Search clinical trials for: cytokine inhibitor

Total 69214 results

National Institute of Neurological Disorders and...

Completed

Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade

Glioblastoma

United States
Arun Aneja

Completed

Inflammatory Markers in Trauma Patient Outcomes

Polytrauma

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); Novartis; Lymphoma Research Foundation

Completed

Universal Granulocyte Macrophage-colony Stimulating Factor (GM-CSF)-Producing and GM.CD40L for Autologous Tumor Vaccine in Mantle Cell Lymphoma

Lymphoma

United States
Aveni Foundation

Withdrawn

CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 (CORONA)

COVID-19 | Acute Respiratory Distress Syndrome | Cytokine Storm
Alexandria University
Science and Technology Development Fund (STDF), ,Egypt

Completed

Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital

Pulmonary Fibrosis | Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome

Egypt
Boston Medical Center

Terminated

Etoposide in Patients With COVID-19 Infection

COVID-19

United States
Fundacion para la Formacion e Investigacion Sanitarias...

Completed

Defibrotide as Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome of Covid 19. (DEFACOVID)

COVID19

Spain
Herlev and Gentofte Hospital

Completed

Impact of LTBI Treatment on Glucose Tolerance and Chronic Inflammation

Diabetes Mellitus, Type 2 | Latent Tuberculosis

Denmark
Nektar Therapeutics
Bristol-Myers Squibb

Terminated

Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence (PIVOT-12)

Melanoma | Melanoma (Skin) | Melanoma Stage IV | Melanoma Stage III

United States, Spain, Germany, France, Australia, Italy, Greece, Israel, Russian Federation, New Zealand, Austria, United Kingdom, Netherlands, Portugal, Poland, Czechia, Romania
Nektar Therapeutics
Bristol-Myers Squibb

Terminated

A Study of Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)

Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma

United States, Argentina, Brazil, Australia, Singapore, New Zealand, Russian Federation, Mexico, Peru, Chile
University Hospital, Tours

Completed

Prospective Study to Evaluate the Blood Kinetics of Immune Cells and Immunosuppressive Cytokines After Exposure to an Immunity Checkpoint Inhibitor (ICI): Study of the Impact of Chemotherapy (CINECI)

Non Small Cell Lung Cancer | Bladder Cancer | ENT Cancer

France
Jewish General Hospital
Novartis Pharmaceuticals

Terminated

Dose Escalation Study of Gleevec and Chlorambucil in Previously Treated Chronic Lymphocytic Leukemia Patients (GL-CLB-001)

Chronic Lymphocytic Leukemia

Canada
Bristol-Myers Squibb
Nektar Therapeutics

Terminated

A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer (PIVOT IO 020)

Ewing Sarcoma | Ependymoma | Medulloblastoma | Neuroblastoma | Rhabdomyosarcoma | High-grade Glioma | Leukemia and Lymphoma | Miscellaneous Brain Tumors | Miscellaneous Solid Tumors | Relapsed, Refractory Malignant Neoplasms

United States, Australia, France, Germany, Italy, Spain
Nektar Therapeutics

Terminated

Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors (PROPEL)

Non-Small Cell Lung Cancer

United States, Germany, Spain, Australia, France
Ain Shams University
Misr International University

Completed

Effect of Pentoxifylline on Prognosis of Coronavirus Disease 2019 (COVID- 19) Infection

Covid19 | Corona Virus Infection | Cytokine Storm

Egypt
Vitreo-Retinal Associates, Michigan
Genentech, Inc.; Michigan State University

Completed

Analysis of Cytokines in Response to Treatment of Diabetic Macular Edema With 0.3mg Lucentis

Diabetic Macular Edema

United States
University of Toledo Health Science Campus

Completed

Fluoxetine to Reduce Intubation and Death After COVID19 Infection

COVID-19 | Cytokine Storm

United States
Shanghai Mental Health Center
Shanghai Pudong New Area Mental Health Center; The Affiliated Brain Hospital...

Completed

Disturbance of Plasma Cytokine Parameters in Clozapine-Resistant Treatment-Refractory Schizophrenia (CTRS) and Their Association With Combination Therapy

Schizophrenia

China
Saiful Anwar Hospital

Completed

Vitamin D and Curcumin Piperine Attenuates Disease Activity and Cytokine Levels in Systemic Lupus Erythematosus Patients

Systemic Lupus Erythematosus

Indonesia
Hospital General de México Dr. Eduardo Liceaga
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran; CCINSHAE... and other collaborators

Terminated

Safety and Efficacy of Maraviroc and/or Favipiravir With Standard Therapy in Severe COVID-19 Adults (COMVIVIR)

COVID-19

Mexico
MetroHealth Medical Center

Completed

ICE T for Post GYN Surgery Pain

Opioid Substitution Treatment

United States
National Jewish Health

Completed

Phase II Study of Digitoxin to Treat Cystic Fibrosis

Cystic Fibrosis

United States
Philogen S.p.A.

Terminated

Combination Therapy of L19IL2 and Gemcitabine in Advanced Pancreatic Cancer Patients

Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection

Italy, Germany
Fundacion GenesisCare
Hospital La Milagrosa; Hospital Vithas Valencia Consuelo

Suspended

Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 (ULTRA-COVID)

Pneumonia, Viral | Cytokine Storm

Spain
Inmune Bio, Inc.

