Search clinical trials for: bridion

Total 105 results

Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017)

Anesthesia, General
University of South Florida
Merck Sharp & Dohme LLC

Completed

Study to Determine if Administration of Sugammadex Impacts Hospital Efficiency

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Efficacy, Safety and Pharmacokinetics of Sugammadex (Org 25969; MK-8616) at 3 Different Time Points After 0.6 mg/kg Esmeron® in Male Participants (P05940; MK-8616-020).

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Japanese Participants. Part A (P05957)

Anesthesia, General
Algemeen Ziekenhuis Maria Middelares

Withdrawn

Effect of NMBA on Surgical Conditions in THR

Postoperative Pain | Surgery

Belgium
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Caucasian Participants. Part B (P05974)

Anesthesia, General
Erasme University Hospital

Completed

Minimal Optimal Dose of Sugammadex in Elective Surgery

Time of a TOF Ratio >0,9

Belgium
Merck Sharp & Dohme LLC

Completed

Dose-Finding Trial With Sugammadex Administered at 3 and 15 Minutes After 1.0 and 1.2 mg/kg Rocuronium Bromide in Participants of ASA Class 1-3 (P05944; MK-8616-024)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Org 25969 Administered After Zemuron® (MK-8616-042)

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Sugammadex Hypersensitivity Study (Study P06042)

Hypersensitivity
Federal Research Institute of Pediatric Hematology...

Unknown

the Efficacy and Safety of Sugammadex in Children 0-2 Years Old

Anesthesia | Pediatric Cancer | Beta-Thalassemia | Hepatic Metastases | Pediatric Tumor | Pediatric Hepatoblastoma

Russian Federation
Attikon Hospital

Completed

Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children

Anesthesia; Functional

Greece
Merck Sharp & Dohme LLC

Completed

A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982)

Gallbladder Disease

Germany, Italy
Seoul National University Bundang Hospital

Completed

Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery

Neuromuscular Block, Residual

Korea, Republic of
KK Women's and Children's Hospital
Singhealth Foundation

Completed

Sugammadex Versus Neostigmine for Postoperative Nausea and Vomiting After Laparoscopic Gynaecological Surgery

Postoperative Nausea and Vomiting

Singapore
Seoul National University Bundang Hospital
MSD Korea Ltd.

Completed

Neuromuscular Blockade During Transurethral Resection of Bladder Cancer

Neuromuscular Blockade

Korea, Republic of
University Hospital Olomouc
Palacky University

Completed

Deep Neuromuscular Block During General Anaesthesia in Robotic Surgery

Observation of Neuromuscular Block | Complication of Ventilation Therapy | Postoperative Recovery

Czechia
Ain Shams University

Completed

The Effect of Sugammadex Given Based on Ideal, Actual or Adjusted Body Weight on Reversal of Rocuronium.

Muscle Relaxation

Egypt
Ziekenhuis Oost-Limburg
Merck Sharp & Dohme LLC

Completed

CURES: The Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity (CURES)

Obesity | Surgical Conditions | Respiratory Function | Laparoscopic Gastric Bypass Surgery | Cerebral Tissue Oxygenation

Belgium
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex With Neostigmine as Reversal Agents for Rocuronium at Reappearance of T2 (Study P06101) (DANCHEONG)

Neuromuscular Blockade
Hopital Foch

Completed

Recovery Effect of Sugammadex Measured by Bispectral and Neurosense Indices (Sugarecovery)

Anesthesia

France
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex With Neostigmine During Laparoscopic Cholecystectomy or Appendectomy (P05699)

Anesthesia, General
Universiti Sains Malaysia

Completed

Comparing Reversal With Neostigmine and Sugammadex in Paediatric (JS)

Neuromuscular Blockade

Malaysia
Leiden University Medical Center

Completed

Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery Profile (Neuropa)

Postoperative Respiratory Condition

Netherlands
University of Edinburgh
University of Peradeniya

Completed

A Pilot Study Using Rocuronium to Prevent Intermediate Syndrome After Organophosphorus Insecticide Poisoning

Organophosphate Poisoning

Sri Lanka
University of Florence
Merck Sharp & Dohme LLC

Unknown

Recovery of Muscle Function After Deep Neuromuscular Block by Means of Diaphragm Ultrasonography

Post-operative Residual Curarization

Italy
Baskent University

Completed

Sugammadex Given for the Reversal of Rocuronium Induced Neuromuscular Blockade Under Sevoflurane Anesthesia in Infants

