- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06295367
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
Effectiveness of Out-of-Pocket Cost COMmunication and Financial Navigation (CostCOM) in Cancer Patients
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
PRIMARY OBJECTIVE:
I. To compare patient-reported cost-related cancer care non-adherence at 12 months after completion of baseline survey between the enhanced usual care (EUC) and CostCOM study arms.
SECONDARY OBJECTIVES:
I. To compare patient-reported material financial hardship at 12 months after completion of baseline survey between the EUC and CostCOM study arms.
II. To compare patient-reported financial worry at 12 months after completion of baseline survey between the EUC and CostCOM study arms.
III. To compare patient-reported quality of life at 12 months after completion of baseline survey between the EUC and CostCOM study arms.
IV. To compare patient satisfaction with care at 12 months after completion of baseline survey between the EUC and CostCOM study arms.
EXPLORATORY OBJECTIVES:
I. To describe CostCOM (Arm B) patients and their provider experience with various implementation outcomes.
II. To assess accuracy of out-of-pocket estimates communicated with the CostCOM (Arm B) patients at part of the intervention with their reported actual out-of-pocket cost.
III. To compare neighborhood characteristics of patient participants versus (vs.) practice patient population.
IV. To assess patients' satisfaction with CostCOM in patients with Arm B. V. To assess patients' receipt of financial navigation via internal practice or external resources.
VI. To evaluate longitudinal changes in cost-related cancer care non-adherence, material hardship, financial worry, quality of life and satisfaction with care.
OUTLINE:
Non-patient participants: Participants complete surveys and participant in 1 on 1 in depth semi-structured interview over 20-30 minutes at 15-39 months after first patient enrollment.
Patients are randomized to 1 of 2 arms.
ARM A: Patients receive Patient Advocate Foundation (PAF) brochure describing financial navigation services.
ARM B: Patients receive usual financial care per practice standard of care and CostCOM financial counseling sessions over 1 hour within 30 days after enrollment and at 3, 6 and 12 months.
Patients are followed up within 12 months of study intervention completion.
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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Arkansas
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Fort Smith, Arkansas, United States, 72903
- Recruiting
- Mercy Hospital Fort Smith
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Contact:
- Site Public Contact
- Phone Number: 800-378-9373
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Principal Investigator:
- Jay W. Carlson
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Little Rock, Arkansas, United States, 72205
- Recruiting
- CARTI Cancer Center
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 501-906-4199
- Email: Research@CARTI.com
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Illinois
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Alton, Illinois, United States, 62002
- Recruiting
- Saint Anthony's Health
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 618-463-5623
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Centralia, Illinois, United States, 62801
- Recruiting
- Saint Mary's Hospital
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Email: ecog.rss@jimmy.harvard.edu
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Mount Vernon, Illinois, United States, 62864
- Recruiting
- Good Samaritan Regional Health Center
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 618-242-4600
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Kansas
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Garden City, Kansas, United States, 67846
- Recruiting
- Central Care Cancer Center - Garden City
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Principal Investigator:
- Jay W. Carlson
-
Contact:
- Site Public Contact
- Phone Number: 913-948-5588
- Email: aroland@kccop.org
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Great Bend, Kansas, United States, 67530
- Recruiting
- Central Care Cancer Center - Great Bend
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Principal Investigator:
- Jay W. Carlson
-
Contact:
- Site Public Contact
- Phone Number: 913-948-5588
- Email: aroland@kccop.org
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Missouri
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Ballwin, Missouri, United States, 63011
- Recruiting
- Saint Louis Cancer and Breast Institute-Ballwin
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 314-251-7058
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Bolivar, Missouri, United States, 65613
- Recruiting
- Central Care Cancer Center - Bolivar
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Principal Investigator:
- Jay W. Carlson
-
Contact:
- Site Public Contact
- Phone Number: 913-948-5588
- Email: aroland@kccop.org
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Branson, Missouri, United States, 65616
- Recruiting
- Cox Cancer Center Branson
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 417-269-4520
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Joplin, Missouri, United States, 64804
- Recruiting
- Freeman Health System
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Principal Investigator:
- Jay W. Carlson
-
Contact:
- Site Public Contact
- Phone Number: 417-347-4030
- Email: LJCrockett@freemanhealth.com
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Joplin, Missouri, United States, 64804
- Recruiting
- Mercy Hospital Joplin
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 417-556-3074
- Email: esmeralda.carrillo@mercy.net
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Osage Beach, Missouri, United States, 65065
- Recruiting
- Lake Regional Hospital