Terminated

INB03 for the Treatment of Pulmonary Complications From COVID-19

COVID-19

United States
Anqing Municipal Hospital
The First Affiliated Hospital of Anhui Medical University

Completed

Dexmedetomidine Combined With Lidocaine Infusion Affect Inflammation Cytokines

Anesthesia; Reaction

China
Incyte Corporation

Terminated

Assessment of Efficacy and Safety of Ruxolitinib in Participants With COVID-19-Associated ARDS Who Require Mechanical Ventilation (RUXCOVID-DEVENT)

COVID-19

United States, Russian Federation
University Hospital, Basel, Switzerland
Pharming Technologies B.V.

Terminated

Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19

Coronavirus Infections

Switzerland, Brazil, Mexico
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil (OM) on QT/QTc Intervals in Healthy Adults

QT Intervals Changes | QTc Intervals Changes

United Kingdom
University of Colorado, Denver

Withdrawn

Safety and Efficacy of Baricitinib for COVID-19

COVID-19

United States
University of Colorado, Denver

Withdrawn

Safety and Efficacy of Ruxolitinib for COVID-19

COVID-19
South Valley University

Completed

Platelet-rich Plasma and Synovial Cytokines in Knee Osteoarthritis

Knee Osteoarthritis

Egypt
All India Institute of Medical Sciences, New Delhi

Completed

Candida Associated Cytokines in Oral Leukoplakia

Oral Leukoplakia

India
TCI Co., Ltd.

Completed

Investigation of the Efficacies of a Resveratrol Formula on Improvement of Skin Conditions and Inflammatory Related Factors (Resveratrol)

Skin Conditions | Proinflammatory Cytokines

Taiwan
Milton S. Hershey Medical Center

Withdrawn

Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19)

Covid19

United States
University Hospital, Geneva

Completed

Swiss PACK-CXL Multicenter Trial for the Treatment of Infectious Keratitis

Keratitis; Infectious Disease (Manifestation)

Switzerland
Mercy Health Ohio

Terminated

Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens

Open Fracture | Post-Op Wound Infection

United States
Johann Wolfgang Goethe University Hospital

Withdrawn

Functional Improvement of Progenitor Cells and Endothelial Function by Vildagliptin in Diabetes Mellitus (FINNjA-DM). (FINNjA-DM)

SDF-1 is an Important Cytokine for Neovascularization. Cleavage of SDF-1 is Reduced by DPPIV Inhibitors

Germany
Yonsei University

Completed

Effect of Sodium Glucose Co-transporter 2 Inhibitor on Inflammatory Cytokine in Type 2 Diabetes

Type2 Diabetes Mellitus

Korea, Republic of
Norma Osama Abdalla Zayed
Abdelhamid, Bassant Mohamed, M.D.

Completed

Effect of IV Infusion of Lidocaine Compared to IV Infusion of Dexmedetomidine on Proinflammatory Cytokines

Inflammatory Response

Egypt
UNICEF
Pak Emirates Military Hospital Rawalpindi

Completed

Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan

Critical Illness | Covid19 | ARDS | Cytokine Release Syndrome

Pakistan
Centre Antoine Lacassagne
Institut National de la Santé Et de la Recherche Médicale, France

Completed

ELR+CXCL Cytokines in Metastatic Kidney Cancers: Predictive Markers of Resistance to Sunitinib (SUNITRES)

Metastatic Kidney Cancers

France
Tianjin Medical University Cancer Institute and...

Unknown

Study of PD-1 Inhibitor Combination With Autologous Cell Immunotherapy in the Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma

China
Tianjin Medical University Cancer Institute and...

Unknown

Study of Autologous CIK Cell Immunotherapy Combination With PD-1 Inhibitor and Chemotherapy in the Advanced NSCLC

Non-small Cell Lung Cancer | First-line Treatment

China
Amgen

Completed

AMG 386 Phase 2 Open-Label Renal Cell Carcinoma (RCC) Study 1st Line or After Cytokine Failure in Combination With Sunitinib

Advanced Renal Cell Carcinoma
Instituto Dante Pazzanese de Cardiologia

Completed

Systemic Inflammatory Response Evaluation With the Use of Inhaled Anesthetic Sevoflurane During CPB

Inflammatory Response

Brazil
Alexandria University
Science, Technology & Innovation Funding Authority (STIFA), Egypt

Unknown

The Safety & Efficacy of Imatinib for the Treatment of SARS-COV-2 Induced Pneumonia

COVID-19
Chuncheon Sacred Heart Hospital
Hallym University

Completed

The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block

Postoperative Pain | Dexmedetomidine | Suprascapular Nerve Block | Arthroscopic Rotator Cuff Repair | Axillary Nerve Block | Pain Related Cytokine

Korea, Republic of
University of California, San Francisco
Astellas Pharma Inc

Completed

NFAT-Dependent Cytokine Gene Expression for Immune Monitoring in Kidney Transplant Patients

Kidney Transplantation

United States
University of Molise
University of Roma La Sapienza; Cliniche Humanitas Gavazzeni; Ospedale Humanitas... and other collaborators

Completed

Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy

Diabetic Retinopathy

Italy

Search clinical trials for: cytokine inhibitor

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