Brain Cancer
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Improvement of Facial Nerve Monitoring in Parotid Surgery by Sugammadex

Injury to Nerve During Surgery

Taiwan
Cairo University
National Liver Institute, Egypt

Completed

Sugammadex Versus Neostigmine in Patients With Liver Cirrhosis Undergoing Liver Resection

Cirrhosis and Chronic Liver Disease

Egypt
University of Medicine and Pharmacy at Ho Chi Minh...
Merck Sharp & Dohme LLC

Unknown

Deep Neuromuscular Block and Sugammadex Versus Standard of Care on Quality of Recovery in Patient Undergo Elective Laparoscopic Cholecystectomy

Neuromuscular Block

Vietnam
Konkuk University Medical Center

Unknown

The Clinical Changes Before and After Sugammadex in the Patients Undergoing Hip Surgery on the Aspect of Delirium

Delirium

Korea, Republic of
Onze Lieve Vrouw Hospital

Completed

Electromyographic Activity of the Respiratory Muscles During Neostigmine or Sugammadex Enhanced Recovery After Neuromuscular Blockade (REDNESII)

Respiratory Muscles | Electromyography

Belgium
Chonnam National University Hospital

Unknown

Compare of Surgical Condition and Complications With Moderate and Deep NM Block (MISPCNUHH)

Neuromuscular Blockade

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

Comparison of 2.0 mg/kg Sugammadex and Neostigmine at Reappearance of T2 in Chinese and European Subjects (Study 19.4.324)(P05768AM1)(COMPLETED)

Anesthesia, General | Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of 4.0 mg/kg Sugammadex at 1-2 PTC in Chinese and European Subjects (Study 19.4.335)(P05775AM1)(COMPLETED)

Anesthesia, General | Neuromuscular Blockade
Korea University Anam Hospital

Unknown

Effectiveness of Sugammadex in LMS Surgery

Muscle Relaxation
Merck Sharp & Dohme LLC

Completed

Comparing 4.0 mg.Kg-1 Sugammadex With Placebo in the Reversal of Profound Neuromuscular Blockade (P05767)

Anesthesia | Neuromuscular Blockade
Hospital Sultanah Aminah Johor Bahru

Completed

Optimal Relaxation Technique for Laparotomies With Rocuronium Infusion Followed by Sugammadex Reversal (ProjectO5Rs)

Underdosing of Skeletal Muscle Relaxants for Laparotomy | Reversal of Skeletal Muscle Relaxant

Malaysia
Merck Sharp & Dohme LLC

Completed

Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED)

Neuromuscular Blockade
Onze Lieve Vrouw Hospital
Universiteit Antwerpen; MSD Belgium BVBA

Completed

Functional Respiratory Imaging After Neostigmine or Sugammadex (FRINeoS)

Respiratory-Gated Imaging Techniques

Belgium
Merck Sharp & Dohme LLC

Completed

Relation Between TOF-Watch® SX and a Peripheral Nerve Stimulator After 4.0 mg.Kg-1 Sugammadex (P05698)

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Observational Study to Evaluate the Current Neuromuscular Monitoring Practice Used After Different Types of Surgery, for Which Neuromuscular Blocking Agents Were Used, With or Without Blocking Reversal (P06556)

Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774)

Anesthesia
Merck Sharp & Dohme LLC

Completed

Dialysis of Sugammadex in Participants With Severe Renal Impairment (Study 19.4.333) (P05773)

Neuromuscular Blockade
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Evaluation of Accelerometer-Based Neuromuscular Monitoring Reliability to Exclude Postoperative Residual Paralysis

Postoperative Residual Paralysis

Italy
Kocaeli University

Completed

Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients

Pre-eclampsia Aggravated

Turkey
St. Antonius Hospital

Unknown

Pilot Study on the Pharmacodynamics of Sugammadex in Morbidly Obese Patients: Reversal of Deep Neuromuscular Blockade (MOS)

Neuromuscular Blockade

Netherlands
Federal University of São Paulo
Hospital General Universitario Santa Lucia

Completed

Efficacy and Safety of Sugammadex in Renal Diseased Patients

Kidney Failure, Chronic | Neuromuscular Blockade

Brazil
University of Patras

Unknown

Comparative Study of Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade in Morbidly Obese Patients

Morbid Obesity | Neuromuscular Blockade

Greece

3

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