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 573-302-2768
- Email: clinicaltrials@lakeregional.com
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Rolla, Missouri, United States, 65401
- Recruiting
- Delbert Day Cancer Institute at PCRMC
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 573-458-7504
- Email: research@phelpshealth.org
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Rolla, Missouri, United States, 65401
- Recruiting
- Mercy Clinic-Rolla-Cancer and Hematology
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 573-458-6379
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Saint Joseph, Missouri, United States, 64506
- Recruiting
- Heartland Regional Medical Center
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 816-271-7937
- Email: linda.schumacher@mymlc.com
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Saint Louis, Missouri, United States, 63141
- Recruiting
- Mercy Hospital Saint Louis
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 314-251-7066
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Saint Louis, Missouri, United States, 63109
- Recruiting
- Saint Louis Cancer and Breast Institute-South City
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 314-353-1870
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Saint Louis, Missouri, United States, 63128
- Recruiting
- Mercy Hospital South
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Principal Investigator:
- Jay W. Carlson
-
Contact:
- Site Public Contact
- Phone Number: 314-525-6042
- Email: Danielle.Werle@mercy.net
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Springfield, Missouri, United States, 65804
- Recruiting
- Mercy Hospital Springfield
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Principal Investigator:
- Jay W. Carlson
-
Contact:
- Site Public Contact
- Phone Number: 417-269-4520
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Springfield, Missouri, United States, 65807
- Recruiting
- CoxHealth South Hospital
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Principal Investigator:
- Jay W. Carlson
-
Contact:
- Site Public Contact
- Phone Number: 417-269-4520
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Washington, Missouri, United States, 63090
- Recruiting
- Mercy Hospital Washington
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 636-390-1600
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Ohio
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Belpre, Ohio, United States, 45714
- Recruiting
- Strecker Cancer Center-Belpre
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Contact:
- Site Public Contact
- Phone Number: 800-523-3977
- Email: sheree@columbusccop.org
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Principal Investigator:
- Timothy D. Moore
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Chillicothe, Ohio, United States, 45601
- Recruiting
- Adena Regional Medical Center
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 877-779-7585
- Email: sheree@columbusccop.org
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Columbus, Ohio, United States, 43213
- Recruiting
- Mount Carmel East Hospital
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Columbus, Ohio, United States, 43219
- Recruiting
- The Mark H Zangmeister Center
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Columbus, Ohio, United States, 43222
- Recruiting
- Mount Carmel Health Center West
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-234-5433
- Email: sheree@columbusccop.org
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Gahanna, Ohio, United States, 43230
- Recruiting
- Central Ohio Breast and Endocrine Surgery
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2745
- Email: sheree@columbusccop.org
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Grove City, Ohio, United States, 43123
- Recruiting
- Mount Carmel Grove City Hospital
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 877-779-7585
- Email: sheree@columbusccop.org
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Grove City, Ohio, United States, 43123
- Recruiting
- Zangmeister Center Grove City
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2745
- Email: sheree@columbusccop.org
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Lancaster, Ohio, United States, 43130
- Recruiting
- Fairfield Medical Center
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 740-687-8863
- Email: sheree@columbusccop.org
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Lima, Ohio, United States, 45801
- Recruiting
- Saint Rita's Medical Center
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Principal Investigator:
- Timothy D. Moore
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Contact:
- Site Public Contact
- Phone Number: 419-226-9617
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Marietta, Ohio, United States, 45750
- Recruiting
- Marietta Memorial Hospital
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Contact:
- Site Public Contact
- Phone Number: 800-523-3977
- Email: sheree@columbusccop.org
-
Principal Investigator:
- Timothy D. Moore
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Marysville, Ohio, United States, 43040
- Recruiting
- Memorial Hospital
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Principal Investigator:
- Timothy D. Moore
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Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Mount Vernon, Ohio, United States, 43050
- Recruiting
- Knox Community Hospital
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Principal Investigator:
- Timothy D. Moore
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Contact:
- Site Public Contact
- Phone Number: 740-393-9000
- Email: sheree@columbusccop.org
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New Albany, Ohio, United States, 43054
- Recruiting
- Mount Carmel New Albany Surgical Hospital
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Principal Investigator:
- Timothy D. Moore
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Contact:
- Site Public Contact
- Phone Number: 614-488-2745
- Email: sheree@columbusccop.org
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Newark, Ohio, United States, 43055
- Recruiting
- Licking Memorial Hospital
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Principal Investigator:
- Timothy D. Moore
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Contact:
- Site Public Contact
- Phone Number: 740-348-4000
- Email: sheree@columbusccop.org
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Newark, Ohio, United States, 43055
- Recruiting
- Newark Radiation Oncology
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Perrysburg, Ohio, United States, 43551
- Recruiting
- Mercy Health Perrysburg Cancer Center
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Portsmouth, Ohio, United States, 45662
- Recruiting
- Southern Ohio Medical Center
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Springfield, Ohio, United States, 45504
- Recruiting
- Springfield Regional Cancer Center
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Contact:
- Site Public Contact
- Phone Number: 937-528-2900
- Email: clinical.trials@daytonncorp.org
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Principal Investigator:
- Timothy D. Moore
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Springfield, Ohio, United States, 45505
- Recruiting
- Springfield Regional Medical Center
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Contact:
- Site Public Contact
- Phone Number: 937-528-2900
- Email: clinical.trials@daytonncorp.org
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Principal Investigator:
- Timothy D. Moore
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Toledo, Ohio, United States, 43608
- Recruiting
- Saint Vincent Mercy Medical Center
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Principal Investigator:
- Timothy D. Moore
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Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Toledo, Ohio, United States, 43623
- Recruiting
- Mercy Health - Saint Anne Hospital
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-488-2118
- Email: sheree@columbusccop.org
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Westerville, Ohio, United States, 43081
- Recruiting
- Saint Ann's Hospital
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 614-234-5433
- Email: sheree@columbusccop.org
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Wilmington, Ohio, United States, 45177
- Recruiting
- Clinton Memorial Hospital
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Principal Investigator:
- Timothy D. Moore
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Contact:
- Site Public Contact
- Phone Number: 937-283-2273
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Zanesville, Ohio, United States, 43701
- Recruiting
- Genesis Healthcare System Cancer Care Center
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Principal Investigator:
- Timothy D. Moore
-
Contact:
- Site Public Contact
- Phone Number: 740-454-5232
- Email: sheree@columbusccop.org
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Oklahoma
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Oklahoma City, Oklahoma, United States, 73120
- Recruiting
- Mercy Hospital Oklahoma City
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Principal Investigator:
- Jay W. Carlson
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Contact:
- Site Public Contact
- Phone Number: 405-752-3402
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- NON-PATIENTS PARTICIPANTS: Participant must speak English
- NON-PATIENTS PARTICIPANTS: Participant must be employed at National Cancer Institute Community Oncology Research Program (NCORP) site for at least six months
- NON-PATIENTS PARTICIPANTS: Participant must be able to provide informed consent to participate in this study
NON-PATIENTS PARTICIPANTS: Participant must be one of the following:
- A study coordinator with a role involving use of CostCOM intervention price transparency and financial navigation platform
- A practice oncology provider (i.e., physician or mid-level), or
- A practice financial counselor, social workers, financial navigators, or pharmacist who have provided care or been in contact (in the last 3 months) to a patient who was assigned to the CostCOM arm, and who completed the at least 6 month study follow-up
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must be ≥ 18 years of age
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must be fluent in written and spoken English OR patient must be fluent in written and spoken Spanish
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must be within 120 days of a new diagnosis of any solid cancer of any stage at the time of Step 0
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must have had their first medical oncology visit at the time of Step 0
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must have initiated oral or intravenous (IV) cancer systemic therapy or have received a prescription order with stated intent to initiate within 30 days following Step 0 consent
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patients must not have indolent cancer undergoing observation alone (i.e., active surveillance)
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patients must not be receiving palliative or hospice care alone
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must not be undergoing curative surgery alone or radiation therapy alone. (Must be receiving systemic therapy), unless they are receiving systemic therapy
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must confirm that they intend to receive their care or monitoring at one of the participating NCORP practices
PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must have the ability to understand and the willingness to sign a written informed consent document.
