vomiting | Laparoscopic Sleeve Gastrectomy | Postoperative Recovery | Opioid-Free Anesthesia

China
Liverpool University Hospitals NHS Foundation Trust

Not yet recruiting

ADAPT-AST (Adaptive Antimicrobial Susceptibility Testing) (ADAPT-AST)

Urinary Tract Infections
Spark Therapeutics, Inc.

Recruiting

Study of a Gene Therapy Treatment for Hemophilia A (KEYSTONE 1)

Hemophilia A

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

Malignant Solid Neoplasm

United States
Unity Health Toronto

Recruiting

Susceptibility for Entrainment: Role of Ventilator Settings on the Occurrence of Reverse Triggering and Its Physiological Consequences - the SEVeRe Study (SEVERE)

Respiration, Artificial | Reverse Triggering

Canada
Zhongmou Therapeutics

Not yet recruiting

Safety and Efficacy Study of Novel Gene Therapy ZM-02 for Retinitis Pigmentosa Patients (ZM-02)

Retinitis Pigmentosa

China
Suzhou Municipal Hospital

Not yet recruiting

Safety and Efficacy Study of NGGT006 in Refractory Hypercholesterolemia Patients

Familial Hypercholesterolemia | Refractory Hypercholesterolemia
ViGeneron GmbH

Recruiting

Safety and Tolerability of Intravitreal Administration of VG901 in Patients With Retinitis Pigmentosa Due to Mutations in the CNGA1 Gene

Retinitis Pigmentosa

Germany

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