- Patients with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) or caregiver and/or family member available are not eligible
PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must not have an Eastern Cooperative Oncology Group (ECOG) performance status ≥ 3, OR
- Patient must not be deemed medically unable to participate in the study by the study investigators or an oncology clinician (i.e., referral to hospice)
- PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must not be enrolled in treatment clinical trials where cancer systemic therapy is provided at no cost to the patient
PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must not be enrolled in EAQ221CD or S1912CD given financial navigation is offered as part of these two trials.
- NOTE: If S1912CD is activated in a participating practice, S1912CD should be offered first to patients with metastatic cancer meeting eligibility criteria for S1912CD. Only if a patient is not eligible or not interested in participating in S1912CD, the EAQ222CD can be offered. For early stage cancer, EAQ222CD can be offered first given S1912CD does not enroll patients with early stage cancer
PATIENT ELIGIBILITY CRITERIA FOR STEP 0 (OPEN SCREENING REGISTRATION): Patient must not be enrolled in other clinical trials where OOPC communication or financial navigation (i.e., professional guidance to identify financial assistance programs to alleviate cost of care) is being offered as part of the trial
- NOTE: If a trial is offering financial counseling alone without financial navigation patients are allowed to co-enroll
- NOTE: Gift cards for survey completion, or parking passes are not considered financial navigation
- PATIENT ELIGIBILITY CRITERIA FOR STEP 1 (OPEN RANDOMIZATION): Patient must meet all the eligibility criteria for step 0
- PATIENT ELIGIBILITY CRITERIA FOR STEP 1 (OPEN RANDOMIZATION): Patient must have signed a written informed consent form
- PATIENT ELIGIBILITY CRITERIA FOR STEP 1 (OPEN RANDOMIZATION): Patient must have a completed baseline survey in ECOG American College of Radiology Imaging Network Systems for Easy Entry of Patient Reported Outcomes (EASEE-PRO) within 30 days of the date of OPEN registration and consent (step 0)
- PATIENT ELIGIBILITY CRITERIA FOR STEP 1 (OPEN RANDOMIZATION): Patients must have initiated their cancer treatment (i.e., IV or oral systemic therapy) either before or within 30 days of the date of OPEN registration and consent (step 0)
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Health Services Research
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: ARM A (Enhanced usual care)
Patients receive PAF brochure describing financial navigation services.
|
Ancillary studies
Receive PAF brochure describing financial navigation services
Other Names:
|
Experimental: ARM B (CostCOM)
Patients receive usual financial care per practice standard of care and CostCOM financial counseling sessions over 1 hour within 30 days after enrollment and at 3, 6 and 12 months.
|
Ancillary studies
Receive PAF brochure describing financial navigation services
Other Names:
Receive CostCOM financial counseling
Other Names:
|
Experimental: Non-patient participants: (interview)
Non-patient participants complete surveys and participant in 1 on 1 in depth semi-structured interview over 20-30 minutes at 15-39 months after first patient enrollment.
|
Ancillary studies
Participate in a 1 on 1 in-depth interview
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Cost-related cancer care non-adherence
Time Frame: 12 months
|
Cost-related cancer care non-adherence is defined as a positive response to any of the following due to costs: Delayed, forewent, stopped, or changed prescribed cancer medication; or delayed, forewent, or refused recommended cancer tests, or cancer office visits.
Will be calculated as a report of non-adherence at any point up through the 12mo follow-up survey.
|
12 months
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Rate of Material Financial Hardship
Time Frame: at 12 months
|
Rate of material hardship at each time point is a binary (yes/no) composite measure defined as a positive response to any of the following: (1) home sale, refinance or move to affordable rental, (2) loans, (3) reaching credit limits, and (4) bankruptcy because of your cancer care, or its treatment (adapted from Medical Expenditure Panel Survey).Material hardship at 12 months is measured as report of material hardship at any of the 3, 6 and 12 follow-ups.
|
at 12 months
|
Patient-reported financial worry
Time Frame: At baseline and at 3, 6 and 12 months
|
Measured by 12-item Comprehensive Score for Financial Toxicity (de Souza COST measure).
Composite Scores range between 0-44 with higher the scores reflecting better the Financial Well-Being.
Item 12 , an unscored summary item, will be used separately as a single item measure of financial worry.
Mean score and changes in mean scores from baseline at each time point between the arms will be compared using two-sample t-tests.
|
At baseline and at 3, 6 and 12 months
|
Patient-reported satisfaction with care at 12 months
Time Frame: At baseline and at 3, 6 and 12 months
|
Satisfaction with the care will be measured using Consumer Assessment of Healthcare Providers and Systems (CAHPS) Cancer Care Survey questions.
Composite items are rated on a scale of 0 to 10, with 0 being the worst and 10 being the best.
Mean score and changes in mean scores from baseline at each time point between the arms will be compared using two-sample t-tests.
|
At baseline and at 3, 6 and 12 months
|
Patient-reported Quality of life - mental and physical health
Time Frame: At baseline and at 3, 6 and 12 months
|
Measured using the 10-item Patient-Reported Outcomes Measurement Information System (PROMIS-10) version 1.2 Global Health.
A T-score will be calculated for each of the global mental health and global physical health sections with a higher PROMIS T-score representing more of the concept being measured (mental/physical health).
T-scores for the general population have a mean of 50 and a standard deviation (SD) of 10.Thus, a person who has T- scores of 60 for the Global Physical Health or Global Mental Health scales is one standard deviation better (more healthy) than the general population Mean score and changes in mean scores from baseline at each time point between the arms will be compared using two-sample t-tests.
|
At baseline and at 3, 6 and 12 months
|
Other Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Out of pocket cost (OOPC) accuracy
Time Frame: At 3, 6 and 12 months
|
Mean absolute difference between OOPC estimates for the first cycle of therapy (as estimated by TailorMed Medical Incorporated) and the actual billed out of pocket (OOP) costs (as reported by patients based on their co-pays or medical bills).
|
At 3, 6 and 12 months
|
Proportion of study patient participants that are of minority racial/ethnic background, and with public insurance will be measured and compared with that of practice patient population.
Time Frame: Up to 12 months
|
Proportion of patients with specific characteristics, including racial, ethnic, payer mix, and neighborhood deprivation indices.
Proportions will be compared between study participants and practice patient population.
|
Up to 12 months
|
Patient reported satisfaction with intervention
Time Frame: 39 months after enrollment of first study participant
|
Qualitative interviews utilizing the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) framework was used to guide the evaluation questions and examine the effectiveness of the intervention and implementation outcomes. Participants describe their experience with various components of the CostCOM intervention: price transparency, financial navigation, and financial counseling, barriers and facilitators to participation, and feedback on what they liked and disliked about CostCOM, how it impacted their care, satisfaction with care, and what they would change to make it more helpful or engaging. The outcome measures are the proportion of subjects in the top 10 categories identified (5 for each like and dislike) |
39 months after enrollment of first study participant
|
Receipt of financial navigation via internal practice or external resources
Time Frame: 12 months
|
Proportion of subjects receiving (at least 1 session) of financial navigation via study intervention, internal practice, or external resources. Receipt of financial counseling or financial assistance will be documented via treating clinic as extracted from medical records and intervention participants via reports from TailorMed Medical Incorporated |
12 months
|
Evaluate longitudinal changes in Cost-related cancer care non-adherence, material hardship, financial worry, quality of life and satisfaction with care
Time Frame: At baseline and at 3, 6 and 12 months
|
Cost-related cancer care outcomes of non-adherence, material hardship, financial worry, quality of life and satisfaction with care (reported above) are included in a Regression Model (GEE)
|
At baseline and at 3, 6 and 12 months
|
longitudinal changes in cost-related cancer care non-adherence
Time Frame: At baseline, 3, 6 and 12 months
|
The effect of time (unitless Betas (slope)) will be estimated using a regression model (stage-stratified GEE analyses) for the Cost-related Outcomes non-adherence, material hardship, financial worry, quality of life, and satisfaction with care Regression intervention parameter (COSTCOM v EUC) will use EUC as the reference category. Cost-related cancer care non-adherence is defined as a positive response to any of the following due to costs: Delayed, forewent, stopped, or changed prescribed cancer medication; or delayed, forewent, or refused recommended cancer tests, or cancer office visits |
At baseline, 3, 6 and 12 months
|
longitudinal changes in cost-related cancer care material hardship
Time Frame: At baseline, 3, 6 and 12 months
|
The effect of time (unitless Betas (slope)) will be estimated using a regression model (stage-stratified GEE analyses) for the Cost-related Outcomes non-adherence, material hardship, financial worry, quality of life, and satisfaction with care Regression intervention parameter (COSTCOM v EUC) will use EUC as the reference category. Material hardship is a binary (yes/no) composite measure defined as a positive response to any of the following: (1) home sale, refinance or move to affordable rental, (2) loans, (3) reaching credit limits, and (4) bankruptcy because of your cancer care, or its treatment (adapted from Medical Expenditure Panel Survey). |
At baseline, 3, 6 and 12 months
|
longitudinal changes in cost-related cancer care financial worry
Time Frame: At baseline, 3, 6 and 12 months
|
The effect of time (unitless Betas (slope)) will be estimated using a regression model (stage-stratified GEE analyses) for the Cost-related Outcomes non-adherence, material hardship, financial worry, quality of life, and satisfaction with care Regression intervention parameter (COSTCOM v EUC) will use EUC as the reference category. Financial Worry measured by the 12-item Comprehensive Score for Financial Toxicity (de Souza COST measure). Composite Scores range between 0-44 with higher the scores reflecting better the Financial Well-Being. Item 12 , an unscored summary item, will be used separately as a single item measure of financial worry. Mean score and changes in mean scores from baseline at each time point between the arms will be compared using two-sample t-tests. |
At baseline, 3, 6 and 12 months
|
longitudinal changes in cost-related cancer care quality of life
Time Frame: At baseline, 3, 6 and 12 months
|
The effect of time (unitless Betas (slope)) will be estimated using a regression model (stage-stratified GEE analyses) for the Cost-related Outcomes non-adherence, material hardship, financial worry, quality of life, and satisfaction with care Regression intervention parameter (COSTCOM v EUC) will use EUC as the reference category. Quality of life is measured using the 10-item Patient-Reported Outcomes Measurement Information System (PROMIS-10) ver 1.2 Global Health. A T-score will be calculated for each global mental health and global physical health sections with a higher PROMIS T-score representing more of the concept being measured (mental/physical health). T-scores for the general population have a mean of 50 and a standard deviation (SD) of 10.Thus, a person who has T- scores of 60 for the Global Physical Health or Global Mental Health scales is one standard deviation better (more healthy) than the general population Mean score and changes in mean scores from base |
At baseline, 3, 6 and 12 months
|
longitudinal changes in cost-related cancer care satisfaction with care
Time Frame: At baseline, 3, 6 and 12 months
|
The effect of time (unitless Betas (slope)) will be estimated using a regression model (stage-stratified GEE analyses) for the Cost-related Outcome Satisfaction with care Regression intervention parameter (COSTCOM v EUC) will use EUC as the reference category. Satisfaction with the care is measured using the Consumer Assessment of Healthcare Providers and Systems (CAHPS) Cancer Care Survey questions. Composite items are rated on a scale of 0 to 10, with 0 being the worst and 10 being the best. |
At baseline, 3, 6 and 12 months
|
Collaborators and Investigators
Sponsor
Collaborators
Investigators
- Principal Investigator: Gelareh Sadigh, ECOG-ACRIN Cancer Research Group
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- EAQ222CD (Other Identifier: CTEP)
- UG1CA189828 (U.S. NIH Grant/Contract)
- NCI-2023-09944 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
- ECOG-ACRIN-EAQ222CD (Other Identifier: DCP)
- R01CA272680 (U.S. NIH Grant/Contract)
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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